Winter 2008 - Sylvester Comprehensive Cancer Center
Transcription
Winter 2008 - Sylvester Comprehensive Cancer Center
Winter 2008 Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 Table of Contents 1 Message from the Director 2 S t o r y o f h o p e Pastry chef and cancer survivor Darleen Fenster shares her inspirational journey with cancer. Fenster was the first patient seen at UM/Sylvester in 1992. 5 e v e ry d ay h e r o After losing his father to cancer, Harcourt Sylvester Jr. vowed to fight back and chose Miami as the place to bring his vision of a cancer center to fruition. 9 M I L ESTONES A review of memorable moments and milestones that took place since the cancer center opened its doors 15 years ago. 11 O n t h e F r o n t L i n e Message from the Associate Directors; CoQ10 and skin cancer; Advances in skin cancer treatments; A better use of biopsies; A novel biological therapeutic agent shows promise; Catching melanoma early with dermoscopy; Primary Nursing Program improves patient safety; Advancing technology through UM Innovation; New recruits complement UM/Sylvester’s translational research efforts. 20 I n t h e N e w s Survey reveals disparities in skin cancer knowledge among high school students; A pain pioneer joins the Miller School of Medicine; ACS Institutional Research Grant awardees are announced; UM/Sylvester researcher receives prestigious appointment; Investigators are awarded a Leukemia and Lymphoma Society Award; Wolfson elected to board of renowned gynecologic oncology group; UM/Sylvester physician-scientist finds an inhibitor may prove beneficial in breast cancer therapy; Braman Family Breast Cancer Institute at UM/Sylvester announces grant awardees. 23 M a k i n g a D i f f e r e n c e Message from the Board Chair; Cancer survivors/advocates play the role of recruiters; Celebrations luncheon is reason to celebrate; Partygoers shopped for a cause at Key to the Cure; Firm finds synergy when partnering with UM/Sylvester; “Sunday Supper” takes philanthropy to a personal level; Four Seasons joins UM/Sylvester’s lifesaving mission; “Spot Out Cancer” event gains momentum; Pap Journal. On the cover: The cancer center’s namesake, Harcourt Sylvester Jr. 34 F a c t s a n d F i g u r e s UM/Sylvester’s financial and clinical profiles set new records. Our Mission We seek to reduce the human burden from cancer and other serious illnesses through research, education, prevention, and the delivery of quality patient care. Our Vision UM/Sylvester will become a fully integrated program of patient care, education, and research with an international reputation for excellence. UM/Sylvester will provide new hope for cancer patients in our extended community, which includes South Florida, the southeastern United States, the Caribbean, and South America. UM/Sylvester will promote efficient, community responsive health care, and generate resources to sustain and enhance innovative cancer programs. Our Values 10 Quest T h e M a g a z i n e o f t h eExcellence U n i v e r s i•t Compassion y o f M i a m i • SRespect y l v e s t e•rDiscovery Comprehensive Cancer Center Message From The Director M W. Jarrard Goodwin, M.D., F.A.C.S. “Mr. Sylvester and his family’s generosity continues to make a profound difference in our community. To date, the family foundation has committed more than $50 million to cancer programs at the University of Miami Leonard M. Miller School of Medicine, including many breakthrough initiatives at the cancer center.” ay 12, 2007 marked the 15th anniversary of the University of Miami Sylvester Comprehensive Cancer Center. UM/Sylvester’s record of achievement in research, education, and patient care has transformed cancer efforts in South Florida and beyond. All of this would not have been possible without the generous and visionary leadership of Harcourt Sylvester Jr., who passed away in August just a few months shy of our 15th anniversary celebration. Mr. Sylvester was an inspirational human being and a devoted philanthropist, and we miss him greatly. In 1986, under Mr. Sylvester’s leadership, the Harcourt M. and Virginia W. Sylvester Foundation committed $27.5 million to the University of Miami— the largest donation to the University at that time—to create South Florida’s only university-based cancer center. Six years later, UM/Sylvester officially opened its doors. Today, more than 200 physicians and scientists work together to realize Mr. Sylvester’s vision of a comprehensive cancer center, and thousands of patients each year receive lifesaving cancer care at locations in Miami and Deerfield Beach. Mr. Sylvester and his family’s generosity continues to make a profound difference in our community. To date, the family foundation has committed more than $50 million to support cancer programs at the University of Miami Leonard M. Miller School of Medicine, including many breakthrough initiatives at the cancer center. In this special annual report edition of Quest, we pay tribute to Mr. Sylvester and his family. This issue also contains news and updates on some of the exciting research taking place at the cancer center in melanoma and related skin cancers, one of 15 site disease groups at UM/Sylvester. In September, we submitted a cancer center support grant to the National Cancer Institute (NCI). If successful, this grant will provide approximately $1 million annually in support of our research infrastructure. Perhaps even more important, it would bring the NCI stamp of approval as an NCI designated cancer center. The standards for this review are very high. Success is not a given, but I am optimistic. In the Summer 2007 Quest, I also talked about the prospects of acquiring Cedars Medical Center. I am pleased to report that the University closed the deal December 1. Cedars has become the University of Miami Hospital. This is an immense opportunity for UM/Sylvester, and I could not be more enthusiastic about our future. Sincerely, W. Jarrard Goodwin, M.D., F.A.C.S. Sylvester Professor of Otolaryngology Director, UM/Sylvester Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 1 STOR y OF h o p e Friendships Forged: One Survivor’s Bittersweet Journey Darleen Fenster is a pastry chef, which might explain why she has such a sweet outlook on life, despite her cancer diagnosis 33 years ago. Fenster, in fact, would become the first patient to be seen at the University of Miami Sylvester Comprehensive Cancer Center. Her success story is truly inspirational. I n the spring of 1974, when Darleen Fenster was pregnant with her first son, she noticed a mole on the upper part of her right arm. “Strange things happen when you’re pregnant,” she thought. Not overly concerned, Fenster’s obstetrician removed the mole after the birth of her first son and reported back that it was benign. Then during her second pregnancy two years later, a new mole, a little larger than the size of a pencil eraser, grew through the scar. Fenster’s new obstetrician insisted she see a dermatologist. “I thought to myself, ‘I’ll go when I have time.’ I had a toddler and a brand new baby so it was difficult for me to take time away from them to go see a doctor,” she recalls. Months later, when visiting her child’s pediatrician, he too, noticed the growth, and asked her, “What’s that on your arm?” He urged her to get it checked out. So Fenster went to see a local dermatologist who removed the growth. The doctor called the next morning, and Fenster went to see him that same day. He told her it was melanoma and advised her to see a specialist to make sure the cancer had not spread. Without delay, her husband, Sandy, started making phone calls to find the best doctor to treat his wife. That person turned out to be Alfred Ketcham, M.D., who would later become chief of surgical oncology at UM/Sylvester. Ketcham, who was a faculty member at the University of Darleen Fenster visits with Dr. Fred Moffat 10 2 Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Left: Darleen Fenster is examined by Dr. Ketcham. Right: Nurse Barbara Sans (left) presents Fenster’s documents to fellow nurse Pam Carey (to left of Fenster) on the first day UM/Sylvester opened on May 12, 1992. This year, it is estimated that more than 8,000 people will die from melanoma, according to the American Cancer Society. The good news is, if diagnosed and treated early, melanoma is curable. Miami since 1974, first treated Fenster at Jackson Memorial Hospital. After examining the microscopic slide prepared from her biopsied tissue, reviewing her history, and checking the wound, Ketcham told her a wider area of the scar and skin had to be re-excised in order to remove any cancer cells that may have remained. “His motto was, ‘When in doubt, take it out’—when dealing with cancer,” recalls Fenster. When Ketcham reviewed the original microscopic slide from her first mole, he discovered she had been misdiagnosed the first time; it was indeed cancer. Ketcham’s supportive demeanor helped ease the young mother’s fears. “He treated me like his daughter. I was 28 and really scared; I was a brand new mom dealing with cancer,” she says. K etcham, who at 83 has been retired for ten years, vividly remembers the visit of this alarmed and anxious young couple. “Having had a history of this cancer growing back in the same area suggested she may have ‘fingers’ and ‘feelers’ of cancer cells extending into the tissue around the scar,” says Ketcham. He therefore re-operated and removed an area of tissue and underlying muscle and used a skin graft to cover the baseball-sized area on the arm. In addition to the surgery on her arm, lymph nodes from her armpit were surgically removed to ensure the cancer hadn’t spread through her bloodstream. It hadn’t. “She had minimal invasion, but we got the cancer before it became a problem.” Quest This year, it is estimated that more than 8,000 people will die from melanoma, according to the American Cancer Society. The good news is, if diagnosed and treated early, melanoma is curable. Fenster is one of those success stories. She says Ketcham was very compassionate with her. “He always walked in telling a joke and was never rushed. He’s such a wonderful man.” At the time Fenster was treated, UM/Sylvester hadn’t been built yet, but Fenster saw Ketcham at Jackson for follow-up visits weekly, then monthly, and then every three months, followed by every six months, and finally once a year. During those visits, Ketcham would run blood tests and examine her from head to toe, looking for anything suspicious. “I followed her carefully, and when the cancer center was ready to open its doors [in 1992], I asked her to be the first patient seen at UM/Sylvester,” says Ketcham. F enster still visits UM/Sylvester for her yearly checkups with Frederick L. Moffat Jr., M.D., professor of surgical oncology in the DeWitt Daughtry Family Department of Surgery at the University of Miami Leonard M. Miller School of Medicine, and a member of the Melanoma and Related Skin Cancers Site Disease Group at UM/Sylvester. Moffat had been one of Ketcham’s surgical fellows, undergoing several years of extra training in order to become a cancer specialist. During the time Ketcham treated Fenster, the two The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 3 STOR y OF h o p e became fast friends, staying in touch throughout the years. Darleen and Sandy would join Ketcham and his wife for dinner, frequent the theater, and even go out on family boat trips together. In fact, Ketcham attended both of Fenster’s sons’ bar mitzvahs—Brian, who is 33 today, in 1987, and Adam, who is 31, in 1989. Three years ago, Darleen and Sandy attended Ketcham’s 80th birthday party. Many surgical advances have been made at UM/Sylvester since Fenster was first treated. “We now have better management of how much tissue from around the area to take,” Moffat says. “We also have the option of a sentinel lymph node (SLN) biopsy, a new procedure that can be used on patients with early stage melanoma to find out if observation of the lymph nodes were the only options available.” A nother advance is immune stimulation, which in- volves administering a vaccine to “immunize” against cancer. This type of therapy holds special promise for melanoma patients. Researchers are experimenting with synthetic vaccines that when administered have been shown to evoke an immune response in some patients. Since treating Fenster, UM/Sylvester has witnessed phenomenal growth due to its ongoing recruitment effort. Fenster is proud to be part of that. In February 2006, she and Sandy hosted “A Sweet Celebration in Search Since treating Fenster, UM/Sylvester has witnessed phenomenal growth due to its ongoing recruitment effort and has contributed many pivotal scientific discoveries. for a Cure” in their home, which attracted more than 80 guests and netted $20,000 for surgical oncology research at UM/Sylvester. For Fenster, finding a cancer cure has been a very personal mission. Sadly, Sandy battled esophageal cancer for four years, losing his fight earlier this year. “It’s a fallacy that only old people get cancer,” she says. “Life is short; every day is a gift. You have to enjoy every moment and make the most out of every single year. My husband and I lived that way every day of our lives.” It’s a motto she hopes others will follow. “That’s what having cancer at 28 does to you. You realize life is not a dress rehearsal. Enjoy it while you’re here!” F Fenster, right, visits Dr. Alfred Ketcham and his wife, Jane, in Sodus Point, New York. it has spread to the nodes.” Cancer usually spreads from the tumor to the SLN before invading the other lymph nodes. Through a SLN biopsy, doctors remove the SLN and analyze it to see if cancer cells are present. “This is a major change,” says Moffat. “When Mrs. Fenster was treated [in the late 1970s], we didn’t have this technique. Radical lymph node surgery or simple 10 4 Quest enster currently is pursuing her passion for cooking and has set her sights on traveling abroad. She recently spent one week in the Tuscany region of Italy to attend culinary classes. “Baking is my passion—what you do in life has to be your passion,” she says. Her job as a pastry chef, along with her sweet culinary creations, allows her to share happiness with others. “There’s no better feeling than making others happy on joyous occasions by creating something that tastes as good as it looks.” Today, Fenster is glad to be healthy and is thankful to UM/Sylvester, a place where she developed strong bonds over the years. She just celebrated her 59th birthday with her beautiful family: her son Brian and his wife Shelevah; their daughters Telem and Keren; and her son Adam and his wife Goldie. “I love birthdays. I’m just so happy to be here,” she says. