Faculty Brochure

Transcription

Faculty Brochure

SCHOOL OF
MATERIALS SCIENCE
2014
National University Corporation
Japan Advanced Institute of Science and Technology
School of Materials Science
Exploring atomic and molecular science using cutting-edge technology,
we design functional materials, organize these materials to
fabricate advanced devices to be used for the good of society.
Materials
Characterization
and Device Fabrication
Physics labs
From exploration of new
materials to
development of next
generation electronics
and photonics
New Materials
Design
and Synthesis
Open Frontier Fields
and
achieve breakthroughs
based on
materials science
Biofunction
and
Organization
Chemistry labs
Biology labs
Development of
nanostructured materials with
novel functions and
high performance
Bio-guided materials
science and harmonization
of materials with
biofunctions
Contents
Message from the Dean of the School of Materials Science
P1
Admissions and Expenses
P2
Financial Support
P3
Material Voice
P4-6
Materials Characterization and Device Fabrication (Physics)
P7-13
New Materials Design and Synthesis (Chemistry)
P14-18
Biofunction and Organization (Biology)
P19-23
Center for Nano Materials and Technology
P24
Green Device Research Center
P24
Research Center for Highly Environmental and Recyclable Polymers
P25
Research Center for Bio-Architecture
P25
Research Center for Simulation Science
P25
Cutting-edge Facilities
P26-29
Features of the Educational System
P30
Support System for International Students
P31
Facilities for Students
P32
Location
P33
Message from the
Dean of the School of Materials Science
Create Scientific and Technical Innovations by
Creating Innovative Materials!
The creation of innovative materials is expected to lead to breakthroughs in
solving the problems of modern society, such as energy problems, stagnant
growth, increase of chronic medical problems, etc. Like the roles that steel
and semiconductors served in the past, innovative materials could energize
many industries and positively affect a wide range of fields; these materials
are connected to realizing scientific and technical innovations.
Our School of Materials Science maintains advanced research facilities, such
as class 10 super-clean rooms, 800 MHz high resolution superconducting
NMR, and aberration-corrected super high resolution analysis TEM. Here,
every day top professors from around the world work with a sense of mission
to create new science and technology, and to train superior scientists and
engineers who can support the technology-based development of Japan.
Dean of the
Our School of Materials Science applies a tiered, systematic, and detailed
curriculum in education from the basics, and education for people changing
Professor
to new fields. We have also introduced a multiple-instructor system in which
Toshifumi Tsukahara
several teachers are assigned as advisors to each student. This system
enables us to accept students from various backgrounds, and to provide an environment where each
student can fully realize his or her ability. In addition, making use of our international characteristics, we
provide training in communicative competence and power of expression to address globalization and
career education. Furthermore, we have an original scholarship system, and various systems to
economically support students in studying abroad, as well as internships in domestic and foreign
companies.
The School of Materials Science at Japan Advanced Institute of Science and Technology (JAIST) hopes to
provide you with a place for new growth and rapid progress. We hope you can become a scientist or
engineer who will show society the great possibilities of materials science, and return the results of our
work to society.
Your Path Through the Two Years
Topic examples for
major research
START
April in the 1st year
Admission to JAIST
Tentative
assignment
to a laboratory
During this period, focus
on taking courses.
July in the 1st year
Assignment to a
laboratory
Begin your research
study (major and minor
researches) for a degree
after your final lab
assignment.
・Electronic devices made
from functional liquids
・DNA manipulation by
light and fabrication of
DNA computer
・Plastic made from plants
・A new type of solar cells
・Creation of
highly-functionalized
nano-particles
etc.
Minor research
An opportunity to
expand your horizons by
working on a research
topic different from your
main one.
GOAL
Feb. in the 2nd year
Submission and
Presentation of the
dissertation for the
master's degree
March in the 2nd year
Conferment of a
master's degree
Career options
・Manufacturers of
electronic components
and devices
・Companies related to
the chemical industry
・Technical engineers
in the government
and other public
organizations
etc.
1
Admissions and Expenses
Admissions
In considering applicants for admission, emphasis is placed on applicants' motivation, their intellectual
capabilities, and their skills in conducting research. JAIST admits students from Japan and abroad, including both
recent college graduates and persons who are currently employed.
For more information, please visit the website at http://www.jaist.ac.jp/english/admission/index.html
How to be a JAIST student
There are many programs, courses, and scholarships in JAIST. You may become confused and be unable to on a
suitable program for yourself. Please read the section entitled “List of Research Groups” carefully, and find a suitable
professor or a professor you are interested in, and then send an e-mail to introduce yourself including your financial
situation. All the faculty members are seeking excellent students, so they will give you advice on how to become a
JAIST student and obtain a scholarship.
Financial Aid for International Students
In order to provide financially secure graduate school life, JAIST has prepared a variety of original support systems including
benefit type scholarships (grants).
Please refer to following website. http://www.jaist.ac.jp/english/i_students/scholar.html
Cost of Living in JAIST
The cost of living at JAIST varies according to each individual's life style. However, most foreign students in JAIST
usually spend 50,000 to 70,000 JPY per month, including their accommodations.
Entrance Fee/Tuition Fee
Divison
Master’s Program
Screening Fee
Entrance Fee
30,000 JPY
282,000 JPY
Doctoral Program
Tuition Fee
267,900 JPY (semester)
535,800 JPY (year)
Entrance Fee Reduction
Those who find it difficult to pay the entrance fee because of their financial situation, and are approved as high-achieving
students, may be granted a reduction in entrance fees.
There is also an entrance fee deferment system.
Tuition Fee Reduction
Those who find it difficult to pay the tuition fee because of their financial situation, and are approved as high-achieving
students, may be granted a reduction in tuition fees.
Exemption or Reduction System in case of Disasters
Students who find it difficult to pay fees due to emergencies or disasters which occur after their application and/or entrance
to JAIST, especially emergencies involving their parents, may also be granted an exemption or reduction in entrance fees or
tuition fees.
2
Financial Support
Doctoral Research Fellowship (DRF)
The purpose of the Doctoral Research Fellowship is to admit outstanding and highly motivated students pursuing
a doctoral degree and develop their ability to carry out research as a young researcher by engaging in research
activities.
The DRF program is open for applications as follows. Students who wish to apply should bring in or mail (express
registered mail) the DRF application form to the Admissions Section by Application Deadline stated.
1
Number of Recipients
・Company sponsored applicants
・MEXT scholarship students (including prospective students)
・Foreign government scholarship students (including prospective students)
・Students who will receive a scholarship equivalent to tuition fee from JAIST
after entering the doctoral program through the internal entrance exam.
・5D program scholarship students (students who are selected for both the
5D program scholarship and the DRF must select only one of them before
enrolling in the doctoral program)
Special Type: approx. 15% of all successful applicants for the doctoral
program
Normal Type: approx. 20% of all successful applicants for the doctoral
program
2
Financial Support
The Doctoral Research Fellows receive a payment equivalent to entrance
fee (only for newly-enrolled student) and tuition fee, and moreover a
prescribed salary by engaging in research activities (employment) for a
maximum of 3 years after enrolling in the doctoral program. (It is paid as a
benefit for the last 6 months.) The hourly wage is 1,600 JPY/hour (tax
included).
Special Type: 44 hours/month work, approx.70,000 JPY/month (approx.
1,370,000 JPY/year including tuition)
Normal Type:19 hours/month work, approx. 30,000 JPY/month (approx.
890,000 JPY/year including tuition)
1. In addition to the above, an equivalent amount of entrance fee is paid
to newly-enrolled student.
2. There is a possibility of change in the working hours if the hourly wage
is revised.
3. Salary is paid based on actual hours worked.
4. Interim report, results report, and participation in business may be
requested by JAIST.
3
4
Application Deadline
Please refer to the following website.
http://www.jaist.ac.jp/english/i_students/scholar.html
5
Application Documents
The DRF application form (prescribed)
*Please download the application form the following website.
http://www.jaist.ac.jp/english/i_students/scholar.html
6
Selection Process
Selection is made based on the admission documents and the DRF
application form.
The DRF types (special or normal) will be determined during the selection
process.
7
Eligibility Requirements
Announcement of Results
The results for the DRF will be announced with the admission results in writing.
Applicants of general admissions,examination for admission on
recommendation for overseas residents, and internal doctoral program
admissions EXCEPT the following:
・Applicants of examinations for working professionals
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Contact
Student Welfare Section, Japan Advanced Institute of Science and Technology
E-mail: gakusei@jaist.ac.jp
Japanese Government (MEXT:Monbukagakusho) Scholarship
Students are accepted as "research students", and allowed the scholarship as follows:
＊Tuition: Exemption of examination, entrance and tuition fees
(If the grantee moves on to higher education as a nonregular student or fails the entrance examinations, he/she will pay for entrance examinations.)
＊Transportation: A round trip air ticket (1 round trip only)
＊Scholarship
Research student Monthly 143,000 JPY (2 years maximum)
(As of FY2014) Master’s program Monthly 144,000 JPY (The standard course term)
Doctoral program Monthly 145,000 JPY (The standard course term)
There are two types of selection processes for this scholarship
1
Embassy Recommendation
Japanese embassies select and recommend a student for the scholarship. All detailed inquiries should be addressed to the relevant Japanese government
office in your country.
2
University Recommendation
Generally students eligible for this type of scholarship should be currently enrolled in institutions that are in partnership with JAIST under an agreement on
academic exchanges, or in institutions that have research cooperation or faculty exchanges with JAIST. JAIST recommends a student to Monbukagakusho for
a scholarship on condition that the institution where a student is currently enrolled recommends him/her and JAIST has consented to accept the student.
Application Deadline: Mid January
Selection: April – June
* Application Deadline and selection period listed above are standard dates and may be subject to change according to the schedule of Monbukagakusho.
Scholarships Students Can Apply for After Entering JAIST
While most scholarships from local governments or private foundations require students to obtain recommendation from
JAIST and submit an application form via JAIST, there are some scholarships that students can apply for themselves.
Recently international students have been increasing and it is becoming very difficult to win scholarships after entering
Japanese institutes. Therefore, it is very important to secure enough financial funds to pursue your studies.
3
Material Voice
Dao Thi Ngoc Anh
Maenosono Laboratory
Yamaguchi Laboratory
My first impression about JAIST is the
access to scientific supplies. I have
everything I need for my research, from
well-equipped laboratories with innovative
technical instruments for material synthesis
and characterization, to thousands of reference books, hundreds of
free-access scientific journals and the valuable advice of outstanding
professors. We can always follow the developments in science around
the world through JAIST’s well-developed information network. In
addition, JAIST gives students chances to join great conferences in
other countries. We can present our research, listen to all the
comments and advice, discuss and exchange our experiences, learn
and enjoy culture. With these excellent conditions, all I have to do is
to enjoy research and do my best.
This area is especially quiet and peaceful with the beauty of four
seasons, which is helpful to us to focus on research and study. If you
want to relax after studying hard, it just takes 30 minutes to go
downtown and enjoy the city atmosphere of Kanazawa. I’m interested
in nature more, so I usually choose to head west to the beach or head
east to spectacular Mt. Hakusan. Life in JAIST is very comfortable. We
have nice, convenient student housing, various activities and
interesting clubs such as dance club, football club, flower
arrangement group, tea ceremony, etc. One more special thing I must
mention is international friendship of Japanese and foreign students.
That’s the most interesting and exciting experience I have. By learning
in an international environment, I’ve gained a truly global network of
peers who are also working hard to advance their own research.
Studying in Japan has been one of the
best decisions I’ve ever made in my life. I
am one of the first group of students to
enroll in the Joint-PhD. Dual Education
program. I am so proud to be one of the
members of Prof. Yamaguchi’s laboratory, in which the research
projects focus on fundamental study of polymer processing
operations, considering industrial applications. I researched the
material design of high-performance polypropylene based on
precise control of molecular orientation, and the final targets of the
polymeric materials are to be used for automobile applications.
During my stay here, I’ve gotten many opportunities from my
advisor to attend both domestic and international conferences.
Through these opportunities, I received two awards; one is the Best
Poster Presentation of Asian Workshop on Polymer Processing 2010
in Hanoi, Vietnam, and the other is ANTEC 2012 Graduate Student
Poster Competition, Ken J. Braney International Award 2012 in
Orlando, Florida, USA.
Every day as a student in JAIST, I learn not only research using
technologically advanced facilities, but also knowledge-sharing in
such a multicultural environment. This has enhanced my knowledge
of other countries and cultures, and I have met people from all over
the world. It is a good chance to grow up independently and widen
my horizons, making it not only a beautiful experience but also a
useful one. So I have to say that the two and half years I have spent
studying here have exceeded my expectations. Finally, I strongly
encourage people of all ages to come to study in JAIST, the
experience is truly worth it!!
Saumya Dabral
4
Panitha Phulkerd
Shafiul Alam
Ebitani Laboratory
Tsukahara Laboratory
I am a Dual Degree master’s student from
Delhi University, carrying out a one-year
research project at JAIST. The reason I
decided to come to JAIST was the
positive response and praises given to
JAIST by previous students from Delhi, for its state-of-the-art
research facilities and equipments which help develop a researcher’s
mind. Here at JAIST we have access to a variety of analytical
instruments, which makes research a lot easier and more fun.
JAIST has a large number of international students, so we have a
very interesting multicultural environment. Also, it provides us
ample opportunities for interacting with different people and
learning about various cultures. In our lab itself we have students
from Japan, India, China, Thailand and Vietnam, and this makes
working in the lab very enjoyable.
Living at JAIST has been a great experience both in terms of
research and extracurricular activities. JAIST is surrounded by
splendid natural beauty, which inspires us to explore the nearby
surrounding areas. We usually borrow bicycles from the school itself
(since JAIST has a large number of bicycles for students), and during
the weekend we all go together to explore the surroundings of
JAIST. Also, the JAIST shuttle bus links us to various stations, so we
can easily travel to different regions of Japan and enjoy sightseeing.
Overall, coming to JAIST has been a very pleasant experience for
me. It not only helped me mature as a researcher, but also helped
me learn about different cultures. If given a chance, I would like to
come here again for a doctoral degree.
I am a doctoral student in Tsukahara
Lab. on Molecular Biology which gives
me an opportunity to explore the
chemistry of life and the medical
sciences. There were multiple factors
that guided me to decide to become a proud member of the
JAIST family. Most importantly, JAIST offers a friendly but
serious atmosphere for high quality research, which meets my
expectations for depth and breadth of education and life quality.
JAIST is a hub of multiple cultures. Approximately 25% of
students are foreign students. After coming here, I found
multiple cultures are living together in a highly harmonic manner,
which gives me the sense of globalization of cultures. Coming
from a Muslim culture, I did not find any difficulties to follow my
culture. This gives me mental satisfaction, and helps me to
concentrate on my research. My professor is very kind, and
careful in choosing foods for a lab party or any other occasions.
Moreover, in JAIST, we have a cultural organization, the JAIST
Muslim Circle, JMC in which, being a member, anyone can learn
the depth of Muslim culture along with other different cultures.
JAIST, research, faculty, and the students have surpassed all my
expectations. I expected new friends, but now I have immense
feelings of satisfaction, that I have achieved a new family. I
expected excellence in research, and am consistently impressed
both with the enthusiasm and energy of my professor to nurture
me, and with the state-of the art lab facilities. I have noticed that
JAIST has a progressive attitude and constant desire to improve.
Patrick Degenaar,
Ph.D.
Reader in Biomedical Electronics
School of Electrical and
Electronic Engineering
University of Newcastle upon Tyne
Greetings to all at JAIST from the UK. I am Dr. Patrick
Degenaar, a Reader (Associate Prof.) in Biomedical
Electronics. Between 1997 and 2001 I was a Monbusho
scholar and PhD student in the School of Materials
Science at JAIST, studying under Prof. Tamiya. I
researched into artificial neuron networks.
