Product Pipeline Overview

Product Pipeline Overview
The biotech R&D sector is dynamic and highly innovative. This overview gives an idea about the innovation spirit of some member companies
January 2014
of the Swiss Biotech Association. This overview will be updated regularly. The content is aimed at the stakeholder community of the industry.
The SBA Mission:
Contact
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The Swiss Biotech Association represents the interests of the biotech sector, supports the entrepreneurship of biotech companies, and
accrues value for them through the following activities:
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Development of optimal operation conditions for the biotech sector:
Dissemination of accomplishments in biotechnology:
For more information on
becoming a member of
SBA please contact:
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• Representation of the biotech interests to policy makers
• Support of:
• Knowledge and technology transfer
• Financing conditions for biotech companies
• Education and professional development
• To the political audience and to the general public
• Through the national biotech platform
• Increase of the visibility at national and international level
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Logo
Company
Product
Therapeutic Area
Indication
Partnering Status
4-Antibody
!"# !"#$#
Collaboration with strategic partners:
Stakeholders’ linking at national and international level:
• Through the development and maintenance of biotechnologyspecific platforms
• Organisation of and participation to national and international events
Notice: The information and data contained in this document are believed to be correct and are given in good faith. However, no liability, warranty or guarantee of final product
performance is created by this document. No freedom from any patent is granted or to be inferred. This document does not constitute a specification of any sort.
Preclinical
Phase I
Phase II
Phase III
Filing
On Market
Where
For more information on our products and licensing opportunities please contact info@4-antibody.com
AC Immune
ACI-24 (anti-Abeta vaccine)
CNS
Alzheimer´s Disease
AC Immune
Crenozumab (Anti-Abeta mAb)
CNS
Alzheimer´s Disease
AC Immune
ACI-812 (Abeta inhibitor)
CNS
Alzheimer´s Disease
AC Immune
ACI-35 (Tau Vaccine)
CNS
Alzheimer´s Disease
AC Immune
Anti-Tau mAb
CNS
Alzheimer´s Disease
AC Immune
Morphomer (Tau Inhibitor)
CNS
Alzheimer´s Disease
AC Immune
IVD (pTau, Abeta)
Diagnostic
Alzheimer´s Disease
AC Immune
PET Imaging Agent (Tau)
Diagnostic
Alzheimer´s Disease
AC Immune
ACI-24
Genetic Disorders
Down Syndrome
AC Immune
ACI-260
Ophtalmology
Glaucoma
Available
Addex Therapeutics
Dipraglurant (ADX48621)
CNS
Parkinson’s Disease Levodopa-induced Dyskinesia
Available
Addex Therapeutics
Dipraglurant (ADX48621)
CNS
DYT 1 Dystonia
Available
Addex Therapeutics
ADX71149
CNS
Anxious Depression
Janssen Pharmaceuticals Inc.
Addex Therapeutics
ADX71149
CNS
Schizophrenia
Janssen Pharmaceuticals Inc.
Addex Therapeutics
ADX71441
CNS
CNS
Available
Addex Therapeutics
mGluR2 NAM
CNS
not disclosed
Available
Discovery
Addex Therapeutics
mGluR4 PAM
CNS
Parkinson's Disease, MS
Available
Discovery
Addex Therapeutics
mGluR7 NAM
CNS
not disclosed
Available
Discovery
Addex Therapeutics
GLP1R PAM
Metabolic Disorders
Type 2 Diabetes
Available
Discovery
Addex Therapeutics
FSH NAM
Female Health
not disclosed
Available
Discovery
Addex Therapeutics
TNF-R1 NAM
Inflammation/CNS
not disclosed
Available
Discovery
Addex Therapeutics
A2A PAM
CNS
not disclosed
Available
Discovery
Addex Therapeutics
TrkB PAM
CNS
Neurodenegerative Disorders
Available
Discovery
AmVac
AMV100
Gynecology
Bacterial Vaginitis, Trichomoniasis
AmVac
AMV110
Urology
BPH, Prostatitis
AmVac
AMV601/602/603
Infectious Diseases
RSV
AmVac
AMV611
Infectious Diseases
RSV
AmVac
AMV401
Infectious Diseases
Pandemic Influenza
AmVac
AMV411
Infectious Diseases
Seasonal Influenza
Anergis
AllerT
Respiratory
Birch pollen allergy
Available
Anergis
AllerR
Respiratory
Ragwood pollen allergy
Available
Anergis
AllerDM
Respiratory
House dust mites allergy
Available
ARIAD Pharmaceuticals, Inc
Iclusig® (ponatinib)
Oncology
resistant/intolerant CML, Ph+ ALL
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
CML (newly diagnosed)
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
CML (Japanese patients)
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
Lung cancer (FGFR)
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
Ph+ ALL (newly diagnosed)
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
Gastrointestinal stromal tumors
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
Acute meloid leukemia
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
Lung cancer (RET)
ARIAD Pharmaceuticals, Inc
ponatinib
Oncology
Medullary thyroid cancer (RET)
ARIAD Pharmaceuticals, Inc
AP26113
Oncology
non-small cell lung cancer (ALK)
Baliopharm AG
ATROSAB
Inflammation
Rheumatoid Arthritis
Avaiable
Baliopharm AG
ATROSAB-MS
Inflammation
Multiple Sclerosis
Avaiable
Baliopharm AG
NOVOTARG
Inflammation
Multiple Sclerosis
Avaiable
Baliopharm AG
NOVOTARG
Cancer
Leukemia
Avaiable
Basilea Pharmaceutica
International AG
Toctino (alitretinoin)
Dermatology
Severe Chronic Hand Eczema refractory to potent
topical corticosteroids
Exclusive worldwide agreement with Stiefel
a GSK company
Basilea Pharmaceutica
International AG
Ceftobiprole
Infectious Diseases
Hospital treated Pneumonia
Available
Basilea Pharmaceutica
International AG
Isavuconazole
Infectious Diseases
Aspergillosis
Exclusive license, co-development and co-promotion
agreement with Astellas Pharma, Inc.