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center e v e ry d ay h e r o Building a Legacy After losing his father to cancer in the 1980s, Harcourt Sylvester Jr. vowed to fight the disease. He dreamed of a university-based cancer center and pledged millions of dollars to launch the University of Miami Sylvester Comprehensive Cancer Center, which opened in 1992. He remained active with the organization for 15 years, until his death in August 2007. His pledge became a family mission, and now his daughters and grandchildren will continue his legacy. For Harcourt Sylvester Jr., ucts. Mr. Sylvester joined the fam- cancer hit extremely close to home. ily business after graduating from His father, Harcourt M. Sylvester Florida Southern College. Eventu- Sr., battled lung cancer, succumb- ally, he became president and CEO. ing to the disease in 1980. After his The company was sold in 1980. As a South Florida resident, it father’s death, the Harcourt M. and was only natural that he chose Miami Virginia W. Sylvester Foundation was established. Harcourt Sylvester Jr. The Sylvester family, originally from Rochester, as the place to bring his vision of a cancer center to fruition. Mr. Sylvester admired the New York, relocated their family business, Fasco Indus- University of Miami School of Medicine’s reputation, tries, to Boca Raton, Florida in 1974. The company so in 1986, after a few phone calls, he decided to lend designed, manufactured, and sold a variety of electri- his support, overseeing the Foundation’s commitment cal products such as fractional horse power motors for of $27.5 million to build South Florida’s sole university- use by manufacturers in consumer and business prod- based cancer center. It was the largest gift to the Univer- Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 5 e v e ry d ay h e r o sity of Miami at the time. M.D., F.A.C.C., senior vice president In addition to lending financial support, Mr. Sylvester was committed to being hands on with the for medical affairs and dean of the Miller School of Medicine. On May 12, 1992, the com- building of UM/Sylvester, attending prehensive cancer center became a meetings with architects and con- reality, opening its doors to patients tributing to the design of the center. in need of specialized cancer care. “He studied everything to ensure Fifteen years later, the cancer cen- the patient experience would be as ter continues to pioneer efforts in soothing as humanly possible,” re- cancer research, diagnosis, and treat- calls Bernard J. Fogel, M.D., dean ment. Today, more emeritus of the University of Miami than 200 physi- Leonard M. Miller School of Medi- cians and scientists cine. He was deeply devoted not only work at the cancer to creating a state-of-the-art cancer center, which sees center, but also one that kept the 3,400 new can- patients’ needs in mind. “He was pas- cer cases annually sionate both about finding cures for and reports close cancers and about the comfort of the to 200,000 outpatient visits. “We’re Top: Harcourt Sylvester Jr. speaking on the day of the patients,” says Pascal J. Goldschmidt, making great strides in research and dedication in 1992. Middle: From left to right: Dean bringing that research to the bed- Emeritus Dr. Bernard J. Fogel, Laura S. Cameron, Jayne S. side,” says Jayne Malfitano, daughter Malfitano, former University of Miami President Edward of the late philanthropist. T. Foote II, Harcourt Sylvester Jr., and Jose Cancela. UM/Sylvester Director W. Jar- Below: A view of UM/Sylvester from the courtyard. rard Goodwin, M.D., F.A.C.S., says Mr. Sylvester never asked man, and he did extraordinary things for anything, just that the but never lost the common touch, cancer center leadership do and he cared about all people. I assure their best. He adds that Mr. you, we are resolute in our promise to Sylvester’s dignity and passion carry out his vision,” says Goodwin. for bringing hope to cancer 10 6 Quest Loved ones recall how he would patients was inspirational. tell them how inspired he was by in- “Court was an important teracting with those at UM/Sylvester. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center In addition to lending financial support, Mr. Sylvester was committed to being hands on with the building of UM/Sylvester, attending meetings with architects and contributing to the design of the center. thank him for his lifesav- the creation of a cancer research floor ing efforts, yet he always in the University of Miami’s Batchelor remained humble. “He Children’s Research Institute, which was shy and a private was dedicated in 2001. In 2003, Mr. person, but Dad loved to Sylvester, joined by his daughters Jayne go there [UM/Sylvester],” Malfitano and Laura Cameron, com- says Malfitano. memorated the opening of UM/Sylves- In 1996, Mr. Sylvester, in collaboration with the United Way of Palm Beach County and Children ter at Deerfield Beach, which currently is expanding to double its size. Both Malfitano and Cameron are Services Council, established the Syl- actively involved with UM/Sylvester vester HIV/AIDS Prevention Fund. In and continue to carry the torch for addition to its contributions to fight their father. Malfitano serves on the cancer, the Sylvester Foundation was UM/Sylvester Board of Governors and the first million-dollar donor to the also sits on its marketing and board United Way of Palm Beach County. services committees. She also is active Top: From left to right: Edward T. Foote II, former Numerous organizations benefited on the University of Miami Board of president of the University of Miami, Laura S. Cameron, from Mr. Sylvester’s generosity. They Trustees. Both sisters serve as directors Harcourt Sylvester Jr., Jayne S. Malfitano, and Dean include: the Children’s Place at Home of the family’s foundation which to Emeritus Dr. Bernard J. Fogel, presenting the portrait Safe, Drug Free America, The Gulf date has contributed or pledged more of Harcourt Sylvester’s mother, Virginia W. Sylvester, Stream School, the Juvenile Diabe- than $50 million to Miller School of currently displayed at UM/Sylvester. tes Research Foundation, the Lord’s Medicine programs. “We have such Bottom: Harcourt Sylvester Jr., (left) and Charles Place/Café Joshua, and the National respect for the cancer center and are Gordon Zubrod, M.D., (right) former director and chair- Parkinson Foundation. so proud of it. For Laura and I, it’s man of the Department of Oncology at UM/Sylvester Throughout his life, he remained second nature. How can we not be in- steadfast in his generosity. When volved?” says Malfitano. Mr. Sylves- Yet he, too, was a source of inspira- touched by cancer yet again when one ter’s grandson, 20-year-old Jeffrey, is tion. Fogel remembers him being of his grandchildren was diagnosed, Mr. a member of the fundraising group, overwhelmed by patients who would Sylvester was moved to action, funding Young Philanthropists for Sylvester, Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 7 e v e ry d ay h e r o “If we love, if we hope, if we help one another, if we help the less fortunate… we will exceed our fondest expectations. May hope run eternal in us all.” —Harcourt Sylvester Jr. and granddaughter Jena, a University Achievement Award, and the Univer- of Miami graduate, used to accompa- sity of Miami Dean’s Award. ny her mom, Laura, and grandfather Harcourt Sylvester Jr. was born to the galas, where she often served as in 1927, and passed away on August his date. “He loved that and got a big 10, 2007 at age 80. He is preceded in kick out of it,” says Cameron. “Each death by his son, Steven, and is sur- of the grandkids is finding their way vived by his two daughters, Jayne and to give back.” Mr. Sylvester served as a trustee Award, the Sun-Sentinel Publisher’s Laura, ten grandchildren, and two Award for exemplary service and lead- great grandchildren. emeritus of the University of Miami ership, and the United Way of Palm and received numerous awards in his Beach County’s Alexis de Tocqueville one another, if we help the less fortu- lifetime, including Café Joshua’s Edna Society Leadership Award. Others nate… we will exceed our fondest ex- Hibel Award for commitment to end included the Countess de Hoernle pectations,” said Mr. Sylvester when homelessness in Palm Beach County, Humanitarian Award, the Palm Beach UM/Sylvester first opened its doors. the JC Penney Volunteer of the Year Chamber of Commerce Charitable “May hope run eternal in us all.” “If we love, if we hope, if we help Survivors’ Day 2007 Takes on Special Meaning U M/Sylvester welcomed nearly 600 guests, including more than 260 cancer survivors, along with their loved ones, in an unforgettable evening of celebration and tribute in early November. Not only were these brave individuals honored for their courage and strength, but a heartfelt tribute also went out to Harcourt Sylvester Jr., whose lifesaving vision led to the creation of the cancer center 15 years ago. In fact, 2007 marks the 15-year anniversary of UM/Sylvester, South Florida’s only university-based cancer center, where world-class physicians and researchers work diligently every day to treat cancer patients and find a cure for the devastating disease. The special night of celebration included a reception, dinner, stories of survival, and anniversary mementos. Also on hand was cancer survivor Darleen Fenster, who was the first patient seen at UM/Sylvester in 1992, as well 10 8 Quest as Willowstine Lawson, a representative from the office of Darleen Fenster (center), with her son Adam Fenster the Honorable U.S. Senator Bill Nelson. (left), and Dr. Jerry Goodwin (right) The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Milestones UM/Sylvester Celebrates 15 Years S ince opening its doors in 1992, the University of Miami Sylvester Comprehensive Cancer During the past 15 years, UM/Sylvester has earned the respect of the international cancer community and Center has enjoyed a has emerged as a magnet for number of memorable moments today’s leading cancer experts. and milestones, including the Now, this diverse team of cancer center’s 15th anniversary. physician-scientists works to This special milestone was made develop cancer breakthroughs all the more poignant by the in the laboratory and apply news in August of the death of the center’s namesake, Harcourt Sylvester Jr., whose generosity and those breakthroughs to save From left to right: Dr. Jerry Goodwin; Dr. Luis Glaser, former provost of the University of Miami; Harcourt patients’ lives every day. Sylvester Jr.; and Dr. Bernard Fogel, dean emeritus drive founded the center. 1992 The Sylvester ship to the hospital. dia industry, becomes chair Comprehensive Cancer The hospital’s of the Board of Governors. Center, made possible Board of Governors by a $27.5 million dona- is strengthened 2001 Joseph D. Rosen- tion by Harcourt Sylvester Jr. on behalf of by the addition of community leaders inter- the Harcourt M. and Virginia W. Sylvester ested in cancer. Foundation, opens its doors. At the time, the 1995 The Courtelis Center 117,500 square-foot center was the largest outpatient cancer treatment facility in the southeastern United States. blatt, M.D., is recruited to UM/Sylvester. Rosenblatt serves as associate director of clinical and transla- for Research and Treatment tional research and chief in Psychosocial Oncology is of the Division of Hematol- founded. University of Miami ogy-Oncology. Jay Weiss becomes chair of the UM/Sylves- Board of Trustees member ter Board of Governors. Known for his com- and cancer patient Alec passion and generosity, Weiss helped raise Courtelis and Sharlene Weiss, Ph.D., a volun- more than $150 million for the University of tary faculty member in UM/Sylvester’s Biobe- Miami and led UM/Sylvester during some of havioral Oncology and Cancer Epidemiology its most challenging years. He passed away Program, provide the inspiration in January 2004. and lead fundraising efforts. Joyce M. Slingerland, M.D., 1993 W. Jarrard Goodwin, M.D., F.A.C.S., 2000 Joaquin F. Blaya, recog- Ph.D., F.R.C.P.(C), is recruited and David Stansberry, former hospital ad- nized as one of the most influen- ministrator at UM/Sylvester, are recruited to tial Hispanic businessmen in the provide faculty and administrative leader- country and a legend in the me- Quest 2002 Miami Beach philanthropists Irma and Norman Braman announce a $5 million gift to help establish the Braman Family Breast Cancer Institute at UM/Sylvester. to direct the Braman Family Breast Cancer Institute at UM/Sylvester. In 2006 she receives a five-year $1.5 mil- The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 9 Milestones lion Doris Duke Distinguished Clinical Scien- Selevan Fromberg in memory of her step- Department of Medicine at tist Award to support her work investigating daughter Jill Selevan, who passed away Duke University Medical how estrogen affects p27, a vital tumor cell from cancer in her late 30s. The non-denomi- Center. regulator. national chapel offers an inviting place for 2003 UM/Sylvester at Deerfield Beach, a prayer, reflection, and services. 2007 Joan Scheiner becomes chair of the Board 10,000-square-foot facility designed to bet- of Governors. Scheiner, a ter meet the needs of residents of Broward cancer survivor herself, and Palm Beach Counties, opens. Deerfield also is a Grand Founder of Beach offers appoint- UM/Sylvester, a member ments with physicians of the Founders Society, from 12 of UM/Sylvester’s chair of the Development 15 site disease groups, Committee, and co-chair complementary therapies of the $137 million capital from the Courtelis Center, campaign. and education and outreach events. 2004 UM/Sylvester launches a $137 million capital campaign as part of the University of Miami’s $1 billion Momentum Campaign. The University of Miami School of Medicine receives a $100 million gift from the family David Stansberry retires 2006 UM/Sylvester and the Diabetes Research Institute Foundation jointly receive a $35.6 million gift from the estate of the late Eugenia J. Dodson. The gift creates two endowed Dodson Chairs in Cancer Research at UM/Sylvester. after serving 15 years at the University of Miami and UM/Sylvester. As hospital administrator, he was responsible for many dramatic improvements at UM/Sylvester. Stansberry of the late Leonard M. Miller, a longtime is succeeded by Michael South Florida businessman and philanthro- Gittelman. pist. In recognition of Michael Gittelman is the gift, the School of named administrator for Medicine is renamed the University of Miami the University of Miami Specialty Hospitals, which Leonard M. Miller School include UMHC and Bascom of Medicine. Palmer/Anne Bates Leach 2005 Ground is broken Eye Hospital, where he has served as administrator on the new Clinical Research Building, which today stands 16 stories tall and houses various research and clinical departments on the Miller School of Medicine campus. The Jill Selevan Chapel, just off the UMHC lobby, is dedicated. Funding for the project was graciously donated by Doree 10 Quest The Papanicolaou Corps for Cancer Research announces a record-breaking gift of $3.325 million to fund cancer research at UM/Sylvester. The gift brings the total raised by the Pap Corps over the past four years to since 2004. Harcourt Sylvester Jr. passes away at the age of 80. nearly $11 million, which exceeds their initial University leadership five-year pledge made in 2003 of $10 million. purchases Cedars Medical Pascal J. Goldschmidt, M.D., F.A.C.C., becomes senior vice president for medical affairs and dean of the Miller School of Medicine. He is the former chairman of the Center, which will provide 560 additional beds, full service hospital capabilities, and private rooms for all patients. It becomes the University of Miami Hospital. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center On The Front Line M e s s a g e f r o m t h e A s s o c i at e D i r e c t o r s T hanks to growing support from the National Cancer Institute (NCI), the South Florida community, and the State of Florida, the University of Miami Sylvester Comprehensive Cancer Center’s cancer center support grant was submitted as scheduled to the NCI in September. The grant describes the exciting growth we are experiencing such as the many newly recruited cancer-focused physicians and scientists now on board. It also describes the expansion of research and clinical facilities at the medical campus as well as at our regional satellites and collaborating institutions. In addition, Glen N. Barber, Ph.D. Associate Director Basic Science the grant details UM/Sylvester’s unique extended community and its importance to the nation’s cancer research efforts. Since much of the United States is expected to gradually resemble South Florida’s population mix, UM/Sylvester’s environment represents an important “population laboratory” for the nation’s cancer research efforts. UM/Sylvester’s cancer focus is most evident in the structure and accomplishments of its multidisciplinary research programs. Two of these programs, Viral Oncology and Biobehavorial Oncology and Cancer Epidemiology, were developed to address the unique medical needs of our diverse community. The Jennifer J. Hu, Ph.D. Associate Director Cancer Prevention and Control two remaining programs, Tumor Immunobiology and Immunotherapy and Molecular Targets and Developmental Therapeutics, have developed around long-standing institutional strengths. All four programs are translational in nature—which means that UM/Sylvester physicians have the unique ability to apply research breakthroughs from the laboratory to the patient’s bedside. In this environment, physicians are able to closely evaluate the effectiveness of new treatments and share clinical insights with laboratory investigators, which leads to improvements in patient care. Translation has been further assisted by the launch of the Phase I Drug Development Program, which was created to Robert S. Powell, M.Ed. Associate Director Administration better bridge the gap between laboratory breakthroughs and clinical applications in the form of improved access to new cancer treatment approaches. This Continued on next page Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 11 On The Front Line is the only Phase I Drug Development Program in the region. UM/Sylvester investigators also are developing an extensive portfolio of research projects aimed at understanding cancer disparities in Miami-Dade County and addressing these disparities as they are identified by our researchers. Our world-class multidisciplinary efforts in