My interest in coming to JAIST was to access the high
tech facilities which allowed my PhD to be a success. My
professor was very supportive and built a collaborative
environment within his lab. This allowed me to do joint
research projects with Tokyo University, eventually
leading to my patent and key research papers. Prior to
my PhD, I was also able to learn the Japanese language
through a 6 month language program at Kanazawa
University organised by the Monbusho scheme. Though
after ten years, I’m beginning to forget, it is nice to have
a basic conversation with Japanese researchers at
conferences.
Antonio Caraballo,
Ph.D.
Technical Specialist
Pipelines Integrity
Management Unit, Saudi Aramco
I was one of five students from Colombia selected by the
Japanese Government for a Monbukagakusho
scholarship. I decided to carry out my graduate studies
at JAIST, not only because of the reputation of the school
and its ranking, but also because of the high quality of
the faculty, its international atmosphere, and the support
offered to its international research students. I carried out
graduate studies under the guidance of Professor
Kawakami, who since then has become a life mentor and
a very close friend.
After graduating from JAIST, I moved to the United
Kingdom and worked in different engineering positions
for several companies within the Oil and Gas industry,
including operators and consultancy houses. In my
current position, I am a Pipeline Technical Specialist for
Saudi Aramco, the world’s biggest oil producer.
I am certain that JAIST provided me with the vital skills to
achieve my career and personal goals, as well as the
On a personal level, I have some fond memories of skiing
in Ichirino, camping on Mount Hakusan, and cycling over
the mountains to Gifu and Toyama, and attending the
various matsuri festivals around the prefectures. In
Ishikawa, each season is pronounced and allows it’ s own
special activities. Kanazawa city is very beautiful and I’ m
keen to return one day to visit with my family. Perhaps
even climb Hakusan once more with my son.
When I returned to Europe, I found there was a great
respect for having studied my PhD in Japan. It allowed
me to get a post-doctoral position, and later a
lectureship position, at Imperial College in London.
However, I learned to really appreciate the countryside at
JAIST and decided to move from London. I now have my
own large laboratory in Newcastle, UK, where I bring
together optoelectronics and neuroscience research
(http://research.ncl.ac.uk/neuroprosthesis/) and lead a
European project (www.optoneuro.eu) on retinal
prosthesis.
adaptability and abilities to work as part of a team with
people from different cultures and backgrounds. At
JAIST I experienced on a daily basis the values that have
made Japan a success around the world, values such as
hard work, discipline, determination, perseverance,
integrity and partnership.
During my time as a graduate student in Japan, I joined
in traditional activities such as Aikido and Karate. I also
travelled extensively through the country, and explored
the beautiful contrasts between the coastal and
mountainous areas. JAIST provided me with an enriching
environment in which I could integrate, and learn about
Japan’s history, culture and values.
All in all, I believe that the education and the personal
experiences I acquired as a postgraduate student at
JAIST have instilled in me the qualities required to
develop an international career, and to improve my
cross-cultural skills, which are critical in the global
business environment, but which are often overlooked.
5
Material Voice
Anis Haque,
Ph.D.
Associate Director of Students
Department of Electrical and
Computer Engineering
University of Calgary
I received my doctoral degree in Materials Science from
JAIST in 2002, and currently I am a faculty member with
the Electrical and Computer Engineering Department at
the University of Calgary in Canada. I love teaching and
enjoy doing research.
My dream to do research in magnetoelectronics was
seeded while I was studying at the University of
Cambridge in England. This bloomed at JAIST under
Professor Hidenobu Hori’s tutelage. The School of
Materials Science at JAIST has outstanding research
facilities, including a world-class cleanroom with nanoscale
device fabrication and in-situ characterization facilities. I
did not know Japanese language before going to JAIST in
1998, but I had no difficulties in my study. Higher-level
courses were offered in English. The students in the lab
were so friendly that everyone was willing to help me
make a smooth transition to a new system and culture,
Hak Soo Choi,
Ph.D.
Assistant Professor of Medicine
Beth Israel Deaconess Medical Center,
Harvard Medical School
I am a faculty member of the Beth Israel Deaconess
Medical Center and Harvard Medical School. I am a
graduate of the Polymer-Nano Science Program at
Chonbuk National University, South Korea and earned my
Ph.D. degree in biomaterials and drug delivery systems
from JAIST. In 2005, I extended my research into
molecular imaging and tumor targeting, and joined the
Center for Molecular Imaging at Beth Israel Deaconess
Medical Center in Boston, Massachusetts. I was promoted
to Instructor in Medicine in 2008, and Assistant Professor
of Medicine in 2011 at Harvard Medical School. My
laboratory focuses on the development of new diagnostic
agents to solve important problems in oncology and
clinical medicine, with an emphasis on in vivo imaging and
tumor-specific contrast agent development. A theme of
study over the last five years has been the interaction of
nanoparticles with the body, and the establishment of
design parameters to achieve adequate biodistribution
and clearance for tumor imaging.
6
and the institute provided me a fulltime tutor for this.
After completing my two-year postdoctoral research at
Osaka University, I left Japan in 2004. Some of my best
Japanese friends at JAIST came to Osaka and had a
farewell party for me.
JAIST is located in the Mount Hakusan area, and within 20
minutes drive from the Japan Sea. I loved the spectacular
scenic beauty of Hakusan. The mountain is a paradise for
hiking, skiing, fishing, camping, gliding, and so on. The
people in the community around JAIST are very friendly to
the foreign students, and they are respectful to foreign
culture and religion. I regularly participated in various
cultural and social events in the community.
The School of Materials Science at JAIST is a perfect place
for postgraduate study and I feel proud that I had this
opportunity. I still miss JAIST, and I wish I could go back.
My research is focused on the development of novel
agents for cancer diagnosis, staging, and treatment.
Targeted nanoparticles, which are capable of carrying a
large “payload” that can be used for disease diagnosis
and treatment, are especially important Our recent
studies have focused on defining the chemical and
physiological properties required for nanoparticles to be
cleared effectively.
Along a similar theme, we have been systematically
probing the relationships among diagnostic agent
h y d r o d y n a m i c d i a m e t e r, s h a p e , c h a r g e , a n d
hydrophobicity on in vivo biodistribution and clearance.
Armed with the ability to a priori engineer small
molecules, my final area of interest is the discovery of lead
compounds that bind specifically to living cancer cells. I
have supervised the Robotic Chemistry Group at the
BIDMC Center for Molecular Imaging, which is capable of
quickly screening thousands of small molecules against
dozens of types of living cancer cells.
CMI Retreat 2010, Beth Israel Deaconess Medical Center, Harvard Medical School
Mizutani Group
Tomitori Group
Professor Goro Mizutani
Assistant Professor Hien Thi Thu Khuat
Professor Masahiko Tomitori
Assistant Professor Akira Sasahara
E-mail: mizutani@jaist.ac.jp
E-mail: tomitori@jaist.ac.jp
Symmetry-Sensitive Nonlinear
Optical Microscopy
Nanoscale Surface Science
Nanoprobe Technology
Outline:
Outline:
What images do you expect, if you can map the information of molecular shapes? Such imaging can be done by detecting optical sum
frequency generation (SFG) or second harmonic generation (SHG)
from materials. We develop SFG and SHG microscopes for detecting non-centrosymmetric species in biomaterials and on surfaces. In
figures (a) and (b) below, you see visible and SHG images of a part
of a water plant, respectively. Starch is judged to be localized only
in the future seed in image (b) and the relevant polysaccharide
structures can be analyzed in the SFG images resonant with molecular vibrations. SFG microscopy has also been shown to be the only
method to visualize non-destructively the hydrogen distribution on
a silicon surface.
We aim at the new frontier of surface science at the nanoscale
through development of novel instrumentation based on scanning
probe microscopy/spectroscopy (SPM/SPS) techniques. SPM can
depict images of sample surfaces at atomic resolution using a sharpened tip, which scans the surfaces while maintaining constant tunneling current or force between the tip and the surfaces. Quantum
mechanical behaviors can be interestingly revealed by these methods. Our targets include exotic materials such as semiconductors
and oxides. We measure the properties of materials, including various reactions and interactions, in order to describe them accurately
for future usage in nanomechanical electronic devices.
Ge dots on a Si tip
Recent selected publications:
“Absolute second order nonlinear susceptibility of Pt nanowire arrays on MgO
faceted substrates with various cross-sectional shapes”, Yoichi Ogata and Goro
Mizutani, Applied Physics Letters 103(9), 093107/1-4 (2013)
“Selective observation of local carrier dynamics at step bunches on vicinal TiO2
(110) by time-resolved pump-probe second harmonic generation method”, H.
Takahashi, Y. Miyauchi, and G. Mizutani, Physical Review B86(4), 045447/1-13
(2012).
“Optical second harmonic generation from Pt nanowires with boomerang-like
cross-sectional shapes”, Y. Ogata, N. A. Tuan, Y. Miyauchi, and G. Mizutani, Jounal
of Applied Physics 110(4), 044301 (2011).
“Discovery of deep and shallow trap states from step structures of rutile TiO2
vicinal surfaces by second harmonic and sum frequency generation spectroscopy”,
H. Takahashi, R. Watanabe, Y. Miyauchi, and G. Mizutani, Journal of Chemical
Physics 134(15), 154704/1-13 (2011).
“Optical second harmonic generation at heterojunction interfaces of a
molybdenum trioxide layer and an organic layer”, A. B. El Basaty, Y. Miyauchi, G.
Mizutani, T. Matsushima, and H. Murata, , Applied Physics Letters 97, 193302
(2010).
“XPS and STM Study of Nb-doped TiO2 (110)-(1×1) surfaces”, A. Sasahara and M.
Tomitori, J. Phys. Chem. C 117 (2013) 17680.
“Lateral distribution of Li atoms at the initial stage of adsorption on TiO2(110)
surface”, H. Tatsumi, A. Sasahara and M. Tomitori, J. Phys. Chem. C 116 (2012)
13688.
“Local interaction imaging by SiGe quantum dot probe”, Y. Jeong, M. Hirade, R.
Kokawa, H. Yamada, K. Kobayashi, N. Oyabu, T. Arai, A. Sasahara and M. Tomitori, Current Appl. Phys. 12 (2012) 581.
“Atomic scale analysis of ultrathin SiO2 films prepared on TiO2(100) surfaces”, A.
Sasahara, C.L. Pang and M. Tomitori, J. Phys. Chem. C 114 (2010) 20189.
“Adsorption state of 4,4”-diamino-p-terphenyl through an amino group bound to
Si(111)-7x7 surface examined by X-ray photoelectron spectroscopy and scanning
tunneling microscopy”, T. Nishimura, A. Itabashi, A. Sasahara, H. Murata, T. Arai
and M. Tomitori, J. Phys. Chem. C 114 (2010) 11109.
Recent research funds
The Ogasawara Foundation for Research and Development, 2004, G. Mizutani, 200,000
JPY
The Ogasawara Foundation for Research and Development, 2005, G. Mizutani, 100,000
JPY
JST, CREST, 2006-2010, G. Mizutani, 187,387,000 JPY
Grant-in-Aid for Scientific Research (C), MEXT, 2011-2014, G. Mizutani, 7,000,000 JPY
The Ogasawara Foundation for Research and Development, 2012, G Mizutani, 170,000 JPY
Grant-in-Aid for Challenging Exploratory Research, MEXT, 2014-2016, M.Tomitori, 3,900,000 JPY
Grant-in-Aid for Challenging Exploratory Research, MEXT, 2014-2015, A. Sasahara, 3,900,000 JPY
Grant-in-Aid for Scientific Research (A), MEXT, 2012-2015, M. Tomitori, 44,980,000 JPY
Grant-in-Aid for Challenging Exploratory Research, MEXT, 2010-2012, M.Tomitori, 3,770,000 JPY
Grant-in-Aid for Scientific Research (A), MEXT, 2008-2011, M. Tomitori, 49,270,000 JPY
Grand-in-Aid for Young Scientists (A), MEXT, 2009-2011, A. Sasahara, 26,780,000 JPY
7
Takamura (Yukiko) Group
Suzuki Group
Associate Professor Yukiko Yamada-Takamura
Assistant Professor Antoine Fleurence
Professor Toshi-kazu Suzuki
E-mail: yukikoyt@jaist.ac.jp
E-mail: tosikazu@jaist.ac.jp
Development of Nanomaterials
Based on the Understanding of
Surfaces and Interfaces
Compound Semiconductor
Materials and Devices
for Ultra-high-speed Electronics
Outline:
Outline:
Modern industry is founded on thin film materials technologies,
ranging from protective coatings to electronic devices, and in order
to improve their performance, controlling film-substrate interfaces is
critical. The surfaces and interfaces become even more important in
the growth of nanomaterials and their properties, since the bulk
part is reduced and the surfaces and interfaces become dominant.
Our aim is to develop new nanomaterials based on the atomistic
understanding of surfaces and interfaces, with the support of
advanced microscopies, such as scanning tunneling microscopy and
transmission electron microscopy. The hottest topic in our group,
right now, is the study of Si-version graphene, "silicene" , which is
an ultimate Si-made nanomaterial with single-atom thickness. We
found this new two-dimensional material while trying to understand
the surface structure of diboride thin films grown on Si wafers. "Silicene" is the fruit of successful collaboration with the photoelectron
spectroscopy group and the first-principles calculation group in
JAIST.
For further progress in future ultra-high-speed electronics, including
optoelectronics, development of new compound semiconductor
devices is important. In our laboratory, we study compound semiconductor materials and their device physics for new electronics,
based on narrow-gap semiconductors such as InAs, and also widegap semiconductors such as GaN. In particular, we investigate the
heterogeneous integration technologies of these compound semiconductor devices in combination with different materials, which will
open up superior or novel functionalities in electronics, leading to
"More than Moore" technological diversification.
“Microscopic origin of the π states in epitaxial silicene”, A. Fleurence, Y. Yoshida,
C.-C. Lee, T. Ozaki, Y. Yamada-Takamura, and Y. Hasegawa, Appl. Phys. Lett. 104
(2014) 021605.
“First-principles study on competing phases of silicene: Effect of substrate and
strain”, C.-C. Lee, A. Fleurence, R. Friedlein, Y. Yamada-Takamura, and T. Ozaki,
Phys. Rev. B 88 (2013) 165404.
“Mechanisms of parasitic crystallites formation in ZrB2(0001) buffer layer grown on
Si(111)”, A. Fleurence, W. Zhang, C. Hubault, and Y. Yamada-Takamura, Appl.
Surf. Sci. 284 (2013) 432-437.
“Tuning of silicene-substrate interactions with potassium adsorption”, R. Friedlein,
A. Fleurence, J. T. Sadowski, and Y. Yamada-Takamura, Appl. Phys. Lett. 102
(2013) 221603.
“Experimental evidence for epitaxial silicene on diboride thin films”, A. Fleurence,
R. Friedlein, T. Ozaki, H. Kawai, Y. Wang, and Y. Yamada-Takamura, Phys. Rev.
Lett. 108 (2012) 245501.
“Surface electronic structure of ZrB2 buffer layers for GaN growth on Si wafers”, Y.
Yamada-Takamura, F. Bussolotti, A. Fleurence, S. Bera, and R. Friedlein, Appl.
Phys. Lett. 97 (2010) 073109.
“AlGaN-GaN metal-insulator-semiconductor high- electron-mobility transistors
with very high-k oxynitride TaOxNy gate dielectric”, T. Sato, J. Okayasu, M.
Takikawa, and T. Suzuki, IEEE Electron Dev. Lett. 34 (2013) 375.
“Fabrication and characterization of BN/AlGaN/GaN metal-insulatorsemiconductor heterojunction field-effect transistors with sputtering-deposited
BN gate dielectric”，T. Q. Nguyen, H.-A. Shih, M. Kudo, and T. Suzuki，Phys. Status
Solidi C 10 (2013) 1401.
“Analysis of AlN/AlGaN/GaN metal-insulatorsemiconductor structure by using
capacitance- frequency-temperature mapping”, H.-A. Shih, M. Kudo, and T.