Basilea Pharmaceutica
International AG
Isavuconazole
Infectious Diseases
Candidemia
Exclusive license, co-development and co-promotion
agreement with Astellas Pharma, Inc.
Basilea Pharmaceutica
International AG
BAL30072
Infectious Diseases
Multidrug-resistant Gram-Negative Bacterial Infections
Basilea Pharmaceutica
International AG
BAL101553
Oncology
Taxane-resistant Cancer
Basilea Pharmaceutica
International AG
BAL19403
Dermatology
Moderate Inflammatory Acne
Available
Basilea Pharmaceutica
International AG
Anti-inflammatory Macrolide
Inflammation
COPD, Asthma, IBD, Psoriasis,
and other Inflammatory Disorders
Available
Exclusively licensed to Genentech
Exclusively licensed to Genentech
Discovery
pTau exclusively licensed to Genentech
Discovery
Discovery
U.S. and EU
Europe, Canada
Biogen Idec
For more information on our products and licensing opportunities please visit: www.biogenidec.ch
Biopartners GmbH
For more information on our products and licensing opportunities please contact: info@biopartners.ch
BioVersys
BV660
Infectious Diseases
Anti-Tuberculosis
Available
BioVersys
BV100
Infectious Diseases
Nosocomial Infections
Available
BV200
Infectious Diseases
Nosocomial Infections
Available
r-Urokinase
Cardiovascular
(thrombolytic)
Peripheral Arterial Occlusion - Catheter clearance etc.
Available
Covagen
COVA322 (bispecific anti-TNF/IL17A FynomAb)
Inflammation
RA, psoriatic arthritis, psoriasis, other
Available
Covagen
bispecific FynomAb
Inflammation
Covagen
COVA208 (anti-HER2 bispecific)
Oncology
Covagen
FynomAb
Covagen
BioVersys
• As a member of national and international umbrella organisations
• Through collaborations with life sciences clusters / initiatives
• With national and EC funding agencies
Projekt
Logoentwicklung Bioversys
Kunde
Bioversys
Datei
Datum
Projekt
2008-06-25
-
Beschreibung
Cerbios-Pharma SA
Logoentwicklung Phase 1
Version
Auflösung / Format
1
-
Freigabe Design
Freigabe Produktion
-
-
Lektor
Freigabe Kunde
Partnered with Mitsubishi Tanabe Pharma
diverse cancers
Available
Discovery
Oncology
Available
Discovery
FynomAb
Oncology
Available
Discovery
CT Atlantic AG
Human-Derived Antibodies
Oncology
Cytos
CYT003
Respiratory
Allergic Asthma
Cytos
CYT003
Respiratory
Allergic Rhinitis
Cytos
CAD106
CNS
Alzheimer's Disease
Novartis
Cytos
PF-06444753/752
Respiratory
Allergic Rhinitis
Pfizer
Cytos
gH-Qb VLP
Infectious diseases
Influenza
Government of Singapore
Cytos
CYT012 (Fel-Qb VLP)
Respiratory
Cat Allergy
Cytos
CSP-Qb VLP
Infectious diseases
Malaria
Debiopharm
Debio 8206 CPP
Endocrinology
Central Precocious Puberty
Debiopharm
Debio 025/Alisporivir
Infectious diseases
HCV
Licensed to Novartis worldwide except Japan
Debiopharm
Debio 0932 NSCLC
Oncology
NSCLC
in development
Debiopharm
Debio 025
Infectious diseases
HCV
Available in Japan
Debiopharm
Debio 1143
Oncology
Solid tumors
in development
Debiopharm
Debio 1347
Oncology
advanced solid tumors with FGFR alterations
in development
Debiopharm
Debio 0930
Metabolic diseases
diabetes
Available
Debiopharm
Debio 1144
Oncology
Solid tumors
Not available
Debiopharm
Debio 0617
Oncology
in development
Debiopharm
Debio 1036
Autoimmune diseases
Not available
Debiopharm
Debio 0929
Oncology
Debiopharm
Debio 0826