lymphoma, breast cancer, Joseph D. Rosenblatt, M.D. gastrointestinal cancer, lung cancer, and head and neck cancer highlight our pivotal development and integration of new biologic agents into the medical Associate Director Clinical and Translational arsenal. These include agents developed at UM/Sylvester such as gene therapy, Research antibody fusion proteins, viral therapies, new antibodies, as well as drugs and drug combinations pioneered here. We also continue to recruit physicians and scientists in many key areas, including radiation oncology and pathology. We are excited about the initiatives already in place and the enormous opportunities that lie ahead in the areas of prevention and treatment of cancer. The last 15 years have brought great promise in the area of cancer research, and today UM/Sylvester is the preeminent cancer center in this community, in South Florida and beyond, and a resource for the Caribbean basin and Latin America. Sean P. Scully, M.D., Ph.D. We salute the efforts of our physician-scientists, board members, generous sup- Associate Director Education and Training porters, and patients in our mission to provide world-class cancer care. Sincerely, Glen N. Barber, Ph.D. Jennifer J. Hu, Ph.D. Robert S. Powell, M.Ed Joseph D. Rosenblatt, M.D. Sean P. Scully, M.D., Ph.D. 10 12 Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Novel Biological Therapeutic Agent Shows Promise S cientists at UM/Sylvester are leading efforts in skin cancer research to look for better ways to prevent, diagnose, and treat non-melanoma and melanoma cancers. Among their current focuses: an exciting new targeted therapy aimed at saving the lives of melanoma patients. UM/Sylvester researchers conducting a Phase II trial are seeing early, but very promising results from treating melanoma patients with ADI-PEG, a novel biological therapeutic agent. “ADI-PEG is an anti-cancer enzyme that depletes the amino acid arginine from the blood. While normal human cells are able to synthesize arginine, some cancer cells, such as melanoma, are deficient in the necessary enzymatic pathway for arginine synthesis,” says the study’s principal investigator Lynn G. Feun, M.D., co-leader of the Melanoma and Related Skin Cancers Site Disease Group at UM/Sylvester and professor of medicine at the University of Miami Leonard M. Miller School of Medicine. “Therefore, depleting arginine from the blood can control tumor growth and even eliminate argininerequiring cancers without damage to normal cells.” UM/Sylvester’s promising ADIPEG melanoma trial results are prompting other major cancer research centers to look into the role of this therapeutic agent. “Memorial Sloan Kettering and New York University are starting clinical trials in melanoma to confirm our data,” Feun says. Although this National Institutes of Health-funded trial is ongoing, Feun says that he has observed “major” responses in patients with advanced Quest melanoma—even among those who have not responded to other therapies. He adds that UM/Sylvester researchers are working on this drug in the laboratory to discover which melanoma patients may benefit from and how best to use the drug in combination with other cancer treatments. “This trial is important because melanoma is an increasing problem. ADI-PEG is a targeted therapy that can spare normal tissue and does not have the side effects of chemotherapy and other less targeted adjuvant treatments,” he says. Lynn G. Feun, M.D. CoQ10 cream to mice with melanoma tumors, they could reduce tumor mass by more than half. In fact, these laboratory animal studies suggested that topical CoQ10 could induce apoptosis, which is the normal programmed cell death that goes awry in cancer. Armed with this promising research, UM/Sylvester has taken a leading role in CoQ10 with studies aimed at understanding the mechaCoQ10 and skin Cancer nisms of how CoQ10 works; underreliminary data from UM/Syl- standing whether the full molecule vester research suggest that the or any individual component is antioxidant coenzyme Q10 (CoQ10) responsible for the observed effects; might play an important role in skin optimizing the delivery of CoQ10 cancer treatment and prevention, ac- treatment; and studying the usefulcording to Robert S. Kirsner, M.D., ness of this medication in a variety Ph.D., a member of the Biobehavioral of cancers, says Kirsner. CoQ10 was Oncology and Cancer developed by Kirsner’s Epidemiology Procolleagues S.L. Hsia, gram at UM/Sylvester Ph.D., Niven Narand professor and vice ian, and Indushekar chair in the DepartPersaud. Both Narian ment of Dermatoland Persaud continue ogy and Cutaneous to work on it. Surgery at the Miller K i r s n e r, w h o School of Medicine. is super vising the UM/Sylvester reCoQ10 research, searchers have found s a y s t h a t w h i l e that when applying Robert S. Kirsner, M.D., Ph.D. U M / Sy l v e s t e r re - P The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 13 On The Front Line searchers are not yet ready to report their results, the hope is that CoQ10 will be a therapeutic advance for the millions of Americans who suffer from skin cancer. “We also hope that a better understanding of CoQ10 and its role Keyvan Nouri, M.D. in cell growth will provide insight into new treatment options for all kinds of skin conditions, including skin cancer,” Kirsner says. UM/Sylvester has proprietary rights to a delivery system for CoQ10, which the University has licensed to a company interested in pursuing CoQ10 as a potential treatment. “This collaboration has put the cancer center in a position to further study and make unique insights into CoQ10 and cancer treatment,” says Kirsner. Advances in Skin Cancer Treatments he gold standard treatments for nonmelanoma skin cancers remain simple excision and Mohs micrographic surgery,” says Keyvan Nouri, M.D., a member of the Melanoma and Related Skin Cancers Site Disease Group at UM/Sylvester and professor of dermatology and director of dermatologic surgery at the Miller School of Medicine. The Mohs procedure involves removing skin cancer one layer at a time and examining these layers under a microscope. Mohs surgeons keep removing tissue until the margins are cancer free. The approach, Nouri says, allows surgeons to remove the whole tumor to cure the cancer but leave as T little a cosmetic scar as possible. Today, however, there are many other options, including studies looking at alternative treatments, such as light sources and topical creams that boost the immune system. While laser treatments have not been shown to be particularly successful in removing skin cancers, light therapy, specifically photodynamic therapy (PDT), does have a place in skin cancer treatment, Nouri says. Melanoma as seen “ P D T i n - through a dermoscope. volves using a photosensitizer, called aminolevulinic acid (ALA) in combination with a blue, red, or other light source,” Nouri says. “We apply the photosensitizer to Understanding Skin Cancer C ancer that forms in tissues of the skin accounts for on the body, including areas that are not sun-exposed, such nearly half of all cancers in the United States, accord- as on the bottom of the feet. Other less common skin cancer ing to the American Cancer Society. In fact, with more types include: than one million skin cancers diagnosed each year, the number Kaposi’s sarcoma, which most often develops in associa- surpasses diagnoses for prostate, breast, lung, colon, uterine, tion with human immunodeficiency virus (HIV) infection and ovarian, and pancreatic cancers combined. the acquired immunodeficiency syndrome (AIDS). This type There are many different types of skin cancer. The most of cancer typically results in tumors developing in the tissues common are non-melanoma basal cell and squamous cell below the skin’s surface or in the mucous membranes of the carcinomas. Basal cell skin cancer forms in the basal cells, mouth, nose, or anus. Kaposi’s sarcoma, which is usually not or the small, round cells in the base of the outer layer of skin. deadly but can be disfiguring, has become far less common Squamous cell carcinoma occurs in squamous cells, the flat thanks to new and better treatments for AIDS and HIV. cells that form on the skin’s surface. Both of these skin can- Paget’s disease is a form of breast cancer where the cers are sun-related, most often occurring on sun-exposed tumor grows from ducts beneath the nipple onto the surface areas of the body. of the nipple. This type of cancer also can affect other skin Melanoma, the most deadly of skin cancers, forms in cells that make pigment. Caught early, melanoma is highly 10 14 areas, such as the perianal area and vulva. (Paget’s disease of the bone is a different disease.) curable. However, once the cancer thickens, it is much more Merkel cell cancer is a rare skin cancer developing in the difficult to treat successfully. Melanoma can occur anywhere skin’s hormone-producing cells. Merkel cell cancer usually oc- Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center the skin and leave it on for a few hours for the cancer cells to absorb. We then shine the light source on the area to activate the porphyrin (an organic compound that binds metals), which destroys the cancer cells.” Other options in the treatment of less aggressive basal cell carcinoma include in-office procedures such as scraping, burning, or freezing. For some squamous cell lesions, surgical excision is a less invasive alternative to Mohs. New treatments for these two non-melanoma skin cancers include the use of a topical cream, called Aldara (imiquimod), an immune modulator that stimulates the body’s immune system to get rid of the cancer. “Aldara has been FDA-approved for pre-cancers, called actinic keratosis, and superficial forms of basal cell carcinoma,” he says. “The approaches for melanoma, the deadliest of skin cancers, are not so clear cut,” says Nouri. “The problem is that often the cancer is not diagnosed in its earliest, most treatable, stages,” he says. “Melanoma can be cured if detected early.” Catching Melanoma Early with Dermoscopy lthough widely used in Europe, UM/Sylvester is one of just a few U.S. cancer centers using dermos- A Johr also uses the Molemax A dermoscope used to diagnose machine, right, to view detailed melanoma. microscopic images of moles. curs in sun-exposed areas ingly, Sun Belt states, including Florida and California, report and is often more aggressive the highest incidences of melanoma in the United States. than basal cell and squamous And the more sunlight in the day, the greater the incidence of cell carcinomas. Merkel cell the non-melanoma skin cancers, so Arizona, Texas, and Florida— skin cancer can return after states closer to the equator—have higher rates of these other treatment—even spreading skin cancers, according to the Skin Cancer Foundation. to the internal organs. Cutaneous T-cell lym- Typical melanoma copy and digital dermoscopy, technology that helps physicians diagnose melanoma early. According to recent research published in the Archives of Dermatology, digital dermoscopy has been shown to be a lifesaving technology for melanoma patients, says Robert Johr, M.D., director of UM/Sylvester’s Pigmented Lesion Clinic and clinical professor of dermatology at the Miller School of Medicine. “The researchers in this study, from Vienna and Australia, took digital dermoscopic images of subjects’ moles and they followed them over time to see if the moles changed. They did 499 comparisons of baseline digital dermoscopic images Although skin cancers are most prevalent among adults who have had accumulated sun exposure, melanoma can oc- phoma is the most common cur among children. According to the Skin Cancer Foundation, type of primary cutaneous children under the age of six months should not be exposed lymphoma, which is a type to the sun at all. of lymphoma that appears to start predominately or entirely in the skin. The key with skin cancer, as with other cancers, is to catch it early, when it is highly curable. In addition to using sun-protection, see a dermatologist once a year for a full-body What You Can Do T skin exam. Get to know your skin and any moles or lesions you he sun’s ultraviolet B (UVB) rays are thought to be the most might have. Examine your skin monthly for any changes. These responsible for skin cancers although recent research changes include new moles or spots, as well as areas that may suggests that UVA rays also might be to blame. Not surpris- Quest have changed in texture, shape, color, or size. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 15 On The Front Line and follow-up images and found changes in many lesions. Ninety melanomas were found this way; half of the melanomas were 100 percent curable and the other half were found early enough for a good chance for cure,” Johr says. One of the important observations of this study, according to Johr, was that many of the melanomas that were removed did not look like melanomas, clinically, or with dermoscopy. Only because the lesions were found to change over time, excisions were performed and the melanomas were diagnosed. This same technology is used at UM/Sylvester’s Pigmented Lesion Clinic. The next step toward improving melanoma diagnosis is pending FDA approval. Johr is keeping an eye on a handheld device called MelaFind® that uses visible and infrared light to capture images of suspicious ogy reported that only 25 percent of pigmented skin lesions and diagnose dermatologists use dermoscopy and them automatically. The ability of very few use digital dermoscopy. MelaFind® to accurately diagnose “For a cutting edge skin exmelanoma better than experienced amination, dermoscopy should dermatologists looks be used not only to promising. examine suspicious “For now, the best skin lesions but also way to detect melanoones that might look ma and other forms of okay, because up to skin cancer is by havten percent of melaing an annual headnomas do not look to-toe skin exam with like melanoma. They your dermatologist. are called melanoma Eighty percent of melincognito and are esanomas are on areas George W. Elgart, M.D. pecially hard to diagof the body that are nose,” Johr says. covered by clothes, so it is essential to find a doctor who does total body Better Use of Biopsies skin examinations. Unfortunately, a M/Sylvester’s George W. Elgart, significant number do not,” he says. M.D., co-leader of the MelaAccording to Johr, the Journal of noma and Related Skin Cancers Site the American Academy of Dermatol- Disease Group and professor and vice chair of the Department of Dermatology and Cutaneous Surgery at the Miller School of Medicine, is workPrimary Nursing Program improves patient safety ing on several methods to extract he UM/Sylvester Head and Neck Clinic is piloting a Primary Nursing Program usable information from melanoma designed to improve the quality and safety of patient care. biopsy specimens. When physicians Launched in April, the program pairs individual nurses and physicians with biopsy a lesion to determine if it is patients so that they see and interact with the same nurse at every visit. Over the melanoma, he explains, they do not course of treatment that nurse remains the primary contact for the patient. always take the entire lesion on the “With this program, patients always communicate with the same nurse,” says original biopsy. Elizabeth Smith, R.N., B.P.S., director of nursing services at UM/Sylvester, who serves “Since tumor depth directly as director of the program and helped develop the curriculum. affects staging of the disease, it is “The program provides for increased continuity of care and improved patient important to handle those ‘incomsafety and outcomes. Compliance with treatment protocols may be enhanced with plete’ specimens carefully to obtain better communication between patient and caregiver,” adds Smith. “This has been the most information possible from a joint effort among the nursing leadership, and we are excited to see it come to the specimen,” Elgart says. “We are fruition.” studying our cases with the hope of “So far the program has been a great success,” notes Penny Fisher, M.S., R.N., finding new ways to get useful inforC.O.R.L.N., advanced practice nurse and clinical instructor of otolaryngology at the mation from them. This could help Miller School of Medicine. Fisher serves as a teacher and mentor for the program. in the staging of cases of melanoma To date, four primary nurses are managing the care of the patients of seven and may help to guide clinicians to physicians. The program will be expanded to other clinics and units throughout the make the best decisions for patients cancer center