Document 6424816
Transcription
Document 6424816
Dear members, dear colleagues, dear friends, I am proud to present to you today the programme for our European Congress of Aerospace Medicine “ ECAM - 2008”. My special thanks go to our Hungarian colleagues and the ESAM conference committee who made this congress possible. It is proof of how cooperation between the European aerospace medicine associations can lead to an exchange of scientific and practical knowledge of the highest international standard. Roland Vermeiren President of ESAM From the ideas of a few pioneers on the need for a common European Society of Aerospace Medicine - just 3 years ago - to the ESAM of today with its 31 member associations representing about 3,400 professionals, impressive progress has already been made. We are now legally registered, have our website, our scientific advisory board, meetings at international congresses and are now also holding our congress. In the meantime we are developing close relations with our international friends such as AsMA and IAASM. It is our common task to further develop ESAM into a strong and acknowledged scientific and pan-European partner with a view to improving the safety and health of all involved in aviation and space operations. We can do it if we work together. Kind regards, amicaliter, ESAM The European Society of Aerospace Medicine Under the Patronage of Distinguished Ladies and Gentlemen, We would like to extend our warm welcome to all the participants of the ESAM Budapest. Since 1993 Hungary hosted a number of significant meetings on the field of Aerospace Medicine, the National Transport Authority is proud to support this Conference as well. We hope that this meeting will provide all of You again the best of Science with the well-known Hungarian hospitality. Zsolt Csaba Horváth President National Transport Authority József Vágó Director Directorate of Air Transport The Exclusive Sponsor of European Conference on Aerospace Medicine Budapest 2008 Dear Delegates, On behalf of HungaroControl Hungarian Air Navigation Services Pte. Ltd. Co. – as the exclusive sponsor of the event – I am glad to welcome you at the European Conference on Aerospace Medicine in Budapest. I hope that with our support the efforts of the Association of Hungarian Aerospace Medicine will result in a successful professional gathering. Dr. Laszlo Kiss I understood that at this year’s conference you have a special focus on the medical issues regarding the air traffic control operations. As part of our Corporate Social Responsibility Program, HungaroControl strives to ensure to its employees the access to the highest level of medical attention. This year we have taken a new initiative by extending this service to the field of psychological assistance in handling stress. CEO HungaroControl Pte. Ltd. Co. I hope that besides the professional program you will also have a chance to see some of the sights of our beautiful capital, and enjoy the famous Hungarian hospitality. I wish you a successful conference and a great time in Hungary. Best regards, Dr. Laszlo Kiss CEO HungaroControl Pte. Ltd. Co. European Conference on Aerospace Medicine 12th – 15th November 2008 BUDAPEST ECAM Scientific Conference Thursday 13th November 2008 Registration 08:00 - 18:00 HungaroControl Conference Centre 9:00 - 9:30 Opening Ceremony 9:45 – 11:00 Keynote Presentations Chair: H. Pongratz G. Hardicsay No 1. PANDEMIC PREPAREDNESS PLANNING IN AVIATION – THE ROLE OF AIRPORT PERATORS W Gaber, R.Gottschalk No 2. CORONARY REVASCULARISATION 2008. - OVERVIEW David Becker and Béla Merkely 11:00 – 11:30 Break 11:30 – 13:00 Passenger health and medical evacuation Chair: M. Bagshaw and S. Ries No 3. DOC ON BOARD - MEDICAL EMERGENCIES ON BOARD COMMERCIAL AIRCRAFT J. Huber, G. Huber, D. Gabriel No 4. LESS HYPOGLYCEMIC EVENTIS WITH EXENATIDE IN TYPE 2 DIABETES F. Strollo, M. Morè, M. Corigliano, G. Corigliano and G. Strollo No 5. AIR EVACUATION UNDER BIOSAFETY CONTAINMENT OF PATIENTS WITH HIGHLY CONTAGIOUS INFECTIOUS DISEASES M. Lastilla, P. Tosco, R. Biselli, O. Sarlo No 6. FAINTING PASSENGERS: THE ROLE OF CABIN ENVIRONMENT R. Simons, H. de Ree No 7. THE AEROTOXIC SYNDROME M. Bagshaw No 8. THE PERFORMANCE OF BLOOD PRESSURE MEASURING DEVICES AT GROUND LEVEL AND AT 8,000ft M. F. Hudson 13:00 – 14:00 Lunch 14:00 – 15:30 Aircrew health I Chair: C. Stern, H.-W. Teichmüller No 9. WOULD YOU FLY WITH THIS PILOT AFTER TRAUMATIC BRAIN INJURY (TBI) A. Martin St Laurent No 10. FUNDUS IMAGING IMPROVES EFFICACY AND SAFETY OF MEDICAL EXAMS R. Quast, H. Wilhelm No 11. VISUAL OUTCOME AFTER CORNEAL REFRACTIVE SURGERY C. Stern, G. Kluge No 12. CORNEAL REFRACTIVE SURGERY AMONG HUNGARIAN PILOTS FROM 2001 TO 2008 L. Ungváry No 13. MESOPIC CONTRAST SENSITIVITY IN A YOUNG POPULATION B. Haughom, T.-E. Strand, I. Berg No 14. AEROMEDICAL CERTIFICATION IN PROGRESSIVE MITRAL VALVE PROLAPSE E. Cataman, A. Batrinac 15:30 – 16:00 Coffee break 16:00 – 17:00 Aircrew health II Chair: L. Tjensvoll, E. Cataman No 15. OVERWEIGHT IN MILITARY PILOTS AND WSOS IN GERMANY 1977-2006 H. Glaser No 16. FRAMINGHAM CORONARY RISK FACTORS AT MALE AVIATION PERSONNEL – COMPARISON WITH NON AVIATION POPULATION IN SLOVAK REPUBLIC P. Daxner No 17. PSYCHOLOGICAL DIAGNOSTICS OF FOREIGN AIR STAFF IN AIR MILITARY HOSPITAL J. Mayerova, E. Slovenska, M. izmárik No 18. NEUROCOGNITIVE PERFORMANCE IN AIRCREW IN TREATMENT WITH ANTIDEPRESSANT SSRIS AND SNRIS S. Izzo,. G. Arduino, E. Velardi,. S. Mosticoni 17:00 – 18:00 Poster – Inspection & Discussion Friday 14th November 2008 Registration 08:00 - 18:00 HungaroControl Conference Centre 9:00 – 10:30 Hypoxia Chair: A. Wagstaff, H. Pongratz No 28. CONSIDERATIONS CONCERNING PRACTICAL HYPOXIA TRAINING FOR COMMERCIAL AIRCREW R. Simons (Intro by Virgilijus Valentucevicius ESAM) (30 min and 15 min discussion) No 29. CARDIAC ARREST DURING HYPOBARIC CHAMBER EXPOSURE AT A YOUNG PILOT M. Anghel, I. Capanu, M. Muresan No 30. RESISTANCE ASSESSMENT TO HYPOBARIC-HYPOXIC STRESS THROUGH SIMULTANEOUS MONITORING OF THE ECG RECORDING AND OXYGEN SATURATION I. Capanu, D. Vlad, S. Berbecar No 31. HYPOXIA AWARENESS: THE PRESENT AND FUTURE OF HYPOXIC TRAINING OF HUNGARIAN MILITARY AIRCREW S. Szabó, A. Grósz, Zs. Tótka 10:30 – 11:00 Coffee Break 11:00– 12:30 Regulations Chair: R. Vermeiren, V. Valentukevicius No 23. MEDICAL REQUIREMENTS FOR LEISURE PILOT LICENCE V. Valentukevicius (with discussion 30 min) No 24. IMPLEMENTATION OF EU DIRECTIVE « NOISE » INTO GERMAN LAW AND CONSEQUENCES FOR FLIGHT CREWS D.-M. Rose, H.-J. Kimpflinger, M. Vierdt, J. Hedtmann No 25. EVALUATING WHOLE BODY VIBRATION LEVELS IN MILITARY AND CIVILIAN HELICOPTERS ACCORDING TO LEVELS DEFINED BY EC (2002/44/EC) J. I. Kåsin, A. Wagstaff No 26. NEW REGULATIONS OF EASA NPA 2008-17C, PRACTICAL OPHTHALMOLOGICAL ASPECTS G. van Setten No 27. THE ‘IRISH’ VIEW ON THE NEW REGULATIONS FOR MEDICAL CERTIFICATION. WILL IT ALL CHANGE? A. Roodenburg 12:30 – 13:30 Lunch 13:30 – 14:30 Special senses and aviation medicine Chair: A. Wagstaff, G. Hardicsay No 19. VESTBULAR ANALYZER AND DESORIENTATION IN SPACE OF MILITARY PILOTS M. Spahieva, L. Aleksiev, A. Petkov, K. Kanev No 20. THE ITALIAN AIR FORCE (ITAF) EXPERIENCE ON SPATIAL DISORIENTATION TRAINING M. Lucertini, P. Trivelloni, O. Sarlo No 21. TINNITUS AND HEARING IN A NORWEGIAN AIRLINE PILOT POPULATION A. S. Wagstaff, P. Blum No 22. EFFECTS OF HYPOXEMIC HYPOXIA ON PATTERN REVERSAL VISUAL EVOKED POTENTIALS (VEPs) D. di Blasio, G. C. Appiani, A. Carboni, N. Pescosolido 14:30 – 15:00 Break 15:00 – 16:30 Would You Fly with this Pilot? Case discussions’ Moderator: Gabor Hardicsay 16:30 – 16:45 Closing Remarks Posters Thurday / Friday 13th -14th November 2008 Registration 08:00 - 18:00 HungaroControl Conference Centre No 32. ASSESSMENT OF PUSH-PULL EFFECTS: A NEW PROCEDURE BASED ON A TEXTILE WEARABLE SYSTEM FOR VITAL SIGNS RECORDING A. G. Guadagno, S. Cacopardo, P. Trivelloni, F. Rizzo, P. Meriggi, M. di Rienzo No 33. INJURY- AND FATALITY-RATES IN GERMAN GENERAL AVIATION ACCIDENTS – A FIVE YEAR REVIEW C. Neuhaus, M. Dambier, E. Glaser, J. Hinkelbein, H. Pongratz No 34. ADVANCED CORONARY DIAGNOSTICS: MULTI-DETECTOR COMPUTER TOMOGRAPHY (MDCT) TO DIAGNOSE CORONARY HEART DISEASE (CHD) IN MILITARY PILOTS C. Wonhas, J. Hausleiter, C. Ledderhos, S. Martinoff, A. Schömig No 35. DEVELOPING A METHOD FOR THE QUANTITATIVE ASSESSMENT OF G-MEASLES C. Ledderhos, B. Debrabant, K. Debrabant, R. Mörlin, A. Gens No 36. COMPARISON OF STUDIES ON GENERAL AVIATION ACCIDENTS IN DIFFERENT COUNTRIES USING THE HFACS MODEL C. J. Hinkelbein, M. Dambier, E. Glaser, C. Neuhaus, H. Pongratz No 37. A SIMPLE TECHNIQUE FOR GRAVITY SIMULATION (+1GZ, 0GZ, AND -1GZ) DEMONSTRATES COMPROMISED LUNG FUNCTION C. Neuhaus, M. Dambier, E. Glaser, J. Hinkelbein, H. Pongratz No 38. POSSIBILITIES FOR THE DETECTION OF IN-FLIGHT HYPOXIA – PULSE OXIMETRY C. Ledderhos, A. Gens, G. Rall No 39. MEASURING PSYCHIC STRESS WITH BIOLOGICAL DATA A. Grósz, E. Tóth, Á. Szatmári No 40. SIGNAL DETECTION IN HYPOBARIC HYPOXIA - A STRESS SITUATION A. Grósz, E. Tóth, Á. Szatmári No 41. MARKOV STATE TRANSITION MODELS FOR THE PREDICTION OF CHANGES IN SLEEP STRUCTURE INDUCED BY AIRCRAFT NOISE M. Basner, U. Siebert No 42. THE PROBLEM OF A“HUMAN FACTOR” UNDER EXTREME AVIATION CONDITIONS S. T. Mammadova No 43. PRECANCEROUS SIGNS IN THE MOUTH DETECTED DURING MEDICAL FITNESS EXAMINTIONS OF COCKPIT AND CABIN CREWS Z. Pácz, I. Melles No 44. STRESS RELATED SYNDROMES: A NEW NOSOGRAPHIC APPROACH TO THE PSYCHIATRIC DISFUNCTIONS IN AIRCREW G. Arduino, S. Izzo, D. Abbenante No 45. RESPIRATORY CO2, AS A PHYSIOLOGICAL AND NEURAL-PERCEPTION INDICATOR OF PILOTS’ VISUAL MANAGEMENT, IN AVIATION-A REVIEW. J. Sharma ABSTRACT No 1. Title: PANDEMIC PREPAREDNESS PLANNING IN AVIATION – THE ROLE OF AIRPORT OPERATORS Author(s) Name: W GABER (1), R.GOTTSCHALK (2) Introduction: Pandemics move as fast as the vectors that spread them. In the case of human infectious diseases, spread via ships has been replaced almost completely by todays air traffic. Therefore public health services across the world must focus their attention on the problem of epidemics being spread via this means of transport. The global reach of flight connections is based on many non-stop routes and only a few so-called hubs where up to 50% of their passengers connect. These hubs thus represent the pivotal points in international air traffic. Methods: Since the main risk of pandemic influenza was, and remains, centred in Asia, the initial work was undertaken in this region. A workshop was held in Singapore that brought together representatives from different expert groups to develop a preparedness plan, including the WHO, ICAO, IATA, CDC, FAA, ECAC and ACI. Work under the leadership of ICAO has now also commenced in Africa and will be extended to Europe. Results: Guidelines for developing a national preparedness plan for aviation were developed that coordinated the views of several different organizations. In particular, it was found that communication and coordination between the national public health and aviation authorities is essential to develop a satisfactory national preparedness plan, but in most States is still not adequately developed. The role of the World Health Organization International Health Regulations (2005) was found to be especially important. Conclusion: The concept of management of highly contagious and life-threatening diseases must continuously be adjusted to the specific circumstances of air traffic. Apart from development of procedures and checklists for all involved in the process, the provision of quarantine places in a sufficient number (scenario: Airbus A 380 X, > 550 passengers; one patient suspected of having a highly infectious disease) is a necessity. Regular national and international exchange of coordinated information is essential and should be organized under the auspices of the WHO. Consequences of public health measures are immense and will quickly overwhelm even a major airport and the logistics of the health authorities. Name and address for correspondence: Dr. W. Gaber, Fraport AG, 60547 Frankfurt Airport Telephone No.: 069-690-66031 Fax No.: 069-690-59642 E-mail: w.gaber@fraport.de Date: 12.08.2008 ABSTRACT No 2. Coronary revascularization 2008 - Overview A uthor(s) Name: David Becker and Béla Merkely Semmelweis University Heart Center, Budapest, Hungary Introduction: Coronary artery disease is a leading cause of mortality and morbidity in the developed world. Treatment of ischemic heart disease/coronary artery disease consists of adequate primary and secondary prevention, control of symptoms (e.g. medications, as well as PCI or CABG for angina) and in acute cases (like STEMI/NSTEMI) urgent revascularization of stenosed/occluded coronary vessels. Risk factors of coronary artery disease have to be examined and treated even in asymptomatic individuals with lifestyle-changes and medications. After suffering an acute ischemic event, secondary prophylaxis is needed with more strict decreases in blood pressure and lipid levels along with lifestyle changes. Not only lifestyle changes and medications are available for these patients as mentioned earlier. Revascularization with the implantation of stents (PCI) or by CABG surgery can be offered for these patients, as well. Methods and Results: We can separate the patients according to their clinical presentation, and so we might divide them into three major groups. 