Oncology
Discovery
Debiopharm
Debio 1348
Infectious diseases
Discovery
Debiopharm
Debio 1246
Oncology
Discovery
Delenex Therapeutics AG
DLX105
Inflamation
Behçet’s disease
Available
Delenex Therapeutics AG
DLX105
Dermatology
Psoriasis
Available
Delenex Therapeutics AG
DLX2560
Dermatology/Inflamation
Available
Delenex Therapeutics AG
DLX2323
Dermatology/Inflamation
Available
Delenex Therapeutics AG
DLX2201
Dermatology
Available
Delenex Therapeutics AG
DLX1008
Dermatology/Oncology
Available
Delenex Therapeutics AG
DLX521
Oncology
Available
Delenex Therapeutics AG
DLX212
CNS
Available
Dybly
DYB186
Cardiovascular
For more information on our products and licensing opportunities please contact: info@ct-atlantic.com
HDL stimulation, Bromodomain inhibition
WRAIR (CRADA)
Available
EffRx Pharmaceuticals SA
For more information on our products and licensing opportunities please contact: info@effrx.com
Evolva
For information on our ingredients, please visit www.evolva.com/products
Data verified by Biotechgate.com, part of Venture Valuation.
Swiss Biotech Association
Wengistrasse 7
CH-8004 Zurich
Tel. +41 (0)44 455 56 78
Fax +41 (0)44 786 16 81
www.swissbiotech.org
info@swissbiotech.org
Logo
Company
Product
Therapeutic Area
Indication
Partnering Status
Finox AG
BEMFOLA
Women's Health/
Reproductive Health
Superovulation/ Induction of ovulation /
Spermatogenesis
Preclinical
Phase I
Phase II
Phase III
Available
Gene Signal
Aganirsen
Ophthalmology Orphan
Corneal Neovascularisation in Graft patients (CNV-CG)
Gene Signal
Aganirsen
Ophthalmology Orphan
Neovascular Glaucoma (NVG)
Gene Signal
Aganirsen
Ophthalmology Orphan
Retinopathy of Prematurity (ROP)
Gene Signal
Aganirsen
Ophthalmology - NonOrphan
wet Age Related Macular Degeneration
(wet AMD)
Gene Signal
Aganirsen
Ophthalmology - NonOrphan
Diabetic Macular Edema in Diabetic Retinopathy (DME)
Gene Signal
Aganirsen
Dermatology
Psoriasis
GeNeuro SA
GNbAC1
Neurology
CIDP-Neuropathy
Available
GeNeuro SA
GNbAC1
CNS
MS
Available
GeNeuro SA
GNbAC1
CNS
Schizophrenia
Available
GeNeuro SA
GNbAC2
Metabolism
Type 1 diabetes
Available
Glenmark
Crofelemer
Gastrointestinal
HIV related Diarrhea
In-licensed for ROW markets
Glenmark
Crofelemer
Gastrointestinal
Adult Acute Infectious Diarrea and Cholera
In-licensed for ROW markets
Glenmark
Vatelizumab
Inflammation
Ulcerative Colitis
Out-licensed to Sanofi
Glenmark
mPGES-1 inhibitors
Inflammation/Pain
Chronic imflammatory conditions including Pain
Glenmark
GRC 15300
Pain
Neuropathic Pain
Outlicensed to Sanofi
Glenmark
GRC 17536
Pain
Neuropathic Pain
Available
Glenmark
GRC 17536
Respiratory
Respiratory Disorders
Available
Glenmark
GBR 900
Pain
Chronic Pain
Available
Glenmark
GBR 830
Immunology
Autoimmune Disorders
Available
GlycoVaxyn AG
Pneumo Glycoconjugate Vaccine
Infectious Diseases
Staphylococcus pneumoniae
Available
GlycoVaxyn AG
Shigella Glycoconjugate Vaccine
Infectious Diseases
Shigella
Available
GlycoVaxyn AG
Staphylococcus aureus
Glycoconjugate Vaccine
Infectious Diseases
Staphylococcus aureus
Available
Horizon Pharma, Inc.
Lodotra (Rayos)
Rheumatology
Rheumatoid Arthritis and other musculoscelatal
Partnered in Europe, Asia Pacific, LATAM
EU, US, Australia, South Korea
Horizon Pharma, Inc.