in the near future. with this disease.” U T 10 16 Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Advancing Technology Through Innovation U M Innovation is the home of technology advancement at the University of Miami and serves to integrate the University of Miami’s vibrant and comprehensive research initiatives. As a focal point for technology development and commercialization opportunities, UM Innovation serves as a bridge between faculty physicians and scientists seeking to commercially Above: Norma Kenyon, M.D., translate their research efforts and cor- director of the Wallace H. Coulter Center for Translational Research; porate entities interested in accessing Gary Margules, Sc.D., assistant and advancing innovative technologies. By working with UM/Sylvester in managing the intellectual property process and commercialization of its discoveries, UM Innovation may help UM/Sylvester to generate income through royalty and/or licensing revenue. Such translation successes may generate philanthropic and industry support and augment faculty recruitment. “This is a prime example of why it is so valuable for UM/Sylvester to be an integral part of a dynamic research university,” says W. Jarrard Goodwin, M.D., F.A.C.S., UM/Sylvester’s Director. UM Innovation integrates the University’s Office of Technology Transfer, the Wallace H. Coulter Center for Translational Research, the future University of Miami Life Science Park, and the Patent and Copyright Committee. As such, UM Innovation provides a convenient, efficient, and user-friendly thruway for corporations seeking to license basic research, applied research, and patents, and provides for collaborative opportunities with University faculty scientists. Quest vice provost and director, Office of Technology Transfer (OTT); and Keith Rubin, M.D., deputy director of special programs in bioscience and assistant professor of clinical medicine. Left: From left to right: Bart Chernow; Gary Margules, Sc.D.; Bin Yan, Ph.D., LL.B., director of business development, Coulter Center; and Keith Rubin, M.D. Within the University community, faculty, staff, and student entrepreneurs can access UM Innovation to frame their scientific and business goals, write business plans, raise capital, and interface with an experienced and ready, willing, and able team, led by Bart Chernow, M.D., M.A.C.P., vice provost of technology advancement for the University of Miami. To expand the pioneering research initiatives across the University, UM Innovation also has been conceiving and developing plans for a University of Miami Life Science Park where future basic science, applied research, and commercial collaboration will intersect. The Life Science Park will extend the University’s rigorous quest for knowl- edge to find new ways to understand, diagnose, and treat disease, and also will welcome all aspects of the life sciences. With up to 1.4 million square feet of space and situated on approximately seven acres adjacent to the Miller School of Medicine, the University of Miami Life Science Park will become a collaborative community for research and innovation, not only for the University’s current diverse research initiatives, but also for collaborations with corporate entities and investigators from other regions and countries. In short, UM Innovation aspires to embrace and nurture the vibrant research initiatives of today’s University of Miami community and provides a foundation for the discoveries of tomorrow. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 17 On The Front Line Fueling the Research Powerhouse L ured by the prospect of conducting breakthrough translational research—the ability to translate research conducted in the laboratory into better and faster treatment options for patients—many new physician-scientists have joined the cancer center in recent months eager to complement UM/Sylvester’s investigative efforts in this area. Ronald Benveniste, M.D., Ph.D. Center in Houston, Benveniste rempressed by UM/Sylvester’s high ceived his B.S. in microbiology and clinical volume and potential for immunology from the University of strong clinical research, Ronald Miami and his M.D./Ph.D. degree Benveniste, M.D., Ph.D., recently from Washington University in St. joined UM/Sylvester’s ranks as Louis, Missouri. He completed his inclinical assistant professor of neu- ternship and neurosurgery residency rological surgery. In this position, at Mount Sinai School of Medicine Benveniste plans to develop a neu- in New York in 2006 and finished his rosurgical oncology practice (in fellowship in July 2007. close collaboration with the Miami VA Hospital) as well as introduce clinical research protocols for brain tumor patients at UM/Sylvester. “ The neurosurgical faculty is very skilled and respected, and I am excited about working with them and learning from them,” Jennifer Clarke, Ph.D. says Benveniste, a member Ronald Benveniste, M.D., Ph.D. of the Neurological Cancer Site Disease Group. Jennifer Clarke, Ph.D. One of Benveniste’s main research ennifer Clarke, Ph.D., joined goals is to establish a research program UM/Sylvester in September as an focused on determining how cancers assistant professor in the Department spread to the brain so that better of Epidemiology and Public Health protocols for detecting and preventing at the Miller School of Medicine. brain metastasis can be developed. His Clarke received her Ph.D. in statistics clinical interests include brain tumor from Pennsylvania State University surgery, particularly brain metastases, and completed a post-doctoral felgliomas (tumors that arise from the lowship at the National Institute support cells of the brain), and pitu- of Statistical Sciences in Research itary tumors. Triangle Park, North Carolina, before A past neurosurgical oncology joining Duke University as an assisfellow at the M.D. Anderson Cancer tant research professor in 2001. I J 10 18 Quest Clarke’s decision to come to Miami was based upon the abundance of top notch researchers in genetics/genomics, including those in the new Miami Institute for Human Genomics (MIHG) at the Miller School of Medicine. She is looking forward to working with her colleagues in MIHG and in cardiology and oncology who have recently moved to Miami from Duke University. “My primary research area is statistical methodology for high dimensional data of multiple types, specifically ‘omics’ data—genomics, metabolomics, and proteomics,” says Clarke. “I develop and apply these methodologies in several application areas including oncology and cardiology.” Clarke received undergraduate degrees from Skidmore College in Saratoga Springs, New York and holds a master’s degree from Carnegie Mellon University in Pittsburgh, Pennsylvania. Catherine Jones, M.D. atherine Jones, M.D., recently joined UM/Sylvester as a clinical instructor in the Department of Medicine, Division of HematologyOncology. She comes to the cancer center from Vanderbilt University in Nashville, Tennessee, where she recently completed a fellowship in C The Magazine of the University of Miami Sylvester Comprehensive Cancer Center general thoracic surgery component novel signaling pathways that lead to of the Division of Cardiothoracic cell transformation and tumorigenisis. Specifically, he and his team are Surgery. Nguyen received his medical de- investigating the signaling pathways gree from McGill University Medical involving a candidate tumor suppressor, Disabled-2 School in Montreal, (Dab2) and GATA Canada. He completed a two-year clinical transcription factors, and research fellowin the development ship in thoracic oncolof ovarian cancer. ogy at the University Additional interests of Texas, M.D. Anof the research team Dao Nguyen, M.D. derson Cancer Center include the biology ao Nguyen, M.D., joined UM/Syl- in Houston, Texas, of menopause and vester in September 2007, as an before being recruited embryonic stem cells associate professor of surgery and to the NCI. in early mammalian chief of the Thoracic Surgery Section, embryonic developCatherine Jones, M.D. ment. Division of Cardiothoracic Surgery in Xiangxi Xu, Ph.D. iangxi (Michael) Xu comes from the DeWitt Daughtry Family Department of Surgery at the Miller School Xu, Ph.D., joined the Fox Chase Cancer of Medicine. UM/Sylvester in OcCenter in Philadelphia, Pennsylvania. Nguyen was recruited to UM/Syl- tober as professor of vester from the National Cancer medicine and chief “I am very enthusiastic about the exciting Institute (NCI) of the National In- of ovarian cancer restitutes of Health, where he served search, where he will new environment, and as a principal investigator for more be charged with deI am highly optimistic than nine years. “I decided to come veloping an ovarian about the potential for to UM/Sylvester because of the cancer research prous to succeed and contribute to the research tremendous opportunity for transla- gram. Xu holds joint Dao Nguyen, M.D. tional research and clinical activity in appointments in the and academic achievement at the University general thoracic surgery, particularly Departments of Mediof Miami,” he says. thoracic oncology, my chosen field of cine and Obstetrics and Gynecology. His Xu received his expertise,” says Nguyen. undergraduate deThe focus of Nguyen’s research research interests lie gree from Zhongis to selectively stimulate the death- primarily in ovarian shan University in promoting signal transduction path- cancer. way in cancer cells while sparing Xu and his reGuangzhou, China, the normal cells using recombinant search team will transand his Ph.D. from protein or viral vectors. “I am also fer three NCI and Emory University in interested in using drugs to inhibit Department of DeAtlanta, Georgia. He growth-promoting signal transduc- fense funded research Xiangxi (Michael) Xu, Ph.D. completed postdoction pathways in cancer cells to projects to UM/Syltoral training at Coturn off their malignant behaviors,” vester. All of these projects are on lumbia University Medical Center says Nguyen. He plans to con- the study of ovarian cancer biology in New York and St. Jude Children’s tinue his research efforts at UM/Syl- and etiology, to better understand the Research Hospital in Memphis, vester with the goal to strengthen the molecular alterations of known and Tennessee. hematology-oncology. At UM/Sylvester, Jones will focus her efforts on gastrointestinal oncology where she will concentrate on some of her main research interests, including Phase I drug development and health disparities research. Jones holds an M.D. degree and a Master’s of Science in Clinical Investigation from Michigan State University in East Lansing, Michigan. D X Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 19 in the news Survey Reveals Disparities in Skin Cancer Knowledge Among High School Students esearchers from the University of Miami Sylvester Comprehensive Cancer Center surveyed students at a Miami-Dade County public high school and found white Hispanic teens were more likely to use tanning beds and less likely to consider themselves at risk for skin cancer or protect themselves from the sun than white non-Hispanic teens. Exposure to the sun’s ultraviolet (UV) rays is a major risk factor for melanoma and non-melanoma skin cancers, and the majority of lifetime exposure occurs by age 18, according to a study led by Robert S. Kirsner, M.D., Ph.D., professor and vice chair of the Department of Dermatology and Cu- R taneous Surgery and a member of the Melanoma and Related Skin Cancers Site Disease Group at UM/Sylvester. White Hispanics have a lower rate of skin cancer than white non-Hispanics, but are more likely to be diagnosed at a later stage. The findings were published in the August 2007 issue of Archives of Dermatology, one of the JAMA Archives of Dermatology journals. In 2006, Kirsner and his colleagues published another study that found melanoma is diagnosed later among blacks and Hispanics compared to white patients, which suggests a lack of awareness among minorities about their melanoma risk. When melanoma is caught at an early stage before it has spread, the five-year survival rate is 98 percent. If the cancer isn’t caught until it has metastasized, or spread far from UM/Sylvester Physician-Scientist Wins Prestigious Award to Support Research on Viruses and Cancer J uan Carlos Ramos, M.D., assistant professor of clinical medicine in the Divi- sion of Hematology-Oncology at the Miller School of Medicine, was one of only five researchers in the nation to receive a Damon Runyon Clinical Investigator Award. The prestigious award provides $450,000 in research funding and specifically recognizes promising “translational” research (translating research findings into new and better means of cancer prevention, diagnosis, and treatment) and investigator support over three years. The award will support his groundbreaking work on the role of an oncogenic protein in adult T-cell leukemia/lymphoma (ATLL). ATLL is caused by the human T-cell leukemia virus (HTLV-I) Juan Carlos and is endemic in southern Japan, in certain regions of Brazil, Ramos, M.D. as well as in western Africa. It is a relatively rare diagnosis in the United States, affecting fewer than 1,000 people. But because the disease also is prevalent in the Caribbean islands, which are largely populated by African descendants, like Haiti and Jamaica, South Florida has the highest incidence rate in the country. The disease carries a dismal prognosis. Ramos’ work promises to help predict which patients will respond to interferonbased therapy so that all ATLL patients receive the most effective treatment soon after diagnosis. 10 20 Quest where it began, survival dwindles to 16 percent. “Even after controlling for skin cancer risk factors, white Hispanic students had differences in knowledge and behavior related to skin cancer protection. This suggests delayed diagnosis and the rise of skin cancer in Hispanics may be due to lack of knowledge,” explains Kirsner. “This provides opportunities for intervention.” Pain Pioneer Joins School of Medicine elvin C. Gitlin, M.D., F.A.C.P.M., knows a lot about pain. In fact, he’s a noted pain expert. His pioneering work includes a virtual blueprint for treating chronic pain with opioids, guidelines he first drafted in 1997 for a World Congress of Neurologists symposium. After many years of work in medical institutions across the country—including more than a decade in New Orleans (where, after Hurricane Katrina, he used a cell phone to hold a hospital’s anesthesiology department together)—Gitlin has brought his intricate and specialized knowledge to the Miller School of Medicine. In his new role as professor and vice chair of the Department of Anesthesiology, Gitlin plans to maximize the potential of the department to provide optimal care to patients locally, regionally, and internationally. Gitlin also will be charged with enhancing the Department of Anesthesiology’s multidisciplinary pain management facility that provides state-of-the-art pain relief treatment and education to patients from around world. Researchers at the center also conduct cutting-edge research to discover new treatments for refractory pain conditions. M The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Pain management is essential for many cancer patients and is a key component of their treatment. As a result, Gitlin will work closely with patients and staff at UM/Sylvester, where physicians who are board-certified in pain management provide cutting-edge pain management services. From left to right: Stanley Thornton, board member, Miami-Dade/Monroe ACS; Dr. Joseph D. Rosenblatt; ACS Institutional Research Grant Award Ceremony icking off a formal award ceremony in August, UM/Sylvester’s Associate Director for Clinical and Translational Research, Joseph D. Rosenblatt, M.D., introduced the 2006 and 2007 UM/Sylvester recipients of the American Cancer Society’s (ASC) Institutional Research Grant Award. The 2007 grant recipients are Noella Dietz, Ph.D., Maria-Elena Jockovich, Ph.D., and Norito Takenaka, Ph.D. The 2006 awardees were Amjad Farooq, Ph.D., and Khaled Tolba, M.D. The grant provides funding for meritorious cancer research that cannot be readily supported through other funding mechanisms. The primary objective of the ACS grant is to provide seed money of up to $45,000 to young investigators who have no current national peer-reviewed grant support, thus encouraging junior investigators to participate in cancer research. Rosenblatt serves as the principal investigator of the ACS research grant. K Dr. Khaled Tolba; Lilliam S. Machado, board chair, Miami-Dade/Monroe ACS; and Berta Rios, Ph.D., other significant scientific activities, achievements, and honors. “Service on a study section also requires mature judgment and objectivity as well as the ability to work effectively in a group, qualities we believe Dr. Lokeshwar will bring to this important task,” stated Toni Scarpa, M.D., Ph.D., director, Center for Scientific Review, Department of Health and Human Services. area executive director, Miami-Dade/Monroe ACS urology and cell biology and anatomy at the Miller School of Medicine, recently was invited by the Department of Health and Human Services to serve as a member of the Development Therapeutics Study Section, Center for Scientific Review. Her new term of service began on July 1, 2007 and ends June 20, 2011. Members for this appointment are selected on the basis of their demonstrated competence and achievement in their scientific discipline as evidenced by the quality of research accomplishments, publications in scientific journals, and Wolfson Elected to Board of Nationally Recognized Gynecologic Oncology Group M/Sylvester radiation oncologist Aaron H. Wolfson, M.D., UM/ Jackson Cancer Committee Chair, and professor and vice chair of the Department of Radiation Oncology at the Miller School of Medicine, has been elected to serve on the board of directors of the Gynecologic Oncology Group (GOG). The GOG, which receives support from the National Institutes of Health, promotes excel- U Researchers Awarded a Leukemia and Lymphoma Society Award J oseph D. Rosenblatt, M.D., associate director of clinical and translational re- search at UM/Sylvester, and Seung-Uon Shin, M.D., research associate professor at the Miller School of Medicine, recently were awarded a three-year Leukemia and Lymphoma Society Award in the amount of $600,000. The goal of this Translational Research Award Program is to encourage and provide early-stage support for clinical research in leukemia, lymphoma, and myeloma, which is intended to develop Researcher Receives Prestigious Appointment inata B. Lokeshwar, Ph.D., a member of UM/Sylvester’s Molecular Targets and Developmental Therapeutics Program, and associate professor of V Quest innovative approaches to treatment, diagnosis, and prevention. Rosenblatt and Shin’s research will focus on the anti-CD20 antibody Rituximab, which is used to treat non-Hodgkin’s lymphomas. Rituximab activity depends, in part, upon its ability to activate immune cells called Natural Killer (NK) cells and cause them to attack lymphoma cells. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 21 in the news lence and quality in clinical and basic scientific research in the field of gynecologic cancer. Wolfson has worked in the field for many years to find treatments for cervical cancer and has a long history with the GOG. He has been attending GOG meetings since 1991, when he first arrived in Miami. Since 1992, Wolfson has served on the Radiation Oncology Committee. As part of that committee, he works to advance quality control and monitoring for women receiveing radiation. UM/Sylvester Researcher Finds Inhibitors that May Prove Beneficial in Breast Cancer Therapy ew research from UM/Sylvester suggests a role for the oncogene Src in ERα-negative breast cancers. N (An oncogene is a gene that controls cell growth.) ERα-negative cancers are more aggressive, have a worse prognosis than ERα-positive breast cancers, and have been thought to be estrogen dependent. Joyce M. Slingerland, M.D., Ph.D., F.R.C.P.(C), director of the Braman Family Breast Cancer Institute at UM/Sylvester, and colleagues studied 250 primary breast cancers and found that estrogen receptor alpha (ERα)-negative primary breast cancers and cell lines showed increased levels and/or activity of the protein Src, which cooperates with estrogen to activate ERα breakdown. Findings from the Slingerland lab provide hope for some women with ERα-negative breast cancers, who may benefit from the use of Src inhibitor drugs. The work was published in the FLORIDA CANCER CONFERENCE A mong the many UM/Sylvester faculty and staff at this year’s Florida Cancer Conference (formerly the Joint Cancer Conference) at the Breakers in Palm Beach were Ana R. Espinosa, R.N., B.S.N., O.C.N., manager, site disease group; Ricki D. Meadvin, R.N., O.C.N., manager, quality and standards and employee health; Joyce Rios, R.N., B.S.N., O.C.N., surgical oncology clinic nurse manager; and Jacqueline Cereijo, R.N., B.S.N., neuro-oncology nurse coordinator. The varied presentations given at the conference were designed for all health care providers involved with cancer care—from primary care physicians to general surgeons and medical oncologists, as well as oncology nurses and researchers, with a special focus on fellows. From left to right: Ana Espinosa, Ricki Meadvin, Joyce Rios, and Jacqueline Cereijo 10 22 Quest August 2007 issue of the Journal of Clinical Investigation. Slingerland’s research career has been devoted to the translation of mechanistic aspects of cell cycle and hormonal regulation of breast cancer. She has received numerous awards including the Doris Duke Distinguished Clinical Scientist Award. Her research has been funded by the National Cancer Institute, Department of Defense Breast Cancer Research Program, and the Breast Cancer Research Foundation. Braman Family Breast Cancer Institute at UM/Sylvester Announces grant Awardees he Office of Research Administration recently announced the Braman Family Breast Cancer Institute at UM/Sylvester 2007 developmental grants awardees. These one-year grants to qualified researchers provide $50,000 for operating expenses, equipment, and laboratory needs to support promising research in breast cancer. These developmental grants are intended to encourage and support promising new basic, translational, and clinical research in breast cancer. This year, a total of 14 investigators applied. The four awardees are: Gennaro D’Urso, Ph.D., from the Department of Molecular and Cellular Pharmacology; Mary Lou King, Ph.D., in the Department of Cell Biology and Anatomy; Jaime Merchán, M.D., a hematologist-oncologist in the Department of Medicine; and Keith Webster, Ph.D., from the Department of Molecular and Cellular Pharmacology. T The Magazine of the University of Miami Sylvester Comprehensive Cancer Center M AKING A D IFFERENCE Message from the board chair UM/Sylvester Board of Governors Fiscal Year 2007 (Through May 31, 2007) Joan Scheiner, Chair Joaquin F. Blaya, Chair Emeritus Rose Ellen Greene, Vice Chair Thomas B. Levinson, Vice Chair Jon Alexiou, Ph.D. Sheldon T. Anderson Cynthia L. Augustyn, J.D. Jose P. Bared Gloria Berkowitz Norman L. Braman Minette Brown Michele Chulick William Donelan Denny Feinsilver Michael B. Fernandez Thomas J. Fitzpatrick Bernard J. Fogel, M.D. David Fuente Gail Gidney Pascal J. Goldschmidt, M.D., F.A.C.C. W. Jarrard Goodwin, M.D., F.A.C.S. Mark Halpern Peggy Hollander Elsie Sterling Howard Donald E. Kubit, J.D. Alan S. Livingstone, M.D. Jayne S. Malfitano George Mencio, Jr., J.D. Joseph Natoli Steve Nuell, J.D. William O’Neill, M.D. Marvin O’ Quinn Dennis J. Patin, M.D. Nilda P. Peragallo, Dr.P.H., F.A.A.N. Barbara Pessel Joseph D. Rosenblatt, M.D. John Schulte H. Allan Shore, J.D. Anne C. Smith, R.N., M.B.A. David Stansberry Richard Spring Barbara Weintraub Joined the board since the beginning of fiscal year 2008 Michael Gittelman replaces David L. Stansberry, M.S. Jorge J. Guerra Jr., M.D. Marc E. Lippman, M.D. Aaron H. Wolfson, M.D., replaces Dennis J. Patin, M.D. Quest W hen I first walked through the doors of the University of Miami Sylvester Comprehensive Cancer Center ten years ago, I had been diagnosed with metastatic soft tissue sarcoma and was coming to meet my oncologist Pasquale Benedetto, M.D., for the first time. I knew at that moment that my future rested in the hands of the well-trained physicianscientists, nurses, and support staff that make up UM/Sylvester, and it was an awesome realization. My prognosis back then was not good. In fact, it was anticipated that I would live approximately 18 months. But with the care and guidance of my UM/Sylvester team, it has been an amazing ten years. Having experienced UM/Sylvester as a patient, I witnessed the cancer center from a completely different perspective. It was, and still is, a jewel of an institution— a complete healing facility. I also now know that small improvements made possible through research—such as changes that dramatically reduce the time it takes to perform a scanning procedure, for example—are tremendous strides for patients. We’re all focused on curing cancer, but when you’re a patient, every little step along the way is huge. Joan Scheiner After this life-changing experience, I have attempted to use my strength of spirit to accomplish good things. So it seemed only logical that I give back to the institution that made such a huge impact on my life and the lives of countless others. In 2001, I made a meaningful donation to UM/Sylvester and offered to help raise money to realize the endless possibilities that were out there for those faced with a cancer diagnosis. I became a member of the Founders Society, chair of UM/Sylvester’s Development Committee, co-chair of the cancer center’s five-year, $137 million capital campaign, and later a Grand Founder of UM/Sylvester. Today, as chair of the UM/Sylvester Board of Governors, I am working to develop an infrastructure that will ensure the success of future fundraising initiatives so that the funds raised continue to fuel the lifesaving research being conducted at UM/Sylvester. More importantly, I feel privileged to lead a board of committed, caring, and compassionate individuals all with the same mission in mind—to eradicate cancer, and while working to do so, improve the quality of life for all who deal with this dreaded disease. It is a goal that is achievable with your ongoing support. Joan Scheiner Chair, Board of Governors UM/Sylvester The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 23 M AKING A D IFFERENCE Cancer Survivors/Advocates Play the Role of Recruiters They’re not “head hunters” nor do they work for an executive search firm. But Jon and Shirley Alexiou, longtime patients and avid supporters of UM/Sylvester, skillfully recruited a physicianscientist to the cancer center when yet another cancer scare landed them at the National Cancer Institute (NCI) in Bethesda, Maryland in 2006. T hat’s where Shirley would undergo surgery for a melanoma metastasis that developed in one of her lungs—this almost four years after she had successfully beaten melanoma on her scalp. In 2001, the first time she was Jon and Shirley Alexiou diagnosed, Shirley underwent surgery and subsequent treatment, including at UM/Sylvester. She later participated immunotherapy—vaccines to stimulate in a NCI trial for an anti-melanoma the immune system to fight cancer— vaccine, which ended in 2003. Celebrations Luncheon is Reason to Celebrate A record number of more than 500 guests attended the Cancer community. Joyce M. Slingerland, M.D., Ph.D., F.R.C.P.(C), director Link luncheon and auction to raise awareness and funds of the Braman Family Breast Cancer Institute at UM/Sylvester, for breast cancer research. The Cancer Link Celebrations lun- spoke about the advances being made in breast cancer research cheon and fashion extravaganza, featuring the Mayda Cisneros at the Institute. Victoria Cummock made a surprise generous Couture Collection, was held on October 10 at Jungle Island. donation in honor of celebrant Althea Peck. Sponsors included Marlene Berg, luncheon chair, along with co-chairs Barbara BNY Mellon Wealth Management and the Armando Codina Berg, Ana Britti, Mayda Cisneros, Heather Davis, Liliana Dones, Family. Michael Alexander and his mother Carmen Alexander Cindy Eisaman, Cheryl Ettelman, Renee Gross, Susan Kaufman, Printup were crowned the King and Queen along with the court Bonnie Sepe, Harriet Shapiro, and current officers Micki Lewis, of celebrants Norma Jean Abraham, Bradford Tonic, Inc., Betty Wayne Haltiwanger, and Merri Grace McLeroy raised nearly Brandt, Dr. Barry Burak, Diane Madden, and Connie Russell. $117,000 for UM/Sylvester as they brought together the Miami Cancer Link is an organization dedicated to finding a cure for breast cancer by creating community awareness, educating the public, and holding special events that raise much-needed dollars for breast cancer research at UM/Sylvester. From left to right: Fashion designer Mayda Cisneros, Dr. Joyce Slingerland, Marlene Berg, and Micki Lewis, current Cancer Link president. Smaller photo, from left to right: Victoria Cummock and Althea Peck 10 24 Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Eerily reminiscent of her previous bout with cancer, Shirley and Jon packed their bags and headed back to the NCI in late 2006 to undergo surgery to remove a tiny lesion in her lung. Dao M. Nguyen, M.D., a tenure-track principal investigator in the Section of Thoracic Oncology of the Surgery Branch at the NCI, was assigned to her surgery. “He came into the exam room, and asked, ‘How do you like Miami?’” recalls Jon, himself a cancer survivor, who was diagnosed with squamous cell cancer at the base of the tongue in 1999. He was subsequently treated at UM/Sylvester and his cancer was eradicated. “Dr. Nguyen was very forthcoming, and said he was being recruited by UM/Sylvester as a thoracic surgeon,” adds Jon. He emailed UM/Sylvester Director W. Jarrard Goodwin, M.D., F.A.C.S., that same day. “Yes we are recruiting him. Bring that surgeon back with you,” Goodwin said. Meanwhile, the Alexious started talking to Nguyen about Miami. Goodwin is very pleased the recruitment effort was successful and that Jon and Shirley served as advocates for UM/Sylvester. “Jon and Shirley are two of our biggest supporters (both serve on the board of Friends for Sylvester, and recently became Grand Friends for Sylvester. Jon also sits on the Board of Governors). They’re so enthusiastic,” says Goodwin. “They essentially became recruiters for us.” Nguyen removed the nodule from Shirley’s lung through video-assisted thoracoscopy, a minimally invasive procedure that involves inserting an endoscope with a camera through a small incision. Shirley received three such incisions, an amazing feat compared to thoracotomy, which requires opening Quest the chest cavity with a large incision. The less invasive surgery allowed Shirley to be released within just two days. Nguyen informed the Alexious he’d be in Miami one week later for a second job interview at UM/Sylvester. The couple told him to give them a call once he was in town. When he arrived, the Alexious were waiting at Goodwin’s office. Nguyen recalls the encounter. “The Alexious are very nice people and extremely supportive of the cancer center,” says Nguyen, who joined UM/Sylvester in September. “They impacted my decision of moving to Miami.” (See page 19 for more information on Nguyen.) As for the Alexiou’s, they are thrilled this talented physician-scientist has joined UM/Sylvester’s ranks. “UM/Sylvester has been extraordinarily important in our lives,” say the Alexious, “so giving back to the cancer center is the least we can do.” Shop ‘Till you Drop with Key to the Cure he term “shopping” is music to the ears of many. And that’s exactly what took place at the kick-off party for the Saks Fifth Avenue-Bal Harbour Key to the Cure annual fundraiser and awareness campaign for women’s cancer research on October 18. “Saks Fifth Avenue-Bal Harbour is proud to support the University of Miami Sylvester Comphrensive Cancer Center through our annual charitable initiative, Key to the Cure. This incredible event is so much fun and has T Firm Finds Synergy When Partnering with UM/Sylvester W hen employees of Rachlin Cohen & Holtz LLP, a tax and business services agency that serves the tri-county area, met recently to decide which charitable organizations to support, they looked no further than their own backyard. Through its Rachlin Foundation, an employee contribution and corporate matching program that raises funds for charitable causes in the local community, the firm selected UM/Sylvester as one of the organizations to partner with due to its regional reach and its steadfast mission of finding a cure for cancer. UM/Sylvester is among four local charities chosen by the Rachlin Foundation to support in 2007. The foundation holds events throughout the year to raise money for numerous organizations, matching all contributions dollar for dollar. Last summer, the Rachlin Foundation announced its pledge of $18,500 to UM/Sylvester and presented its first installment of that pledge at a luncheon in Fort Lauderdale’s Riverside Hotel in August. From left