1: Stable symptoms (effort angina, dyspnea etc.); 2. UA/NSTEMI; 3. STEMI patients. There is a different approach in all three patient groups. Group 1: Coronarography might be indicated for diagnostic purposes (according to the ESC Guidelines, 2007). Class I. indications are (level of evidence): EAP CCS III, high probability of CAD, especially if not adequately responding to meds (B); Survivors of cardiac arrest (B); Serious ventricular arrhythmia (C); Previous PCI or CABG and moderate or severe EAP (C). High risk patients by noninvasive tests, even if mild or moderate symptoms (B); EAP CCS III, high probability of CAD, especially if not adequately responding to meds (B); Prior to major surgery, especially vascular ones with intermediate or high risk features on noninvasive tests (B). Class IIa. indication (level of evidence): Inconclusive noninvasive test(s), mod-high probability of CAD (C); Patients with high risk of restenosis after PCI with important site prognostically (C). Coronarography might be indicated for risk assessment in this patient group. After the invasive test, a decision can be made regarding revascularization strategy – either PCI or CABG can be used, according to the number of involved vessels, the presence or absence of diabetes and whether normal or decreased left ventricular function is present. The decision is influenced also by patient comorbidities (general status for surgery) and the patient wishes. The role of PCI in stable, effort angina patients vs optimal medical therapy was looked at by the COURAGE trial which showed equal results with medical treatment regarding risk of death, myocardial infarction, or other major cardiovascular events, however less angina and less subsequent revascularization was present in the PCI group during follow-up. Another study, the Syntax study evaluated patients with LM (+1, 2 or 3 vessel) and triple-vessel disease (without LM involvement) who underwent either drug eluting stent(s) implantation or CABG surgery. The only significant differenc was a decreased risk of stroke in the PCI gourp at 1 year, but an incresed risk of repeat revascularization in the PCI group. This brought total MACCE events in favor of CABG surgery mainly driven by the high repeat revascularization in the PCI group. On the other hand, if one looked at LM and LM+1 vessel disease, one year outcome was better for the PCI group. In diabetics, CABG was more favorable. Group 2: (UA/NSTEMI) coronarography/PCI is indicated by the ESC Guidelines according to the clinical scenario, by using certain criteria (e.g. ongoing/recurrent ischemia; malignant arrhythmia or hemodynamic instability makes a patient high risk; while the presence of decreased ejection fraction, prior revascularization, positive Troponin, renal inssufficiency etc. moves the patient into the moderate risk group), we can risk stratify the patient into high, moderate or low risk. In the first group urgent coronarography/PCI isr ecommended; in the second group it is indicated within 72 hours, while in the low risk group an invasive strategy should be followed only if ischemia is proven. Group 3: STEMI patients should be treated by PCI if symptoms are within 12 hours and it can perfomed within 90 minutes. Exceptions are patients with cardiogenic shock, where PCI can be performed if symptom onset is within 36 hours. After thrombolysis a coronarography is indicated. If the lysis is successful, then within 24 hours; if unsuccessful, then as soon as possible. Follow-up Regular follow-up with exercise stress test is indicated at 1-3-6-12 months and then yearly, unless symptoms develop. Echocardiography is indicated according to the patient clinical condition and prior echocardigoraphy results. Name and address for correspondence: David Becker, Semmelweis University Heart Center, 1122. Városmajor u. 68 Budapest, Hungary Telephone No.: +36-1-458-6810 Fax No.: +36-1-458-6842 E-mail: becdavid@gmail.com Date: 15.09.2008 ABSTRACT No 3. Title: DOC ON BOARD - MEDICAL EMERGENCIES ON BOARD COMMERCIAL AIRCRAFT Author(s) Name: Joachim Huber, Gustav Huber, David Gabriel Introduction: At this very moment, approx. 1 million people around the world are in the air. IATA airlines transport 2,000 million people annually. The total number of fatalities on the 250 IATA airlines is approx. 2500 a year.In spite of this, there has been no emergency medical provision un now for the approx. 350 passengers who suffer acute illnesses each day. Methods: What are the most common emergencies? What equipment is available on board? What is the legal position? How do flight crews regard medical emergenc and communication with these assistants? Are these assistants (physicians/emergency paramedics) authorised to request a stopover? Who bears responsibility and who meets the costs? What is the limit of the paramedics’ competence in an emergency? Results: In 2004, MTE - Medical Training Europe – initiated the “DOC ON BOARD” project in collaboration with Austrian Airlines. Physicians and emergency paramedics are specially trained to deal with medical emergencies on board and are available to provide skilled assistance to crews even during their private journeys. On about 50% of all flights, there is a doctor, emergency paramedic or firstattendant present on board by chance and, according to European law, they are obliged - even as passengers - to offer assistance. Conclusion: This lecture presents the initial results of training sessions, the experiences of physicians and paramedics, and reports on the lim and future possibilities for First Aid on board commercial aircraft. Name and address for correspondence: Dr. Joachim Huber, A-1020 Wien, Heinestrasse 36 Telephone No.:+43/664/3017966 Fax No.: +43/1/2166007 E-mail: j0achim.huber@doc-on-board.com Date: 30.06.2008 No 4. ABSTRACT ABSTRACT No 4. Title: LESS HYPOGLYCEMIC EVENTIS WITH EXENATIDE IN TYPE 2 DIABETES Author(s) Name: F. Strollo, M. Morè, M. Corigliano, G. Corigliano and G. Strollo, Introduction: One of the most threatening events in diabetic pilots is hypoglycemia, especially if abrupt and under unawareness conditions. Sometimes the fear for “hypo’s” puts AME’s into troubles and makes life less comfortable to patients too. In fact, pilots suffering from type 2 diabetes mellitus (T2DM) may even experience a progressive loss of self-confidence which may eventually lead to off-nominal attitudes, like taking less pills or eating more to try and keep always above the optimal glucose range and thus prevent hypoglycemia. A new drug, called exenatide, seems to ameliorate glucose metabolism while preventing hypoglycemic attacks. The aim of this study was to verify whether the rate of hypoglycemic episodes might be really reduced in diabetic subjects treated with the new drug. Methods: 30 men with T2DM switched from glibenclamide 7.5 mg + metformin 1200 mg per day to 10 mcg exenatide s.c. b.i.d. + lower daily doses of those two drugs for 3 months without changing their diet habits. Daily glucose profile, HbA1c and “hypo” events were recorded before and 3 months after the switch. Results: During the new treatment regimen, HbA1c, mean glucose levels and the rate of hypo’s decreased significantly (p<0,05). Conclusion: Exenatide seems safe enough in T2DM and may be adviced for pilots, who are engaged in a job potentially “dangerous” for their own and others’ lives. Name and address for correspondence: Felice Strollo, M.D. Prof., INRCA-IRCCS, Via Cassia 1167, 00189, Roma, Italy Telephone No.: +39.06.30342534 Fax No.: +39.06.30342534 E-mail: f.strollo@alice.it Date: June 28, 2008 ABSTRACT No 5. Title: Air Evacuation under Biosafety Containment of Patients with Highly Contagious Infectious Diseases Author(s) Name: M. Lastilla*, P. Tosco**, R. Biselli**, O. Sarlo** Introduction: Every year we have epidemics due to new-emerging or re-emerging highly contagious infectious diseases, such as SARS, Marburg fever, pandemic avian flu, etc. Global travel, military contingency operations in tropical environments and potential use of biological weapons by bioterrorists may place many people at risk for potentially lethal contagious diseases. In order to evacuate such kind of patients by military aircraft reducing to a minimum the risk for transmission to air crews, caregivers, and civilians, since 2005 the Health Department of Italian Air Force formed the “Aeromedical Isolation Team” (AIT). Methods: This is a rapid response team that can deploy to any area of the world, foreign or domestic, to transport and provide medical care under high containment to a limited number of patients exposed to, or infected with highly contagious, potentially lethal pathogens. For this duty, AIT includes two teams, each comprised of ten people (three physicians and seven nurses) and two Aircraft Transit Isolator (ATI) systems. This isolator completely separates the patient in a negative pressure envelope that protecting the accompanying medical team and the surrounding environment. Half suits and gloved sleeves incorporated in the envelope walls enable the attendants to examine and care for the patient. A battery powered air supply unit draws air through two inlet microbiological (HEPA) filters into the envelope and exhausts it through a similar filter at the foot end. Results: In January 2005 Italian Air Force AIT carried out its first transportation of a contagious patient using an isolator system. The patient suffered from multidrug resistant (MDR) Tuberculosis, an infectious disease transmitted by air way, more severe for the high resistance at medical treatment, and was transferred from Alghero Airport, in Sardinia Island, to Linate Airport, in Milan, by Lockheed C-130J aircraft. The flight lasted one hour in comparison with estimated twelve hours by ambulance and boat. The organization of Italian Air Force AIT is basically founded on the model of U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) AIT. In the second operative mission, in May of this year, Aeromedical Isolation Team was deployed to Turin for a patient suspected of having a Congo-Crimea fever, after returning from Nepal where a tick bite could be the reason of the disease. The patient was moved aboard a C130J from Turin to Spallanzani Hospital in Rome, in order to manage the patient in a BSL4 isolation facility and about the model of preparedness and response to highly contagious infectious diseases, in Italy Spallanzani Hospital at the present time is the golden choice (together Sacco Hospital in Milan). The patient died the day after, and the diagnosis of hemorrhagic fever was not confirmed by laboratory test, but probably the hemorrhagic syndrome was due to a fulminant epatitis by Herpes virus. The third deployment was three months ago, in July 2007, for a mission comparable to the first, this time for a Congo citizen, living in Italy, always with multidrug resistant tuberculosis, transferred from Sardinia to Bergamo, with destination the same Hospital near Milan specializing in tuberculosis Conclusion: At the present, Italian and US teams are using the same procedures, training and equipments, and this similar capability is a good starting point for a future collaboration in operational scenarios Name and address for correspondence: Major Marco Lastilla, ITAF Health Department, Viale P. Gobetti, 2A 00185 Rome, Italy Telephone No.: +390649865389 Fax No.: +390649864970 E-mail: marcolastilla@yahoo.it Date: 10 lug. 2008 ABSTRACT No 6. Title: Fainting Passengers: the Role of Cabin Environment Author(s) Name: Ries Simons, TNO Human Factors, Soesterberg, Netherlands Hans de Ree, KLM Health Services, Schiphol Airport, Netherlands Introduction: Reported percentages of in-flight medical incidents caused by syncope vary between 15% and 22%. Syncope is usually a benign medical event, but it may cause fear and distress among passengers and the individual involved. Incorrectly diagnosed benign syncope may lead to unnecessary flight diversions. In this context, the incidence of in-flight syncope and possible relationships with cabin environmental and passenger factors were studied. Methods: In September 2005 questionnaires were handed out to the senior purser on all KLM long haul flights. Pursers were asked to record all cases of in-flight syncope and to answer questions concerning cabin climate. Literature data were analyzed concerning in-flight and passenger factors that may cause or elicit syncope. Results: With a response rate of 79%, 1625 forms were analyzed. The in-flight syncope risk was 3-9 per 1000 passenger flight hours, depending on type of aircraft. The frequency of syncopal events was weakly correlated with cabin climate conditions. Literature analysis provides evidence that hypoxia is a sufficient cause for syncope in a sub-set of healthy airline passengers. There is evidence that cabin pressure and temperature may contribute to the occurrence of syncope. Conclusion: The syncope risk appears to be higher aboard an aircraft than on the ground. Hypoxia is a sufficient cause for syncope in a sub-set of healthy airline passengers. Airline passengers may become considerably hypoxic due to reduced pulmonary ventilation caused by immobility, drowsiness, and gastro-intestinal distension. In-flight hypoxia may reach levels sufficient to cause syncope. High cabin temperature may further trigger this reaction. Name and address for correspondence: Ries Simons MD, TNO Human Factors – P.O. Box 23, 3769 ZG Soesterberg, Netherlands Telephone No.:+31 346 356485 Fax No.: +31 346 354977 E-mail: ries.simons@tno.nl Date: 02-07-2008 ABSTRACT No 7. Title: The Aerotoxic Syndrome Author(s) Name: Professor Michael Bagshaw Introduction: There has been an increased number of reported incidents of in-flight smoke/fumes events since 1999, particularly in the UK, with a small number of crew members reporting adverse health effects which they associate with the events. There is wide interest in the UK media and at political level. However, the epidemiological evidence is hampered by inconsistency in reporting and the numbers are small. Methods: An empirical review of the prevalence and the reported symptoms and signs was conducted, together with consideration of the known toxicology of cabin air constituents. Results: There is wide disparity in reported symptoms and signs. Many of the symptoms and signs are consistent with other medical conditions and are known to be experienced on a daily basis by the normal population. A number of the tests employed to reach a diagnosis are lacking in objectivity and scientific validity. Conclusion: The evidence does not support the establishment of a new medical condition, the so-called aerotoxic syndrome. However, there is known to be genetic variability in individual sensitivity to chemical exposure