Suzuki, Appl. Phys. Lett. 101 (2012) 043501.
“Electron distribution and scattering in InAs films on low-k flexible substrates”, C.
T. Nguyen, H.-A. Shih, M. Akabori, and T. Suzuki, Appl. Phys. Lett. 100 (2012)
232103.
“Carrier recombination lifetime in InAs thin films bonded on low-k flexible
substrates”, T. Suzuki, H. Takita, C. T. Nguyen, and K. Iiyama, AIP Advances 2
(2012) 042105.
Grant-in-Aid for Scientific Research (A), JSPS, 2014-2017, “Interface control of epitaxial silicene”,
Y. Yamada-Takamura, 40,820,000 JPY
Grant-in-Aid for Young Scientists (B), JSPS, 2014-2015, “Formation mechanism of epitaxial
silicene”, A. Fleurence, 4,160,000 JPY
Funding Program for Next Generation World-Leading Researchers, JSPS, 2010-2013, “Surface
and interface studies of epitaxial diboride thin films for integration with nitride semiconductors”,
Y. Yamada-Takamura, 145,600,000 JPY
Grant-in-Aid for Scientific Research (A), MEXT, 2014-2016, T. Suzuki (partial), 10,600,000 JPY.
Joint Research with Sony Corporation, 2011-2012, Research on characterization of GaAs
MISHEMTs, T. Suzuki, 4,000,000 JPY.
Joint Research with Advantest Laboratories Limited, 2010-2013, Research on characterization of
compound semiconductors, T. Suzuki, 4,800,000 JPY.
Joint Research with Horiba Limited, 2007-2011, Research on device applications of latticemismatched growth, T. Suzuki, 4,400,000 JPY.
8
Mizuta Group
Horita Group
Professor Hiroshi Mizuta
Assistant Professor Manoharan Muruganathan
Associate Professor Susumu Horita
E-mail: mizuta@jaist.ac.jp
E-mail: horita@jaist.ac.jp
Hybrid Nanoelectronics and Atomic-scale
Devices - Emerging Nanotechnologies for
‘More-than-Moore’ and ‘Beyond CMOS’ Era
Science and Technology of
Low-temperature Thin Film Growth for
Electron Devices
Outline:
Outline:
Atomscale materials such as graphene (single carbon layer) and
ultrathin SOI (silicon-on-insulator) are used to fabricate ultrasmall
transistors, single-molecular sensors and NEMS, and the extreme
characteristics of these materials are unveiled. Novel hybrid functional devices - abrupt switch, nonvolatile memory and nanosensor are developed by co-integrating NEMS and conventional devices
such as MOSFET and single-electron transistors. Single-electron
spin-based quantum information technology is also developed by
integrating multiple quantum dots, a nano magnet, a nano
electron-spin-resonance (EMR) device and a readout on Si and graphene platform with a long spin decoherence time.
Our group researches low-temperature crystallization of Si film on a
glass or plastic substrate, and low-temperature formation of an Si
oxide (SiO2) film for thin-film transistors. These techniques for lowtemperature film growth are desirable for energy saving, resource
conservation, and preventing global warming in the future. We try
to make Si films crystallize on glass substrates at less than 300 ºC by
using a seed layer of polycrystalline YSZ (yttria-stabilized zirconia).
SiO2 films are deposited by thermal reaction between
environmentally-safe silicone oil and ozone gas at 200 ºC. We investigate and discuss film growth and material properties scientifically,
which will answer your research questions.
Fig. 1. TEM image around interface between
crystallized Si film and YSZ layer. The Si film
o
was deposited at 430 C by vacuum evaporation. Now, we are trying tolower Si Crystallization Temperature.
Fig. 2. SEM image of SiO 2 film deposited
o
by silicone oil and ozone gas at 200 C. The
film covers the whole trench structures with
200-nm-width and 1300-nm-depth.
“Low pull-in voltage graphene electromechanical switch fabricated with a polymer
sacrificial layer “, J. Sun, W. Wang, Manoharan M. and H. Mizuta, in press for Appl.
Phys. Lett. (2014)
“Raman study of damage extent in graphene nanostructures carved by high
energy ion beam“, S. Hang, Z. Moktadir and H. Mizuta, Carbon 72, 233-241 (2014)
“Point defect induced transport bandgap widening in the downscaled armchair
graphene nanoribbon device” , Manoharan M. and H. Mizuta, Carbon 64, 416
(2013)
“VLSI Compatible parallel fabrication of scalable few electron Silicon Quantum
Dots “, Y. P. Lin, J. I. Perez-Barraza, M. K. Husain, F. M. Alkhalil, N. Lambert, D. A.
Williams, A. J. Ferguson, H. M. H. Chong and H. Mizuta, IEEE Trans.
Nanotechnology 12, 897 (2013)
“Magnetoresistance in inhomogeneous graphene/meral hybrids “, Z. Moktadir and
H. Mizuta, J. Appl. Phys. 113, 083907 (2013)
“Electron-tunneling operation of single-donor-atom transistors at elevated
temperatures “, E. Hamid, D. Moraru, Y. Kuzuya, T. Mizuno, Le The Anh, H. Mizuta,
and M. Tabe, Phys. Rev. B 87, 085420 (2013)
“Effect of Crystallization-Induction Layer of Yttria-Stabilized Zirconia on Solid State
Crystallization of an Amorphous Si Film” , S. Horita and T. Akahori, J. Appl. Phys.
53 (2014) 030303.
“Raman Spectra Analysis of Si Films Solid-Phase-Crystallized on Glass Substrates
by Pulse Laser with Crystallization-Induction Layers of Yttria-Stabilized Zirconia” ,
M. T. K. Lien and S. Horita, Jpn. J. Appl. Phys. 53 (2014) 03CB01.
“Low-temperature crystallization of silicon films directly deposited on glass
substrates covered with yttria-stabilized zirconia layers” , S. Horita and H. Sukreen,
Jpn. J. Appl. Phys. 49 (2010) 105801.
“Disturb-free writing operation for ferroelectric gate field-effect transistor
memories with intermediate electrodes” , S. Horita and B. N. Q. Trinh, IEEE Trans.
Electron Devices 56 (2009) 3090.
“Low temperature deposition and crystallization of silicon film on an HF-etched
polycrystalline yttria-stabilized zirconia layer rinsed with ethanol solution“, S. Horita
and H. Sukreen, Appl. Phys. Express 2 (2009) 04120.
“Low-temperature deposition of silicon oxide film from the reaction of silicone oil
vapor and ozone gas” , S. Horita, K. Toriyabe, and K. Nishioka, Jpn. J. Appl. Phys.
48 (2009) 035501.
Grant-in-Aid for Scientific Research(S), 2013-2018, Development of graphene NEMS hybrid
functional devices for autonomous and ultrasensitive integrated sensors, Hiroshi Mizuta,
124,800,000 JPY
Grant-in-Aid for Scientific Research(S), 2011-2016, Development of dopant atom devices based
on silicon nanostructures, Michiharu Tabe (Shizuoka Univ.), 18,980,000 JPY
Grant-in-Aid for Scientific Research(B), 2010-2013, Atom-scale design and characterization
technique for single-dopant controlled silicon nanoelectronics, Hiroshi Mizuta, 19,500,000 JPY
The Mitani Foundation for Research and Development, 2014, S. Horita, 1.000,000 JPY
Grant-in-Aid for Scientific Research (C), JSPS, 2009-2011, S. Horita, 4,680,000 JPY
JST, Research Seeds Growth, 2006, S. Horita, 2,000,000 JPY
JST, Research Seeds Growth, 2005, S. Horita, 2,000,000 JPY
9
Tokumitsu Group
Shimoda Group
Professor Eisuke Tokumitsu
Professor Tatsuya Shimoda
Assistant Professor Takashi Masuda
E-mail: e-toku@jaist.ac.jp
E-mail: tshimoda@jaist.ac.jp
Functional Oxide Devices and
Their Fabrication Technologies
Direct Formation of Electronic
Devices Using Functional Solutions
Outline:
Outline:
Since metal oxides have a variety of electrical properties, we can
fabricate various components including electrodes and insulators,
using oxides and ferroelectric and resistive switching materials. In
our group, novel functional electron devices using oxides and their
fabrication technologies have been investigated. We have pointed
out that the ferroelectric gate insulator can control large charge
density and nonvolatile memory function, and we have developed
transparent and flexible ferroelectric-gate transistors (FGTs) using
oxide channels. In addition, we have successfully fabricated all layers
of the FGT, electrodes, gate insulator and channel, using the solution deposition process.
We have been investigating solution processes for applications in
electronic devices, such as thin film transistors, solar cells, etcetera.
Several classes of functional liquid materials are used, which include
organic materials, metal oxides, liquid silicon (including its derivatives) and metal nano-particles dispersed in solvent. As for the fabrication process, ink-jet, nano-imprint and self-assembling methods
are used both separately and in combination. To control the solution process for making a good device, it is important to study wettability, spreading and micro-patterning behaviors, phenomena
during solvent evaporation and so on. Therefore, understanding the
intermolecular and surface forces in a specified geometry and material condition is the essential part of our scientific activity.
“Unipolar behavior in grapheme-channel field-effect-transistors with n-type doped
SiC source/drain regions”, Y. Nagahisa, Y. Harada, and E. Tokumitsu, Appl. Phys.
Lett., 103, (2013) 223503.
“A 60 nm channel length ferroelectric-gate field-effect transistor capable of fast
switching and multilevel programming”, Y. Kaneko, Y. Nishitani, M. Ueda, E.
Tokumitsu, and E. Fujii, Appl. Phys. Lett. 99 (2011) 182902.
“Multiagent strategic interaction based on a game theoretical approach to
polarization reversal in ferroelectric capacitors”, D. Ricinschi and E. Tokumitsu, J.
Adv. Comput. Intell. Informat. 7 (2011) 806.
“Low-voltage operation of ferroelectric gate thin film transistors using indium
gallium zinc oxide-channel and ferroelectric polymer poly(vinylidene
fluoridetrifluoroethylene)”, Gwang-Geun Lee, Y. Fujisaki, H. Ishiwara, and E.
Tokumitsu, Appl. Phys. Exp. 4 (2011) 091103.
“The flexible non-volatile memory devices using oxide semiconductors and
ferroelectric polymer poly(vinylidene fluoride-trifluoroethylene)”, G.-G. Lee, E.
Tokumitsu, S.-M. Yoon, Y. Fujisaki, J.-W. Yoon, and H. Ishiwara, Appl. Phys. Lett.
99 (2011) 012901.
“Rheology printing for metal-oxide patterns and devices“, T. Kaneda, D. Hirose, T.
Miyasako, P. T. Tue, Y. Murakami, S. Kohara, J. Li, T. Mitani, E. Tokumitsu, and T.
Shimoda, J. Mater. Chem. C 2 (2014) 40.
“Liquid silicon and its application for electronics“, T. Shimoda, and T. Masuda, Jpn.
J. Appl. Phys. 53 (2014) 02BA01.
“Amorphous Silicon Carbide Films Prepared Using Vaporized Silicon Ink“, T.
Masuda, Z. Shen, H. Takagishi, K. Ohdaira, and T. Shimoda, Jpn. J. Appl. Phys. 53
(2014) 031304.
“Fabrication of a Solution-Processed Hydrogenated Amorphous Silicon SingleJunction Solar Cell”, T. Masuda, N. Sotani, H. Hamada, Y. Matsuki, and T.
Shimoda, Appl. Phys. Lett. 100 (2012) 253908.
“Selected Deposition of High-Quality Aluminum Film by Liquid Process”, Z. Shen,
Y. Matsuki and T. Shimoda, J. Am. Chem. Soc. 2012, 134, 8034−8037.
“Spectral parameters and Hamaker constants of silicon hydride compounds and
organic solvents”, T. Masuda, Y. Matsuki, and T. Shimoda, J. Colloid Interface. Sci.
340 (2009) 298.
Grant-in-Aid for Scientific Research (B), JSPS, 2012-2014, E. Tokumitsu, 14,000,000 JPY
Grant-in-Aid for Exploratory Research, JSPS, 2012-2013, E. Tokumitsu, 3,100,000 JPY
Grant-in-Aid for Scientific Research (B), JSPS, 2009-2011, E. Tokumitsu, 13,600,000 JPY
Grant-in-Aid for Exploratory Research, JSPS, 2005-2006, E. Tokumitsu, 2,700,000 JPY
Grant-in-Aid for Exploratory Research, JSPS, 2004, E. Tokumitsu, 3,600,000 JPY
10
JST-ERATO (Shimoda Nano-Liquid Process Project), JST, 2006-2011, T. Shimoda,
1,780,000,000 JPY
JST-ERATO (Shimoda Nano-Liquid Process Project, extended), JST, 2012-2014, T.
Shimoda, 294,000,000 JPY
JST-Advanced Low Carbon Technology Research and Development Program, 2011-2013,
Thin film solar cell by solution process, T. Shimoda, 260,000,000 JPY
Iwasaki Group
Murata Group
Professor Hideo Iwasaki
Professor Hideyuki Murata
Assistant Professor Heisuke Sakai
E-mail: hideo@jaist.ac.jp
E-mail: murata-h@jaist.ac.jp
1mm
Creation and Physical Properties of
Functional Materials
Organic Electronic Devices - An Interdisciplinary Research Field
that Integrates Chemistry and Physics
Outline:
Outline:
Preservation of energy source and natural environment are the
world wide serious problems. We focus on superconductivity and
thermoelectricity. Especially, we have completed the development
of special equipment related to evaluation of the thermoelectric
figure of merit, ZT which is based on the voltage measurements in
thermally isolated condition of the sample. This was successfully
applied to the evaluation in microscopic thermoelectric devices.
Right now, we are interested in nanoscopic thermoelectricity
because of its high thermoelectric performance, where the equipment with high measurement accuracy mentioned above would be
inevitably required in new material creation.
Research on the properties of organic materials is one of the fields
in which Japan has been leading the world. Organic electroluminescent (EL) displays have been commercialized in Japan, and the
implications and significance of our success in organic electronic
devices have been widely recognized. At Murata Laboratory we are
developing organic electronic devices, which are expected to play
an important role in the future. Our research interests involve synthesis of new materials and development of novel organic devices
such as organic light-emitting diodes (OLEDs), organic solar cells
(OSCs) and organic memory transistors (OMTs).
Evaluation of the figure of merit, ZT by the voltage measurements
Equivalent
Laboratory made equipment
Vac : ac voltage
Vdc : dc voltage
“Thermoelectric Properties of (Bi1-xSbx)2S3 with Orthormbic Structure”, Y Kawamoto and H. Iwasaki, J. Electronic Materials (2014) DOI: 10/s 11664 -013-2742-5.
“Development of a Measurement System for the Figure of Merit in the HighTemperature Region, H. Iwasaki, T. Yamamoto, H. Kim and G. Nakamoto”, J.
Electronic Materials 42 1840 (2013).
“Phase Transition of Josephson Vortices Under High Magnetic Fields up to 30T in
Heavily Overdoped YBa 2 Cu 3 O 7−δ Single Crystals”, T. Naito, H. Iwasaki, T.
Nishizaki and N. Kobayasi, J. Low Temp. Phys. 159 168 (2010)
“Thermal Conductivity and Seebeck Coefficient of 12Cao7Al2O3 Electride with a
Cage Structure”, S. W. Kim, R. Tarumi, H. Iwasaki, H. Ohta, M. Hirano, and H.
Hosono, Rhys. Rev. B80 075201-1 (2009)
“Nanostructured Poly(3- hexylthiophene-2,5-diyl) Films with Tunable Dimensions
through Self-Assembly with Polystyrene,V. Vohra, O. Notoya, T. Huang, M.
Yamaguchi, H. Murata, Polymer, 55, 2213-2219 (2014)
“Uniaxial macroscopic alignment of conjugated polymer systems by directional
crystallization during blade coating “B. Dörling, V. Vohra, T. T. Dao, M. Garriga, H.