to right: Suzie Ormento, executive director, Rachlin Foundation; Marilyn Emas, UM/Sylvester Executive Director of Development; and Lawrence H. Blum, managing partner for Rachlin Cohen The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 25 M AKING A D IFFERENCE gained the reputation as the kick-off party of the season. It’s a wonderful way to support such a great cause,” says Deborah Slack, general manager of Saks Fifth Avenue-Bal Harbour. “UM/Sylvester is such a leader. We value our partnership and the positive impact that we can have together in our community.” Together with the Entertainment Industry Foundation (EIF), Saks Fifth Avenue-Bal Harbour partnered with UM/Sylvester to host the Key to the Cure, a charity shopping weekend that took place October 18 through October 21. A percentage of the weekend’s sales benefited UM/Sylvester through EIF’s Women’s Cancer Research Fund. Nationwide, Saks stores and saks.com donated two percent of sales while Saks Fifth Av- From left to right: Alan Randolph, co-chair Saks Key to Cure; Deborah Slack, general manager of Saks Bal Harbour; UM/Sylvester’s Dr. Jerry Goodwin with Kim Wood and Jeff Peck, co chairs of Saks Key to the Cure “It’s not just about philanthropy… it’s personal” C ommunity leaders, Denny and Paul Feinsilver, along with their children Corey and Zack, shared their UM/Sylvester story and Sunday Supper in October with more than 100 friends. The Feinsilver Sunday Supper, an annual event, is the kick-off to the fundraising season and an event not to be missed. Former UM/Sylvester Board of Governor’s Chair Joaquin Blaya flew in from Frying Pan, Colorado to join the festivities. While Blaya may have traveled the longest distance, it was the Feinsilver’s and current Board chair, Joan Scheiner’s personal journeys from patients to survivors and now to cancer center advocates, that inspired new Friends for Sylvester, Founders, and Grand Founders to join them in their mission as builders of South Florida’s only university-based academic cancer center. Joining UM/Sylvester Director W. Jarrard Goodwin, M.D., F.A.C.S., and his wife Sharon, were Nancie Sturges, Lauren Sturges and fiancée Charles Fernandez, Nelly and Mike Farra, Terry O’Grady, and Shelly Woolf. Also in attendance were the 2008 In the Garden gala chair Lily Serviansky and her husband David, Barbara Havenick, Joni and Stanley Tate, Joy and Matt Zucker, Jennifer Stearns Buttrick, Florence Mufson, Helen and Sy Somerstein, and Suzie Ormento, representing the Rachlin Foundation. From left to right: Paul and Denny Feinsilver, Joaquin Blaya and daughter Monika, Sharon and Dr. Jerry Goodwin, and Joan and David Scheiner 10 26 Quest enue Outlet stores donated one percent of sales up to $1 million to local and national women’s cancer charities. More than 800 guests attended the event. Each guest paid $30, which went directly to UM/Sylvester to support cancer research. Partygoers enjoyed live music and food from A Joy Wallace Catering Production and Design Team, Social Miami at The Sagamore, China Grill, Tuscan Steak, Blue Door at the Delano, Mena Catering, La Marea at the Tides, Touch Catering, and Table 8, among others. Along with EIF, Ocean Drive and Grey Goose were Saks national charity partners for this event. “Our hope is that someday breast cancer will be treated more effectively so that every patient will be given increased quality of life,” says Irma Braman, honorary chair of the event. “That would be a real breakthrough and a source of great personal satisfaction for us.” This is the fifth year Braman has chaired Saks Fifth Avenue-Bal Harbor Key to the Cure. She was joined by co-chairs, Kim Wood, Jeff Peck, and Alan Randolph, who have co-chaired the event for two years. Special thanks also went to Mercedes Benz-USA for underwriting the event. The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Four Seasons Joins UM/Sylvester’s Lifesaving Mission ommitted to helping those who have been affected by cancer, the five-star Four Seasons Resort Palm Beach has partnered with UM/Sylvester. “As a company, Four Seasons is dedicated to finding a cure for cancer and raising awareness of this disease that touches all of our lives,” says Four Seasons Resort Manager Kathleen Horrigan. “Since 2005, Four Seasons has been pleased to partner with UM/Sylvester, one of the country’s leading cancer facilities, which shares our commitment in helping those who have been affected by this devastating disease.” In 2006, former Four Seasons Resort Palm Beach General Manager, Jamie Yarrow, kicked off a year of fundraising when he climbed Wyoming’s legendary Grand Teton in tribute to the Four Seasons employees who live and work with cancer every day. He also carried to the mountain’s summit the Flag of Hope—signed by Four C Seasons employees honoring the names of friends, co-workers, and loved ones affected by cancer. In addition to Yarrow’s climb, the hotel hosted a silent charity auction, a Thanksgiving Bake Sale, and a holiday breakfast with resort executives raising $27,000 for cancer research at UM/Sylvester. In 2007, the resort also hosted a celebrity bartender event at Amici in Palm Beach as part of their ongoing commitment to fund cancer research. “Spot Out Cancer” Event Gains Momentum early ten years ago Austin Gaines’ mother, Joan, was diagnosed with breast cancer. Instead of moping around, the life-altering event sprung the young Gaines into philanthropic action. Since that day, Gaines has proudly raised more than $200,000 for breast cancer research at UM/Sylvester. (Joan is a cancer survivor.) More recently, the young, tenacious, and charismatic philanthropist (at 22, Gaines is considered one of the N Friends For Sylvester Wall Dedication L youngest members of the Founders’ Society at UM/Sylvester) organized the seventh annual “Spot Out Cancer” fundraiser and silent auction in October, attracting more than 350 guests and raising nearly $40,000 in the process. By all accounts, the affair was a night to remember. Held at Saks Fifth Avenue-Dadeland and part of the national, week-long Saks Key to the Cure event, two percent of the sales from the weekend benefited breast cancer research at the Braman Family Breast Cancer Institute at UM/Sylvester. Event sponsors included Sandy Baker, Daryl Blinski M.D., Robert and Brenda Castellano, Christina Party Rentals, Eliza and Hugh Culverhouse, Harold Gaines, Joan and Louis Gaines, Tamara and Steve Gordon, Horne Plumbing, Magic City Poker Room at Flagler, Allen and Diane de Olazarra, R.E.T.C., Inc., R&S Windows, Schwarz- bach Family Foundation, Mark and Marie Siegel, and Sammi Siegel. Nineteen food and beverage sponsors also participated including Bacardi, Caramelo Restaurant, Fleming’s Prime Steakhouse, Jake’s Bar and Grill, and Whip n’ Dip, among others. ast September, members of the donor society Friends for Sylvester gathered in the foyer of UM/Sylvester for a wall dedication to welcome new Friends members. These individuals have either signed a ten-year, $10,000 pledge; have pledged $25,000 over ten years to become Grand Friends; or over time have donated between $10,000 and $25,000. Friends for Sylvester began in 1998 and since then has raised more than $3 million for cancer research. This year, the society, which has more than 300 members, added 46 new members to its roster. Pictured from left are: Rick Morgan, Friends for Sylvester board member; Dr. Jerry Goodwin, UM/Sylvester Director; Scott Notowitz, Grand Friend for Sylvester and board member; and Dr. Jorge Guerra, associate vice president for clinical affairs, From left to right: Austin Gaines, Joan Gaines, and Juan University of Miami Medical Group Lopez, general manager, Saks Fifth Avenue-Dadeland Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 27 M AKING A D IFFERENCE P a p J o u r n a l Papanicolaou Corps Celebrates 55th Anniversary with Generous Gift to UM/Sylvester I Ph.D., research assistant professor in the Department of Psychiatry and Behavioral Sciences; and Frank Penedo, Ph.D., associate professor of psychology. n celebration of its 55th anniversary in May, the cer Research announced a New Pap Corps Web Site is Launched generous gift of $3.15 million he Pap Corps recently Papanicolaou Corps for Can- T to fund cancer research at launched a new web site at www.papcorps.org. De- UM/Sylvester. The presentation, made at the annual signed to be informative and donor luncheon at the Wes- user friendly, the site includes tin Diplomat Resort and Spa general information on the in Hollywood, puts the Pap all-volunteer grassroots or- Corps closer to reaching its ganization, including all of the six-year, $14 million pledge From left to right: Pap Corps Treasurer Deborah Steiner, Pap Corps President vital programs it supports. The a year early. The Pap Corps, Barbara Pessel, UM/Sylvester Director Dr. Jerry Goodwin, UM/Sylvester web site is divided into nine founded in 1952, has more than Board of Governors Chair Joan Scheiner, and Dr. Pascal J. Goldschmidt, categories. Highlights from 17,000 members in Miami- senior vice president for medical affairs and dean of the Miller School the site include: Dade, Broward, and Palm of Medicine Home page—details the Pap Corps mission Beach counties who support cancer research at UM/Sylvester. statement and latest news. Our Members—lists the names of all Pap Corps units and includes a membership form for those interested in Pap Corps Announces Cancer Health Disparities Grant Awardees U Pap Dollars at Work—includes a pie chart outlining M/Sylvester and the Pap Corps recently announced how the 2007 UM/Sylvester gift of $3.15 million is being this year’s UM/Sylvester Pap Corps Cancer Health allocated. Disparities Grant Awardees. These Contributions/Opportunities—offers a description of one-year developmental grants, which all ongoing Pap Corps’ fundraising are funded by the Pap Corps’ $3.15 mil- opportunities. lion gift, provide $50,000 for operating expenses, equipment, and laboratory Breaking News—provides frequent updates on important in- needs to support promising research formation and breakthroughs from in studies targeting cancer health UM/Sylvester. disparities. The three awardees for From the Beginning— 2007 are Erin Kobetz, Ph.D., M.P.H., provides background and a brief his- assistant professor in the Department tory of the evolution of the Pap Corps. of Epidemiology and Public Health 10 28 joining the organization. To learn more about the Pap Corps and research scientist at the Bra- and to become acquainted with its man Family Breast Cancer Institute newly redesigned web site, go to at UM/Sylvester; Suzanne Lechner, www.papcorps.org. Quest The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Supp o r t R e a c h e s Ne w He i g h t s P reflect commitments achieve its lifesaving mission by reducing the burden of cancer for patients and their that were received families in South Florida. by May 31, 2007. Millennium Society The Harcourt M. and Virginia W. Sylvester Foundation, Inc. corporations, and foundations make to positively impact the lives of others. In the case of the hundreds of names listed below, they are helping UM/Sylvester Donors listed here UM/Sylvester Giving Societies hilanthropy doesn’t just happen. It’s a commitment that generous individuals, Women’s Cancer League and Partners Gail and Jeff Gidney Joan and J. David Scheiner Dr. Sonja Eiteljorg Sharon and Dr. W. Jarrard Goodwin Estate of Bernice Schneider David Etter and Steven Etter Ibis Society Muriel and Sherman Simon Nelly and Miguel Farra Florence Mufson Robert and Gertrude Barnett Family Foundation Rose Ellen and Gerald Greene Jill and Allen Greenwald Emanuelle and Allan Slaight Ferne and Jonathan Fels Teresa and Carlos Musibay Cancer Link Francine and Mel Harris Don Soffer The Rose and Irving Fien Philanthropic Fund Sandy and Stephen Muss Cynthia Davis Carr Carol Hesser Peggy Hollander Estate of Sherlock Hibbs Miami Society Joan Levy Cancer Foundation Lois and Sandy Hildebrandt Estate of Eugenia Dodson R. Kirk Landon Huizenga Family Foundation, Inc. Papanicolaou Corps for Cancer Research, Inc. Ryder System, Inc. Gloria and Bob Kolikof Jeanne and Richard Spring Gables Society United States Surgical Corporation Robert M. Kramer Trustee/ Richard H. Simons Charitable Trust Irma and Norman Braman Estate of Rose Zimmerman George E. Merrick Society B. and Donald Carlin* Estate of Dolores Chambreau Estate of Will Hudson Jan and Dan Lewis Peacock Foundation, Inc. Estelle and George Rosenfield Judy H. and John K. Schulte Woldenberg Foundation Woman’s Cancer Association of the University of Miami Susen and Herbert Grossman Health Foundation of South Florida Knight-Ridder, Inc. Estate of Audrey Renault H. Allan Shore * Donated $2.5 Million Nancy and Robert Frehling Niety and Gary Gerson Renee Varas Raquel and Jaime Gilinski Barbara and Michael Weintraub Jessica and Dean Goldfine Margaret and Melvin Good Renee and Jay Weiss Gloria and Jesse Gottlieb Family Foundation Weiss Family Foundation New Blank Family Foundation Carol and Al Novak The Nuell Family Ocean Bank Office Depot The Orchid Ball Committee, Inc. Sandra and Thomas Levinson Clara and Harvey Young Shirley H. and Benjamin Z. Gould Family Foundation Jan Lewis Founders Louis Grossman Honey and Al Pallot Blossom Leibowitz Susan and John Adams Wendy and Steven Gurowitz Potamkin Family Foundation In memory of G. Calvin Harris OSF America, Inc. Sheila and Michael Ashkin Lourdes and Joe Arriola AVINA Foundation Macy’s Fund of the Federated Foundation Cara and Bobby Balogh Estate of Rolande Meyers Susan and Leonard Miller The Bauer Bisgeier Foundation, Inc. Gordon R. Miller In memory of Anne Bennett Stuart Miller Marilyn and Fred Berens Isabel and Joaquin Blaya Barbara Nelson Bemnet Berhane Doree and Sy Bloom In memory of Edith K. Newman Marsha and Brian Bilzin Blank Family Foundation Northern Trust Tati and Ezra Katz Emeline and Wayne Boich Terrence M. O’Grady Deborah and Bruce Kaye Eileen and Robert Breier Frieda and Yair Oren Barry Kieselstein-Cord Susan and Arthur Brown Kit and William G. Pannill Diane and James Klotz Carls Furniture Inc. Irene and Bill Panoff/Porthole Cruise Magazine Amy Dean and Alan Kluger Katika and Jack Carmel Eileen and Donald Kramer Trudy and Paul Cejas Daughters of Penelope Dorothy and Aaron Podhurst Family Foundation Chasen Family Fund Estate of Florence and Gilbert Kulick In memory of Edward J. Schack and Elsa Herrera Denny and Paul Feinsilver Steven Posner Barbara and John Cirino Carole and William Landa Scharlin Family Foundation Linda and Terry Fenner Maria and Jose Recio James J. Colt Foundation Jonathan Laskin Fund Suzanne and Bert Schild Constance and Miguel B. Fernandez Harry M. Ringel Memorial Fund Wileen Coyne Lautenberg Foundation Lily and David Serviansky William L. Culbert, Jr. Ruth Levkoff Paula and Joel Friedland Dorothy and George Barrie Arvi and Leo Berger Dorothy and Jules Besserman Jane and Saul Bialilew Adam E. Carlin Roberta and Harvey Chaplin Chaplin Family Foundation Colson Hicks Eidson, P.A. Arlyn and Stephen Cypen Steven Dwoskin-Dwoskin Family Foundation Jane Mary Trau Neiman MarcusBal Harbour Peggy and Joe Armaly Fredi and Robert Consolo Bowman Foster Ashe Society Jennifer Spring Jeanette and Ted Fine Suzie and Scott Lustgarden Miriam and Jose Bared Sheila and David Fuente Daniel H. Spring Marion and Peter Mosheim J. Quin Machamer Grand Founders The Applebaum Foundation, Inc. Quest Marty and Barbara Zweig Foundation Jill and Adam Spring Jimmie and Eugene Montoya Lea and Sam Barr Barbara and Fred Havenick JoAnn and Mark Hildebrandt Lillian Hollywood Elsie and Eugene Howard Roslyn and Elmer Hurwitz Jefferson Lee Memorial Foundation Kate Obstgarten Private Foundation Benton and Ronnie Pumpian Qualified Leverage Providers In memory of Samuel J. Rabin Marilyn and Neil Ramo Linda Richman Jo-Anne Rifkind Susan and Mark Rodack Dorothy Levinson Rubin Consuelo and P. Nelson Rodriguez Zoveyda Rodriguez Fund for Lymphoma Research Carole and Robert Saland Joan and Jerry Robins Hazel and Irving Cypen Y. S. Liedman Families Barbara and Michael Sherman Doree and Malcolm Fromberg Eva and Leon Rubach Zita and Stuart Danoff Rita Lipton Roni and Harry Shier Barbara and Herbert Saks The Dayton Foundation Saks Fifth Avenue-Bal Harbour Jodi and Bob Dickinson Jayne and Christopher Malfitano Susan and Peter Sibley Austin Gaines-Joan G. Gaines Breast Cancer Fund Carol and Eli Ehrlich Rosalie Sidle Nancy and Al Malnik Amy and Todd Martin Italicized names—deceased The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 29 M AKING A D IFFERENCE Sheila and Robert Slewett Gonzalo Parodi Beatrice and Carlos Burns Slotnick Foundation Ruth Pfeffer Joan and Edward