13th Annual Meeting of the ECNM

Transcription

13th Annual Meeting of the ECNM
Welcome to Munich
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We would like to thank our sponsors
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Legal Disclaimer
Neither the organizer nor EUROKONGRESS GmbH shall be liable for accidents, bodily injury, theft as well as
for additional costs due to the change of event date, location, program or similar. Liability for additional costs
due to delays, changes or cancellations of flights, trains or other means of transport as well as due to strike
action, illness, weather or environmental disasters is also excluded. It is the responsibility of each participant
to arrange appropriate theft-, accident-, health as well as travel cancellation insurance. Participants as well as
accompanying persons take part at their own responsibility and risk.
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Prof. Dr. med. Karl Sotlar Karl.Sotlar@med.uni-muenchen.de
Prof. Dr. med. Hans-Peter Horny Hans-Peter.Horny@med.uni-muenchen.de
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Institute of Pathology – Ludwig-Maximilians-Universität München
Thalkirchner Str. 36
80337 Munich, Germany
M
Gaig
Organizer
.
13th Annual Meeting of the ECNM
Munich, October 8 -10, 2015
Program Thursday, October 8
13:30 Welcome Coffee
14:00 Karl Sotlar & Hans-Peter Horny (Munich, Germany)
Welcome
14:10 Thomas Kirchner (Munich, Germany)
Welcome Notes
14:25 Emir Hadzijusufovic (Vienna, Austria)
ECNM Homepage
14:30 Michel Arock (Paris, France) & Peter Valent (Vienna, Austria)
Status of the ECNM in 2015
Session II: Mast Cell Activation and Allergy in Mastocytosis
Chairs: B. Nedoszytko & L.B. Schwartz
17:15 Sigurd Broesby Olson (Odense, Denmark)
Diagnostic Algorithm for Patients with Suspected Mastocytosis
17:30 Patrizia Bonadonna (Verona, Italy)
Hymenoptera Venom Allergy in Clonal Mast Cell Disorders
17:45 Hanneke Oude-Elberink (Groningen, Netherlands)
Treatment of IgE-Dependent Allergy in Mastocytosis
18:00 Cem Akin (Boston, USA)
Mast Cell Activation Syndrome: Update 2015
18:15 Boguslaw Nedoszytko (Gdansk, Poland)
Genetic Patterns Predisposing to Anaphylaxis in Mastocytosis
20:00 Faculty Dinner
14:40 Peter Valent (Vienna, Austria) & Michel Arock (Paris, France)
Presentation of the Researcher of the Year 2015
14:45 Lawrence B. Schwartz (Richmond, VA, USA)
Development of Tryptase as Biomarker in Mastocytosis
15:15 Coffee Break
Session I: Skin and Childhood Mastocytosis
Chairs: K. Brockow & C. Akin
15:45 Karin Hartmann (Cologne, Germany)
Heterogeneous cutaneous lesions in childhood-onset
mastocytosis
16:00 Luis Escribano (Madrid, Spain)
Lesional Patterns of CM in Children and Clinical Implications
16:15 Knut Brockow (Munich, Germany)
Treatment of Cutanous Mastocytosis in Children and Adults
16:30 Franziska Ruëff (Munich, Germany)
Management of Anaphylaxis in Mastocytosis
16:45 Coffee Break
Program Friday, October 9
8:10 Welcome Coffee
Session III: Presentation of ECNM Registry Projects
Chairs: P. Valent & W.R. Sperr
8:30 Wolfgang R. Sperr (Vienna, Austria)
Introduction and Presentation of Pilot Project:
IPSS for mastocytosis
8:40 Anja Rabenhorst & Karin Hartmann (Lübeck, Germany)
Age-Adjusted Diagnosis and Prognostication in Mastocytosis
8:50 Massimo Triggiani (Salerno, Italy)
Spectrum of Mediator-Related Symptoms in Mastocytosis
9:00 Hanneke Kluin-Nelemans (Groningen, Netherlands)
Clinical significance of blood count abnormalities in mastocytosis
9:10 Marek Niedoszytko & Boguslaw Nedoszytko (Gdansk, Poland)
Impact of allergic disorders and anaphylaxis in mastocytosis
9:20 Andreas Reiter & Juliana Schwaab (Mannheim, Germany)
Impact of serum chemistry on diagnosis and treatment of
systemic mastocytosis
9:30 Serena Merante (Pavia, Italy)
Treatment of patients with mastocytosis: comparison of
response rates
9:40 David Fuchs & Rosemarie Greul (Linz, Austria)
Risk of SM in patients with MIS
9:50 Roberta Zanotti & Patrizia Bonadonna (Verona, Italy)
Impact of bone marrow mastocytosis (BMM)
10:00 Nadja Jäkel (Leipzig, Germany)
Clinical impact of serum tryptase levels in the FU in SM
10:10 Elisabeth Aberer (Graz, Austria)
Skin lesion in different categories of mastocytosis
10:20 General open discussion of individual projects
Session V: Hot Topics in Mastocytosis
Chairs: J. Gotlib & K. Brockow
14:00 Joanna Renke & Magdalena Lange (Gdansk, Poland)
Antibody deficiencies in children with mastocytosis –
a new face of the disease?