and the aeromedical profession must remain vigilant. Name and address for correspondence: Prof M Bagshaw, 3 Bramley Grove, Crowthorne, Berkshire, RG45 6EB, UK Telephone No.: +44 7766 022158 Fax No.: +44 1344 775647 E-mail: mikebagshaw@doctors.org.uk Date: 19 August 2008 ABSTRACT No 8. Title: THE PERFORMANCE OF BLOOD PRESSURE MEASURING DEVICES AT GROUND LEVEL AND AT 8,000ft. Author(s) Name: M F Hudson, Medical Adviser Thomas Cook Airlines,: J Ernsting King’s College London Introduction: The blood pressure measuring device included in the majority of on board medical kits is an aneroid sphygmomanometer which requires a trained operator. Commercial Airlines are considering changing to an automatic sphygmomanometer that can be used by untrained personnel. The performance of a Littman aneroid sphygmomanometer and an Omron M5-I at ground level and an altitude of 8,000ft have been studied. Methods: Ten healthy volunteers aged between 21 and 63 were seated at rest breathing air in a hypobaric chamber and their blood pressures repeatedly determined using the aneroid and automatic devices together with orthodox Mercury sphygmomanometry. The measurements were made by four trained observers at ground level and at 8,000ft. Each of the three measurements on each subject at each altitude with the device were bracketed by four orthodox measurements. Results: The mean (+/-SD) systolic and diastolic pressures of the 10 subjects at ground level (orthodox method) were 115.7 +/- 7.5 and 75.6 +/-5.5 mm Hg. Compared with the orthodox values the mean systolic/diastolic pressures obtained using the aneroid device were +1.52/ -1.11 mm Hg at ground level and 1.72/ -0.04 mm Hg at 8,000ft. The changes in these differences between 0 and 8,000ft were not significant (P>0.2). The corresponding mean differences when using the automatic device were +5.74/ -2.89 mm Hg at ground level and 1.56/ +0.10 mm Hg at 8,000ft. The mean changes of 4.18/2.99 mm Hg with ascent were significant (P<0.05) Conclusion: Ascent to 8,000ft did not affect the accuracy of measurement of arterial pressure using an aneroid device as compared with orthodox sphygmomanometry. A small effect of altitude (3 – 4mm Hg) was found when using the automatic device, which is of little clinical significance for medical emergencies occurring in flight. The replacement in medical kits on aircraft of aneroid devices with an automatic device such as the Omron M5 I is justified and can be recommended. Real time measurements of the blood pressure taken by untrained personnel, such as cabin crew, can provide valuable information to ground based medical services which are currently used by most airlines in the management of medical emergencies in flight. Name and address for correspondence: Dr Martin F Hudson, MBBS, MRCP (UK), FRCP Edin, 7, Swanwick Close, Goostrey, CW4 8NU Cheshire, UK Telephone No.: +44 1477 532527 Fax No.: +44 1477 544059 E-mail: martin-hudson@lineone.net Date: July 14th 2008 ABSTRACT No 9. Title: Would you fly with this pilot after traumatic brain injury(TBI) Author(s) Name: A. MARTIN St LAURENT Introduction: TBI is a complex pathologic domain including mental and somatic injury. At the time of the trauma dissipation of energy is responsible for the cerebral lesions and the consequent neurological signs are dominated in loss of motor and cognitive functions and in modification of psychological and behavior. Among airmen the occurrence of TBI needs to adopt a physio -pathological approach and to evaluate the post trauma sequellae after a clinical, electrical and neuropsychological examination Methods: We report two cases of head trauma among pilots during a roller blade party. The AME analyses the initial lesions, taking into account GSC ( Glasgow Coma Scale), loss of consciousness, PTA ( Post Trauma Amnesia ) TDM lesions. So he may categorize the TBI and do the prognostication of the risk of PTE (Epilepsy). Complete neurological examination exploring psychological, cognitive and behavioral sphere is considered for a waiver to return to flying duties. Results: TBI with moderate or severe gravity should be restricted from flying for approximately 2 to 3 years to ensure that sequellae have disappeared. A request for waiver requires complete assessment. One case of TBI was accepted to return to fly after 3 y because of the loss of cortico -frontal substance, the risk of frontal syndrome and PTE. The other case was grounded after 3 y of follow-up because mild cerebellum deficit and cognitive defect at memory, attention and intellectual efficiency test. Conclusion: After TBI the AME has to consider the biomecanic phenomena that caused cerebral damage. Evaluation before flying again includes physical, neurological and cognitive expertise. But the risk of in-flight incapacitation by PTE must be assessed and the possibility of depressed mood evaluated by a psychiatrist. Name and address for correspondence: Dr A. MARTIN St LAURENT Alain Aeromedical Center Roissy Continental Square, 3 place de Londres BP 11201 95703 ROISSY-CDG Cedex Telephone No.:33(0)1 48 64 98 03 Fax No.: 33(0)1 48 64 17 43 E-mail:almartinsaintlaurent@airfrance.fr Date: 24 june 2008 ABSTRACT No 10. Title: Fundus Imaging improves efficacy and safety of medical exams Author(s) Name: Roland Quast / Helmut Wilhelm Introduction: Purpose of the study: Examination of the ocular fundus requires both skills and experience. For a non-ophthalmologist it is virtually impossible to evaluate the ocular fundus with undilated pupils. We employed a non mydriatic fundus camera and report our experience Methods: We reviewed 956 consecutive photographs of 478 pilots taken with the Nidek AFC-210 fundus camera equipped with a 12.8 megapixel digital camera body (Canon 5D). This camera allows photographs at an angle of view of 45 or 37° (adjustable), sufficient to image optic disc, macula and the major vessels Results: On 904 of 956 photographs (94.5%) optic disc, macula, vessels and inner 30° of the retina could be assessed complete, on 43 (4.5%) images only disc and vessels could be assessed, on 9 (1%) images the quality was too poor for assessment of the optic disc. Repetition of those 9 photographs with dilated pupil would have provided usable. The pathologic findings included markedly excavated optic disc (7), definite glaucoma, not yet diagnosed (1), macular changes (7), other pigment changes (3), optic disc drusen (2), choroidal naevus (1), myelinated nerve fibres (1) suspected choroidal osteoma (1), vitreous deposits (1). Conclusion: Even without pupil dilation fundus photography provided high quality results in 94%. Only 1% of the images could not be evaluated sufficiently. The number of pathologic findings was higher than expected according to our experience. Fundus photography can be done by a technician, takes usually less than 2 minutes per eye, does not require pupil dilation and has additionally the advantage of a reliable documentation. Suspicious findings can be evaluated “off line” by experts. Therefore this procedure increases both economy and quality of medical licensing Name and address for correspondence: Roland Quast Aeromedical Center Germany, OPS-Gebäude, 70629 Stuttgart-Airport Telephone No.:07117949466 Fax No.: 07117949467 E-mail: acg@flugmed.info Date: 30.07.2008 ABSTRACT No 11. Title: VISUAL OUTCOME AFTER CORNEAL REFRACTIVE SURGERY Author(s) Name: C.Stern, G. Kluge Introduction: The aim of pilots or applicants who undergo refractive surgery is in most cases a good visual acuity without visual aid. Therefore we were interested in the question of how many patients do meet the 1.0 visual acuity criteria after the surgery. We were also interested in the outcome of the near visual acuity after surgery because this is usually not paid any attention to by the surgeons. Methods: Refractive surgery leads to unfitness for flying after the European Requirements JAR-FCL 3. We identified all pilots and applicants who came to our Aeromedical Center to be reviewed to receive a waiver. Results: 76 professional, private pilots or applicants with 145 treated eyes came from July 2001 to September 2007 to our Aeromedical Center. The first refractive procedures were performed in 1988, the last in 2007. The highest treated myopia was -8.75 diopters, the highest treated hyperopia was +7.75diopters and the highest treated astigmatism was 6.5 diopters. From the 145 treated eyes 59 (40.7%) eyes did not meet the uncorrected distant visual acuity of 1.0. Of these 59 eyes 9 eyes were not correctable to 1.0 in the distance. In 30 eyes (20.7%) out of the 145 treated eyes the near visual acuity was not correctable to 1.0. Of these 30 eyes 25 eyes had a minimum visual acuity of 1.0 in the distance (corrected or uncorrected). Conclusion: 28 of the 76 patients need a correction to have normal visual acuity in the distance. That means in 37% of patients the aim for the refractive surgery was not met. A reduced corrected near visual acuity after refractive corneal surgery seems to go in most cases along with corneal haze or other complications. It seems to make sense to send pilots or applicants after refractive surgery with reduced best corrected visual acuity to an Ophthalmological examination. Name and address for correspondence: Dr. C. Stern; DLR; 51170 Köln, Germany Telephone No.: 0049-2203-601-3368 Fax No.: 0049-2203-601-4776 E-mail: Claudia.Stern@dlr.de Date: 24.07.2008 ABSTRACT No 12. No 12. ABSTRACT Title: Corneal refractive surgery among Hungarian pilots from 2001 to 2008 Author(s) Name:L.Ungváry MD Introduction: The purpose of this study was to describe the effect of corneal refractive surgery on fit for aviation.We examined 110 applicants underwent corneal refractive surgery from 2001 to 2008 . The complications and the results of the different surgical methods were analised. Methods:110 applicants were examined by the ophthalmologist . We use JAR FCL3 requirements for the examinations and certifications. Results: JAA Class1 (ATPL/CPL):17, Class 2 (PPL/steward):85, Class 3 (air traffic controller):8 subjects were examined after corneal refractive surgery in our Aeromedical Center in Budapest from 2001 to March 2008. The first refractive surgery was performed in 1992. The types of the corneal refractive surgeries are: PRK:92 LASIK:5 Intra LASIK:3 RK:8 LTK: 1.There was 1 therapic surgery for map-dot-spot corneal dystrophy. The highest treated myopia was -8,5 diopters and the highest treated hypermetropia was +6,0 diopters. No ophthalmologic complications have occurred. The best corrected visual acuity was 1,0 for far and for near. Conclusion: There were no serious complication among our patients. There are only 5 patients who have eyeglasses after the refractive surgery (4,7%). Based on our experiences the refractive surgery among the well-selected population do not has adverse effect on medical certification. We emphasise that all the pre- and postoperative examinations should perform by the ophthalmologist. Name and address for correspondence: Lilla Ungváry, Aeromedical Center Budapest 1097 Budapest Gyáli út 17.Hungary Telephone No.:+36-702203148 Fax No.: +36-13580975 E-mail: ulilla@freemail.hu Date: 01/07/2008 ABSTRACT No 13. Title: Mesopic Contrast Sensitivity in a Young Population Authors: Bente Haughom, Trond-Eirik Strand, Irene Berg Introduction: JAR-FCL requires that a candidate undergoing refractive surgery can be considered fit for flying provided that glare sensitivity is within “normal standards ” and mesopic contrast sensitivity is not “impaired ”. However, there is no standard examination for measuring glare sensitivity, and no comparable population norms for mesopic (low illumination) contrast sensitivity testing exists. Visual acuity measured by Snellens chart can be acceptable even in persons with a disabling glare disability. Methods: Mesopic contrast sensitivity, with and without glare, was measured as part of a standard ophthalmological examination. We used sine wave gratings/FACT (Functional Acuity Contrast Test) supplied by the Optec 6500, Vision Sciences Research Corp. Data was collected from routine examinations of current civilian and military pilots at the Norwegian Aeromedical Centre (AMC). Results: Data from the contrast sensitivity examinations of about 150 candidates, mostly males between 20-40 years, will be presented. Conclusion: There is a need for comparable population norms to evaluate mesopic contrast sensitivity. Refractive surgery has emphasized the need for objective parameters in the examination of pilot candidates after surgery, and our material will be used in this context. It can also be useful to evaluate side effects of refractive surgery, like night vision disturbances. Name and address for correspondence: Bente Haughom, Institute of Aviation Medicine Postboks 14 Blindern, NO-0313 Oslo, Norway Telephone No.: +47 92636391 Fax No.: E-mail: bente.haughom@medisin.uio.no Date: 26.06.08 ABSTRACT No 14. No 14. ABSTRACT Title: Aeromedical certification in progressive mitral valve prolapse. Author(s) Name: Elena Cataman, Aurel Batrinac Introduction: Mitral valve prolapse (MVP) is one of the most common heart valve abnormalities, affecting 5-10% of the general population. Pilots are not an exemption. The rate of MVP among pilots according to the data of different authors is 4,8% - 11%. The majority of affected are asymptomatic. As long as regurgitation is not significant, prognosis for aeromedical certification is favorable. Methods: We report a case of a 54-year-old ATPL pilot who was incidentally detected to have MVP at the age of 31 years at aeromedical examination for revalidation of medical certificate. He was asymptomatic with constant degree of mitral regurgitation and stable dimensions of cavities with normal stress ECG for a long period of time. From the moment when the left ventricular end diastolic dilatation of the heart (5,9 - 6,1 cm) and systolic dimension (4,0 – 4,1cm) became boundary to the normal for certification limits OML limitation was placed. The pilot was under continuous control and treatment of AME with biannual ECHO and ECG investigations, which made it possible for him to be issued with a medical certificate for a period of 8 years (2000 -2007). He was only considered unfit after the onset of atrial fibrillation. The surgical valve repair was recommended to pilot. 