Butera Edward W. Smith Jr. Foundation Premier Parking Management Dana and Paul Caan Mercy and Robert Glowacki Alice and Alan Lash Phyllis Glukstad Terri and Dr. Stephen Lazarus Goldman and Haber Families/Officers of Dollar Star and Warehouse 99 Ruth Snyder Lillian Rosen Leandra and Richard Candia Jean and William Soman Estate of Seymour Rosenberg Anthony Carrillo, in memory of Sue B. Carrillo Lily and Dr. Joseph Rosenblatt The Casamayor Family of Cosmyk Images, Inc. Dorothy and Sam Rubin Peter Cassileth and R. Judith Ratzan Steven Gordon Helen and Sy Somerstein In loving memory of Dr. Stanley Sutnick Susan and David Strauss Sandra and Marvin Rubin Vanneck Bailey Foundation Dana Robin Goldman Reuben and Mollie Gordon Foundation Carol and Arthur Green Stuart Cauff Green Family Foundation Stephanie and David Schwartz Claire and Dr. Cesar Ceballos Elsa Greenberg Ellen and Jon Channing Lynn Griffin Arlene and Wayne Chaplin Dr. William Whelan Ellen and Stephen Shapiro, Marc, Stephanie, Brian and Ann Daniels Wien Family Foundation Joni and Bob Sheetz Williams Island, The Florida Riviera Robert Shenkman Norma and Allan Wilson Donna and C. Thomas Tew Harold Commings/In memory of Alice Commings Bruce Weber Philip Robert Consolo III Katherine Wachtel Zander Paul Zarcadoolas Joy and Matt Zucker The Rydz Family Dr. Diane Walder Ruth G. Wagner Waltman and Cohen Barton G. Weiss Janie and James D. Tate Estate of Richard Wolsten Jerome A. Yavitz Jerome A. Yavitz Charitable Foundation Eileen and Philip Youtie Janet and Richard Yulman Friends for Sylvester Iris and Martin Zeitler The Zubizarreta Family Carl Zwerner * One Founder wishes to remain anonymous. Grand Friends for Sylvester Shirley and Jon Alexiou Julia Anderson Lilia and Jose M. Fernandez Five Millers Family Foundation Muriel S. Freund Mildred and Irving Goldberg Gene Gomberg – The Continental Group, Ltd. Mary Graham Dorothea and Steven Green Robert Guterman Himmel Foundation Lawrence Hoff Barbara Lefcourt Laurence W. Levine Foundation, Inc. Jordan A. Linn Denise and Ruben Lujo Bernadette and Richard Marks John Mcguire Rita and Gilbert Michel, Jr. Shari and Scott Notowitz 10 30 Stefanie and Evan Reed Deborah and Robert Cohen Amy Reiter Susan Gutman Sheldon Lowe Mark and Honey Revitz Susan Hally and Michael Comras Ruth and Joseph Lucci Ann and Bruce Rhodes Reva and Michael Hanzman Mary Ellen Lynch and Leo I. George Valerie and Charles Riback Shirley and Bo Crane J. Ira and Nicki Harris Foundation Mackey Health Institute, Inc. Myrna and Norman Ricken Michele and Michael Criden Susan and Paul Herman Michelle and Glenn Cutler Thomas F. Hewitt Diane and Arthur Cohen Alicia M. Dahling Mary and Dwight Hill William E. Davis Barbara and Walter Hinterkopf Karyn and Dean Dekker Ruth Diamond Gina and Howard Berlin Mirta and Ramiro Betancourt Karen and Thomas Bezold Nancy and Jerry Blair Wayne Blikre Elaine and Rick Donoff Estate of Louis Ducoff Adele and Leonard Dublin Cassandra and William George Earle Marilyn and Kevin Emas Freda Epstien Beth and David Ertel Mary Claire and Alex Espenkotter FDP Corp. Colleen and Richard Fain Judy and Victor Farkas Elena and Oscar Feldenkreis Janet and James Field Barbara and Paul Finizio Todd Eric Fleischman William Fox Jr. Foundation Elisabeth and Stephen Frank Jackie and Burt Bloom Nirit and Warren Freistat Michael and Corina Browanik Eugene Friedlander Jill and Harold Gaffin Barbara and Irving Brown Barbara and Richard Garrett Jacquelyn and Bruce Brown Jeffrey Brown Jodi and Scott Brown Alden and Robert Burlington Quest Marilyn and Herbert Potash Joyce and Albie Lichtman Florence and Sheldon Anderson Yolanda Cecilia and Jeffrey Berkowitz Suzanne and Mark Levitats Sheldon Guren Leslie and Peter Diamond Robert R. Bellamy Memorial Foundation George, Beverly, Glenn and Tracy Porter Lisa and Stephen Levine Arthur N. Queler Bonnie and Jonathan Aibel Pat and Gary Becker Mary and Lester Pokorne Kathy and Allen Levi Marilyn and Richard Lewis Marianne and John Devine Jose A. Bechara Podhurst Orseck, P.A. Kathy and Richard Lesser Martin Guiry Ernesto J. D’Escoubet II Susan and Joel Barnett Myrna Picken City First Mortgage Corp./ Fiske Family Sari and Arthur Agatston Antoinette and Gail Byron Baldwin Deborah and Daniel Finkle Lehman Dealership Enterprises, Inc. Lisa and Michael Puder Betty and John Abstein Lisa and Anthony Askowitz Erin and Richard Pfenniger Andrea and David Grossman John Deo, M.D. Bonnie and Gerald Askowitz Terry Cardwell Jean and Joel Perwin Sidney Lefcourt Sylvia and Robert Powell Homero de la Torre Bowen A. Arnold Carol and Mark Brooks Michael Pernick Bruce Levy, The Emerald Companies Diane and Michael Abrams Randi and Michael Applebaum Geraldine and Donald Bohning Rita and Hal Leeds Wayne M. Pathman – Phillips, Eisinger, Pathman Carol and Meron Levitats Federico Abascal Gail and Stewart Appelrouth JoAnn and Roni Laskin Ilene and Henry Gayer The Marilyn Gaylord Charitable Foundation Mathilda Glasser Glassman Development Hite Foundation Jacqueline and Lawrence Hoff Rita and Benjamin Holloway Fana and Abel Holtz Toni and Daniel M. Holtz William E. Hutton III Barbara and Jerry Isan Judith and Richard Jacobs Pam and Gil Jacobson Bernard Janis Ruth and Bernard Madoff Penny and H. Larry Mager Jeff Mandell Leana and Steven Marks Alexandra Mastriana-Solal and F. Ronald Mastriana Linda and Charles McIntyre Theresa A. Meerbott Janet Risi Teddi and Harvey Robbins Ophelia and Juan Roca Nancy and Ted Rogenski Victoria J. Rogers/In memory of Alvin E. Rogers Becky and David Rosenbaum Arlene and Laurans Mendelson Donna C. Ross Lisa and Victor Mendelson Dora and Steven Rubin Jane and Robert Meyerhoff Richard P. Millard, President and CEO, Tecton Hospitality Alison Miller and Joseph Bolton Edgar Miller Andrew D. Jubelt/ In recognition of my father, Paul Jubelt Mary and Mark Mills Ana and Manuel Kadre Amy and Ricky Mittelberg Lori and Marc Kahn Martin Kalb Renu Mody and Kevin Fitzmaurice Jennifer and Scott Kaplan Tracy and David Moret Jodie and Sy Kaplan Patti and Rick Morgan Missy Kardonski Denise and James Morris Arden and Jack Karson Melvin Morse Jane and Gerald Katcher Yiska and Peter Moser Steven and Hillary Kates Kristen and Wirth Munroe Kathy Kaufler Deirdre and Craig Nash Lois and Eugene Kessler Nemiroff and Auslander, P.A. Linda and Kenneth Keyes Gina and Jonathan New Leah Kleman Monica and Robert New The Konrad Family/ In memory of Stephan Foreman Debbie and Jim Nolan Kotel Foundation Sherry and Rudy Kranys Alexandra and Rafael Ordonez David Kraslow Mirtha Orue Muller Betsy Ann Lambert-King Fund/Justin Jones Joe Pallant Susan and Richard Lampen Alan Richardson Lynn and Fernando Miranda Larry Orbach and Philip Epstein Suzanne Pallot and Larry Major Tobi and Mark Rousso Stephanie and David Schwartz Jeff Safchik Douglas J. Sanders Sylvia and Rowland Schaefer Sonya Schattman Monica and Rick Schatz Daniel Shapiro Scheck Family Foundation Audrey Schneiderman/In honor of Mr. and Mrs. Maynard Goldberg Marcia and Larry Schuffman Ida and Robert Schwartz/In memory of Sarita Kaufman Gail and Joseph Serota Cotten Shephard Ellen and Craig Sherman Dorothy F. Sibley Lois H. Siegel Susan and Scott Silver Marlene K. Silverman – Greenberg Traurig Barbara Silverman Steve Silverman Jacqueline and Sydney I. Silverman Alan M. Slewett Patricia and Alan Sokol The Magazine of the University of Miami Sylvester Comprehensive Cancer Center LaReine Fedor Sparrer In memory of Vera Goldfenkoff, love Rachel Golden Koff, love Rachel United Automobile Insurance Company Kim and Tom Wood Peter Andolina Ray Ellen and Allan Yarkin Charmettes, Inc. Dade Country Chapter Fitness For Women Management Carmen and Manuel Villamanan Jane Yudell Anna Miller Circle of Homestead Murray Chermak Fleming and Fleming, PLLC Eric Zeitlin Art of Possibilities Donna Chiozzi Susan and Richard Zinn Arthur J. Gallagher Foundation Camille Cilli Florida International Bankers Association Asthma and Allergy Associates of Florida Coconut Grove Bank David Sporn – Coldwell Banker Real Estate Alexandra Villoch Claudia and Jeffrey Springer Cheryl S. Waters Linda and David Stansberry Jeanette Wax, in honor of my family Stearns, Weaver, Miller, Weissler, Alhadeff, and Sitterson, P.A. Dr. Susan and Rocky Stein Lucienne and Bill Steinberg Felicia and Blair Walker Sharon and Marc Watson Helene and Stephen Weicholz Randi and Daniel Weinbach Robert Zuckerman * Five Friends for Sylvester members wish to remain anonymous. Avon US Beauty Bank of America Young Philanthopists for Sylvester Bank United Louise and Daniel Barclay Deborah and Scott Barkow Christine and Michael Weinberg Lorel Bacon Monika Blaya Barnard Construction Co. Inc Patti and Alan Weinstein Amy and Rob Boyers Isaac Bassan Rochelle and Steven Weinstein Loana Cervantes Anne M. and James A. Stevenson Judy and Sherwood Weiser Corey Feinsilver Carolyn and Bernard Baumel Zack Feinsilver Barbara Bear Marijo and James Stewart Lynda and Douglas Weiser Katie and Michael Gilden Julie and William Beckham Barbara and Barry Sugerman Warren Weiser Amanda Goodwin Jeffrey Bercow Barbara and Pedro Bermann Jack Taffer Shelley and Eric Weiss Ann Kaufman Gomez and Dr. Jorge Gomez Dr. Erin Kobetz and Dr. Joshua Diem Bienenfeld, Lasek and Starr, LLC Matt and Orietta Levinson Ursula Billie Jennifer and Steve Medwin Gabriel Birger Lizzi Nuell and Ryan Rosalsky Helen Blauvelt Jennifer Olmedo-Rodriguez and Alex R. Rodriquez Diane and Robert Bok Sterling Financial Corporation Hana and Tibor Stern Victor Stern Dr. Sally and R. Joel Weiss Betty and Maury Terkel Robin and Roger Terrone Nina Williams Linda and Denis Trupkin Dorothy and Melvin Wolff/ In memory of Dr. Theodore M. Wolff Alina and Harry N. Turk Elinor B. Wolff Christiane and Christopher Tyson Wollowick Family Foundation Paula and Peter Trematerra Dekla and Matty Oren Melissa and Gil Oren DONOR RECOGNITION SOCIETIES (cumulative giving levels) M i ll e n i u m S o c i e t y $50 million and above M IA M I S o c i e t y $10 million and above Gables Society $5 million and above G e o r g e E . M ERRICK S o c i e t y $1 million and above B o wm a n F o s t e r ASHE S o c i e t y $500,000-$999,999 IBIS S o c i e t y $250,000-$499,999 Morgan Ostrow Tiffany Scaparotti Diana and Patrick Schmedeman Samantha and Mason Sharpe Monica and Nelson Taracido Donors who gave $250 or more Gifts received during fiscal year June 1, 2006 - May 31, 2007 of $250 or more, alphabetically listed. Acolite and Claude United Sign Company Inc. Jayusia and Alan Bernstein Jill and David Bockorny Muki Bolton Bombardier Ronald Book Braka Philanthropic Foundation Betty Brandt Natalie and Charles Brecker Tamara and Cesar Clavero Patricia and Dan Cohen Rita and Joel Cohen Esther and Owen Colliflower Community Redevelopment Agency of Delray Beach Conese Foundation, Inc. Frank Garcia Nancy Copperthwaite Evelyn Gargano Coral Gables Bail Bonds Garner Foundation, Inc. Robert Corirossi Millicent and Herbert Geist Corpus Christi Greyhound Racing Association Lynn and James Gelsomin Cindy Cossin Melissa and Thomas Genesio Susan and Joseph Coulter James Gillis Creative Marketing Partners Ginger Spirits Marketing Geraldine Dana Nancy and Daniel Ginsberg Edwidge Danticat Dauer Family Foundation, Inc. Denise and Marshall Glasser David Kosh and Ruth Kosh Foundation Gilbert Glen Bernard Goldstein Dears Foundation, Inc. Frank Gomez Delaware North Companies Virgina and Richard M. Gonzalez Diane Delella Leslie Delman Aileen and Stuart Disick Kathleen Downey Marilyn Drescher Dunwody, White, and Landon, P.A. John Caldwell Jose Calvo Rhona Fromberg Ina and Elliot Gant Brad Buchanan Calder Race Course Carol and Mark Fried Jerome Cooper Susan and Sidney Dulman CAH Palm Beach Friebert, Finerty and St. John S.C. Dora Gallart Melissa DuBose Digno Caballero Simon Freakley Michelle and Thomas Conroy Brown Charity Foundation, Inc. C and F Electric, Inc. Juan Fra Paula Fruchtman Edith Duarte Viera Florencio Busot Shari and Glenn Fox Stuart Connor Joyce and Bruce Brodbeck Lori Buchbinder Dolores and Lloyd Foley Joe Edell Michael Edelman Andrea and Aaron Edelstein Caryl and Murray Eisen Hala and Sami ElhabashiMnaymneh Benjamin Essien Grad Foundation Patricia and William Graham Sue and Alan Graubert Anne Green Greenburg-May Foundation Greenway Women’s Golf Association Ted Grossman Brenda and Donald Hagan Diane and Ernest Halpryn Robert Harrison Linda Hartnett Amy and Bruce Hausman William Hayes Marcia and Richard Hendler GRAN D FOUN D ERS $100,000-$249,999 Wilda and Alfonso Adderly Matthew Calvo Leon Alexander Camner Family Foundation Ethel and W. George Kennedy Family Foundation, Inc. FOUN D ERS $50,000-$99,999 Patty Allen Camp Lenny Foundation Inc. Excelsior Designs Inc. Robert Hertzberg Ruth and Myron Altschuler Capital Rental Agency Inc. Fima Falic Jill Hertzberg GRAN D FRIEN D s f o r S y l v e s t e r $25,000-$49,999 Lisette Alvarez Carmen and Gerardo Capo Mary Beth and Dan Fasano Joseph Himmelstein Am Tote Gisela and Richard Cardonne Ely Thomas Fedoration Paul Himmerlrich Vicki and David Carver Carla Feilbach Helene and Philip Hixon Beatrice and Harry Feldman Hobbs Foundation Corp. Maximilian Feldstein Marcia Hochberg Darleen Fenster Jeffrey Horowitz Joseph Feshbach Steven Horton FRIEN D S FOR SY L VESTER $10,000-$24,999 Young Philanthropists FOR SY L VESTER $2,000 Isabelle Amdur American Airlines American Gem Associates, Inc. American Italian Association Issolthe Andino Quest Thomas Cash Merryl and Kenneth Chaitman Brenda and Benton Chambliss Patricia Allan Herbert Nyria and Manuel Herran Michael Fischer Italicized names—deceased The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 31 M AKING A D IFFERENCE Bob Hover Paula Levine Lynne and Gary Penrith Michael Silva West 84 Corp. Enid and David Howell David Levine Raquel Silverstein William Wickman JMH Financial Corporation Peggy Hudson Robert Levine Perlman Family Supporting Fdn. George Wilson Kamp Partners Levine, Busch, Schnepper and Stein Janet and Stanley Perlmeter Kathleen and Robert Slater Angie Hughes Stacie and David Smith Sidney Workman Kaye & Associates P.A. Peggy and Stanley Smith Maria Jose and Fredrick Wright Kiene, Hand & Company, P.A. Lillian and Louis Yagoda Kluger, Peretz, Kaplan & Berlin P.l. H. Scott Huizenga Marilyn and Garry Hurewitz Andrea and William Hutchinson Juliano Ibarra Images by Jda John Irwin Isle of Capri Casinos, Inc. Marian and Robert Israel Iza and Sons, Inc. Robert Jablow Sondra and David Jackowitz Myrtle and James Jackson Saul Levy Barbara and David Lipman Littman Family Foundation, Inc Virginia and Edwin Lively Lois B. Victor Foundation Francine and Norry Luria Bernard Madoff Maier Foundation, Inc. Raymond Marks J. Peter Martin Michael Maura Jacksonville Greyhound Racing, Inc. Doris and Allan McLeod Gilbert and Joan Jacobs Peter Meckler Lambert Jacobs Joseph Merback Robert Jaffe Meridian International Group Jampro Demolition, Inc. Anthony Japour Elsa Johnson Everett Jones Christine and John Jordan Carrie McQuire Otto David Merson Metro Bank George Meyer Marian and Marc Milgram Tasha Joseph Joseph and Sherrie Garfield Charitable Foundation, Inc. Susan Miller Caryl and Abram Kaplan Jane Kass Katcher Family Foundation, Inc. Peggy Katz Shulamit and Chaim Katzman Kaufman Foundation,Inc. King’s Knights Lodge Knights of Pythias Eric Kline Patrick Pfeffer Nikos Pharasles Phoenix Realty Advisors, Inc. Pioneer Shipping Inc. Phyllis and Stephen Platt Aida and Victor Politano Bruce Polozker Kirk Pond Lezlie Poyastro Protravel International Inc. Lawrence Puckett Guillermo Puente-Duany Pyska, Blackmon, Ley, Mowers and Kelley Mary and William Quesenberry Deborah and Paul Ragsdale Xiomara Ramos Macky and Jerry Milgram Joan Kaminski Ronnie Pertnoy Gail and Robert Milhous Jo Ann Rauch Red Sail, LTD. Inc. Lillian Redlich Sylvie and Michael Reed Susan and Dennis Richard David Miller Roberts Communications Network Milne, LTD. Lawrence and Patricia Paretta Foundation Isabel and Marvin Leibowitz Diane and Jean Lejeune Sandra and Stanton Levin Sidney Levin 10 32 Linda and Peter Steckley Norman Stein Priscilla Stein Helen and Martin Stein Step Steam It Corp. Stuzin Family Partnership LLTD Pitzel Foundation Joanne Summer Eileen and Paul Swaye Susan and Mark Rubin Nebarda Enterprises, Inc. Leslie and Steve Saiontz Judith and Robert Newman Carrie and David Schulman Robin and Carlos Palomares Lorraine and Robert Schustak Patricia Papper Parent Services, Inc. Bernice and Harry Schwenke Keith Parker Tracy and Paul Shelowitz Katherine and Joel Parks Shoffner Consulting Corp. Robert Parks Rosalie Sidle Parsons Lois Siegel Linda Pelletier Rose Sierra Quest We would like to take this opportunity to thank our corporate partners whose support is deeply