Murata and M. Campoy-Quiles, J. Mater. Chem.C, 2, 3303- 3310 (2014).
“Horizontally oriented molecular thin films for application in organic solar cells’, T.
Matsushima, H. Matsuo, T. Yamamoto, A. Nakao, H. Murata, Sol. Energy Mater.
Sol. Cells, 123, 81-91 (2014).
“Controllable threshold voltage of a pentacene field-effect transistor based on a
double-dielectric Structure”, T. T. Dao, T. Matsushima, R. Friedlein, H. Murata,
Org. Electron., 14, 2007-2013 (2013)
“Improved initial drop in operational lifetime of blue phosphorescent organic light
emitting device fabricated under ultra high vacuum condition”, H. Yamamoto, J.
Brooks, M. S. Weaver and J. J. Brown, T. Murakami and H. Murata, Appl. Phys.
Lett., 99, 033301 (2011).
Research Fund with Quantum Design Japan Ltd., 2012, H. Iwasaki 1,500,000 JPY
Joint Research Fund with Komatsu Ltd. 2011, H. Iwasaki 750,000 JPY
Joint Research Fund with Komatsu Ltd. 2010, H. Iwasaki 750,000 JPY
CEREBA, NEDO, 2013-2014, H. Murata, 4,000,000 JPY
JSPS-FIRST (OPERA), 2009-2013, H. Murata, 50,000,000 JPY
Grants-in-Aid for Scientific Research on Innovative Areas, JSPS, 2008-2012, H. Murata,
24,200,000 JPY
Grants-in-Aid for Scientific Research (A), JSPS, 2008-2011, H. Murata, 38,856,000 JPY
Green IT Project, NEDO, 2008-2009, H. Murata, 45,151,000 JPY
11
Ohdaira Group
Koyano Group
Associate Professor Keisuke Ohdaira
Associate Professor Mikio Koyano
E-mail: ohdaira@jaist.ac.jp
E-mail: koyano@jaist.ac.jp
Development of Si-based
Next-generation Solar Cells Through
Novel Process Technologies
Thermoelectric Conversion and
Condensed-Matter Physics
Outline:
Outline:
Solar cells fabricated using silicon (Si), which is abundant on earth,
occupy a high share of the present world market, and will also be the
mainstream of photovoltaic technology in the future. However,
further cost reduction and efficiency improvement are required for
our Si-based solar cells, and we need another technological breakthrough. In this lab, we focus our attention on recent process technologies, such as flash lamp annealing (FLA) for the rapid formation
of polycrystalline Si films, and catalytic chemical vapor deposition
(Cat- CVD) for excellent surface passivation on crystalline silicon. Also,
in cooperation with Prof. Shimoda, we are using liquid Si for very
cost-effective production of amorphous Si files for use in solar cells.
Thermoelectric conversion technology has been attracting a great
deal of attention as a means to solve current energy problems. This
technology enables direct alternating conversion between poor
quality thermal energy and high-quality electric energy. We are identifying various properties of thermoelectric materials and their
relevant compounds, and developing new nano-composites using
advanced equipment and innovative methods. Especially, our laboratory has developed new high-temperature Pb&Te-free thermoelectric materials with complex structures. We have recently been
conducting further research on these materials, and developing
Bi-Sb-based low-temperature thermoelectric materials.
Thermoelectric cooling
Thermoelectric generation
“A Method to evaluate explosive crystallization velocity of amorphous silicon films
during flash lamp annealing”, K. Ohdaira, Can. J. Phys. 92 (2014) 718.
“Deposition of moisture barrier films by Cat-CVD using hexamethyldisilazane”, K.
Ohdaira and H. Matsumura, Jpn. J. Appl. Phys. 53 (2014) 05FM03.
“Effect of annealing and hydrogen radical treatment on the structure of solutionprocessed hydrogenated amorphous silicon films”, Y. Sakuma, K. Ohdaira, T.
Masuda, H. Takagishi, Z. Shen, and T. Shimoda, Jpn. J. Appl. Phys. 53 (2014)
04ER07.
“Passivation quality of a stoichiometric SiNx single passivation layer on crystalline
silicon prepared by Cat-CVD and successive annealing”, Trinh Cham Thi, K.
Koyama, K. Ohdaira, and H. Matsumura, Jpn. J. Appl. Phys. 53 (2014) 022301.
“Liquid-phase explosive crystallization of electron-beam-evaporated a-Si films
induced by flash lamp annealing”, K. Ohdaira and H. Matsumura, J. Cryst. Growth
362 (2013) 149.
“Flash-lamp-induced explosive crystallization of amorphous germanium films
leaving behind periodic microstructures”, K. Ohdaira and H. Matsumura, Thin Solid
Films 524 (2012) 161.
“Development of thermal conductivity measurement system using the 3ω method
and application to thermoelectric particles”, S. Nishino, K. Suekuni, K. Ohdaira,
and M. Koyano , J. Electronic Materials (2014) DOI: 10.1007/s11664-014-2993-9.
“Structural and thermoelectric properties" of Cu6Fe4Sn12Se32 single crystal”, K.
Suekuni, K. Tsuruta, H. Fukuoka, and M. Koyano, J. Alloys and Compounds, 564
(2013) 91.
“Thermoelectric Properties of Mineral Tetrahedrites Cu 10 Tr 2 Sb 4 S 13 with Low
Thermal Conductivity”, K. Suekuni, K. Tsuruta, T. Ariga, M. Koyano, Applied
Physics Express, 5 (2012) 051201.
“Single crystal growth of Bi-Sb-Te thermoelectric materials by halide chemical
vapor transport technique”, M. Koyano, J. Tanaka, K. Suekuni and T. Ariga, J.
Electronic Materials, 41 (2012) 1317.
“Measurement of Local Peltier Constant at a Micro Contact”, M. Koyano, and N.
Akashi, J. Electronic Materials, 37 (2009) 1037.
Adaptable & Seamless Technology Transfer Program through Target-driven R&D (A-STEP),
JST, 2012-2013, Development of the high-productive technology of polycrystalline silicon
films for solar cells, K. Ohdaira, 1,300,000 JPY
Strategic Basic Research Programs PRESTO, 2009-2013, JST, Formation of high-quality
polycrystalline silicon films on glass substrates by flash-lamp-induced crystallization, K.
Ohdaira, 40,000,000 JPY
Grant-in-Aid for Scientific Research (C), 2010-2012, M. Koyano, 3,400,000 JPY
12
Akabori Group
Oshima Group
Associate Professor Masashi Akabori
Associate Professor Yoshifumi Oshima
E-mail: akabori@jaist.ac.jp
E-mail: oshima@jaist.ac.jp
Spintronics in Semiconductor
Nanowires
Nanomaterial Science
by transmission electron microscope
Outline:
Outline:
Spintronics involves controlling not only electric charge but also spin
direction for future information technology. The most typical spintronics device using a semiconductor is a spin field-effect transistor
(spin-FET), which consists of a semiconductor channel having large
spin-orbit coupling (InAs, InGaAs, InSb, InGaSb etc.) and ferromagnetic metal (FM) electrodes. From now, we plan to use semiconductor nanowire (NW) as the channel, and spin relaxation (caused by
the spin-orbit coupling and elastic scattering) is expected to be suppressed in the spin-FET. Therefore, we investigate NW-FM hybrid
structures for future spintronics applications.
We have developed an experimental system of combining a scanning tunneling microscope (STM) with ultra-high vacuum transmission electron microscope (TEM) and directly obtained relationship
between atomic structure and electrical conductance of nanoscaled material. For example, quantization phenomena of gold contacts have been clarified. We will devise such unique experimental
systems based on TEM and clarify relationship between atomic
structure and physical and/or chemical properties of frontier materials. Our final goal is discovery of frontier materials, which is based
on understanding physical and/or chemical properties at an atomic
scale.
“Magneto-transport properties of InAs nanowires laterally-grown by selective area
molecular beam epitaxy on GaAs (110) masked substrates”, M. Akabori and S. Yamada, AIP
Conf. Proc., Vol. 1566, pp. 219-220 (2013).
“High-efficient long spin coherence electrical spin injection in CoFe/InGaAs
two-dimensional electron gas lateral spin-valve devices”, S. Hidaka, M. Akabori, and S.
Yamada, Appl. Phys. Express, Vol. 5, pp. 113001-1-3 (2012).
“Selective area molecular beam epitaxy of InAs on GaAs (110) masked substrates for direct
fabrication of planar nanowire field-effect transistors”, M. Akabori, T. Murakami, and S.
Yamada, J. Crystal Growth, Vol. 345, pp. 22-26 (2012).
“Spin-orbit coupling and phase coherence in InAs nanowires”, S. Estévez Hernández, M.
Akabori, K. Sladek, Ch. Volk, S. Alagha, H. Hardtdegen, M. G. Pala, N. Demarina, D.
Grützmacher, and Th. Schäpers, Phys. Rev. B, Vol. 82, pp. 235303-1-7 (2010).
“Influence of growth temperature on the selective area MOVPE of InAs nanowires on GaAs
(111) B using N2 carrier gas”, M. Akabori, K. Sladek, H. Hardtdegen, Th. Schäpers, and D.
Grützmacher, J. Crystal Growth, Vol. 311, pp. 3813-3816 (2009).
“Reversible Contrast in Focus Series of Annular Bright Field Images of a Crystalline
LiMn2O4 Nanowire”, S. Lee, Y. Oshima, et al., Ultramicroscopy 125 (2013) 43-48.
“In situ TEM observation of controlled gold contact failure under electric bias”, Y. Oshima
and Y. Kurui, Phys. Rev. B 87(R) (2013) 081404
“Quantitative Annular Dark Field STEM Image of Silicon Crystal using a Large Convergent
Electron Probe with a 300-kV Cold Field Emission Gun”, S. Kim, Y. Oshima, et al., J. Elect.
Micro. 60 (2011) 109-116.
“One-by-One Introduction of Single Lattice Planes in a Bottlenecked Gold Contact during
Stretching”, Y. Oshima, Y. Kurui and K. Takayanagi J. Phys. Soc. Jpn. 79 (2010) 054702.
Editor’s Choice
“Direct Imaging of Lithium Atoms in LiV2O4 by a Spherical Aberration Corrected Electron
Microscope”, Y. Oshima, et al. J. Elect. Micro. 59 (2010) 457.
“Detection of arsenic dopant atoms in a silicon crystal using a spherical aberration corrected
scanning transmission electron microscope”, Y. Oshima, Y. Hashimoto, et al., Phys. Rev. B
81 (2010) 035317.
Grant-in-Aid for Scientific Research (C), JSPS, 2012-2014, M. Akabori, 4,100,000 JPY.
Grant-in-Aid for Young Scientists (B), JSPS, 2010-2011, M. Akabori, 3,200,000 JPY.
Grant-in-aid for Scientific Research C, 2010-2012 Y. Oshima, 3,500,000 JPY
JST-PRESTO, 2008-2011, Y. Oshima, 40,000,000 JPY
Research Grant, Renesas Electronics, 2011-2013, Y. Oshima, 3,000,000 JPY
JST-CREST, 2011-2014, K. Takayanagi, 200,000,000 JPY
JST-CREST, 2004-2010, K. Takayanagi, 500,000,000 JPY
13
Matsumi Group
Nagao Group
Professor Noriyoshi Matsumi
Assistant Professor Raman Vedarajan
Associate Professor Yuki Nagao
E-mail: matsumi@jaist.ac.jp
E-mail: ynagao@jaist.ac.jp
Design of Energy Materials
using Hetero Atom Chemistry
Nanoprotonics – Creation of
Emergent Chemical Devices –
Outline:
Outline:
Today, lithium secondary batteries are attracting much attention, not
only for use in various mobile devices but also in automobiles, solar
energy storage systems and so forth. However, common electrolytes
generally show limited selectivity for lithium transport. Therefore, we
are developing various electrolytes, mainly with anion receptor or
with highly-dissociable lithium salt structure, making the most of
heteroatom chemistry. At the same time, since the most important
matter is safety problem, we are conducting studies for creation of
flame-retardant electrolytes for a new class of batteries.
Fuel cells, which generate electricity through the reaction of hydrogen with oxygen to produce water, are ideal power sources for use
by future generations. They are suitable for use by a low-carbon
society. Protonics is based on integrated sciences and technologies
using hydrogen. However, more research is necessary for application to the development of the Pt-free electrocatalysts and fuel
cells. We design and create fuel cells using the concepts of "nanoprotonics" and "chemical devices" to create nanoprotonics fuel
cells. Furthermore, we are developing technologies for future use in
the energy research area, and also for many related research areas
that can benefit from these concepts.
“π-Conjugated polycarbazole-boron complex as calorimetric fluoride ion sensor” ,
R. Vedarajan, Y. Hosono, N. Matsumi, Solid State Ionics, 262 (2014) 795.
“Design of organic-Inorganic hybrid electrolytes composed of borosilicate and
allylimidazolium type ionic liquids” , K. S. Smaran, R. Vedarajan, N. Matsumi, Int. J.
Hydrogen Energy, 39 (2014) 2936.
“Synthesis of imidazolium salt-terminated poly(amidoamine)-typed POSS-core
dendrimers and their solution and bulk properties” , K. Naka, R. Shinke, M.
Yamada, F. D. Belkada, Y. Aijo, Y. Irie, S. R. Shankar, K. S. Smaran, N. Matsumi, S.
Tomita, S. Sakurai, Polym. J, 46 (2014), 42.
“Synthesis of boric ester type ion-gels by dehydrocoupling of cellulose with
hydroboranes in ionic liquid” , N. Matsumi, N. Yoshioka, K. Aoi, Solid State Ionics,
226 (2012) 37.
“Ionic liquid pillar[5]arene:Its ionic conductivity and solvent-free complexation with
a guest” , T. Ogoshi, N. Ueshima, T. Yamagishi, Y. Toyoda, N. Matsumi, Chem.
Commun., 48 (2012) 3536.
N. Matsumi, SPSJ Award for the Outstanding Paper in Polymer Journal Sponsored
by ZEON (2009)
“Proton conductivity enhancement in oriented, sulfonated polyimide thin ﬁlms”, K.
Krishnan, H. Iwatsuki, M. Hara, S. Nagano, Y. Nagao, J. Mater. Chem. A 2 (2014)
6895.
“Effects of Nafion impregnation using inkjet printing for membrane electrode
assemblies in polymer electrolyte membrane fuel cells”, Z. Wang, Y. Nagao,
Electrochim. Acta 129 (2014) 343.
“Surface proton transport of fully protonated poly(aspartic acid) thin films on
quartz substrates”,Y. Nagao, T. Kubo, Appl. Surf. Sci., accepted.DOI:
10.1016/j.apsusc.2014.06.085.
“Influence of Confined Polymer Structure on Proton Transport Property in
Sulfonated Polyimide Thin Films”, K. Krishnan, T. Yamada, H. Iwatsuki, M. Hara, S.
Nagano, K. Otsubo, O. Sakata, A. Fujiwara, H. Kitagawa, Y. Nagao, Electrochemistry, accepted.
“Enhancement of Proton Transport in an Oriented Polypeptide Thin Film”, Y.
Nagao, J. Matsui, T. Abe, H. Hiramatsu, H. Yamamoto, T. Miyashita, N. Sata, H.
Yugami, Langmuir, 29 (2013) 6798.
“Highly Oriented Sulfonic Acid Groups in a Nafion Thin Film on Si Substrate”, Y.
Nagao, J. Phys. Chem. C 117 (2013) 3294.
NEDO
Grant for Industrial Technology Research, 2009-2013, Design of Organic-Inorganic Hybrid
Type Ion-gels, N. Matsumi, 40,000,000 JPY
TOYOTA Advanced Technology Collaborative Foundation, 2013-2014, N. Matsumi (Title
and amount are not in public.)