6 months after successful reconstruction of mitral valve with annuloplasty he returned to his duties.Results: Presentation shows the evolution of mitral valve prolapse in experienced pilot and the policy of aeromedical certification in different stages of the disease. Conclusion: Good medical monitoring and effective plastic surgery of MVP gives good prognosis for flight carrier. Rational approach to pilots with MVP should be taken in boundary conditions when acceptance for aeromedical certification is controversial. Name and address for correspondence: E. Cataman, Aeroport MD 2026, Chisinau, Moldova Telephone No.: + 373 22 52 64 36 Fax No.: + 373 22 52 91 18 E-mail: Cataman@caa.md Date: 30.07.2008 ABSTRACT No 15. Title: Overweight in Military Pilots and WSOs in Germany 1977-2006 Author(s) Name: GLASER, Hansjoerg Introduction: In Europe the prevalence of overweight and obesity is rising. Military pilots on the other hand are highly selected, continuously monitored, and health conscious. Therefore it remained unclear, to which extent they would be affected by this trend. Methods: Retrospective analysis of open cohorts of all military pilots and weapon systems officers re-assessed at the German Air Force Institute of Aviation Medicine with 47,273 data sets of height, weight, and age from 1977 to 2006 in 5-year age classes. Results: With only few exceptions there is a trend towards an increase of mean BMI in all age classes, starting around 1987. The proportions of aviators with overweight (BMI > 25) and more severe overweight (BMI > 27,5) are growing. Even obese (BMI > 30) aviators can be found in relevant numbers recently. Conclusion: The obesity epidemic has reached even the sub-population of military aviators, although in a milder form than in the general population. Name and address for correspondence: Dr. Hansjoerg Glaser, FlMedInstLw, Postfach 1264 / KFL, D – 82242 Fuerstenfeldbruck, Deutschland Telephone No.: +49 8141 5360 2200 Fax No.: +49 8141 5360 2166 E-mail: hansjoergglaser@bundeswehr.org Date: 23. July 2008 ABSTRACT No 16. Title: Framingham Coronary Risk Factors at Male Aviation Personnel – comparison with non Aviation Population in Slovak Republic. Author(s) Name: DAXNER Peter, Dr.Av.Med., PhD Introduction: The paper compares incidence of Coronary Heart Disease Risk Factors and its relative risk score at three group of male population – civil aviation personnel, military aviation personnel and non aviation population examined at 1997 and 2007 in Department of Aviation Medicine of Aviation Military Hospital in Kosice – Slovak Republic. Methods: The age, total cholesterol, HDL cholesterol, blood pressure, smoking and occurrence of diabetes were examined at 1817 male civil aviation personnel + male military aviation personnel and at 560 non aviation male subjects. Examination were performed during years 1997 and 2007. Coronary disease prediction algorithm developed at Framingham study was used for calculation of relative risk score for each examined subject. Group results were compared each other. Results: Relative risk score decreased in all groups since 1997 till 2007. The highest score was in military aviation personnel ( in 1997 and also in 2007). Lowest score was in non aviation group (in 1997 and also in 2007). Conclusion: The possible reasons of highest incidence and dependence of coronary disease risk factors at aviation population are discussed. Name and address for correspondence: Dr. Peter Daxner, PhD, Aviation Military Hospital, Murgas str. No 1, 040 86 Kosice, Slovak Republic Telephone No.: + 421 960 516 751 Fax No.: +421 960 516 765 E-mail: daxner@lvn.sk daxnerpet@mail.t-com.sk Date: 31.7.2008 ABSTRACT No 17. Title: Psychological diagnostics of foreign air staff in Air Military Hospital, Koice, Slovakia. Author(s) Name: Dr. MAYEROVA Juliana, Dr. SLOVENSKA Eva, Mgr. IMÁRIK Martin, PhD. Introduction: The paper mainly deals with psychological testing of board crew (air-hostess and stewardess) from India. They applied to work for one unnamed Slovak air company, which also operate air route from Slovakia to India. Candidates undergone completely medical inspection in our hospital and one part of that inspection were psychological diagnostics and testing. Methods: There were two inseparable parts of psychological procedure: first involve to tests administration (performance tests, personality questionnaires, projective methods), second involve to complex diagnostics interview. Results: From 22 applicants (19 women, 3 men) were 14 consider like eligible for accession (able for air staff position), 7 like able for air staff position, but less eligible, and finally, 1 (one) like unable. Summarily, there were a lot of intercultural differences (nature, behavior), and in compare with our population (Slovak, central Europe) they were seems like more slowly (especially in psychomotorical tempo). Conclusion: Diagnostics of foreigners (especially from different cultural and value conditions) may be great opportunity for intercultural comparisons and for new experience. There is a question if it´s good idea to employ the people from absolutely different cultural background and education in (for example) european conditions (in relate to trouble free and safety cooperation with other staff members and travellers also, of course). Name and address for correspondence: Mgr. Cizmarik Martin, PhD., psychologist, Aviation Military Hospital, Murgas str. No 1, 040 86, Kosice, Slovakia Telephone No.: +421 960 516 995 Fax No.: +421 960 516 765 E-mail: cizmarik@lvn.sk Date: 31.7.2008 ABSTRACT No 18. No 18. ABSTRACT Title: Neurocognitive Performance in Aircrew in treatment with antidepressant SSRIs and SNRIs. Author(s) Name: T.Col. CSArn Simeone IZZO* - Col. CSArn Prof. Gualberto ARDUINO** Br. Gen. CSArn Eugenio VELARDI*** - Prof. Stefano MOSTICONI **** (*), (**), (***) Italian Air Force –Aviation Medicine Institute - (****) University of Rome “La Sapienza” Introduction: Incidence of mood and anxiety disorders is getting higher in general population as well as in the aircrew community. For this kind of patients specific psychopharmacological treatments are not allowed by the currents rules for aviation medical licencing, because of the potential side effects on the neurological system (drowsiness, dizziness, lack of attention, etc…). On the other hand the symptoms linked to the mood and anxiety disorder, whereas not treated, might affect the individual global performance. The guidelines for the treatment of the mood and anxiety disorders are the early and long-term use of the antidepressant Selective Serotonin Reuptake Inhibithors (SSRIs) or Selective Noradrenergic Reuptake Inhibithors (SNRIs). Methods: Comparison of two group, control (242) and pathological (32) taking antidepressant on their performance at the: tachistoscope, tremor test, mental efficiency test, visual response test, two-hands coordination. Results: The only significant difference between the two groups is the shorter visual response time of the control group. There have not founded differences in the other parameters. Conclusion: The results show that the neurocognitive performance of subject taking antidepressant SSRIs or SNRIs are largely comparable with the control group. These findings confirm that their use is effective for the treatment of mood and anxiety disorders and suggest that, under a right specialistic monitoring, their use could be allowed even in the aircrew population when the clinical condition need it. Name and address for correspondence: T. Col. Simeone IZZO Telephone No.: +39-06 49865663 Fax No.: E-mail: izzos@libero.it Date: 12/09/2008 ABSTRACT No 19. Title: VESTBULAR ANALYZER AND DESORIENTATION IN SPACE OF MILITARY PILOTS Author(s) Name: M.Spahieva 1 1 , L. Aleksiev 2, A. Petkov 1, K. Kanev 1 Department of military medicine, 2 Centre of military medical expertise and aviation medicine , Military Medical Academy, Sofia, Bulgaria Introduction: Disorientation in space (DS) of the military pilot is one of the frequent causes for flight accidents provoked by human factor. Vestibular analyzer of the military pilot is adequately reconstructed in process of flight duty and training. Vestibular analyzer is increasing its resistance under the influence of the acceleration in three plane sin flight time. These high requirements towards vestibular analyzer (VA) are determined for high criteria concerning selection requirements for flight duty of candidates. For this reason the method for determining of Vestibular Vegetative Resistance (VVR) of the vestibular analyzer is maximal burden for semicircular canals and for Ottolit part of the vestibular analyzer as well. Goal of the research is investigation of the connection of vestibular analyzer, respectively its VVR and cases of space disorientation during flight time in air force pilots. Methods: This research is a result of anonymous data from questionnaires distributed amongst pilots of air force and medical documents of pilots who had an accident because of disorientation in space. Results: Vestibular analyzer of pilots has high resistance at time of investigation. Perfect and very good VVR have 70.40 % of the pilots participating in anonymous investigation and 73.90 % of them who have accidents during flight time. It was not observed correlation connection between VVR and disorientation in space: r < 0. 33. Conclusion: In author’s opinion appearance of disorientation in space is a result of disturbances in three basic components: visual, cognitive, and operative. High resistance of vestibular analyzer and mobilization of the will power permit getting out from critical situation and determine low percent of flight accidents because of disorientation in space. Keywords: VESTIBULAR ANALYZER, DESORIENTATION IN SPACE, MILITARY PILOTS Name and address for correspondence: M.Spahieva Telephone No. : (+ 359 2) 922 50 75 Fax No.: E-mail: dr_spahieva@abv.bg Date: 25.08.2008 ABSTRACT No 20. Title: THE ITALIAN AIR FORCE (ITAF) EXPERIENCE ON SPATIAL DISORIENTATION TRAINING. Author(s) Name: M. Lucertini, P. Trivelloni, O. Sarlo Introduction: Spatial Disorientation (SD) represents one of the major threats in flight safety, especially in military activities. In the period 1993-2001, SD was pointed out as a causal factor in more than 20% of ITAF class A flight mishaps and this induced the Inspectorate for Flight Safety to organize a dedicated program for SD prevention and recovery, which included aeromedical aspects. This part of the training was included within the global physiological training for ITAF aircrews. Thus, SD courses started in May 2002 and were specifically dedicated to those aircrews considered at higher risk for SD mishaps (i.e. fighter and helicopter pilots/navigators). The present study aims at analyzing the results obtained in this initial 6 year period of SD training. Methods: Globally 239 pilots and/or navigators from different ITAF squadrons attended a 2 day SD course, that included both theoretical and practical training sessions. They were distributed in 61 dedicated SD courses, calibrated for four trainees each. To evaluate the appreciation of the course on the part of the trainees, a questionnaire was administered at the end of the activities. The practical outcome of SD training in terms of flight safety was evaluated with an analysis of recent class A flight mishaps and of reports of in flight SD episodes. Results: The course resulted highly appreciated by most aircrews, with a percentage of 98% of extremely positive comments (also in anonymous formats). A steep increase in the number and percentage of in flight SD reports was observed from year 2004. In the period 2002-2007, two class A flight mishaps (out of a total of 15) were attributed to SD, corresponding to 13.3%. Such a percentage is 8.3% lower than in the period 1993-2001, when the program was not active yet. Conclusion: Although these data should be considered with caution, due to the short follow up period, a significant contribution for flight safety can be hypothesized on the part of ground based SD training. Name and address for correspondence: Col. Marco Lucertini, MD IML “Aldo di Loreto”, Via P. Gobetti 2, 00185 – Roma (Italy) Telephone No.: +390649866140 Fax No.: +390649866610 E-mail: marco.lucertini@aeronautica.difesa.it Date: 30/06/2006 ABSTRACT No 21. Title: Tinnitus and Hearing in a Norwegian Airline Pilot Population Authors: Anthony S. Wagstaff, Peter Blum Introduction: Noise is an important stressor in aviation work environments. Newer aircraft types do not necessarily have less cockpit noise than older designs. A Norwegian Airline experienced an increasing number of complaints with a possible relation to noise, including tinnitus and fatigue – and also a worry for long-term hearing damage. Some of the concerns were coupled with the phasing in of a new version of the Boeing 737 with a somewhat higher cockpit noise level. To investigate hearing related complaints and possible flightrelated causes, a combined audiometric/questionnaire study was devised. The hypothesis was that tinnitus or hearing damage might be more frequent with increasing flight hours if these symptoms are related to the working environment. Methods: All audiograms from pilots working in the airline were analysed and entered into a worksheet together with answers from at comprehensive questionnaire regarding hearing related complaints, noise and other personal and career data. After quality-control of data, the database was anonymised. Results: 39% of pilots answered the questionnaire. However, after comparative analysis of the “answer ” and “no-answer ” groups regarding age and hearing thresholds, the data were found to be representative regarding objective findings. 