appreciated. We look forward to our continued partnership. Mark E. Fried Professional Association Luminaire Inc. Macy’s Florida Stores Miami Overseas Chinese Assoc. Inc. Miami Parking Authority Park West Parking Mary Nash Palm Beach Kennel Club. Lexus of Kendall BJA Real Estate Holdings Inc. Nancy and Robert Sturges Tom Thumb Food Stores Inc. Susan Owen Corporate Partners Palm Bay Imports, Inc. Elaine A. Stuebner Myron Roth Isabelle and Charles Schuette Lewis B. Freeman & Partners, Inc. Stuart Newman Associates Elizabeth and Arthur Murphy Willa and Martin Oren Levinson’s Jewelers Oceania Cruises Joseph Muraskin James Schoonmaker Candy and Steve Zuckerman Bet Miami Greyhound Partnership Sondra Title Sue Ellen and Robert Schneider Jackie Zucker Lehman Dealership Enterprises American Wholesalers, Inc. Donna Tillery Orange Bowl Foundation, Inc. Amy Zakarin Law Offices of Brandon A. Rotbart Blair and John Strickroot Roy Rotella David Schaecter Burton Young Morrison, Brown, Argiz & Farra Alan Rosenthal Kim and Martin Rubin Shannon and James Yarrow Akerman Senterfitt Steubenville Kennell W Virging Corporation Patricia Moss Audrey Schanfald Nidia and Enrique Lavernia Diana and Eugene Stearns Miriam Morejon Elizabeth and Francisco Olazabal Lauren Foundation State Services Systems, Inc. Robert Thomas Pauline and James O’Donnell Lynda and Steven Latner Stamps Family Charitable Foundation, Inc. Beard Rosenblatt Jacqueline and Irwin Kott Agnes and Richard Larimore St. Hugh School Moody Electric, Inc. Marlim and David Sandri Chyna LaMonte Larry Spring Karen Tharp Susana Sanchez-Armengol Judith and Barry Kutun Ellen Spitzer Cathy Rooney Peter O’Brien Sarah Kupchik South Miami Corporation Moody Bible Institute Lisa and Geoffrey Newman Anna and Lester Kreider Richard Sorgini Cynthia Swol Barbara and Joel Kopelman Jena Krieger Carol and Richard Songer Martha and Francisco Robles Isaac Moinester Samuel E. and Mary W. Thatcher Foundation Inc. Ted Konover Sokaogon Chippewa Community Foundation, Inc. Lucille Talianoff Thomas Torbert Total Managed Care Services, Inc. Thomas G. Travis Triangle Community Foundation Bloomingdale’s Inc. Bluestein, Wayne & Weintraub, P.A. Boca Raton Community Hospital Foundation, Inc. Buchanan Ingersoll & Ronney Business Centers International CareerXchange Caribbean Resources Inc. Carls Furniture, Inc. Chase Music & Entertainment City National Bank of Florida Commercial Bank of Kendall Pamsco, Inc. Pharmed Group Corp. Physicians Health Center Premier Parking Management Rafferty Capital Markets Regent South Beach S. Danoff USA Ltd. Sabia Communications, Inc. Saks Fifth Avenue/ Bal Harbour Salomon Construction & Roofing Corp. Shook, Hardy & Bacon L.L.P. Smith Barney Somerstein Land South Beach Insurance Agency Inc. Cypen & Cypen South Florida Business Journal Department of Off-Street Parking Southern Wine & Spirits of America, Inc. Entertainment Industry Foundation State Services Systems, Inc. Beatriz Vasquez Federated Department Stores U.S. Grounds Haydee and Omar Vazquez Florida Tropiculture, Inc. Margarita and Clemente Vazquez-Bello Fmsbonds, Inc. Wachovia Wealth Management Andres Vega Four Seasons Palm Beach Resort Waltman & Cohen Paul Wattenberg Fowler White Burnett P.A. Weinstein Mitzvah Foundation, Inc. Winslow-Rubin Communications, Inc. Gerstle, Rosen & Goldenberg, P.A. Eleanor and Norman Weiss Women’s Cancer League of Miami Beach Global Software, Inc. Serena and Richard Werber Image.com Zubi Advertising Services, Inc. Joan and Morton Trilling Tunu Puri Charitable FDN Rita Ullman Norma and Alejandro Varas Werner Family Foundation Tate Enterprises Victoria & Associates J & D Financial Corporation Jerome A. Yavitz Charitable Italicized names—deceased The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Papanicolaou Corps for Cancer Research (As of FY 2007) Named in honor of cancer research pioneer, Dr. George N. Papanicolaou, developer/ founder of the Pap Smear test for cervical cancer, the Pap Corps is a volunteer organization with more than 17,000 members across three South Florida counties that has supported cancer research at the University of Miami for 55 years. Below are the cancer research units currently active. Papanicolaou Corps for Cancer Research Giving Societies Pap Corps Founders The following Founders Society members have contributed $50,000 to $99,999 to the Pap Corps for Cancer Research: Gloria Levine Pap Corps Grand Friends Addison Hunters Run Sonia Mae Gallo Bellaggio Huntington Lakes South Dade Boca Century Ibis Sunshine The following Grand Friends members have contributed $25,000 to $49,999 to the Pap Corps for Cancer Research: Boca Friends Indian Spring Three Islands/Aquarius Royce and Joel Merzon Boca Lago Majestic Isles Township Boca Pointe Mizner Country Club Triangle Pap Corps Friends Boca West Northwest Valencia Falls Cascades Palm Chase Lakes Valencia Isles Palm Isles Valencia Lakes Dorothy Adler/In memory of Abraham Schein Eleanor Kalvin Cascade Lakes Coral Lakes Pointe Valencia Shores Gloria and Ronald Berkowitz Ponte Vecchio Ferne and Stan Emas Marjorie Kaye Eagles Venetian Isles Goldcoast Ponte Vecchio West Villa Borghese Joy Goldstein * One Pap Grand Friend wishes to remain anonymous. The following Friends for Sylvester members have contributed $10,000 to $24,999 to the Pap Corps for Cancer Research: Greater Boca St. Demetrios Woodfield Cindy and Monty Grant Greater Boynton Scott Linett Wycliffe Gail and Steven Harris Hellenic Shelly Rubin Andrea Ioannides/In memory of George Ioannides Henry Lemonik Barbara and Marvin Kushnick Joyce and Hal Levin Mary Pechewlys Eileen and James Penta Sandra Ribolow Genie and Dick Rosenfeld/ In memory of their daughter Julie Remin Marise and Joseph Rudnick Mollie and Sam Rudt Dorothy and Stanley Saft Debbie and Lou Steiner Janice and Stanley Sussman Eunice and Dr. Sydney Taylor Italicized names—deceased Circle of Promise M embers of the Circle of Promise belong to a select and unique group of individuals, distinguished by their generosity and determination to eradicate cancer. The Circle of Promise: helping more people in South Florida survive cancer. Susan Adin Stuart Connor Barbara Greco Irene Luckmann Terry Rabinor Judy Tomita Apolonia Aguiar Sandra and J. Harmon Cook Margaret Grell Barbara and Julio Luis Frank Toppino Carmen and Rosendo Costero William Grimmer Phyllis Markel Linda and Stephen Rathkopf Barbara and Ronald Grudberg J. Peter Martin Howard Rau Marta Torroella-Kouri William Reap Jim Trimble Ruth and Omar Rivero Norma and Alejandro Varas Ileana Rosen Eric Wadsworth Frank Rosenblatt Jay Rossin Frances and George Weinberg Myron Roth Eleanor and Paul Weiner Susan and Mark Rubin Virginia and Williard Wheeler Joel Altman Nieves and Ricardo Alvarez Silvia and Jose Arguelles Fay Aronson Cynthia and Thomas De Lessio Jan Atlas Peggy Behrens Michael Dezertzov John Bennett Margarete Dingeldein Roslyn Bethel Aileen and Stuart Disick Nanci Beyer Paula Drinkut Jeffrey Bloom Jil and David Bockorny Victoria M. Borges Nancy Faga Carol and Paul Fass Carla Feilbach Brad Buchanan Elsie and Newton Burnett Cora and Antonio Calleja Clarence Cameron Carmen and Gerardo Capo Frances and Chester Casanave Dorothy and Francis Cesarano Richard Chervony Richard Childress Katherine Chouinard Frances and Alfred Cianelli Marjorie and Bruce Cohen Patricia and Dan Cohen Quest Lidia Escobar Rena and Lewis Fagen Elizabeth and Edward Brown Carolyn Coleman Nancy and Walter Counts Sanford Feinman Maximilian Feldstein T. Fennell Jr. Ana and Alexander Fonseca Agnes Frank Veldrin Freemon Carol and Mark Fried Dora and Jose Gallart Evelyn Gargano Lois Goldberg Clara Z. Gomez Lisa and David Goodman Jonathan Goodman Brenda and Donald Hagan Charlotte Held Beth Hermelee Marinela Hernandez Nyria and Manuel Herran Jose Hidalgo Paul Himmerlrich Sonia Himmlestein Juliano Ibarra Richard Ingham Myrtle and James Jackson Margaret and Michael Jarsky Elsa Johnson G. Ellen Jordan Lois and Barry Katz Anita and Stanley Kessel Daniel Keyes Florence Kranitz Beatrice and Robert Krantz Frances and Bernard Laterman Isabel and Marvin Leibowitz Robert Levine Virginia and Edwin Lively Florence and David Lovitz Joyce Masso Isabel May Isidra and Jose Mecsery Ignacio Melero Mari and Kyle Meyer David Miller Jill Monash Miriam Morejon Ruby and Winston Nees Justin Niles Bobbi Ocean Helen Olafson Susan Owen Katherine and Joel Parks Esther and Sergio Pereira Nancy and Alberto Perez Cynthia and Andres Perez Patrick Pfeffer John Phillips Deirdra and Joseph Piegari Jorgelina and Jose M. Pinto Sigmund Pockros Martha Popper Carmen and Juan Prieto Mary and William Quesenberry Jane and Edwin Saiontz Leticia Tornes Ana Maria Sanchez Anthony Wise Dolores and Robert Sanchez Mercedes and Juan Yanes James E. Yost Charlotte and Seymour Schwartz Roy Young Gregory Schweitzer Edythe Zowarder Francis Searle Stephen Zuckerman Denise Zitz Ruth Seitlin Leah and Arthur Sekoff Sharon Silver O. Smith Ruth Solly Richard Steinberg Maxine and Eschol Sutton Stanley Tate Gretchen Tatelman Lenna Taylor Allison and Evan Teisch Leslie and Andrew Tell We have made our best effort to make sure all donors were listed for 2006-2007. If we have accidentally omitted anyone, please accept our sincere apology. Karen Tharp The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 33 Facts and Figures Setting New Records U M/Sylvester’s financial and clinical profiles reveal a cancer center that is fiscally sound and growing. Of particular note are growth in net patient revenue (at 46 percent since FY2005), institutional support that funds research, philanthropy (see figure 5, page 35), and outpatient visits and surgical cases. Both facilities in Miami and Deerfield Beach are expanding to meet the needs of increasing patient volume and interest in clinical trials. FINANCIA L PROFI L E — HOSPITA L FY 2005 FY 2006 FY 2007 S o u r c e s o f r e v e n u e (Figure 1) Net patient revenue Other revenue (operating and non-operating) TOTAL REVENUE $149,786,928 1,951,846 $151,738,774 $187,059,770 2,279,874 $189,339,644 $216,890,723 2,319,516 $219,210,239 U s e s o f r e v e n u e (Figure 2) Salaries and related costs Supplies Utilities and maintenance Purchased services Provisions for bad debt TOTAL OPERATING EXPENSE $48,151,353 30,855,897 2,833,120 22,815,550 7,587,289 $112,243,209 $54,670,184 36,172,294 3,441,767 28,661,003 6,830,474 $129,775,722 $64,262,783 43,229,777 2,653,579 38,728,361 8,979,394 $157,853,894 INCOME BEFORE FINANCING COSTS, DEPRECIATION, AND SUPPORT OF ACADEMIC MISSION $39,495,565 $59,563,922 $61,356,345 Financing costs and depreciation Support of academic mission* $8,946,795 $24,079,725 $8,629,967 $32,113,111 $11,850,990 $36,529,469 *Each year the hospital contributes a portion of its net revenues to support the academic mission (research, teaching, and clinical care) of UM/Sylvester and the Miller School of Medicine. FINANCIA L PROFI L E — RESEARCH FY 2005 FY 2006 FY 2007 $870,000 228,408 1,875,049 $2,973,457 $870,000 1,095,381 1,875,000 $3,840,381 $870,000 1,300,000 7,875,200 $10,045,200 $10,487,000 18,300,705 $31,761,162 $10,351,000 28,561,154 $42,752,535 $12,716,000 36,587,608 $59,348,808 U s e s o f f u n d i n g (Figure 4) Cancer-related investigator/research program expenditures from all UM/Sylvester members approximate funds available $24,250,000 Research resources 2,477,358 Infrastructure 2,577,907 TOTAL RESEARCH EXPENSE $29,305,265 $33,500,000 2,839,351 2,800,223 $39,139,574 $46,510,500 $4,008,996 3,292,930 $53,812,426 S o u r c e s o f f u n d i n g (Figure 3) Institutional support Hospital Miller School of Medicine State of Florida Total institutional support Philanthropy* (Figure 5) Cancer-related sponsored program funding from all UM/Sylvester members TOTAL FUNDING *With the exception of sponsored program funding in the form of grants, UM/Sylvester relies most heavily on philanthropic support to fund cutting-edge basic and translational research. Numbers reflect philanthropic support invested in research during the fiscal year; however, Figure 5 reflects actual dollars raised ($28.3 million including Dodson Estate gift of $12.5 million). FINANCIA L PROFI L E — U M / SY L VESTER Total revenue—hospital Total funding—research TOTAL REVENUE (Figure 6) 10 34 Quest FY 2005 $151,738,774 31,761,162 $183,499,936 FY 2006 FY 2007 $189,339,644 42,752,535 $232,092,179 $219,210,239 59,348,808 $278,559,047 The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Facts and Figures Sources of revenue—Hospital USES o f r e v e n u e — H o s p i t a l f i g u r e 1 FY 2 0 0 7 f i g u r e 2 FY 2 0 0 7 $2,319,516 6% 41% 24% $216,890,723 2% 27% Net patient revenue Other revenue (operating and non-operating) Utilities and maintenance Purchased services Provisions for bad debt Salaries and related costs Supplies Sources of funding—Research Uses of funding—Research f i g u r e 3 FY 2 0 0 7 f i g u r e 4 FY 2 0 0 7 $870,000 $1,300,000 6% 8% $7,875,200 $36,587,608 $12,716,000 Hospital Miller School of Medicine State of Florida Philanthropy Cancer-related sponsored program funding from all UM/Sylvester members 86% Research resources Infrastructure Cancer-related investigator/research program expenditures from all UM/Sylvester members approximate funds available Philanthropy* Total revenue—UM/Sylvester f i g u r e 5 FY 2 0 0 5 - 2 0 0 7 f i g u r e 6 FY 2 0 0 5 - 2 0 0 7 $28,285,832* 30 300 20 15 10 $12,696,365 $15,785,832 $10,416,565 5 200 $183,499,936 150 100 50 0 2005 2006 2007 *Reflects actual dollars raised in FY 2007. The $28,285,832 figure includes the $12.5 million Dodson Estate gift. Quest $232,092,179 250 Millions of Dollars Millions of Dollars 25 $278,559,047 0 2005 Total funding—research 2006 2007 Total revenue—hospital The Magazine of the University of Miami Sylvester Comprehensive Cancer Center 10 35 FACTS a n d FIGURES C L INICA L PROFI L E — HOSPITA L FY 2005 FY 2006 FY 2007 Inpatient beds 40 40 40 Surgery suites 4 4 4 Patient volume* (Figure 7) New cancer patients treated at UM Hospital and Clinics 3,253 3,411 3,796 New cancer patients supervised by UM faculty at Jackson Memorial Hospital 2,578 2,413 2,434 Total 5,831 5,824 6,230 1,428 1,588 1,581 Inpatient 8,747 9,232 8,225 Observation 1,603 1,307 1,353 10,350 10,539 9,578 Average daily census 28.4 28.9 26.2 Average length of stay 6.1 5.8 5.2 175,234 173,238 196,895 Inpatient admissions (Figure 8) Hospital days Total Outpatient visits Surgical cases 2,946 2,615 2,721 Patients receiving chemotherapy 11,525 13,534 14,519 Radiation Therapy Procedures 39,724 36,084 37,147 % from Miami-Dade 42% 41% 41% % from Broward 23% 24% 22% % from Palm Beach 21% 21% 22% 4% 4% 3% 11% 10% 12% 111 163 104 81 93 90 192 256 194 Therapeutic 297 424 365 Non-therapeutic 444 680 626 Total 741 1104 991 Patient base demographics % International % Other Clinical trials underway** Therapeutic Non-therapeutic Total Clinical trial accruals *Patient volume as reported to the State of Florida as of September 2007; data are one year behind and correspond to the calendar, not the fiscal, year. New patient volume—Hospital i n p a t i e n t a dm i s s i o n s — H o s p i t a l Figure 7 FIG U RE 8 FY 2 0 0 5 - 2 0 0 7 CY 2005-2007 (Reported to the State of Florida as of September 2007; data are one year behind) 2,000 8,000 5,831 5,824 6,230 Admissions Patients 6,000 1,750 4,000 1,500 1,000 0 750 2006 Quest 2006 2007 1,428 2007 New cancer patients supervised by UM faculty at Jackson Memorial Hospital New cancer patients treated at UM Hospital and Clinics 10 36 1,581 1,250 2,000 2005 1,588 0 2005 The Magazine of the University of Miami Sylvester Comprehensive Cancer Center Quest Editor Felicia Lopez-Walker, M.S.B. Direct inquiries to: UM/Sylvester Marketing and Design Sabia Communications Inc. Communications 1475 N.W. 12th Avenue, Suite C001 Published by the Office of Marketing Miami, Florida 33136 and Communications for patients, Telephone: 305-243-4302 donors, and friends of the University of Fax: 305-243-4146 Miami Sylvester Comprehensive Cancer E-mail: flopez1@miami.edu Center. All contents ©2008, University of Miami. Contents may be reproduced by permission from the editor and if appropriate credit is given. Patient Privacy Protected The University of Miami is committed to protecting the information of its patients. A central privacy office has been established to promote a culture of privacy at the University of Miami. If you do not wish to receive Quest in the future, please send your request in writing to the University of Miami Office of HIPAA Privacy and Security, P.O. Box 019132 (M-879), Miami, Florida 33101. We have a standard letter that you can fax back if that is more convenient. 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