The Ogasawara Foundation for the Promotion of Science & Engineering, 2014 – 2015,
2,500,000 JPY
The Kyoto Technoscience Center, 2014, 1,000,000 JPY
NEXT Program, JSPS, 2011-2014, Y. Nagao, 66,000,000 JPY
PRESTO, JST, 2010-2011, Y. Nagao, 15,138,000 JPY
The Foundation Hattori-Hokokai, 2010-2011, Y. Nagao, 1,000,000 JPY
TEPCO Memorial Foundation, 2010, Y. Nagao, 830,000 JPY
14
Ebitani Group
Maenosono Group
Professor Kohki Ebitani
Assistant Professor Shun Nishimura
Professor Shinya Maenosono
Assistant Professor Derrick M. Mott
E-mail: ebitani@jaist.ac.jp
E-mail: shinya@jaist.ac.jp
Nano-Structured Heterogeneous
Catalysts for Biomass-Derived Material
Conversion into Valuable Chemicals
Nanoparticle Science and Technology
From Synthesis to Applications
Outline:
Outline:
Problems concerning energy, resources, and health will be solved
by converting inexpensive materials into highly valuable compounds
with high atom efficiency and low E-factor of the chemical reaction.
Our lab is, therefore, focusing on development of nano-structured
heterogeneous catalysts for efficient transformations of biomassderived materials into value-added chemicals. Using a one-pot
sequential reaction system consisting of solid acid and base catalysts, various sugars can be converted into furfurals, which are
further oxidized to the corresponding carboxylic acids in water with
molecular oxygen. Fine structure of the catalytically-active sites has
been determined by XAFS using synchrotron radiation facility.
Nanoparticles (NPs) have intermediate properties between atoms
(molecules) and bulk crystals. We explore the frontiers of synthesis,
higher-order structuring, and functionalization of NPs. In addition,
we aim to develop practical applications of NPs in collaboration
with industry. Our research in JAIST has focused on two main areas
of interest in the field of materials chemistry and nanotechnology.
The first area involves wet chemical synthesis of semiconductor NPs
with controlled size, shape and composition for optoelectronic and
thermoelectric device applications. The second area is focused on
the synthesis and biological application development of monometallic and alloyed multimetallic NPs．
“Base-free chemoselective transfer hydrogenation of nitroarenes to anilines with
formic acid as hydrogen source by reusable heterogeneous Pd/ZrP catalyst”, J.
Tuteja, S. Nishimura, and K. Ebitani, RSC Adv. in press.
“Synthesis of high-value organic acids from sugars promoted by hydrothermally
loaded Cu oxide species on magnesia”, H. Choudhary, S. Nishimura, and K.
Ebitani, Appl. Catal. B: Environ. 162 (2015) 1.
“Effect of stabilizing polymers on catalysis of hydrotalcite-supported platinum
nanoparticles for aerobic oxidation of 1,2-propanediol in aqueous solution at room
temperature”, D. Tongsakul, S. Nishimura, and K. Ebitani, J. Phys. Chem. C 118
(2014) 11723.
“Production of γ–valerolactone from biomass-derived compounds using formic
acid as a hydrogen source over supported metal catalysts in water solvent”, P. A.
Son, S. Nishimura, and K. Ebitani, RSC Adv. 4 (2014) 10525.
“Direct synthesis of 1,6-hexanediol from HMF over a heterogeneous Pd/ZrP
catalyst using formic acid as hydrogen source”, J. Tuteja, H. Choudhary, S.
Nishimura, and K. Ebitani, ChemSusChem 7 (2014) 96.
“Multicore magnetic FePt nanoparticles: controlled formation and properties”, L. A.
W. Green, T. T. Trinh, D. Mott, S. Maenosono, and T. T. K. Nguyen, RSC Adv. 4 (2014)
1039.
“Gold core wüstite shell nanoparticles: suppression of iron oxidation via the electron
transfer phenomenon”, P. Singh, D. Mott, and S. Maenosono, ChemPhysChem 14
(2013) 3278.
“Chemical synthesis of blue-emitting metallic zinc nano-hexagons”, M. T. Nguyen, T.
T. Trinh, D. Mott, and S. Maenosono, CrystEngComm 15 (2013) 6606.
“Electronic transfer as a route to increase the chemical stability in gold and silver
core-shell nanoparticles”, D. M. Mott, A. T. N. Dao, P. Singh, C. Shankar, and S.
Maenosono, Adv. Colloid Interface Sci. 185-186 (2012) 14.
“Manipulation of the electronic properties of gold and silver core−shell
nanoparticles”, D. Mott and S. Maenosono, Functional Nanoparticles for Bioanalysis,
Nanomedicine, and Bioelectronic Devices Volume 1 (ACS Symposium Series), Edited
by Maria Hepel and Chuan-Jian Zhong, Chapter 13, pp.327-358, American Chemical
Society (2012)
Grant-in-Aid for Scientific Research (C), MEXT, 2009-2011, K. Ebitani, 3,600,000 JPY
Intellectual Property Promotion Highway, JST, 2012, S. Nishimura, 3,000,000 JPY
Grant-in-Aid for Scientific Research (C), MEXT, 2010-2012, S. Maenosono, 3,630,000 JPY
Research Grant, The Mitani Foundation for Research and Development, 2012, S. Maenosono, 1,000,000 JPY
Research Grant, The Kazuchika Okura Memorial Foundation, 2012, S. Maenosono,
1,000,000 JPY
Grant-in-Aid for Challenging Exploratory Research, MEXT, 2014-2016, S. Maenosono,
3,900,000 JPY
15
Terano Group
Shinohara Group
Professor Minoru Terano
Associate Professor Ken-ichi Shinohara
E-mail: terano@jaist.ac.jp
E-mail: shinoken@jaist.ac.jp
Development of Next-generation
Highly Functional Polyolefin Materials
Single-Molecules Imaging of Polymers
Outline:
Outline:
Polyolefin is still the most important synthetic polymer, which provides full material advantages and allows state-of-the-art technologies. We have explored the potential of polyolefin materials through
rational understanding and advanced material design. For providing
next-generation materials for the coming sustainable society, we
especially focus on the combination of three key technologies:
molecularly-tailored olefin polymerization catalysts, polyolefin with
exceptional stability over decades, and highly strong & functional
nanocomposite materials. We welcome your participation in our
group, to become a future leader in the fast-growing and amazing
polyolefin society in your country.
Polymers are very useful materials that display many excellent properties. However, it is difficult to discuss the correlation between
their molecular structures and functions, since these are diverse,
dynamic and can be very complex. If the structure and functions of a
polymer are directly observed at the molecular level, then the relationships between polymer structures and functions can be clarified.
Recently, we have succeeded in the molecular imaging of a longchain branch structure in low-density polyethylene (LDPE) for the
first time in the world, using a high-speed (fastscanning) polymerAFM. Furthermore, by synthesis and single-molecules imaging, we
have developed a flexible "live" nanomachine with a macromolecular motor utilizing thermal fluctuation.
“Coadsorption model for first-principle description of roles of donors in
heterogeneous Ziegler-Natta propylene polymerization”, T. Taniike and M.
Terano, J. Catal. 293 (2012) 39.
“Vanadium–modified novel bimetallic phillips catalyst with high branching ability
for ethylene polymerization”, A. Matta, Y. Zeng, T. Taniike, and M. Terano,
Macromol. React. Eng. 6 (2012) 346.
“Structure-performance relationship in Ziegler-Natta olefin polymerization with
novel core-shell MgO/MgCl2/TiCl4 catalysts”, T. Taniike, P. Chammingkwan, and
M. Terano, Catal. Commun. 27 (2012) 13.
“Influences of polypropylene grafted to SiO2 nanoparticles on the crystallization
behavior and mechanical properties of polypropylene/SiO2 nanocomposites”, M.
Umemori, T. Taniike, and M. Terano, Polym. Bull. 68 (2012) 1093.
“Kinetic elucidation of comonomer-induced chemical and physical activation in
heterogeneous Ziegler-Natta propylene polymerization”, T. Taniike, B. T. Nguyen,
S. Takahashi, T. Q. Vu, M. Ikeya, and M. Terano, J. Polym. Sci. A: Polym. Chem. 49
(2011) 4005.
“Origin of broad molecular weight distribution of polyethylene produced by
Phillips-type silica-supported chromium catalyst”, K. Tonosaki, T. Taniike, and M.
Terano, J. Mol. Catal. A: Chem. 340 (2011) 33.
K. Shinohara, PCT/JP2013/ 84818 (2014).
“Structural Analysis of Polymer Chains by Scanning Probe Microscope”, K. Shinohara, New Development of Surface Treatments for Polymers pp 115-124, CMC
Publishing (Tokyo, Japan), ISBN-978-4-7813-0595-0 (2012).
“High-Speed Scanning Probe Microscope”, K. Shinohara, JP-A-2012-032389
(2012).
“Single-Molecule Imaging of Photodegradation Reaction in a Chiral Helical
π-Conjugated Polymer Chain”, K. Shinohara, N. Kodera, T. Oohashi, J. Polym. Sci.
Part A: Polym. Chem. 48, 4103–4107 (2010).
“Single-Molecule Imaging of a Micro-Brownian Motion of a Chiral Helical
π-Conjugated Polymer as a Molecular Spring Driven by Thermal Fluctuations”, K.
Shinohara, N. Kodera, T. Ando, Chem. Lett. 38, 690-691 (2009).
Dutch Polymer Institute Research Proposals on Polyolefins, 2012-2016, M. Terano, T.
Taniike, 300,000 EUR
Grant-in-Aid for Young Scientists (B), MEXT, 2012-2013, T. Taniike, 4,290,000 JPY
Dutch Polymer Institute Research Proposals on Polyolefins, 2009-2012, M. Terano, T.
Taniike, 276,000 EUR
Collaboration projects with leading chemical companies (Japan Polychem, Mitsui Chemical, Samsung-Total Petrochemicals, Sumitomo chemicals, Toho Titanium, etc.)
Grant-in-Aid for challenging Exploratory Research, MEXT, 2013-2014, “Single-Molecules
Imaging of a Movement of a Short Chain along a Long Polymer Chain”, K. Shinohara,
4,160,000 JPY.
The System Development Program for Advanced Measurement and Analysis (SENTAN)
from the Japan Science and Technology Agency (JST), 2004-2009, “Development of 3-D
High Resolution Microscope for Dynamic Structural Analysis of Bio-molecules”, K. Shinohara, 51,100,000 JPY.
16
Yamaguchi Group
Kaneko Group
Professor Masayuki Yamaguchi
Assistant Professor Shogo Nobukawa
Associate Professor Tatsuo Kaneko
Research Lecturer Seiji Tateyama
E-mail: m_yama@jaist.ac.jp
E-mail: kaneko@jaist.ac.jp
Design of Advanced Polymeric
Materials by Rheological Approach
Biomolecule Materialization
Based on Multifunctional Polymers
Outline:
Outline:
Rheology - the new science of deformation and flow for a material
showing complicated mechanical responses - is necessary in order
to develop advanced polymeric materials. Our laboratory is carrying
out material design of functional, high-performance polymers based
on the rheological approach to create novel displays, nextgeneration automobile parts, self-repairing polymers, ecofriendly
materials including biomass-based plastics, and so on. Moreover,
innovative polymer processing is also studied with our industrial
partners, considering trouble-shooting of actual processing operations.
Carbon in the earth's atmosphere is stored by photosynthetic activity and stocked as biomass molecules. In Kaneko laboratory,
biomass molecules are used to develop environmentally-fiendly
materials using cutting-edge science. In particular, we focus on aromatic molecules with a lot of functions mediated by π-electrons, and
induce high-performance in polymeric materials. By this strategy,
we have developed environmentally-friendly materials with the
highest heat-resistance and mechanical strength from biomass molecules. Photofunctionality, liquid crystallinity, and water-related
properties in these materials are also our research targets.
“Wavelength Dispersion of Orientation Birefringence for Cellulose Esters Containing
Tricresyl Phosphate”, A. M. Mohd Edeerozey, M. Tsuji, Y. Shiroyama, M. Yamaguchi,
Macromolecules, 44 (10), 3942-3949 (2011).
“Autonomic Healing and Welding by Interdiffusion of Dangling Chains in Weak
Gel”, M. Yamaguchi, R. Maeda, R. Kobayashi, T. Wada, S. Ono, S. Nobukawa,
Polymer International, 61 (1) 9-16 (2012).
“Effect of Thermal Modification on Rheological Properties of Polyethylene Blends”,
M. Siriprumpoonthum, S. Nobukawa, Y. Satoh, H. Sasaki, M. Yamaguchi, J.
Rheology, 58 (2), 449-466 (2014).
“Extraordinary wavelength dispersion of birefringence in cellulose triacetate film
with anisotropic nanopores”, S. Nobukawa, H. Shimada, Y. Aoki, A. Miyagawa, V. A.
Doan, H. Yoshimura, Y. Tachikawa, M. Yamaguchi, Polymer, 55 (15), 3247-3253
(2014).
“Crystallization Behavior and Dynamic Mechanical Properties of Poly(L-Lactic Acid)
with Poly(Ethylene Glycol) Terminated by Benzoate”, T. Huang, M. Miura, S.
Nobukawa, M. Yamaguchi, J. Polym. Environment, 22 (2), 183-189 (2014).
“Bio-based polyimides from 4-aminocinnamic acid photodimer”, P. Suvannasara, S.
Tateyama, A. Miyasato, K. Matsumura, T. Shimoda, N. Takaya, T. Kaneko, et al.
Macromolecules, 47 (2014) 1586.
“ Ionic state and chain conformation for aqueous solutions of supergiant cyanobacterial polysaccharide”, T. Mitsumata, T. Miura, N. Takahashi, M. Kawai, M. Okajima, and
T. Kaneko, Phys. Rev. E, 87 (2013) 042607.
“Hyperbranching Polycoumarates with Photofunctional Multiple Shape-Memory”, S.
Wang, D. Kaneko, M. Okajima, K. Yasaki, S. Tateyama, and T. Kaneko, Angew.
Chem. Int. Ed. 52 (2013) 11143.
“Hydrotalcites catalyze the acidolysis polymerization of phenolic acid to create highly
heat-resistant bioplastics”, M. Chauzar, S. Tateyama, K. Ebitani, T. Kaneko, et al. Adv.
Funct. Mater. 22 (2012) 3438.
“Environmentally-Degradable, High-performance Plastics from Phenolic Phytomonomers”, T. Kaneko, et al. Nature Mater. 5 (2006) 966.
JST, Regional Research and Development Resources Utilization Program, 2008-2012, Material
design of extraordinary wavelength dispersion film, M. Yamaguchi, S. Nobukawa,
169,990,000 JPY
Grant-in-Aid for Scientific Research (B), 2010-2013, Localization of carbon nanotube in a
polymeric multi-components system, M. Yamaguchi, 11,500,000 JPY
Research Grant from Suzuki Foundation, 2010-2012, M. Yamaguchi, 9,300,000 JPY
Advanced Low Carbon Technology Research and Development Program (ALCA), JST
Strategic Basic Research Program, 2011-2015, T. Kaneko, 300,000,000 JPY
Core Research for Evolutionary Science and Technology (CREST), JST Strategic Basic
Research Program, 2013-2018, T. Kaneko, 100,000,000 JPY
Grant for Industrial Technology Research, NEDO, 2007-2011, T. Kaneko, 65,000,000 JPY
Creation of Regional Innovation Science and Technology Incubation Program in Advanced
Regions “Practical Application Research”, JST, 2007-2010, T. Kaneko, 72,000,000 JPY
17
Matsumura Group
Taniike Group
Associate Professor Kazuaki Matsumura
Associate Professor Toshiaki Taniike
E-mail: mkazuaki@jaist.ac.jp
E-mail: taniike@jaist.ac.jp
Functional Polymeric Biomaterials
for Controlling the Functions of
Living Systems
Advanced Material Design based on
Synergetic Exploration, Learning, and
Prediction
Outline:
Outline:
The creation of functional polymers is a widely-studied process for
applications in biomaterials and tissue engineering materials.