14:15 Jaap J. Doormaal (Groningen, Netherlands)
Diagnosis and Management of Osteopathy in Mastocytosis
14:30 Michel Arock (Paris, France)
KIT Mutation Analysis: Proposed Standards and Algorithm of
the ECNM
14:45 Olivier Hermine (Paris, France)
Mental and Psychiatric Problems in Mastocytosis: Diagnosis
and Management
15:00 Almundena Matito (Salamanca, Spain)
Familial Mastocytosis and Management of Mastocytosis in
Pregnancy
15:15 Melody Carter (Bethesda, MD, USA)
tba
15:30 Coffee Break
Session IV: Pathology
Chairs: H. Kreipe & H.-P. Horny
11:30 Dan Arber (Stanford, USA)
Myeloid neoplasms: News from the WHO classification system
12:00 Hans Kreipe (Hannover, Germany)
Eosinophils and Mast Cells in the Neoplastic Bone Marrow
12:15 Sigrid Regauer (Graz, Austria)
Mast cells in pain disorders (vulvodynia, chronic bladder pain)
and in lichen planus
12:30 Hans-Peter Horny (Munich, Germany)
Unusual Cases: Mimickers and Chameleons in SM
Session VI: Basic Science and Cell Research
Chairs: A. Reiter & M. Triggiani
16:00 Animesh Pardanani (Rochester, MN, USA)
Mastocytosis research update from Mayo Clinic
16:15 Harald Bartsch (Munich, Germany)
MicroRNA expression profiles in mastocytosis
16:30 Thomas K. Kristensen (Odense, Denmark)
Targeted ultra-deep next generation sequencing as a method for
KIT mutation analysis in mastocytosis
16:45 Andreas Reiter (Mannheim, Germany)
Mutational Profiles of CFU-GM in various Categories of SM
17:00 Gunnar Nilsson (Stockholm, Sweden)
Mast cells and mediators in mastocytosis
17:15 Michael Huber (Aachen, Germany)
Positive and Negative Control of IgE-dependent MC Activation
17:30 Ivan Alvarez-Twose (Toledo, Spain)
Diagnosis and classification of well-differentiated
systemic mastocytosis
17:45 Olivier Hermine (Paris, France)
Masitinib for the treatment of severe systemic mastocytosis:
Pooled phase 2 study simulation of phase 3 population and
response criteria
18:00 Stéphane Barete (Paris, France)
Treatment with Cladribine (2-CdA) in adult patients with
mastocytosis
12:45 Lunch Break
20:00 Dinner (Der Pschorr, Viktualienmarkt)
10:30 Coffee Break
10:30- Registry Steering Committee Meeting (closed)
10:50 Discussion and Nomination of ECNM Registry Projects (closed)
Program Saturday, October 10
8:15
Welcome Coffee
Session VII: Proposed Clinical Studies: New Trials and Updates
Chairs: L. Escribano & K. Hartmann
8:30 Frank Siebenhaar (Berlin, Germany)
Clinical Trials to Control Mediator-Related Symptoms
8:45 Bernd Jilma (Vienna, Austria)
Proposed DAO Trial in Patients with SMSY
9:00 Serena Merante (Pavia, Italy)
JAK2-Inhibitors in Mastocytosis
9:15 Bjorn van Anrooij (Groningen, Netherlands)
Clinical Trials with PKC412 in ISM
9:30 Jason Gotlib (Stanford, CA, USA)
Update of PKC412 Trials in Advanced SM and MCL
9:45 Sigurd Broesby Olson (Odense, Denmark)
Targeted Approaches to control IgE-dependent
Reactions in Mastocytosis
Session IX: Late Breaking Abstracts
Chairs: M. Arock & K. Sotlar
12:30 Vito Sabato (Antwerpen, Belgium)
Update of Familial Hypertryptasemia
12:45 Selim Yavuz (Istanbul, Turkey)
Chronic Mast Cell Leukemia
13:00 Martin Zenke (Aachen, Germany)
Induced Pluripotent Stem Cells (iPSC) for Disease Modeling
in SM
13:15 Deepti Radia (London, U.K.)
Management of Patients with Mastocytosis in the U.K.
13:30 Judit Varkonyi (Budapest, Hungary)
Neoplastic and non-neoplastic comorbidities in systemic
mastocytosis
13:45 Francesca Levi-Schaffer (Jerusalem, Israel)
Mast Cell-Eosinophil Interactions in Health and Disease
14:00 Mariana Castells (Boston, MA, USA)
Drug Reactions in Mastocytosis: Is Pretesting useful?
10:00 Coffee Break
14:15 Closing Remarks and Announcements
Session VIII: Proposed Basic Science and Translational Projects
Chairs: G. Nilsson & K. Sotlar
10:30 Olivier Hermine (Paris, France)
ECNM Application Proposal: Horizon 2020
10:45 Carlo Pucillo (Udine, Italy)
MANTRA: Presentation of Concept
11:00 Celalettin Ustun (Minneapolis, MN, USA)
Occult Mastocytosis and KIT D816V in CBF AML
11:15 Frank Siebenhaar (Berlin, Germany)
EMBRN and other Basic Science Networks in the EU
11:30 Peter Valent (Vienna, Austria)
Presentation of a Basic Science Network-Section of the ECNM
11:45 General Discussion
12:00 Coffee Break
14:30 End of Meeting