14% of those who answered the questionnaire (N=133) reported daily tinnitus. Hearing damage for at least one frequency (>20dB higher threshold than expected for the given age) with and without tinnitus was found in 10,5% and 12,8% respectively. No certain correlations with total flight hours or B737 flight hours in different versions were found for tinnitus or hearing threshold change. Outside work, only a history of impulse-types noise exposure had a significant correlation to hearing damage among those factors included in the questionnaire. Conclusions: No certain connection was found between tinnitus and hearing damage on the one side, and flight hours on the other. Impulse noise exposure outside work was found to be related to hearing damage. Tinnitus prevalence was not clearly different from other population-based tinnitus surveys although large differences between other studies mean that this conclusion must be treated with caution. Name and address for correspondence: Anthony S. Wagstaff, Institute of Aviation Medicine Postboks 14 Blindern, NO-0313 Oslo, Norway Telephone No.: +47 48010690 Fax No.: +47 22692037 E-mail: anthony.wagstaff@flymed.uio.no Date: 21.07.08 ABSTRACT No 22. EFFECTS OF HYPOXEMIC HYPOXIA ON PATTERN REVERSAL VISUAL EVOKED POTENTIALS (VEPs) Title: Dario Di Blasio 1, Giuseppe Ciniglio Appiani 1, Alessandro Carboni 2, Nicola Pescosolido 2 1 - It. Air Force Flight Test Center – Aerospace Medicine Department – Pratica di Mare AFB Rome 2 - “Sapienza” State University – Rome Authors: Introduction: Exposure to high altitude may lead to altered central nervous system functions, induced by Hypobaric Hypoxia. Sensory systems like Visual and Auditory systems are reported to be severely affected by Hypoxia. Hypobaric chambers are traditionally used in this kind of survey, but they carry a risk of inducing decompression sickness in trainees. An appropriate alternative is the use of low oxygen gas mixtures, in order to simulate breathing conditions at high altitude. Methods: The study was undertaken to assess the effects of Hypoxemic Hypoxia on pattern reversal Visual Evoked Potentials (VEPs) simulating a 18,000 feet altitude. VEPs can provide significant diagnostic information about the functional integrity of the visual system. Forty healthy military aircraft pilots, formerly experiencing Hypoxia at high altitude, breathed a sea level mixture of gases: 20.95% oxygen and 78.08% nitrogen. Subsequently, at simulated High Altitude (18,000 feet) subjects breathed a reduced oxygen gas mixture (10 % oxygen), inducing 70% of oxygen blood saturation, after approximately 5 - 8 minutes. Results: Latency increased both at 15’ (foveal) and 60’ (parafoveal) checkerboard pattern. Additionally, breathing a reduced oxygen gas mixture with 10 % oxygen, there was a decrease of P-100 wave amplitude in both eyes (at 15’ of arc more significant than at 60’). Conclusion: Exposure to simulated High Altitude (18,000 feet) may cause increase of roughly 1,2% latency delay of P-100 wave. The mentioned increase of P-100 latency peak times, along with the decrease of P-100 amplitude, at 15’ of arc checkerboard, may be due to synaptic delay and/or altered neuronal processing. Upcoming objectives: to assess pharmacological treatment expected to avoid altered sensory functions that reduce pilot’s performance and safety levels. LTC Dario Di Blasio, MD - Flight Test Center, Aerospace Medicine Dept. Pratica di Mare AFB 00040 Pomezia (RM) ITALY Telephone: +39-06-91292729 Fax: +39-06-91292075 E-mail: csv.rmas@tin.it Date: June 27th 2008 ABSTRACT No 23. Title: Medical requirements for Leisure Pilot Licence Author(s) Name: Virgilijus Valentukevicius, M.D., D.Av.Med Regulation 216/2008 requires the Agency to draft rules for a new leisure pilot licence (LPL). This licence will be sub-ICAO Class 2 standard and is created to provide easier access to general aviation. The medical requirements are less stringent than the former JAR-FCL 3 requirements for Class 2 and, if permitted under national law, the medical examination and assessment can be done by the family doctor of the pilot. LPL medical requirements are in line with limited flight privileges of licence holders. In this presentation the medical requirements for the leisure pilot licence will be outlined in some detail. Name and address for correspondence: Virgilijus Valentukevicius Telephone No: +49 221 89990 5045 Fax No.: +49 221 89990 5545 E-mail: virgilijus.valentukevicius@easa.europa.eu Date: 03/09/2008 ABSTRACT No 24. Title: Implementation of EU directive « Noise » into German law and consequences for flight crews Author(s) Name: Rose, D.-M., H.-J. Kimpflinger, Manuel Vierdt, J. Hedtmann Introduction: The EU directive “Noise on workplace” had been implemented into German law. Thus a reassessment of the noise burden of flight personnel had to be done, because the threshold value of noise for an 8 h day period was reduced from 85 db(A) to 80 db(A). If the threshold value exceeds 80 db(A) personnel has to be informed about possible health risks and personal hearing protection and preventive medical checkups have to be offered. Methods: Noise level measurements in a turboprop aircraft according to ISO standards were performed and the average noise exposure for an 8 h day was calculated for db(A). Results: Noise exposure in the cabin of the aircraft exceeded with 81 dB (A) the threshold value of 80 dB (A). Therefore the airline has to take actions in respect of the national law and EU guidelines. That potentially interferes with the quality of the on board service for passengers. Conclusion: Health protection of flight personnel is mandatory, but wearing of ear protection by flight attendants during on board service is not adequate. The exact analysis of noise levels during the different phases of the flight showed highest noise levels during the take-off period. Therefore, wearing individual hearing protection during take-off by cabin crews might change the total noise level below 80 dB (A) and could allow working during the rest time of flight without ear protection but without a health risk. However, further investigations are needed. Name and address for correspondence: Dr. Dirk-Matthias Rose, IAS Institute of Occupational und Community Medicine Foundation, Steinhäuserstr. 19, D-76135 Karlsruhe, Germany Telephone No.: (x49) (0)721 8204 111 Fax No.: (x49) (0)721 8204 440 E-mail: d.rose@ias-stiftung.de Date: 01th July 2008 ABSTRACT No 25. Title: Evaluating Whole body vibration levels in military and civilian helicopters according to levels defined by EC (2002/44/EC). Author(s) Name: Jan Ivar Kåsin, Anthony Wagstaff Introduction: Whole body vibration (WBV) is known to affect the muscular and skeletal system in the lower part of the spine. On the background of these effects The European Parliament and the Council of the European Union proposed a Directive in 2002 that stated the maximum levels of vibration exposure in a working environment. The action level was set to 0.5 m/s2 . The limit level was set to 1.15 m/s2 . In July 2005 the directive was implemented in the national labour inspection in every EU member countries. The national regulation makes the employers' responsible for examine possible WBV vulnerable work places. The Helicopter working environment is well known for substantial low frequency vibration. To be confident that different helicopter working environments were according to the regulation, we measured three military and three civilian helicopters. Methods: The following helicopters were measured: Bell412, Westland Sea King MK43B, Westland Sea Lynx MK86, Sikorsky S92, Eurocopter EC135 T2 and Eurocopter Super Puma L2. All operationally relevant manoeuvres were included in the test. The vibration levels were measured and recorded according to ISO 2631-1. Results: The Sikorsky S92 and Sea Lynx helicopter had the highest overall root-mean-square (RMS) acceleration values. EC135 T2 was the only helicopter with consistent levels below action value for all manoeuvres and altogether the helicopter with the overall lowest vibration levels. There are several possible reasons for the rather large differences between helicopters, with implications for possible health effects for helicopter aircrew. Some reservations regarding the results must be made based on individual airframe differences and helicopter configurations. Conclusion: None of the helicopters in passed the action level during an eight hour working day. We believe that the daily exposure level is lower in most of the helicopters since an eight hour flight time during a day is extraordinary. Name and address for correspondence: Institute of Aviation Medicine / Jan Ivar Kåsin – Sem Sælands vei 2B – 0313 Oslo Telephone No.: 22 93 03 40 Fax No.: E-mail: jik@flymed.no Date: 12.08.08 ABSTRACT No 26. Title: New regulations of EASA NPA 2008-17c, Practical ophthalmological aspects Author(s) Name: van Setten Gysbert Introduction: The current version of new rules according to NPA 2008-17c as published by today 220808 still has some disadvantage of heritage and several changes that makes an clinical ophthalmologist wonder and, possibly, concerned. Main focus of this presentations is posed on the recovery rate after cataract surgery and the rules given for visual stability after refractive surgery. Rules proposed will be compared to the clinical reality and possible consequences. Methods: The rules proposed as referred to above imply a being unfit for 3 month after cataract surgery. Earlier, a fit assignment may be considered according to 9.5 p 47 if recovery is complete. The current knowledge of ocular wound healing implies a visual recovery after cataract surgery in usually less than 6 weeks. A complete recovery, that is no further improvements or changes to be expected, may take longer. Results: It will be shown the recovery rate after cataract surgery could be shortened to approx 6 weeks. The visual stability of +/- 0.75 dpt / day after refractive surgery raises the issue if the pilot may be temporarily incapacitated without knowledge in flight. A contradiction to the visual requirements is possible. The text in the rules could gain significantly in practical transparency and applicability with minor revision. Discussion: No rule is perfect, but it may be expected to reflect the state of the art. Conclusion:. The concerns mentioned above, together with others, not mentioned here, have been brought to EASA’s attention. With this there might be hope for implementation resulting in a rulemaking a little step closer to the state of the art , making our skies safer and more pilot friendly. Name and address for correspondence: Gysbert van Setten, St Eriks Eye Hospital, Polhemsgatan 50, 112822 Stockholm, SWEDEN Telephone No.: 0046736504963 Fax No.: 004686723070 E-mail: avia33@aviation-ophthalmology.com Date: 220808 ABSTRACT No 27. Title: THE 'IRISH' VIEW ON THE NEW REGULATIONS FOR MEDICAL CERTIFICATION. WILL IT ALL CHANGE? Author(s) Name: Annetje. Roodenburg In the JAA states the medical certification of professional and private pilots is performed according to JAR-FCL-3. The system is well established now and would appear to be working. Pilots are being able to continue to undergo their medical examinations/assessments in their home state while flying on an Irish licence. At the request of their airline the majority of them needed to convert to an Irish licence. In a few years the system will have changed under EASA and we will all be certifying them according to the new ‘EASA-system’. How will this affect them and us? Will the system really change? Will the individual, industry and doctors, regulators and AaMEs be able to influence the rulemaking and if so how? As the Irish CMO, being responsible for the medical certification of many non national pilots, I will try and discuss the possibilities with you. I short overview of the legal basis will be given, followed by the rulemaking process and possibilities. Name and address for correspondence: Dr. Annetje Roodenburg , Aeromedical Section Hawkins Street, Dublin 2, Ireland, <annetje.roodenburg@iaa.ie> Telephone No.: +1-603 1512 Fax No.: +1 603 1400 E-mail: Date: ABSTRACT No 28. Title: Considerations concerning practical hypoxia training for commercial aircrew Author(s) Name: Ries Simons, M.D. The Accident Investigation Report concerning the Helios Airways Flight HCY 522 (14 August, 2005) recommends that “EASA/JAA require practical hypoxia training as a mandatory part of flight crew and cabin crew training. This training should include the use of recently developed hypoxia training tools that reduce the amount of oxygen a trainee receives while wearing a mask and performing tasks”. In this context, considerations are presented concerning usefulness, risks, and feasibility of practical hypoxia training of flight crew and cabin crew. Practical hypoxia training can be performed by exposure in a hypobaric chamber (hypobaric hypoxia), which has been the regular practice in Air Force personnel all over the world. Recently, a new technique has been advocated, using a Reduced-Oxygen-Breathing Device (ROBD) in a simulated flight environment. Advantages and disadvantages of hypobaric chamber training and ROBD hypoxia training will be discussed in terms of medical consequences, efficacy of training, and consequences for the aviation industry. Name and address for correspondence: Ries Simons, M.D., TNO Aerospace Medicine, P.O. Box 23, 3769 ZG Soesterberg, The Netherlands Telephone No.:+31 346 356485 Fax No.: +31 346 354799 E-mail: ries.simons@tno.nl Date: 23 August 2008 ABSTRACT No 29. Title: Cardiac arrest during hypobaric chamber exposure at a young pilot Author(s) Name: Mirela Anghel, M.D., Ph.D., Ilie Capanu, M.D., Marcela Muresan, M.D. Introduction: A case presentation of a sudden cardiac arrest during hypobaric exposure of a young subject Methods: A 28 years old supersonic pilot was exposed to hypobaric conditions during regular scheduled training. Personal and professional records, ECG and video recordings during exposure, as well as post-incident additional testing is presented. Results: Based on the clinical investigations, the conclusions regarding the aeromedical