Welding fume exposure and determinants in German male
Transcription
Welding fume exposure and determinants in German male
Welding fume exposure and determinants in German male welders Benjamin Kendzia1, Anne Lotz1, Martin Lehnert1, Tobias Weiss1 , Katarzyna Gawrych1, Evelyn Heinze1, Ying Chen1, Rainer Van Gelder2, Markus Berges2, Thomas Brüning1, Beate Pesch1 and the WELDOX Study Group 1 2 Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany Institute for Occupational Safety and Health of the German Social Accident Insurance (IFA), Sankt Augustin, Germany Results and discussion Introduction and objectives Various studies investigated exposure to particulate mass among welders (Hobson et al. 2011). However, studies measuring respirable welding fumes in the breathing zone of welders are rare. The aim of this analysis was to explore exposure to respirable welding fumes and potential influencing factors of the airborne concentrations. Methods Conclusions » Among 241 measurements of respirable welding fumes from the WELDOX study, 90 data points were below LOD. » Two different approaches were applied to deal with data below LOD, Tobit regression and imputation. They revealed similar effect estimates for potential determinants of the exposure to welding fume and yielded a good model fit. » The welding process was the major determinant, with high concentrations for FCAW and considerably lower concentrations for TIG in terms of particulate mass. Efficient LEV reduced exposure, working in a confined space increased the exposure significantly. Figure 1: Welder working in confined space Figure 2: Welder using efficient local exhaust ventilation Table 1: Potential determinants of exposure to respirable welding fume (N=215; excluding users of powered air-purifying respirators) Factor N Tobit regression Exp(ȕ) 95% CI N<LOD Intercept [mg/m³] Gas metal arc welding Flux-cored arc welding Tungsten intert gas welding Shielded metal arc welding Miscellaneous Multiple imputation Exp(ȕ) 95% CI 2.84 2.30 - 3.50 2.54 1.87 - 3.44 78 42 66 17 12 9 0 47 8 1 1.00 2.17 0.18 1.02 1.12 1.57 - 3.00 0.12 - 0.27 0.60 - 1.73 0.66 - 1.90 1.00 2.36 0.16 0.87 1.39 1.49 - 3.72 0.10 - 0.27 0.41 - 1.86 0.66 - 2.93 Mild steel Stainless steel Miscellaneous 79 109 27 5 57 3 1.00 0.49 0.90 0.36 - 0.68 0.63 - 1.29 1.00 0.45 0.95 0.29 - 0.70 0.58 - 1.57 Non-confined space Confined space 193 22 65 0 1.00 1.63 1.10 - 2.42 1.00 1.83 1.06 - 3.14 Non-efficient local exhaust ventilation 167 47 1.00 0.32 - 0.63 1.00 48 18 0.45 0.32 - 0.63 0.41 Efficient local exhaust ventilation 0.73A Model fit R² Major determinant of the concentrations was the type of welding process. The use of flux-cored wire in gas metal arc welding (FCAW) was estimated to increase the concentration in comparison with gas metal arc welding with solid wire (GMAW) by a factor of 2.17 (95% CI 1.57-3.00) using Tobit regression and by 2.36 (95% CI 1.493.72) using imputation. Tungsten inert gas welding (TIG) was associated with 0.18 or 0.16 fold lower exposure levels than with GMAW in both models. Welding of stainless steel was associated with significant lower concentrations in comparison to mild steel. Efficient LEV reduced the concentrations and welding in confined space increased exposure levels with significant effects in both approaches. References • Efron B (1979) Bootstrap methods; another look at the jacksknife. Ann Statistics 7: 1-26 • Harel O (2009) The estimation of R2 and adjusted R2 in incomplete data sets using multiple imputation. Journal of Applied Statistics 36: 1109-1118 • Hobson A, Seixas N, Sterling D, Racette BA (2011) Estimation of particulate mass and manganese exposure levels among welders. Ann Occup Hyg 55: 113-125 • Laitila T (1993) A pseudo-R2 measure for limited and qualitative dependent variable Models. Journal of Econometrics 56: 341-356 • Lubin JH, Colt JS, Camann D, Davis S, Cerhan JR, Severson RK, Bernstein L, Hartge P (2004) Epidemiologic evaluation of measurement data in the presence of detection limits. Environ Health Perspect 112: 1691-1696 • Tobin J (1958) Estimation of relationship for limited dependent variables. Econometrica 26: 24-36 0.25 - 0.66 0.64B A Laitila 1993, B Harel 2009 " !$#% WELDOX was conducted as nationwide study among welders in German industries. Personal sampling of respirable welding fumes was carried out in 241 welders. Exposure to particle-size specific welding fumes was determined by personal sampling in the breathing zone inside the helmets during a working shift. Experienced technicians documented the welding techniques, the workplace characteristics, and other exposurerelated conditions. In addition, photos were taken to document the workplaces. Ninety measurements of respirable welding fumes were below limit of detection (LOD). Therefore, we applied Tobit regression (Tobin 1958) and imputations of values <LOD with a maximum likelihood estimation method (Lubin et al. 2004, Efron 1979). Assuming an equal probability distribution below and above LOD we imputed values <LOD randomly from a log-normal distribution (1000 runs). We presented regression coefficients for the welding processes, materials, working in confined space, and using efficient local exhaust ventilation (LEV) at the original scale. Figure 3: Respirable welding fume by welding process. FCAW = GMAW = TIG = SMAW = Flux-cored arc welding, Gas metal arc welding, Tungsten intert gas welding, Shielded metal arc welding Acknowledgement: WELDOX was financially supported by the German Social Accident Insurance (DGUV).