Polyampholytes are polymers that have both positive and negative
ions in 1 molecule. Our results have revealed that several kinds of
polyampholytes have a cryoprotective effect on cells in solution. We
will investigate and develop membrane-protective materials that can
control cell functions, by clarifying the mechanisms underlying such
cryoprotective effects. We also perform basic and applied research
on materials well-matched to living systems; this research is aimed
toward the regeneration of functions in tissue engineering.
Under urgent pressure for a shift to a sustainable society, conceptual
and technical maturation of materials science makes it increasingly
difficult to find truly new materials. The mission of Taniike Laboratory
is to renovate materials science by establishing a new material design
scheme based on synergetic combination of high-throughput experimentation (exploration), multivariate analysis for quantitative clarification of structure-property relationships (learning), and quantum
chemical calculation (prediction). We deliver twofold outputs: serendipitous catalytic and polymeric materials in response to the needs of
the times, and next-generation material scientists who have become
familiar with this acquire the unique material design scheme.
“Self-degradation of tissue adhesive based on oxidized dextran and poly-L-lysine”,
K. Matsumura, N. Nakajima, H. Sugai, and SH. Hyon, Carbohydr. Polym. (2014) in
press.
“Protein cytoplasmic delivery using polyampholyte nanoparticles and freeze concentration”, S. Ahmed, F. Hayashi, T. Nagashima, and K. Matsumura, Biomaterials 36
(2014) 6508.
“Hydrogelation of dextran-based polyampholytes with cryoprotective properties via
click chemistry”, M. Jain, R. Rajan, SH. Hyon, and K. Matsumura, Biomater. Sci. 2
(2014) 308.
“Cryoprotective properties of completely synthetic polyampholytes via reversible
addition-fragmentation chain transfer (RAFT) polymerization and the effects of
hydrophobicity”, R. Rajan, M. Jain, and K. Matsumura, J. Biomater. Sci. Polym. Ed.
24 (2013) 1767.
“Long-term cryopreservation of human mesenchymal stem cells using carboxylated
poly-L-lysine without the addition of proteins or dimethyl sulfoxide”, K. Matsumura,
F. Hayashi, T. Nagashima, and SH. Hyon, J. Biomater. Sci. Polym. Ed. 24 (2013) 1484.
“Sol-gel synthesis of nano-sized silica in confined amorphous space of
polypropylene: impact of nano-level structures of silica on physical properties of
resultant nanocomposites”, K. Takeuchi, M. Terano, and T. Taniike, Polymer 55
(2014) 1940.
“Polypropylene-grafted nanoparticles as a promising strategy for boosting physical
properties of polypropylene-based nanocomposites”, T. Taniike, M. Toyonaga, and
M. Terano, Polymer 55 (2014) 1012.
“Multilateral characterization for industrial Ziegler–Natta catalysts toward elucidation
of structure–performance relationship”, T. Taniike, T. Funako, and M. Terano, J.
Catal. 311 (2014) 33.
“The use of donors to increase the isotacticity of polypropylene”, T. Taniike, and M.
Terano, Adv. Polym. Sci. 257 (2013) 81.
“Coadsorption model for first-principle description of roles of donors in
heterogeneous Ziegler-Natta propylene polymerization”, T. Taniike, and M. Terano,
J. Catal. 293 (2012) 39.
Grant-in-Aid for Young Scientists (B), MEXT, 2013-2014, K. Matsumura, 3,120,000 JPY
Grant from Collaborative Research Project organized by the Interuniversity Bio-Backup
Project (IBBP), 2013-2014, K. Matsumura, 5,250,000 JPY
Grant from the Canon Foundation, 2012-2013, K. Matsumura, 13,000,000 JPY
A-STEP Feasibility Study, JST 2011, K. Matsumura, 1,700,000 JPY
Grant-in-Aid for Young Scientists (B), 2012-2013, T Taniike, 4,290,000 JPY
Grant-in-Aid for Young Scientists (B), 2009-2011, T Taniike, 3,120,000 JPY
Dutch Polymer Institute Research Proposals on Polyolefins, 2012-2016, T Taniike et al.,
300,000 EUR
Dutch Polymer Institute Research Proposals on Polyolefins, 2009-2012, T Taniike et al.,
276,000 EUR
*Collaboration with companies: IRPC Public, Japan Polychem, Sumitomo Chemials, etc.
18
Takamura Group
Hiratsuka Group
Professor Yuzuru Takamura
Associate Professor Yuichi Hiratsuka
E-mail: takamura@jaist.ac.jp
E-mail: yhira@jaist.ac.jp
Microfluidic Devices and Sensors for
Biochemical and Medical Applications
Micro-Mechanical Devices Powered
by Motor Proteins
Outline:
Outline:
We are studying next generation biochip techniques for various
biomedical and environmental applications, employing semiconductor technology, nanomaterials / biomolecules, micro / nanofluidics,
and lab-on-a-chip techniques. Our interests extend to a wide range
of topics in the fusion of nanotechnology and biotechnology, to
understanding of phenomena at the nano & micro scale, and to
practical applications such as highly-sensitive point-of-care biosensors, manipulation of liquids on chip, analysis of single cells and
single molecules, LEP-AES ultra-compact elemental analyzer, and
various bio/chemical processing units.
Living organisms have developed diverse functions through evolution over a long period of time. Some functions are related to mobility, including muscle contraction, bacteria' s swimming and cell
division. Nanometer proteins called motor proteins are integrated
into motion assemblies with dimensions ranging from the
micrometer-scale (bacteria) to the meter-scale (muscle). A motor
protein is a molecular machine that converts chemical energy into
dynamic force with great efficiency. This is an excellent property
that conventional artificial motors do not have. In our laboratory, we
are developing biohybrid micromachines using organic motors and
micro-fabrication technology.
“High sensitive elemental analysis for Cd and Pb by liquid electrode plasma atomic
emission spectrometry with quartz glass chip and sample flow”, A. Kitano, A.
Iiduka, T. Yamamoto, Y. Ukita, E. Tamiya, and Y. Takamura, Anal. Chem. 83 (2011)
9424.
“Trapping probability analysis of a DNA trap using electric and hydrodrag force
fields in tapered microchanels”, Y. Tomizawa, E. Tamiya, and Y. Takamura, Phys.
Rev. E 79 (2009) 051902.
“Label-free protein biosensor based on aptamer-modified carbon nanotube
field-effect transistors,” K. Maehashi, T. Katsura, K. Matsumoto, K. Kerman, Y.
Takamura, and E. Tamiya, Anal. Chem. 79 (2007) 782.
“Separation of long DNA molecules by quartz nanopillar chips under a direct
current electric field”, N. Kaji, Y. Tezuka, Y. Takamura, M. Ueda, T. Nishimoto, H.
Nakanishi, Y. Horiike, Y. Baba, Anal. Chem. 76 (2004) 15.
“Low-voltage electroosmosis pump for stand-alone microfluidics devices”, Y.
Takamura, H. Onoda, H. Inokuchi, S. Adachi, A. Oki, and Y. Horiike,
Electrophoresis 24 (2003) 185.
"Self-organized optical device driven by motor proteins", Susumu Aoyama, Masahiko
Shimoike, and Yuichi Hiratsuka, Proc. Nati. Acad. Sci. vol. 110 no. 41, 16408-16413
(2013)
“Utilization of myosin and actin bundles for the transport of molecular cargo “, H.
Takatsuki, K. M. Rice, S. Asano, B. S. Day, M. Hino, K. Oiwa, R. Ishikawa, Y. Hiratsuka,
T. Q. P. Uyeda, K. Kohama, and E. R. Blough, Small 6 (2010) 452.
“Loading and unloading of molecular cargo by DNA-conjugated microtubule” , S.
Taira, Y. Z. Du, Y. Hiratsuka, T. Q. P. Uyeda, N. Yumoto, and M. Kodaka, Biotech.
Bioeng. 99 (2008) 734.
“Bacteria powered microrotary motor “, Y. Hiratsuka, Bionics 26 (2007) 68.
“Three approaches to assembling nano-bio-machines using molecular motors “, Y.
Hiratsuka, T. Kamei, N. Yumoto, and T. Q. P. Uyeda, NanoBiotechnol. 2 (2006) 101.
“Toward a microrotary motor driven by motor Proteins “, Y. Hiratsuka and S.
Takeuchi, MEMS2007 (2007) 695.
“Micro-rotary motor powered by bacteria. “, Y. Hiratsuaka, M. Miyata, T. Tada and T.
Q. P. Uyeda, Proc. Nat. Acad. Sci. 103 (2006) 13618.
Knowledge Cluster Initiative, MEXT, 2007-2013, Y. Takamura, 66,500,000 JPY
A-STEP Feasibility Study, JST, 2009-2010, Y. Takamura, 5,000,000 JPY
Grant-in-Aid for Scientific Research (B), MEXT, 2007-2011, Y. Takamura, 14,400,000 JPY
Grant-in-Aid for Scientific Research in Priority Areas, MEXT, 2007-2009, Y. Takamura, 4,600,000 JPY
Strategic Support Industry Project for Key Tech, METI, 2011-2011, Y. Takamura, 3,355,000 JPY
PRESTO, JST, 2003-2007, Y. Takamura, 41,950,000 JPY
Dev. Univ. Venture, JST, 2004-2007, Y. Takamura, 108,550,000JPY
PRESTO, JST, 2006-2010, Y. Hiratsuka, 40,000,000 JPY
Grant-in-Aid for Scientific Research, MEXT, 2008-2010, Y. Hiratsuka, 3,500,000 JPY
Grant-in-Aid for Scientific Research(B), MEXT, 2010-2013, Y. Hiratsuka, 14,400,000 JPY
Grant-in-Aid for Scientific Research, MEXT, 2012-2014, Y. Hiratsuka, 4,050,000 JPY
Grant-in-Aid for Scientific Research on Innovation Area, 2012.4-2018.3, “Molecular robotics”, Yuichi Hiratsuka, 24,000,000 JPY
19
Hohsaka Group
Fujimoto Group
Professor Takahiro Hohsaka
Assistant Professor Takayoshi Watanabe
Professor Kenzo Fujimoto
Assistant Professor Takashi Sakamoto
E-mail: hohsaka@jaist.ac.jp
E-mail: kenzo@jaist.ac.jp
Protein Engineering with Nonnatural
Amino Acids
Challenge for Bio-science
and Bio-innovation from Chemistry
Outline:
Outline:
Proteins are made up of only 20 types of amino acids. Incorporation
of nonnatural amino acids into proteins greatly expands the possibilities of protein engineering. We have developed a novel technology
allowing us to introduce nonnatural amino acids into specific positions in proteins using expanded genetic codes such as four-base
codons and amber stop codon. Applying this technology, we are
developing nonnatural proteins exhibiting various artificial functions
as well as novel tools for analysis of protein structures and functions.
In addition, industrial applications of this technology are now in
development through collaboration with bio-venture companies.
Our laboratory has been involved in the development of systems to
facilitate the integration of chemistry, biology and physics. On of
our research achievement is the development of an optical control
method for linking and cutting DNA chains, which is quite different
from conventional DNA control using enzymes. Based on our optical control method, we successfully developed a DNA computing
system that conducts logic operations by binalization if a specific
DNA is present. We are working toward applying the system for
quick and precise prediction of susceptibility to certain disease
caused by multiple abnormal DNA.
“Incorporation of fluorescent nonnatural amino acid into sialic acid-binding lectin
for fluorescence detection of ligand-binding”, Y. Ito, T. Hohsaka, Bull. Chem. Soc.
Jpn., 86, 729-735 (2013).
“Synthesis of novel BRET/FRET protein probes containing light-emitting proteins
and fluorescent nonnatural amino acids”, A. Yamaguchi, T. Hohsaka, Bull. Chem.
Soc. Jpn., 85, 576-583 (2012).
“Amber codon-mediated expanded saturation mutagenesis of proteins using a
cell-free translation system”, N. Shozen, T. Watanabe, T. Hohsaka, J. Biosci.
Bioeng., 113, 704–709 (2012).
“’Quenchbodies’: Quench-based antibody probes that show antigen-dependent
fluorescence”, R. Abe, H. Ohashi, I. Iijima, M. Ihara, H. Takagi, T. Hohsaka, H.
Ueda, J. Am. Chem. Soc., 133, 17386-17394 (2011).
“Position-specific incorporation of fluorescent non-natural amino acids into
maltose-binding protein for detection of ligand binding by FRET and fluorescence
quenching”, I. Iijima, T. Hohsaka, ChemBioChem, 10, 999-1006 (2009).
"Photo-regulation of constitutive gene expression in living cells by using ultrafast
photo-cross-linking oligonucleotides", Takashi Sakamoto, Atsuo Shigeno, Yuichi
Ohtaki and Kenzo Fujimoto, Biomaterials Science, 2, 1154–1157 (2014).
“Details of the ultra-fast DNA photocrosslinking reaction of 3-cyanovinylcarbazole
nucleoside; Cis-trans isomeric effect and the application for SNP based
genotyping”, K. Fujimoto, A. Yamada, Y. Yoshimura, T. Tsukaguchi and T.
Sakamoto, J. Am. Chem. Soc. 135(43), 16161-16167 (2013).
“Quick Regulation of mRNA Functions by a Few Seconds of Photoirradiation”, A.
Shigeno, T. Sakamoto, Y. Yoshinaga and K. Fujimoto, Organic & Biomolecular
Chemistry 10(38), 7820-7825 (2012).
“Specific and reversible photochemical labeling of plasmid DNA using
photoresponsive oligonucleotides containing 3-cyanovinylcarbazole”, K. Fujimoto,
K. H. Hiratsuka, T. Sakamoto, and Y. Yoshimura, Molecular BioSystems 8, 491-494
(2012).
“Site-Specific Photochemical RNA Editing”, K. Fujimoto, T. Sakamoto, K. H.
Hiratsuka and Y. Yoshimura, Chem. Commun. 46, 7545-7549 (2010).
Grant-in-Aid for Scientific Research on Innovative Areas, 2013-2017, Development of chemically
expanded biomolecular systems with dynamic ordering function, Takahiro Hohsaka, 93,340,000 JPY
Grant-in-Aid for Scientific Research on Innovative Areas, 2008-2012, Study of protein fluctuations by
introducing nonnatural amino acids, Takahiro Hohsaka, 93,080,000 JPY
Grant-in-Aid for Scientific Research (B), 2007-2009, FRET analysis of protein conformational changes
through position-specific incorporation of fluorescent amino acids, Takahiro Hohsaka, 18,590,000
JPY
Grant-in-Aid for Scientific Research (B), MEXT, 2014-2017, K. Fujimoto, 16,500,000 JPY
Grant-in-Aid for Challenging Exploratory Research, MEXT, 2014-2016, K. Fujimoto, 4,250,000 JPY
Grant-in-Aid for Scientific Research on Innovative Areas, MEXT, 2012-2016 “Development of
Molecular Robots equipped with sensors and intelligence” 、K. Fujimoto、44,000,000 JPY
Grant-in-Aid for Scientific Research (B), MEXT, 2011-2014, K. Fujimoto, 15,500,000 JPY
Grant-in-Aid for Challenging Exploratory Research, MEXT, 2012-2014, K. Fujimoto, 4,160,000 JPY
20
Takagi Group
Hamada Group
Professor Masahiro Takagi
Assistant Professor Naofumi Shimokawa
Associate Professor Tsutomu Hamada
Assistant Professor Ken Nagai
E-mail: takagi@jaist.ac.jp
E-mail: t-hamada@jaist.ac.jp
Membrane Dynamics and
Cellular Signal Transduction
Soft Matter Physics Approach
to Cell-Mimicking Systems
Outline:
Outline:
It is important to understand the physical mechanisms that govern
the dynamic motions and properties of cell plasma membranes.