status of the pilot will be presented Conclusion: A typical case of a “Would you fly with this pilot?” decision in which a top pilot had to consider a career change due to physiological limitations. Name and address for correspondence: Ilie Capanu, National Institute of Aerospace Medicine, 88th M. Vulcanescu Street, Bucharest, Romania Telephone No.: +40213187247 Fax No.: E-mail: inmas2006@gmail.com Date: 23.06.2008 ABSTRACT No 30. No 30. ABSTRACT Title: Resistance assessment to hypobaric-hypoxic stress through simultaneous monitoring of the ECG recording and oxygen saturation Author(s) Name: Ilie Capanu, M.D., Dragos Vlad, M.D., Simona Berbecar, M.D., Ph.D. Introduction: The hypobaric hypoxia still remains a standard compulsory method for aeronautical personnel, due to its comprising character through resistance estimation, training and adaptive synergies of the tested subject. Methods: A number of 39 subjects ( 12 candidates, 17 pilots, and 10 fight instructors) were exposed to a simulated flight. Simultaneous ECG and oxygen saturation (SO2) readings were performed. ESR (erythrocyte sedimentation rate) were performed prior to exposure. Results: We analyzed correlations between ECG variations and SO2 as a marker of hypoxic resistance. Values and weaknesses of both are discussed. Furthermore, we evaluated the impact of ESR as a predictor of hypoxia resistance. For the pilots (27) group we found a 100% PPV and a 70% NPV and for candidates (12) a 100% PPV and a 75% NPV Conclusion: Monitoring of multiple parameters during hypoxia exposure leads to a better understanding of a candidate adaptation profile. Candidates with high ESR can be expected to have poor adaptation. Name and address for correspondence: Ilie Capanu, National Institute of Aerospace Medicine, 88th M. Vulcanescu Street, Bucharest, Romania Telephone No.: +40213187247 Fax No.: E-mail: inmas2006@gmail.com Date: 23.06.2008 ABSTRACT No 31. Title: Hypoxia awareness: the present and future of hypoxic training of Hungarian military aircrew Author(s) Name: S. Szabó1, A. Grósz2, Zs. Tótka1 Introduction: Practical pressure chamber and oral flight physiology trainings provide confirmed benefits for military flight personnel in recognizing their own responses to hypoxia. Although in the civilian area it was argued whether pressure chamber training was necessary at all and could be replaced by less hazardous exercises providing the same benefits for the pilots, in military aviation, even with the mask on, severe hypoxia can occur due to the faults or malfunctions of the oxygene system. From our point of view, the extensive indoctrination and recurrent training in pressure chambers is undoubtedly necessary to familiarize military aircrews with the individual symptoms of imminent hypoxia. Methods: Based on a real mishap in April, 2008, we made an attempt to overview what might have happened on board a MiG-29 performing a final approach and touch-and-go too low and late. We examined the possible role hypoxia and high Gs whether they could add errors to the pilot’s acts during the approach. After the accident we reconstructed the possible cockpit altitude profile in the pressure chamber. Results: By the help of a simple psychological test we clearly demonstrated the deterioration of cognitive functions during mild hypoxia. Graphically plotted against oxygen saturation we managed to point out the decrease in monotony tolerance and the increase in the number of errors. The aircraft did not have any malfunctions, thus we concluded that the cause of the mishap was the improper position of the mask. Conclusion: At certain subjects, previous high G-overloads, mild hypoxia and time constraint can lead to pilot errors in critical flight phases. Name and address for correspondence: Sándor András Szabó, M.D. Dr. Radó György Military Medical Centre, Institute of Aviation Medicine, Militar Fitness and Research 17, Balaton utca, Kecskemét 6000 HUNGARY Telephone No.: 00 36 76 581 600/ext. 3451 Fax No.: 00 36 76 581 600/ext. 3466 E-mail: sasi1962@hotmail.com Date: 8th September, 2008 ABSTRACT No 32. Title: (POSTER) ASSESSMENT OF PUSH-PULL EFFECTS: A NEW PROCEDURE BASED ON A TEXTILE WEARABLE SYSTEM FOR VITAL SIGNS RECORDING. Author(s) Name: Anton Giulio Guadagno, MD*; Salvatore Cacopardo, MD*; Pierandrea Trivelloni MD*; Francesco Rizzo **; Paolo Meriggi PhD**; Marco Di Rienzo, MSc.** *Italian Air Force - Flight Test Center Aerospace Medicine Department, Pratica di Mare Air Force Base, 00040 Pomezia (Rome). ** Polo Tecnologico, Fondazione Don Carlo Gnocchi ONLUS, Milano. Introduction: The Push-Pull Effect (PPE) is a physiological phenomenon defined as a reduction of +Gz tolerance induced by a previous exposure to a –Gz. This phenomenon is considered a potential cause of G-LOC. Objective of this study was the definition of a new procedure for the assessment of heart rate effects induced by PPE during real military flights. Methods: The developed procedure is based on the recording of ECG, respiratory rate and 3D accelerations during flight maneuvres resulting in three different level of gravitational stress: -1Gz/+3 Gz, -1G/+4 Gz, and -1G/+5G. In each flight, lasting about 60 minutes, these manoeuvres were repeated by using different G onsets. Biological signals and accelerations were recorded by using a new textile system for the unobtrusive assessment of vital signs. This device, named MagIC, was recently developed by the Polo Tecnologico of Don Carlo Gnocchi Onlus Foundation, and is composed of a vest embedding textile-based sensors, and a miniaturized electronic module which stores data locally on a memory card. The new procedure was tested on two subjects during real flights. Results: From the analysis of the data we observed that: 1) the flight protocol can be easily implemented by the pilots, 2) the quality of the signals collected by MagIC is suitable for the subsequent elaborations, 3) the textile vest did not limit the pilots comfort nor interfered with their movements during flight maneuvres. Conclusion: The positive results we obtained, encourage the use of the procedure as a tool for the evaluation of PPE in real flight conditions and for the evaluation of the efficacy of possible countermeasure actions or devices. Name and address for correspondence: Italian Air Force - Flight Test Center Aerospace Medicine Department, Pratica di Mare Air Force Base, 00040 Pomezia (Rome). Telephone No.: +390691292296 Fax No.: +390691292075 E-mail: csv.rmas@tin.it Date: ABSTRACT No 33. Title: Injury- and fatality-rates in German general aviation accidents – a five year review Author(s) Name: Neuhaus C1 , Dambier M 1 , Glaser E1 , Hinkelbein J 1 , 2 , Pongratz H1 1 German Society of Aerospace Medicine(DGLRM), Workgroup Aviation Medicine University Clinic for Anesthesiology and Intensive Care Medicine, Medical Faculty Mannheim, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany Objective: Analysis of accident statistics, with special regard to injury and fatality rates, has great importance to improve safety. Fairly accurate risk assessment is possible, since there is detailed data available on hours and miles flown as well as the total number of passengers transported. Unfortunately, no such data is available for general aviation (GA). The German Federal Bureau of Aircraft Accidents Investigation (Bundesstelle für Flugunfalluntersuchungen, BFU), however, publishes detailed raw data (i.e. numbers) on german GA accidents, including injury and fatality counts (but no information about POB). The aim of this study was to evaluate probabilities for severe and/or fatal injuries sustained in german GA aircraft accidents. Material and methods: Using official data from the 2002 – 2006 BFU annual reports [1], the total number of GA accidents, number of GA accidents with severe or fatal injuries as well as the number of severely or fatally injured persons was obtained for a five year period. Data was assigned to subgroups (according to the aircraft category) for detailed analysis, including aircraft with MTOW < 2,0 to., aircraft with MTOW between 2,0 – 5,7 to., helicopters, TMGs, gliders and hot air balloons. Analysis focused on the average number of injured (ANI) and average number of killed (ANK) persons in accidents involving severe or fatal injuries, and the probabilies of sustaining severe (POS) or fatal (POF) or both (POS/F) injuries in a GA accident. Data was corrected for double counts (accidents with both severe and fatal injuries). Results: There were a total of 1394 accidents involving GA aircraft in Germany, including 215 with severe and 179 with fatal injuries sustained, resulting in 301 injured and 279 killed persons. Looking at accidents resulting in severe injuries, the highest ANI per accident was found in the MTOW 2.0 – 5.7to. category (4.0), albeit with the lowest overall probability of 4.88% (meaning that 1 in 20.5 accidents in this category leads to serious injuries). In contrast, the ANI in hot air balloon accidents is 1.3 with a highest overall probability of 77.91% (1 in 1.28). The lowest ANI was found in glider accidents (ANI=1.12, POS=15.49%; ANK=1.06, POF=12.69%). The ANK was also highest in the MTOW 2.0 – 5.7to. category (3.43) with a probability of 17.07% (1 in 5.86), but lowest in hot air balloon accidents (ANK=0, POF=0.00%), where no fatal accidents were recorded during 2002 – 2006. The POF was highest in helicopter accidents (20.00%) with an ANK of 1.67. Aircraft with MTOW < 2.0 to. (ANI=1.88, POS=7.48%; ANK=1.81, POF=15.14%) and TMGs (ANI=1.45, POS=8.09%; ANK=1.45, POF=8.09%) are somewhere in between. The POS/F was highest in hot air balloons (77.91%) followed by helicopters (30.00%), gliders (26.87%), Aircraft with MTOW < 2.0 to. (20.00%), Aircraft with MTOW 2.0 – 5.7 to. (19.51%) and lowest in TMGs (15.44%). Conclusion: Understandably, the ANI and ANK in GA accidents increase with airplane size and capacity. However, underlying reasons for the higher probabilities for injury and death in smaller airplane accidents remain unclear (lower safety standards, training, proficiency?) and necessitate further investigation. Especially for hot air balloons, new approaches for increased passenger safety should be explored. References: [1] http://www.bfu-web.de 2 Name and address for correspondence: Christopher Neuhaus – Bergstrasse 97 – D-69121 Heidelberg Telephone No.: +49-170-9079460 Fax No.: E-mail: chneuhaus@web.de Date: 25.08.2008 ABSTRACT No 34. No 34. ABSTRACT Title: Advanced Coronary Diagnostics: Multi-Detector Computer Tomography (MDCT) to diagnose Coronary Heart Disease (CHD) in military pilots Author(s) Name: Wonhas C, Hausleiter J, Ledderhos C, Martinoff S, Schömig A Introduction: Early detection of coronary artery disease (CAD) is of capital interest, when as ymptomatic candidates are certified for military flying duties, especially, as 40% of patients die with the first symptoms. 50% of them have a coronary risk score below 5 % per 10 years and a degree of coronary stenosis < 50%. Besides invasive coronary angiography (ICA) as standard for the exclusion of obstructive CAD, cardiac computertomographic angiography (CCTA) is able to exclude CAD. Studies demonstrated a high negative predictive value of CCTA (>95%), compared with ICA. Methods: Between June 2003 and September 2006 bicycle stress tests of 6910 subjects, routinely performed at the German Airforce Institute of Aviation Medicine (GAFIAM), were checked for higher degree ventricular rhythm disturbances (Lown class IIIb and higher) or new ST-segment depressions (including non-significant changes). CCTA was performed in subjects with positive bicycle stress tests. The presence of CAD was defined as coronary angiosclerosis. ICA was recommended in airmen with lumen narrowing > 50% in any major coronary branch. Results: In 1.6% (110/6910) asymptomatic airmen CCTA was performed without complications. In 29.1% (32/110) of them CAD was detected and excluded in 70.9% (78/110). In 19 subjects ICA was performed subsequently, leading to 8 drug eluting stent implantations and 1 coronary bypass grafting. A strict prevention strategy was recommended. In 32% (6/19) extensive coronary calcifications were present by CCTA. Two of 32 (6%) subjects with stenosis > 30% had a zero-calcium score. There were no false positive CAD results by CCTA. No cardiovascular events were observed in the 78 airmen with exclusion of CAD by CCTA within the follow-up period. Conclusion: Non-invasive CCTA is an attractive diagnostic method to rule out obstructive CAD in asymptomatic airmen certified for military flying duties. The method is safe as well as accurate and may help to reduce the number of ICAs, performed for diagnostic purposes only. Name and address for correspondence: Dr. Ch. Wonhas LtCol MC, FS, German Air Force Institute of Aviation Medicine (GAFIAM), Strasse der Luftwaffe, 82242 Fuerstenfeldbruck, Germany Telephone No.:0049-8141-5360-2033 Fax No.: 0049-8141-5360-2989 E-mail: christophwonhas@bundeswehr.org Date: 12.08.08 ABSTRACT No 35. DEVELOPING A METHOD FOR THE QUANTITATIVE ASSESSMENT OF GMEASLES C. LEDDERHOS*, B. DEBRABANT#, K. DEBRABANT#, R. MÖRLIN* and A. GENS* * German Air Force Institute for Aviation Medicine, Fuerstenfeldbruck and Koenigsbrueck, Germany, Darmstadt Technical University, Mathematics Department, Germany Introduction: Until now, no standardized diagnostic method for quantitative assessment of G-Measles following exposure to G-loads exists in aviation medicine. Objectives: Therefore an attempt was made to develop such a method as part of a comparative study on two different anti-G suits (AEA BAeS and Libelle G-Multiplus®). Methods: For this, the subjects were exposed to eight standard profile runs over a total of three days. Examination of subjects for the presence and the degree of severity of GMeasles was done by one and the same physician at the end of each day. The size of the affected area and the degree of severity were documented on a datasheet showing the front and the reverse of a standardized human silhouette. For the degree of severity of the GMeasles a three-level assessment scale (low, medium, severe) was used. Additionally a photographic documentation served the verification of exact evaluation of affected areas on the datasheet. Subsequently, all datasheets were digitized, the marked regions measured (separately for each degree of severity) and their percentage with respect to the entire surface was calculated. All data of the database were statistically evaluated for affected areas, side of body and degree of severity. Conclusions: Overall, this „method for the quantitative assessment of G-Measles “ allowed for the sufficiently accurate and reproducible quantification of the incidence of GMeasles in terms of the area of the affected region and of the corresponding severity using a subjective scale. Tangible measurements exemplarily shown on the poster will demonstrate this. Name and address for correspondence: Dr. Carla Ledderhos Telephone No.: +49 8141 5360 2145 Fax No.: +49 8141 5360 2999 E-mail: carlaledderhos@bundeswehr.org Date: 04.09.08 ABSTRACT No 36. Title: Comparison of Studies on General Aviation Accidents in different Countries using the HFACS Model Author(s) Name: Hinkelbein J1,2, Dambier M2, Glaser E2, Neuhaus C2, Pongratz H2 1 University Hospital Mannheim, Medical Faculty Mannheim of Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany 2 German Aerospace Society (DGLRM) Introduction: Analyzing aircraft accidents may improve flight safety. The application of the HFACS model [1] for aircraft accident analysis facilitates comparisons between different studies and countries. The aim of the present study was to compare published studies on aircraft accidents in the field of General Aviation (GA) and to identify and compare causing factors by means of the HFACS model. Methods: A systematic Medline research was performed to gather all published studies on GA aircraft accidents between 1968 and 2007. Data was compared using the HFACS model. Results: A total of N=10 studies on GA accident analysis were identified. N=6 studies were excluded from analysis due to their subject of investigation which was mainly military and airline operation. N=4 studies dated 1978 to 2005 were analyzed [2-5]. The mean time frame of these studies was 11±9 years. Three studies analyzed US and one German GA accidents. A total of N=534 aircraft accidents was analyzed in these four studies. None of the studies reported ergonomical or medical problems causing these accidents. Only one study reports 7 % of accidents due to crew resource management problems and 15 % due to organizational factors. All four studies state skill-based errors as the main reason (mean 53±19 %) for accidents. Decision errors (21 % and 37 %) were reported in only two studies. Only one study mentions perception errors (34 %) and violations (8 %) as causing factors. Pilot errors were reported to contribute to GA accidents homogenously in approx. 80 % of all analyzed cases. Conclusion: Comparing different published studies on GA accidents is difficult due to inhomogeneous denominator data. For future research it is essential to define uniform denominator data and consistent data sets. Skill-based pilot errors were homogenously reported as the main causing factors, but were not further divided and analyzed. References: [1] Shappell SA et al. Human Factors and Aerospace Safety 2001;1:5986. [2] Dambier M et al. Air Med J 2006; 25(6):265-269. [3] Pagan BJ et al. Aviat Space Environ Med 2006;77(9):950-952. [4] van Doorn RRA et al. Aviat Space Environ Med 2007;78(1):26-28. [5] Gaur D. Aviat Space Environ Med 2005;76(5):501-505. Name and address for correspondence: Dr. med. Jochen Hinkelbein, Neckarpromenade 16, 68167 Mannheim, Germany Telephone No.: +49.621.383.3798 Fax No.: +49.621.383.732740 E-mail: jochen.hinkelbein@gmx.de Date: 26.08.2008 ABSTRACT No 37. Title: A simple technique for gravity simulation (+1Gz, 0Gz, and -1Gz) demonstrates compromised lung function Author(s) Name: Neuhaus C 1, Dambier M 1, Glaser E1,2, Hinkelbein J 1,3, Pongratz H1 1 German Society of Aerospace Medicine(DGLRM), Workgroup Aviation Medicine Viasys Healthcare GmbH, Hoechberg, Germany 3 University Clinic for Anesthesiology and Intensive Care Medicine, Medical Faculty Mannheim, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany 2 Objective: During flight, gravity and acceleration can impose physical stress on the human body [1,2]. While military pilots are both medically evaluated and routinely trained for G tolerance using centrifuges, there is no such option for the civilian AME. However, severe acceleration and gravity changes do also occur in General Aviation (GA), e.g. during acrobatic flight. The aim of this pilot study was to analyze changes in basic lung function under the influence of gravity using a simple technique for gravity simulation. Material and Methods: After informed consent, 10 healthy pilots with a current flight medical certificate (at least class 2) were investigated. Gravity simulation was performed using a previously described technique [3]. Spirometry was performed in upright standing position (simulation of +1Gz for 2 minutes, 2 values each), in lying position (0G z, 2 min, 2 values), and head down position (-1Gz, 2min, 2 values) using a portable spirometer (SpiroPro, Viasys Healthcare GmbH, Hoechberg, Germany). Lung function changes were calculated for common spirometry test values (FVC, FEV1, FEV1%, PEF). Wilcoxon- and Mann-Whitney-U tests were used for statistical analysis of data, a P<0.05 was considered significant. Results: Ten healthy pilots (male, 32±7 years old, BMI 23.7±1.3 kg m-) were investigated. Change from simulated +1G z to simulated 0Gz showed no difference (FVC 5.53±0.28 vs 5.43±0.26, P=0.57; FEV1 4.71±0.33 vs 4.50±0.27, P=0.08; FEV1% 99.05±5.07 vs 94.65±5.55, P=0.11; PEF 11.79±0.90 vs 12.47±1.89, P=0.62). With simulated -1G z in head down position, change of FVC (5.53±0.28 vs 5.40±0.29, P=0.43) and FEV1 (4.71±0.33 vs 4.51±0.39, P=0.11) remained unsignificant. However, FEV1% decreased significantly from 99.05±5.07 to 94.20±6.02 (P=0.033) and PEF dropped significantly from 11.79±0.90 to 10.44±0.49 (+1Gz vs. -1G z, P<0.001). Conclusion: These findings under only minor Gz loading suggest that lung function is significantly impaired with increasing (negative) Gz load. Although a simple technique for gravity simulation was used, results are in concordance with current flight literature [4]. Especially for pilots that hold less restrictive Class 2 medicals but suffer from existing (deemed non-hazardous) lung conditions, the G forces possibly encountered in recreational aviation (recovery situations, amateur aerobatics) could be potentially harmful. Also, with centrifuges not usually available for medical evaluations, further investigation of screening methods for AMEs (such as the described technique or a tilting table) may be recommendable to provide simple tools for advanced risk assessment. Furthermore, G onset rates and integral load need to be considered as parameters for further investigations. Name and address for correspondence: Christopher Neuhaus, Bergstrasse 97, 69121 D-Heidelberg Telephone No.: +49-170-9079460 Fax No.: E-mail: chneuhaus@web.de Date: 25.8.2008 ABSTRACT No 38. No 38. ABSTRACT POSSIBILITIES FOR THE DETECTION OF IN-FLIGHT HYPOXIA – PULSE OXIMETRY C. LEDDERHOS, C1. A. GENS1 G. RALL2 ; 1 German Air Force Institute for Aviation Medicine, Fuerstenfeldbruck,, 2 Fraunhofer Patent Center for German Research, Munich Introduction: Pilots are exposed to different burdens during high altitude flights. Among others the reduction of PO2 is of special importance since the resulting effects of lack of oxygen often occur fast and unexpected. The symptoms accompanied by this appear to be very different not only interindividually but also intra-individually. Moreover they are often not identically reproducible by consecutive simulations of oxygen deficiency situations. Of particular danger is the possibility of an europhoric action of the hypoxia accompanied by the absence of the ability for self-criticism. Under those circumstances the early detection of hypoxia in pilots is of increasing importance. First practical attempts to do this are going back to World War II. At that time oximeters were used. In 1972 Takuo Aoyagi developed pulsoximetry; first commercially availabe units were available since the early 80s. Since than the measurement of oxygen saturation of the blood by pulse oximetry has become an objective, reliable and noninvasive method, even under adverse conditions. However devices originally developed for a clinical setting have some limitations which restrict their application in aviation and other operational conditions. Bright light as well as vibrations, accelerations and movement artifacts, as they regularly occur in aviation, can limit their usefulness dramatically. And although pulsoximetry is used frequently for demonstration and training purposes in the Air Force, this technique could not gain acceptance during real flight missions - until now. Objectives: As a consequence of the mentioned shortcomings it therefore appeared appropriate to validate an accepted clinical method under in-flight conditions, since it would enable for a simple monitoring of the central key spot of danger, namely an undue drop in blood oxygen saturation to a value, critical for health and flight safety. Methods and results: For flight purposes we decided to use reflectance sensors, which can be used at the forehead, with a low in-flight encumbrance of the pilot. However such reflectance sensors are known to be prone to motion artifacts and vibrations. In a first study at a hypobaric chamber we could show, that a sensor (NONIN company) working by the reflectance principle is generally suitable as an early warning system for an arterial oxygen deficiency. The only disadvantage – compared to the gold standard, the bloody measurement of oxygen saturation - were slightly higher oxygen saturation readings. Following studies of our group, mainly concentrating on the influence of vibrations and movements typical for helicopters on the signal quality, could demonstrate that this type of sensor generated a sufficient quality of signals in both simulated and real-world helicopter operations. During physical loads such as running, bicycling and skating the failure rate was 3 - 4 % only. Even runs in a human-use centrifuge up to 9 Gz still produced a good quality of signals. Conclusions: Regarding the application of a reflectance pulse oximeter sensor under operational real-flight conditions these results are very promising. The sensor appears to be perfectly suitable to warn of sudden and unexpected in-flight oxygen deficiency events. Name and address for correspondence: Dr. Carla Ledderhos Telephone No.: +49 8141 5360 2145 Fax No.: +49 8141 5360 2999 E-mail: carlaledderhos@bundeswehr.org Date: 04.09.08 ABSTRACT No 39. Title: Measuring psychic stress with biological data Author(s) Name: A. Grósz1, E. Tóth2, Á. Szatmári2 Introduction: Although nowadays the growing performance of computers largely facilitates the work of humans controlling aerial man-machine systems and many aircraft subsystems are becoming more automated, it is still the human being who makes decisions and controls that system. Therefore only those applicants should be selected for this occupation who can perform these tasks without particular mental efforts. In our experiment we attempted to verify our hypothesis according to which heart period variability (HPV) can be used as an appropriate index in the assessment of psychic load and its bearing in case of future pilot applicants. Methods: For this purpose we used a visuomotor coordination test to measure 28 male subject’s accuracy, speed and level of coordination in space and time. At the same time we equipped the subjects with an on-board data recording system (ECG, galvanic skin resistance, body temperature, pulse and breath rate) which provided precise measurements of the subjects’ HPVs. After a 3-minute initial resting period, the subjects familiarized themselves with the controls and then practiced the task. After this they carried out the task and finally had a 3-minute resting period again during which they filled in workload questionnaires. Results: Each subject accomplished the task successfully. After the analysis we used a conventional coordinate system with axes of speed and accuracy to display the results. We needed those subjects whose results were in the field surrounded by the positive part of the mentioned axes (fast and accurate). The subjects’ resting HPV values were also compared to their workload values. During heavier workloads the heart periods became shorter (sympathetic reaction), while during resting they became longer (parasympathetic reaction). We highlighted the subjects from among those selected previously whose HPV remained low, i.e. who stayed calm during task accomplishment. Conclusion: From the aspect of the pilot applicants’ medical selection, it is possible to select the persons who performed the „easy and reassurring ” task quickly and accurately with no particular mental efforts by two objective tests and a set of subjective responses. Name and address for correspondence: (1) Prof. Andor Grósz, M.D. Dept. of Aviation and Space Medicine, Faculty of Medicine, University of Szeged 17, Balaton utca, Kecskemét 6000 HUNGARY Telephone No.: 00 36 76 481 254 Fax No.: 00 36 76 481 254, 00 36 76481 659 E-mail: grosza@aeromed.hu Date: 4th September, 2008 ABSTRACT No 40. Title: Signal detection in hypobaric hypoxia - a stress situation Author(s) Name: A. Grósz1, E. Tóth2, Á. Szatmári2 Introduction: On the ground and in the air the actions of aircraft pilots are fundamentally influenced by their visual environment and the certain stimuli extracted from it. These stimuli often require quick decisions and acts, however, the time for these is considerably limited. Pilots can as well be and are exposed to hypobaric hypoxia during their flights which, according to our hypothesis, has a deteriorating effect on their signal detection