Liposomes are self-assembled colloidal particles that occur naturally,
and they can be prepared artificially. Liposomes resemble cell membranes in their structure and composition. Conventional liposomes
are very small (<100 nm) but we are using giant vesicles with a
diameter on the order of 10 μm, which are large enough to allow
direct and real-time microscopic observations of membrane dynamics at the level of single vesicles. We are performing many experimental studies using both giant vesicles and actual living cells.
We use a soft matter physics approach to cell-mimicking systems so
that we can understand the physical principles of biological systems.
Living cells are a form of self-assembled soft matter. Lipid bilayer
membranes are essential components of living organisms. We i)
construct artificial lipid vesicles which produce cellular dynamics,
such as endocytosis and autophagy, ii) elucidate the association of
biological and nonbiological nano-materials on membrane surfaces,
and iii) conduct quantitative analyses based on condensed soft
matter physics.
“The effect of oxysterols on the interaction of Alzheimer's amyloid beta with
model membranes.” , H. T. T. Phan, T. Hata, M. Morita, T. Yoda, T. Hamada, M.
C. Vestergaard, M. Takagi, BBA-Biomembrane, 1828,2487-2495 (2013).
“Ion permeation by a folded multiblock amphiphilic oligomer achieved by hierarchical construction of self-assembled nanopores.” , T. Muraoka, T. Shima, T.
Hamada, M. Morita, M. Takagi, K. Tabata, H. Noji, K. Kinbara, J. Am. Chem. Soc.,
134, 19788–19794 (2012).
“Size-dependent partitioning of nano/micro-particles mediated by membrane
lateral heterogeneity.” , T. Hamada, M. Morita, M. Miyakawa, R. Sugimoto, M.
Vestergaard, M. Takagi, J. Am. Chem. Soc.,134,13990−13996 (2012).
“Photochemical control of membrane raft organization.” , T. Hamada, R.
Sugimoto, T. Nagasaki, M. Takagi, Soft Matter, 7, 220-224 (2011).
“Membrane disk and sphere: controllable mesoscopic structures for the capture
and release of a targeted object” , T. Hamada, R. Sugimoto, M. Vestergaard, T.
Nagasaki, M. Takagi, J. Am. Chem. Soc., 132, 10528-10532 (2010).
"Dynamical formation of lipid bilayer vesicles from lipid-coated droplets across a
planar monolayer at an oil/water interface" H. Ito, T. Yamanaka, S. Kato, T. Hamada,
M. Takagi, M. Ichikawa, K. Yoshikawa, Soft Matter, 9, 9539-9547 (2013).
“Size-dependent partitioning of nano/micro-particles mediated by membrane lateral
heterogeneity” T. Hamada, M. Morita, M. Miyakawa, R. Sugimoto, M. C. Vestergaard, M. Takagi, J. Am. Chem. Soc., 134, 13990−13996 (2012).
“Cell-Sized Liposomes and Droplets: Real-World Modeling of Living Cells” T.
Hamada, K. Yoshikawa, Materials, 5, 2292-2305 (2012).
"Lateral phase separation in tense membranes" T. Hamada, Y. Kishimoto, T. Nagasaki, M. Takagi, Soft Matter, 7, 9061-9068 (2011).
“Membrane disk and sphere: controllable mesoscopic structures for the capture and
release of a targeted object” T. Hamada, R. Sugimoto, M. Vestergaard, T. Nagasaki,
M. Takagi, J. Am. Chem. Soc., 132, 10528-10532 (2010).
"Rhythmic pore dynamics in a shrinking lipid vesicle" T. Hamada, Y. Hirabayashi, T.
Ohta, M. Takagi, Phys. Rev. E Stat. Nonlin. Soft Matter Phys., 80, 051921 (2009).
A Grant-in-Aid for Scientific Research (B) 2014-2016 “Analyses, design and control of 2D
and 3D dynamics of cell-mimetic membrane.” Masahiro Takagi 14,130,000 JPY
A Grant-in-Aid for Challenging Exploratory Research 2013-2014 “Alternatives to animal
testing based on membrane dynamics.” Masahiro Takagi 3,900,000 JPY
A Grant-in-Aid for Scientific Research (B) 2011-2013 “Analysis and control of membrane
raft dynamics.” Masahiro Takagi 13,700,000 JPY
Grant-in-aid for Scientific Research Innovative Areas, MEXT, 2014-2015, T. Hamada, 5,200,000 JPY
Grant-in-aid for Scientific Research Young Scientist (B), JSPS, 2011-2013, T. Hamada, 3,300,000
JPY
Grant-in-aid for Scientific Research Specific Area Research, MEXT, 2009-2010, T. Hamada,
6,600,000 JPY
21
Tsukahara Group
Ohki Group
Professor Toshifumi Tsukahara
Assistant Professor Hitoshi Suzuki
Professor Shinya Ohki
Assistant Professor Yoshitaka Umetsu
E-mail: tukahara@jaist.ac.jp
E-mail: shinya-o@jaist.ac.jp
Development of Innovative Medical
Technology Based on RNA Research
NMR-based Structural and
Functional Biology: From Basics
to Applications of Proteins
Outline:
Outline:
All living organisms including human beings have "genes" , which
are basically composed of the same compounds. Gene expressions
are indicated by quantities and species of RNA molecules, which are
informational materials. We are working on RNA research toward
biomedical applications. mRNAs provide the blueprints of proteins,
the functional molecules, in a cell. Therefore, we can understand the
physical or pathological state in vivo through the information of
mRNA molecules. Our laboratory aims to clarify the features of
RNAs, including their expression profiles and mechanisms of alternative splicing. We hope this research will contribute to the development of novel genetic tests and nucleic acid drugs.
Proteins are functional materials to regulate numerous biological
events in living bodies. Studying their structures and functions is
essential to understand what life is. In our group, an 800MHz-NMR
machine is employed to explore protein conformations, dynamics,
and interactions. Recent research interest is focused on plant
science, especially on proteins related to photosynthesis. We are
also interested in developing new methods for NMR sample preparation. Our results will provide key information for a deeper understanding of functional mechanisms of biomolecules as well as clarify
ways to design new drugs and chemicals to control various biological signaling pathways.
“A View of Pre-mRNA Splicing from RNase R Resistant RNAs“. H. Suzuki and T.
Tsukahara, Int. J. Mol. Sci. 15, (2014), 9331-9342; doi:10.3390/ijms15069331
“Nested introns in an intron: Evidence of multi-step splicing of a large intron in the
human dystrophin pre-mRNA” . H. Suzukia, T. Kameyama, K. Ohe, T. Tsukahara, A.
Mayeda, FEBS Letters. (2013) doi: 10.1016/j.febslet.2013.01.057
“Alternative splicing produces structural and functional changes in CUGBP2” , H.
Suzuki, M. Takeuchi, A. Sugiyama, A. H. M. K. Alam, T. L. Vu, Y. Sekiyama, C. H. Dam,
S. Ohki, and T. Tsukahara, BMC Biochem. 13 (2012) 6.
“Functional gene expression analysis of tissue-specific isoforms of Mef2c” , Y.
Sekiyama, H. Suzuki, and T. Tsukahara, Cell. Mol. Neurobiol. 32 (2012) 129.
“Comprehensive analysis of alternative splicing and functionality in neuronal differentiation of P19 cells” , H. Suzuki, K. Osaki, K. Sano, A. H. M. K. Alam, Y. Nakamura, Y.
Ishigaki, K. Kawahara, and T. Tsukahara, PLoS ONE 6 (2011) e16880.
“Central Cell-Derived Peptides Regulate Early Embryo Patterning in Flowering
Plants” L.M. Costa, E. Marshall, M. Teshaye, K.A.T. Silverstein, M. Mori, Y. Umetsu,
S.L. Otterbach, R. Papareddy, H.G. Dickinson, K. Boutiller, K.A. VandenBosch, S.
Ohki and J.F. Gutierrez-Marcos. Science 344 (2014) 168-172.
“Experimental Conversion of a Defensin into a Neurotoxin: Implications for Origin of
Toxic Function” S. Zhu, S. Peigneur, B. Gao, Y. Umetsu, S. Ohki and J. Tytgat. Mol.
Biol. Evol. 31 (2014) 546-559.
“Evolutionary Relationship and Structural Characterization of the EPF/EPFL Gene
Family” N. Takata, K. Yokota, S. Ohki, M. Mori, T. Taniguchi and M. Kurita. PLOS
ONE (2013) DOI:10.1371/journal.pone.0065183.
“Structural Characterization of a Trapped Folding Intermediate of Pyrrolidone
Carboxyl Peptidase from a Hyperthermophile” M. Mizuguchi, M. Takeuchi, S. Ohki,
Y. Nabeshima, T. Kouno, T. Aizawa, M. Demura, K. Kawano and K. Yutani. Biochemistry 51 (2012) 6089-6096.
“The NMR Structure of Stomagen Reveals the Basis of Stomatal Density Regulation
by Plant Peptide Hormones” S. Ohki, M. Takeuchi and M. Mori. Nat. Commun. 2
(2011) 512.
Grant-in-Aid for Neurological and Psychiatric Diseases, MHLW, 2009-2014, H. Suzuki,
10,300,000 JPY
Grant-in-Aid for Scientific Research (B), JSPS, 2013-2015, T. Tsukahara, 14,200,000 JPY
Grant-in-Aid for Exploratory Research, JSPS, 2014-2015, T. Tsukahara, 3,400,000 JPY
Grant-in-Aid for Scientific Research (C), MEXT, 2008-2011, S. Ohki, 4,200,000 JPY
Seeds Research, JST Innovation Plaza Ishikawa, 2009, S. Ohki, 2,000,000 JPY
SENTAN, JST, 2008-2012, S. Ohki, 45,100,000 JPY
Grant-in-Aid for Scientific Research (C), MEXT, 2013-2016, S. Ohki, 4,500,000 JPY
22
Tsutsui Group
Associate Professor Hidekazu Tsutsui
E-mail: tsutsui@jaist.ac.jp
Molecular Sensors
For Bioelectrical Signals
Outline:
Not only the artificial devices but living organisms also use electric
signals to process information outside and within. Seeking to obtain
insights for principles underlying the signal processing, we investigate molecular sensors for bioelectrical signals. Our research focus
on the three main topics: 1) Electrophysiological and spectroscopic
approaches to reveal molecular mechanisms of natural membrane
protein sensors. 2) Fabrication of artificial molecular sensors and
nano-scale devices for the detection of spatiotemporal regulations
of cellular electrical activities. 3) Biomedical applications of the
sensor technologies, including the development of an efficient drug
screen platform.
“Rapid evaluation of a protein-based voltage probe using a field-induced membrane potential change. “, Tsutsui, H., Y. Jinno, A. Tomita, Y. Okamura, Biochimica
et Biophysica Acta – Biomembranes, in press (2014).
“Improved detection of electrical activity with a voltage probe based on a voltagesensing phosphatase.” , Tsutsui, H., Y. Jinno, A. Tomita, Y. Niino, Y. Yamada, K.
Mikoshiba, A. Miyawaki, Y. Okamura, J. Physiol., 591, 4427- 4437 (2013).
“Optically Detected Structural Change in the N-Terminal Region of the VoltageSensor Domain.” , Tsutsui, H., Y. Jinno, A. Tomita, Y. Okamura, Biophys. J., 105,
108-15 (2013).
“Optical action potential screening on adult ventricular myocytes as an alternative
QT-screen.” , Tian, Q., M. Oberhofer, S. Ruppenthal, A. Scholz, V. Buschmann, H.
Tsutsui, A. Miyawaki, A. Zeug, P. Lipp, and L. Kaestner, Cell. Physiol. Biochem., 27,
281-90 (2011).
“Visualizing voltage dynamics in zebrafish heart.” , Tsutsui, H., S. Higashijima, A.
Miyawaki, and Y. Okamura, J. Physiol. 588, 2017-21 (2010).
“The E1 mechanism in photo-induced beta-elimination reactions for green-to-red
conversion of fluorescent proteins.” , Tsutsui, H., H. Shimizu, H. Mizuno, N. Nukina,
T. Furuta, and A. Miyawaki, Chem. Biol, 16, 1140-1147 (2009).
JST PRESTO, 2009-2014, Next generation technology for spatiotemporal measurement
of membrane electrical signals, Hidekazu Tsutsui, 76,100,000 JPY
JSPS, Grant-in-Aid for Scientific Research on Innovative Areas, 2011-2012 , Detection and
control of spatiotemporal dynamics of cell membrane voltage, Hidekazu Tsutsui,
6,890,000 JPY
JSPS, Grant-in-Aid for Scientific Research on Innovative Areas, 2009-2010 , Precise
functional mapping of cellular electrical activities in vivo, Hidekazu Tsutsui, 6,500,000 JPY
23
Center for Nano Materials and Technology
The Center for Nano Materials and Technology (CNMT) started in 2002 as a renewal of the former Center for New
Materials, and is devoted to advanced research and education on nanotechnology. The Center promotes the
Nanotechnology Education Program. It also supports joint projects in basic research and development of
nanotechnology. Those projects are driven by domestic as well as foreign research groups at the highest level, for which
the Center provides its state-of-the-art facilities.
Research Facilities and Instruments
The Center has special facilities and a variety of
state-of-the-art instruments dedicated to basic research and
development of nanomaterials. The special facilities include
clean rooms and a helium gas liquefaction system. Research
instruments include an 800 MHz NMR, mass spectrometers,
SQUIDs, STMs, TEMs, SEMs, an RBS system and MBE
systems.
Director
Goro Mizutani
Professor
Nano Material Technology Program
Academic Field
Nonlinear optical spectroscopy
and microscopy
Since 2002, the Center has been promoting a systematic
education program, the Nano Material Technology Program,
to provide students and company engineers with a wide
variety of knowledge and techniques regarding current
advanced nanoscience and nanotechnology. This program
includes lectures and training programs on nano-device
fabrication, nano-biotechnology and nano-molecular
analysis.
800 MHz NMR
Scanning Transmission
Electron Microscope
Green Device Research Center
The objective of the center is creation of innovative technologies for the realization of a sustainable society.
Newly-developed nano-size printing using unique solution materials will make sustainability possible.
Outline and Objective
The Green Device Research Center (GD-RC) was established to create new technologies which
embody FACTOR 10 by concentrating state-of-the-art technologies and science assets possessed
by the laboratories in the School of Materials Science in JAIST. FACTOR 10 is a challenging target,
to develop a sustainable society, by enhancing properties and efficiencies of products, processes,
etcetera, more than 10 times compared to conventional technologies.
Director
Tatsuya Shimoda
Professor
Academic Field
Magnetic Material, Electronics Devices
24
Research and Development Activities
For sustainability, so-called printable electronics technology is very attractive to explore.
Creating new printing technology and researching novel solution materials are essential
aspects of our activities. As for printing technology, we have just succeeded in creating a
new process named "nano-Rheology Printing (n-RP)" method, which uses metal-oxide
materials in gel form for printing tiny devices as small as tens of nano-meters. Now, we
have already started to develop transistor arrays for an active matrix back-plane of a
display. Other n-RP related research programs, such as MEMS devices, optical parts and
stacked capacitors, will commence soon.
Satoshi Inoue
Jinwang Li
Manish Biyani
Research Professor
Research
Associate Professor
Research
Associate Professor
Research Center for Highly Environmental
and Recyclable Polymers
To cope with global warming and environmental pollution, polymer technologies will play a great role in developing a sustainable
society. This center aims to develop technologies for a new generation of environmentally-friendly and recyclable polymers, and
also to facilitate their industrialization, through active collaboration with domestic and foreign industrial and research groups.
Research Projects Underway
This center is mainly composed of six research groups that are actively conducting research
and education in their respective fields. The research activities of this center cover these
essential fields, such as 1) catalytic monomer synthesis, 2) polymer synthesis, 3) polymer
physics, and 4) functionalization of polymers.
Director
Masayuki Yamaguchi
Professor
Academic Field
Polymer Rheology, Polymer processing
The following research is being carried out at the center.