performance. Methods: By the help of a darkened pressure chamber we used to model a stress environment with, we attempted to follow and assess the visuomotor performance of 42 healthy male helicopter pilots at a simulated altitude of 5500 m. During the signal detection test applied in this experiment the subjects had to recognize certain patterns (squares) of white dots randomly appearing on the otherwise black monitor display. In the first experiment 14 subjects performed the test at an altutide of 0 m, while other 14 performed it in the pressure chamber at 5500 m. In the second experiment 14 subjects performed the test at 0m, and then at 5500 m. During the tests we measured the number of correct reactions, detection time, the number of not-detected crucial stimuli and the number of incorrect reactions. The test computer also divided the screen into 4 quadrants and measured the previous criteria in each of them and on the whole screen as well. Results: Neither exhaustion nor learning effects were observed in any of the groups, however, the subjects remained motivated enough. The subjects’ oxygen saturation was around 70 per cent. After analysis we found that hypoxia did not influence the subjects’ initial and overall performance at all; however, they did not scan the screen evenly: the majority of the pilots preferred the top left quadrant and neglected the bottom right one. Conclusion: The explanation for this was that in the helicopter they fly (Mi-8, Mi-17) the most important flight instruments frequently checked by the pilots are located in the top left quadrant of the instrument panel, while the bottom right one contains gauges that are of low importance from the aspect of flight safety. This seemingly pathological result was the effect of a profession-based habituation and not that of deteriorated mental or visual performance caused by hypoxia. Name and address for correspondence: (1) Prof. Andor Grósz, M.D. Dept. of Aviation and Space Medicine, Faculty of Medicine, University of Szeged .17, Balaton utca, Kecskemét 6000 HUNGARY Telephone No.: 00 36 76 481 254 Fax No.: 00 36 76 481 254, 00 36 76 481 659 E-mail: grosza@aeromed.hu Date: 4th September, 2008 ABSTRACT No 41. Title: Markov State Transition Models for the Prediction of Changes in Sleep Structure Induced by Aircraft Noise Author(s) Name: Mathias Basner*, Uwe Siebert** *German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany, ** UMIT, Department of Public Health, Medical Decision Making and Health Technology Assessment, Hall in Tirol, Austria OBJECTIVES: To quantitatively assess the effects of the introduction of a nocturnal air traffic curfew at Frankfurt Airport on sleep structure. Methods: A six state (Wake, S1, S2, S3, S4 and REM) Markov state transition sleep model was built. Transition probabilities between states were calculated with autoregressive multinomial logistic regression based on polysomnographic laboratory study data. Monte Carlo simulation trials were performed for modelling a noise-free night and three noise scenarios: (1) traffic at Frankfurt Airport on 16 August 2005, (2) as (1), but flights between 11 pm and 5 am cancelled and (3) as (2), with flights between 11 pm and 5 am from (1) rescheduled to periods before 11 pm and after 5 am. Results: The results indicate that there will be a small benefit for airport residents compared to the current situation even if all traffic is rescheduled (average time spent awake -3.2%, S1 -4.6%, S2 -0.9%, S3 +3%, S4 +9.2%, REM +0.6%, number of sleep stage changes -2.5%). This benefit is likely to be outweighed by the increase in air traffic during shoulder hours, especially for those who choose to or have to go to bed before 10:30 pm or after 1 am. Conclusion: Alternative strategies might be necessary to both guarantee undisturbed sleep of airport residents and to minimize economic and legal disadvantages accompanied by a traffic curfew. The models developed in this investigation may serve as a valuable tool for optimizing air traffic patterns at airports, and therefore guide political decision making. Name and address for correspondence: Mathias Basner, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany Telephone No.: Fax No.: E-mail: mathias.basner@dlr.de Date: August 2008 ABSTRACT No 42. No 42. ABSTRACT Title: The problem of a“Human factor” under extreme aviation conditions Author(s) Name: candidate of psychological sciences Sitara Tariyel Mammadova Introduction: presented is devoted to the problem of a “human factor” aviation emergency, and studies the psycophysiological training of the flight operations and traffic control personnel, their errors actions in extreme (emergency) situations. The studies revealed that aviation events directly depend on pilots actions: particularly, on their psycophysiological state, as well as on their individual psychological features, especially on their sensor-motor reaction and on their intellectual and spatial abilities. Methods: modern psychological tests at comp . and analiz mathematical and statistical processing of psychological results Results: of psycophysiological analysis of the rich empirical data reveals psycophysiological, social and psychological, as well as individual and psychological factors influencing the behavior (actions) of the flight operations and traffic control personnel. Along with it, the dissertation presents psycophysiological filatures and psychological training of the flight operations and traffic control personnel. The mathematical and statistical processing of obtained psychological results of psycodiagnostic pilots tests has been carried out. Conclusion: The results of studies carried out have been summarized and presented in Conclusion. The work presented is of great scientific and theoretical as well as practical significance. Its data and findings (conclusions) can be successfully used (applied) in developing ways and manners for studying error actions of flight operations personnel (flying personnel). Name and address for correspondence: Azerbaycan, Baku, Ahmedli, M.Rustamov22,flat 23 Telephone No.:99450-361-27-00 Fax No.: 99412-456-25-93 E-mail: sitara_m@mail.ru Date: 10.09.2008 ABSTRACT No 43. Title: PRECANCEROUS SIGNS IN THE MOUTH DETECTED DURING MEDICAL FITNESS EXAMINTIONS OF COCKPIT AND CABIN CREWS Author(s) Name: Dr. Zoltán PÁCZ, Dr. Imre MELLES Introduction: With the average number of 3.500 oral cavity tumors detected yearly, Hungary occupies the first place in the world. The average being 3, 5-5 percent tumors - mainly among the male citizens, although the number of female patients is also growing. Although, it is not usually obligatory to do this as a part of a medical fitness examination, the ORL specialist of the Hungarian Aviation Medical Center is carefully controlling also the larynx and the oral cavity of the average 2200 airmen examined yearly, endeavoring to exclude preliminary precancerous signs of the mouth, especially the leukoplakia. Methods:Thanks to these efforts, we detect average 30-40 leukoplakia cases yearly among the examined persons. These cases can be successfully treated in initial period through medicine, excisions and Laser therapy. 5 % of these cases would turn bad or fatal without treatment. Results: In the past (during the last 20 years) we haven’t lost a single cockpit and cabin crew personnel with oral or larynx carcinoma, detecting and treating the precancerosus signs during medical fitness examinations on a very early stage. Conclusion: Keeping first place of the world list of oral cavity tumors and exits, the Hungarian Medical Center has to continue its good practice and service. Name and address for correspondence: Imre MELLES M.D. Telephone No.: 361 280 6809 Fax No.: 361 3580975 E-mail: melles@omfi.hu Date: 08/11/2008 ABSTRACT No 44. No 44. ABSTRACT Title: Stress Related Syndromes: a new nosographic approach to the psychiatric disfunctions in aircrew. Authors: Col. CSArn Prof. Gualberto ARDUINO - T.Col. CSArn Simeone IZZO Col. CSArn Domenico ABBENANTE- Discussion: As reported by the WHO the incidence of mood and anxiety disorders (dysthimia, depression, panic attack, phobia) is increasing and the “stress ” has been identified as one of the most significant agent in the etiology of this kind of illness and their related somathic disfunctions (cardiovascular, immunological, etc…) In fact, the neurobiological mechanisms of stress reaction are considered as important factors in the pathogenesis of many neuropsychological disfunctions (reduced cognitive performance and situational awareness, memory impairment, sleep disturbance and lack of attention, etc…). Several studies have well described the neuroanatomical and functional damages as consequence of chronic and acute stress and their role in the clinical syndromes. On the base of these evidences and in consideration of the new therapeutic protocols it is possible to consider a different policy in the evaluation and the treatment of some clinical syndromes, specially in the aircrew population which is known to try to avoid to be grounded. A nosographic approach that underline the “stress ” as etiopathogenetic factor, in alternative to the traditional diagnostic criteria, could be useful to lead to a more effective evaluation of the stress related syndromes in the perspective to achieve global results in terms of:prevention (psychoeducation, counseling, psychotherapy, problem solving, CRM, etc…); treatment (controlled use of new effective medications);more flexibility in evaluating the fitness in the renewal protocol of medical licence . If stated in the aviation medical rules, this kind of approach might encourage the affected personnel to undertake the right treatments and to be monitored by the medical authorities with the grounding time reduced to the minimum and more positive outcomes instead to hide the condition, look for inappropriate prescriptions and get self-medications. According to statistics data, in this case the risks to perform the flying duty in a compromised state and the chronicity of the condition are very high. With the current policy the paradox is that the “clever and safest ” people are grounded because of their acceptance to the treatment and the “least safe” can fly without any control. Conclusion: “Would you fly with this pilot ?”… a stressed pilot that hide his condition or take inappropriate drugs because of the rules and the consequences on his duty ? A new approach to the matter, in many cases, could allow to face an increasing problem with safe and defined strategies in order to protect this category of professionals. Name and address for correspondence: Col. Gualberto ARDUINO – Aviation Medicine Institute – Via P. Gobetti 2 – 00185 ROME (Italy) Telephone No.: +39-06 49865777 Fax No.: E-mail: gualberto.arduino@aeronautica.difesa.it Date: 17/09/2008 ABSTRACT No 45. Title: Respiratory CO2, as a physiological and neural-perception indicator of pilots' visual management, in aviation-A review Author(s) Name: Dr. Jayashri Devi Sharma MBBS MD Introduction: Glider pilots fly at near Earth-normal environmental conditions with adaptive mechanisms that are Physiological- normal responses including to those to hypoxia, hyperoxia, and hypercapnia. Gliding remained predominantly a European historical precursor of aviation as we know it today and flying around 10,000ft has always been believed to be within the physiological zone ( even with helicopters). Plasticity of Visual management during take off until final landing takes precedent importance over all other higher functions. Review of Methods:Aviation related respiratory gas changes were initially studied as cerebral-vaso-regulatory and sympathetic-parasympathetic baroreceptor and chemoreceptor induced adaptations, to operational requirements of extreme environments particularly, altitude and microgravity. The role of CO2 in a breath hold and re-breathing as an antidote to hyperventilation is remarkably consistent, resulting in better voluntary and autonomic cardio-respiratory balances. The human retinal circulation, like the whole cerebral circulation, has been shown to be strongly dependent upon PCO2 apparently outside strict autoregulatory controls. Phototransduction in the outer retina by photoreceptors, have a high metabolic rate, which generates large CO2 loads. Inner retina cells then process the visual signal by anion exchangers by removing photoreceptor-generated CO2 waste and maintain CO2-acid-balance. Further during dark adaptation to dimmer green flash stimuli, scotopic threshold sensitivity is delayed by hypoxia and hastened by hypocapnia and hyperoxia. Results: Visual function is a keystone parameter for good flying and hypercapnia has been shown to play a very important part in both blood flow to the retina and contrast sensitivity. Higher than normal CO2, (2.5%), concentration in air affects cell activities from the retina to the cortex, including the V1 area in the visual cortex, resulting in impaired coherent motion. Similarly low-concentration CO2 (2.5%) resulted in a temporary reduction in human stereoacuity, and a persistent but small increase in energy expenditure. Conclusion: The role of CO2 for visual perception and attentiveness in slow gliding flight in physiological zones or aggressive higher energy requiring flight, is most importantly a function of the air we breathe, hold, and exhale, in the atmosphere of Earth or Space. Name and address for correspondence: Dr. Jayashri Devi Sharma MBBS MD Glider Pilot B 205 Kendriya Vihar; Sector 56: Gurgaon , 122003 India Telephone No.: Mobile 91 11 9818617813 Fax No.: NIL E-mail: jayds@mail.jnu.ac.in Date: 7/10/2008 !!"#$%&' &()( * !!" (. & ! / '' 01 5#67(89(,(:-* / ,.. ;<==*,>,? #@).+ .2 .&3 ,$$ <##+#& ' + !!" (. ! ## ! $% , - !!" (. ! " ! $% &!'( # ! ## ))* *+ '! ,) ! ,) ! -###* +* ! .))/ &! $% !0 $% !0 1*23 .))#4 #*#### 0!= .))// 0!0 # (%# =! # /#F:### A,:/886( !'' !!" (. ! +(4#45 6*& 6( )#* )- A )9# )*# )*+# <*) )-$# #*9 .)B#C)A **$ ) *# **D#) +6 9)6-##)6-8 9).$# 9)6 -6 !!9 6 )6-6--/.% # )#*6"+ 76( 86. 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