・Material design of novel eco-friendly polymers based on applied rheology
・Design of nano-structured catalysts for utilization of biomass-derived materials
・Development of high-performance carbon-minus materials using renewable giant
macromolecules
・Development of bio-based functional polymers for energy devices.
・Development of functional polymer biomaterials
・Development of novel polymer nanocomposites
Research Center for Bio-Architecture
The Center was founded in April 2011, aiming at synthesis and organization of innovative artificial biomolecules and at
development of artificial biosystems.
Synthesis of Artificial Biomolecules and their Organization
Director
Takahiro Hohsaka
Professor
Academic Field
Extended Genetic Engineering,
Biomolecular Engineering
Recent progress in life science has revealed detailed mechanisms of biosystems at a
molecular level. This progress allows us to investigate "Bio-architecture research" which
aims to develop biosystems using biomolecules such as nucleic acids, proteins, and
biomembranes. In the School of Materials Science at JAIST, we have achieved creation of
artificially-modified nucleic acids, proteins, and membranes showing specific functions.
Based on these achievements, the Research Center for Bio-Architecture was founded,
aiming at synthesis and organization of innovative artificial biomolecules and at
development of artificial biosystems. The center also aims at application of achievements in
scientific research to actual medical developments, such as novel therapeutic and
diagnostic drugs.
Research Center for Simulation Science
Development of simulation science and construction of new perspectives
Director
Teruo Matsuzawa
SGI Altix UV1000
This research center aims to develop simulation science and high-level specialists in the
field, and construct new perspectives by tightly integrating information science,
computational science, and data science. The frontier of simulation science, such as
elucidation of complicated phenomena and computer-aided material design, will be
established by a close collaboration between computer science such architecture, high
performance computing, database, formal theory, and data mining, and computational
science focusing on materials and life sciences. The construction of a new paradigm is also
pursued by bridging between fundamental theories, such as data mining, data assimilation,
and formal theory, and more practical physical and chemical problems.
25
The Most Advanced Experimental Equipment
JAIST professors and technical staff cooperate to maintain a variety of advanced equipment, which students and
researchers are encouraged to use freely in their work. By simply attending a brief course on operating techniques,
JAIST researchers (including students) can obtain permission to use the specialized equipment necessary for
research and discovery at the frontiers of today’ s technology. That is to say, any student at JAIST has complete
access to all of our most advanced equipment, a truly ideal environment for this stage of your career.
JAIST has a variety of advanced equipment, listed below, to support research in nano-technology and other
fast-growing fields.
FT-ICR-MS
EPMA
FIB
Research Infrastructure and Equipment
200kV Scanning Transmission Electron Microscope (STEM)
JEM-ARM200F, JEOL
100kV Transmission Electron Microscope (TEM)
H-7100 and H-7650, Hitachi
300kV Transmission Electron Microscope (TEM)
H-9000NAR, Hitachi
Scanning Electron Microscope (SEM)
S-4100, S-4500 and S-5200, Hitachi
400MHz Nuclear Magnetic Resonance Spectrometer (NMR)
AVANCE III 400, Bruker BioSpin
Electron Spin Resonance Spectrometer (ESR)
JES-RE3X, JEOL
X-ray Diffractometer (XRD)
RINT2100, RINT2500 and SmartLab, Rigaku
4-axis X-ray Diffractometer (XRD)
RASA-7A, Rigaku
Thin Film X-ray Diffractometer (XRD)
X’Pert PRO MRD, PANalytical
Fourier Transform Ion Cyclotron Resonance Mass Spectrometer
(FT-ICR-MS)
26
Solarix-JA, Bruker Daltonics
Rutherford Backscattering Spectrometer (RBS)
NT-1700H, NHV Corp.
X-ray Photoelectron Spectrometer (XPS)
AXIS-ULTRA DLD, Shimadzu/Kratos
Electron Probe Microanalyzer (EPMA)
JXA-8900L, JEOL
Raman Spectrometer
T64000, HORIBA-JY
Physical Property Measurement System: Thermal Transport Option
PPMS-TTO, Quantum Design
Superconducting Quantum Interference Device Magnetometer(SQUID)
MPMS-5T and MPMS-7T, Quantum Design
Focused Ion Beam System (FIB)
SMI3050, SII NanoTechnology
Nuclear Magnetic Resonance Spectrometer: NMR 800MHz
Bruker BioSpin, Avance III 800
The NMR (Nuclear Magnetic Resonance)
machine detects FID (free induction decay),
which is the response to RF (radio frequency)
pulses applied to the nuclear spins set in the
strong magnetic field. NMR spectra obtained
by fourier-transformation of FID data give
information about molecular structures and
dynamics at atomic resolution. The NMR
machine with higher magnetic field can
provide better sensitivity and higher
resolution. This is one of the ultra-high field
NMR machines, on which 1H resonance
frequency is 800 MHz, installed at several
universities in Japan, and it is a very valuable
instrument. The strong magnetic field
enables a wide variety of advanced research.
JAIST also has other NMR machines which
can be used by many professors and
students for their own research.
(top) Two dimensional NMR (NOESY) spectrum of stomagen. (bottom)
1H-15N HSQC of stomagen, a peptide hormone to increase stomatal
density. Shinya Ohki, et al. Nat. Commun. (2011) 2, 51
1
H NMR spectrum focusing on the acetyl groups of poly(DHCA-co-4HCA)
Siqian Wang, et al. Ploym. Degrad. Stab. (2011) 96, 2048
27
Scanning Transmission Electron Microscope (Atomic Resolution):
STEM, JEOL, JEM-ARM200F
The TEM is an apparatus used to observe
and analyze microstructures of materials. The
ARM200F, incorporating a spherical
aberration corrector for electron optic system
as standard and the maximum level of
electrical and mechanical stability, has
achieved a scanning transmission image
(STEM-HAADF) resolution of 0.08 nm, the
highest in the world among commercial
transmission electron microscopes. The
electron probe, after its aberrations are
corrected, features a current density level
higher by an order of magnitude than
c o n v e n t i o n a l t r a n s m i s s i o n e l e c t ro n
microscopes. With this probe finely focused,
the ARM200F is capable of atomic level
analysis, substantially reducing measurement
time and improving throughput.
JAIST also has other TEMs which can be
used by many professors and students for
their own research.
TEM image of (Au@Ag3.6)@Au double shell NPs
Dao Thi Ngoc Anh, et al. Appl. Phys.
Lett. (2011) 99, 073107
28
EDS element mapping and plots of sulfur counts
along the cross section of devices
Varun Vohra, et al. J. Phys. Chem. Lett. (2012) 3, 1820
Cleanroom
The Center for Nano Materials and
Technology includes 6 Cleanrooms, which
are equipped with a vertical flow air-filtering
system to remove particles. These
cleanrooms, located on the 1st floor of the
C e n t e r, o f f e r c o n t r o l f u n c t i o n s f o r
temperature and humidity as well. Rooms 1-4
are Class 1000, Room 5 is Class 100, and
Room 6 is Class 10; only qualified researchers
are permitted to enter these rooms, and
special protective clothing is available. The
slightly higher air pressure in the cleanrooms
prevents possible contamination from
particles entering the rooms.
T h e s e c l e a n ro o m s c o n t a i n v e r s a t i l e
equipment for semiconductor process
research, to support university research in the
fields of microelectronics, electronic
m a t e r i a l s , n a n o t e c h n o l o g y, M E M S ,
lithography, optics, and other areas requiring
a particle-free environment. The special
lighting in the rooms is suited for precise
work with sensitive materials, and large
windows provide a comfortable, safe, and
convenient working environment.
Electron distribution and scattering in InAs films on low-k flexible substrates
Cong Thanh Nguyen, et al. Appl. Phys. Lett. (2012) 100, 232103
Tatsuya Shimoda, Japanese Patent
Application 2009-112455.
29
Features of the Educational System
Education Programs for a Variety of Study Objectives
In the rapidly evolving global work environment, JAIST offers a flexible education system so that you can achieve
your career goals. JAIST offers an educational program that can be tailored to fit your personal goals and
objectives, allowing a personalized education that will completely prepare you for your chosen career. JAIST also
offers a flexible registration system in support of students entering from the workforce, giving true flexibility to
your research and studies.
5 years
D Program
S Type
5D Program
E Type
3D Program
M Program
M Program
S Type
5D (5-year Doctoral) program is designed for those
who intend to pursue a doctoral degree from the outset
of their education. This is an integrated education
program from the master’s level through the doctoral
level. The completion of this program requires five years.
E Type
Possible to enter
the doctoral program
Career type (5D and 3D Program)
S (Scientist) Type : Those who wish to become creative
scientists
E (Engineer) Type : Those who wish to become highly
professional engineers
3D (3-year Doctoral) Program is a conventional
doctoral level education program with a special
emphasis on enhancing students’ practical and technical
skills. The completion of this program requires three
years.
M (Master’s) Program is a conventional master’s level
education program with a special emphasis on
enhancing students’ technical skills. The completion of
this program requires two years.
Supervisory System
At JAIST, students are guided through the education process
using a unique supervisory system. Each student is assigned three
advisors consisting of a supervisor, a second supervisor, and an
advisor for the minor research project. This structure provides
guidance and advice on the full range of education and research.
In addition, JAIST offers a career advisor system to give students
guidance and advice on general learning activities.
Student
Supervisor
Second
Supervisor
Advisor for the
Minor Research
Project / Internship
Study Materials Science in English
As a globally focused institute, one of the advantages of attending JAIST is that all of the doctoral courses are
taught in English. JAIST also offers the opportunity to obtain a master’s degree just by taking courses taught in
English. Both the master’s and the doctoral students are encouraged to prepare and present their thesis in English.
Polish Your Communication Skills / Critical Thinking Skills
We offer both English and Japanese language courses from introductory
level to business level taught by native speakers. JAIST offers courses to
develop key transferable skills such as critical thinking and communication
skills. These key strengths allow JAIST graduates to pursue a truly global
career.
30
Support System for International Students
International Student Section
JAIST is proud to offer a fully staffed International Student Section at the Student Affairs Department. Support staff
are not only friendly, but are also fully fluent in English. Our staff is happy to answer questions and support students’
everyday life. Check out the bilingual pamphlets published by the staff full of tips for your daily life in Japan.
We also organize Japanese cultural excursions, 3 times per year, and you can enjoy, for example, tea ceremony in
Kanazawa, together with Japanese students. They are also organizing a field trip for international students, once
per year, which is a one-day tour to a city such as Kyoto, Hida-Takayama, or Ise, where you can enjoy traditional
aspects of Japan.
Tutorial Service
Tutoring service is available for international students who have lived in Japan for less than a year. Tutors, who are
Japanese students in most cases, will accompany you and help you with your everyday life, such as starting gas in
the Student Housing, opens a bank account, or seeing medical doctors.
Career Counseling Supports
The Career Service Center in JAIST offers special support for international students who are seeking a job in
Japan. The Center provides job-related information about job postings, corporate seminars, and internships for
companies which are interested in hiring international students. Traveling expenses for going to internship or job
interviews in the Hokuriku region will be supported. Half of the examination fee for the Japanese-Language
Proficiency Test, the Business Japanese Proficiency Test, and the TOEIC test will be supported as well.
International Exchange Associations
You can also connect with the local community through organizations such as the Nomi International Friendship
Association. These organizations provide international people with a wide variety of information and
opportunities for getting to know each other.
31
Facilities for Students
Student Housing
Eight five-story Student Housing are located on campus.
International students receive priority to live in Student Housing.
Facilities:
Single room: Kitchenette and toilet,
Double and Family room: Kitchen, toilet, bathroom and laundry room.
PC can be connected to the campus LAN.
Library
The library at JAIST is administered based on the three principles of
“Open 24 hours a day“, “Research library“ and “Electronic library“. We
are confident that the quality of our library is appropriate for a graduate
school in terms of accessibility and the contents of its collection.
■Open 24 hours a day
Books and other materials can be viewed freely whenever it is necessary.
■Research library
Our collection is focused on academic materials that are highly professional and advanced.
■Electronic library
We are promoting a digital system of academic materials.
J-BEANS
“J-BEANS” is the Learning Commons and a place where students,
faculty and staff can study together and exchange academic ideas. The
room could be used for a group learning or for a presentation, etc.
Health Care Center
The Health Care Center located on campus provides general health care services, including health
examinations, first aid, health consultations and counseling, so that students and staff members can stay
healthy in mind and body. Regular check ups are provided for all students in April every year. Also, people
who work with X-rays can be specially examined, if necessary. The Health Care Center is furnished with beds,
massage chair, sphygmomanometer, scales etc. for use. It also provides the theater room equipped with high
quality sound and visual system. Students can use the room for self enjoyment. All these servises are free!
Facilities for Campus Life
Cafeteria and Cafe
A wide variety of dishes are available in a comfortable and relaxed atmosphere.
You can see the seasonal changes of nature through the windows.
Convenience Store: New Yamazaki Daily Store
Store hours
Lines of business
Monday-Friday 8:00AM-10:00PM.
Saturday, Sunday, Holidays 9:30AM-5:00PM.
Groceries, stationery supplies, magazines, home-delivery service,
dry-cleaning agent, etc.
Other Facilities
*International phone calls can be made from the public telephones.
*An ATM connected to major city banks on-line is located in the building.
32
Location
JAIST is in the center of the Ishikawa Science Park located on a hill in the city of Nomi in Ishikawa Prefecture. The
campus site enjoys scenic beauty, overlooking nearby counties and the city of Kanazawa to the north, the Sea of
Japan to the west, forests and pastures to the south, and the spectacular Mt.Hakusan to the east.
The area provides us with a variety of recreational facilities for every season, including several nearby ski resorts,
beaches and seaside parks, golf courses, hot springs and athletic and recreational parks. With a population
density far below that of the Pacific side of the island of Honshu, the area affords easy access to wilderness and
outdoor recreation.
Within 20km of JAIST is the historic city of Kanazawa, often referred to as the hidden gem of Japan, which hosts
numerous cultural events all year round.
CHITOSE
Air : 1 hour 35 minutes
SENDAI
Air : 1 hour
KANAZAWA
Air: 1 hour 5 minutes
Train : 2 hour 40 minutes
Train : 2 hours 20 minutes
FUKUOKA
Air : 1 hour 20 minutes
Train
Air
Train
JR
Komatsu
Station
Komatsu Airport
JAIST Shuttle（Komatsu Airport Line, Komatsu Station Line）
JAIST
Komatsu Airport ー JAIST 40 minutes
Komatsu Station ー JAIST 35 minutes
※If visitors will use the Shuttle（Komatsu Airport Line, JR Komatsu Station
Line）, reservations should be arranged for them by the JAIST faculty or
the departments with whom they are visiting.
JAIST Shuttle
Hokuriku Railroad
JR
Hokuriku Railroad （Tsurugi Line）
Local Train JR Nishi- Walk
Train
Ishikawa Line
Kanazawa
Kanazawa
Ishikawa Line
5 minutes
11 minutes
Station 4 minute Shin Nishi-Kanazawa 25 minutes Tsurugi Station
Station
Station
（190 yen）
（450 yen）
（Free）
JAIST
We operate the JAIST Shuttle Service free of charge to provide transportation
connecting JAIST with Komatsu International Airport, Japan Railway Komatsu
Station and Hokuriku Railroad Tsurugi Station.
33
National University Corporation
Japan Advanced Institute of Science and Technology
1-1 Asahidai, Nomi, Ishikawa, 923-1292, Japan
Phone: +81-761-51-1111 E-mail: ms-admin@jaist.ac.jp
http://www.jaist.ac.jp/ms/
[ YouTube ] http://www.youtube.com/JAISTClips
[ Facebook ] https://www.facebook.com/MaterialsScienceJAIST
[
Twitter
] https://twitter.com/jaist_ms_news
[
Flickr
] https://www.flickr.com/photos/jaist_ms_news/

Faculty Brochure

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