Duexis
Pain, musculoscelatal
Osteoarthritis
ex US pending
US
Humabs BioMed SA
CMV MoAb
Viral Infection
CMV
Partnered
Humabs BioMed SA
Flu MoAb
Viral Infection
Flu A and B
Partnered
Humabs BioMed SA
RSV/MPV MoAb
Viral Infection
RSV/MPV
Available
Humabs BioMed SA
HBV MoAb
Viral Infection
Chronic HBV infection
Available
Humabs BioMed SA
Dengue MoAb
Viral Infection
Dengue Fever
Available
Humabs BioMed SA
JCV/BKV Moabs
Viral Infection
Transplant and immuncompromized patients
Available
Humabs BioMed SA
Rabies Moab
Viral Infection
Therapeutic after exposure
Available
Humabs BioMed SA
S aureus MoAb
Bacterial Infection
Sepsis, Pneumonia
Available
Humabs BioMed SA
Cytokine MoAbs
Autoimmunity
TBD
Available
Humabs BioMed SA
Anti Tumor MoAbs
Cancer
TBD
Available
Kenta Biotech
Panobacumab, KBPA101
Anti-infectives
Nosocomial Pneumonia
Available
EU
Kenta Biotech
KBPA104 (monoclonal antibody)
Anti-infectives
Nosocomial Pneumonia
Available
EU
Kenta Biotech
KBSA301 (monoclonal antibody)
Anti-infectives
Staphylococcus aureus Infections
Available
EU
Kenta Biotech
KBRV201 (monoclonal antibody)
Anti-infectives
RSV infections
Available
Kenta Biotech
KBAB401 (monoclonal antibody)
Anti-infectives
Acinetobacter baumanii Infections
Kuros Biosurgery AG
KUR-111
Trauma
Tibia Plateau Fractures
Kuros Biosurgery AG
KUR-112
Trauma
Bone Cysts (Orphan)
Kuros Biosurgery AG
KUR-113
Trauma
Tibial Shaft Fractures
Kuros Biosurgery AG
KUR-212
Wound
Mesh Burns
Kuros Biosurgery AG
KUR-213
Wound
Abdominoplasty
Kuros Biosurgery AG
KUR-023
Wound
Dural Sealant
Kuros Biosurgery AG
KUR-115
Spine
Spinal Fusion
Lumavita AG
For more information on our products and licensing opportunities please contact: info@lumavita.com
Med Discovery SA
For more information on our products and licensing opportunities please contact: info@med-discovery.com
Molecular Partners
For more information on our products and licensing opportunities please contact info@molecularpartners.com
Mymetics Corporation
For more information on our products and licensing opportunities please contact: info@mymetics.com
Nano Bridging Molecules SA
SurfLink®
Dental Implants
Osseointegration
Filing
On Market
Where
CE marked Medical Device
NBE Therapeutics
For more information on our products and licensing opportunities please contact info@nbe-therapeutics.com
Neurimmune Therapeutics AG
NI-101
CNS
Alzheimer’s disease
partnered with Biogen Idec
Neurimmune Therapeutics AG
NI-202
CNS
Parkinson’s disease
partnered with Biogen Idec
Neurimmune Therapeutics AG
NI-105
CNS
Alzheimer’s disease
partnered with Biogen Idec
Neurimmune Therapeutics AG
NI-205
CNS
Neurodegenerative disease
partnered with Biogen Idec
Neurimmune Therapeutics AG
NI-203
CNS
Amyotrophic Lateral Sclerosis
Available
neurotune
NT-11624
Neuropathic Pain
Anti-Retroviral Therapy Induced Pain,
Osteoarthritic Pain
Partnered
neurotune
NT-13317/24336
Neuropathic Pain
Chemotherapy-Induced Pain, Diabetic Neuropathy
Partnered
neurotune
NT-biological
Musculo-Skeletal
Sarcopenia, Neuromuscular Diseases
Available
neurotune
NT-small molecules
Musculo-Skeletal
Sarcopenia
Available
neurotune
Diagnostic
Musculo-Skeletal
Sarcopenia, Kidney Disorders
Available
NovImmune
NI-0401
Autoimmune /
Inflammatory
Transplant; Crohn’s Disease
Available
NovImmune
NI-0801
Inflammatory
Primary Biliary Cirrhosis (PBC), others
Available
NovImmune
NI-0701
Inflammatory
N/A
Available
NovImmune
NI-0501
Autoimmune /
Inflammatory
Hemophagocytic
NovImmune
NI-1401
Autoimmune /
Inflammatory
N/A
Partnered with Genentech/Roche
NovImmune
NI-0101
Autoimmune /
Inflammatory
N/A
Available
NovImmune
NI-1201
Inflammatory
N/A
Available
NovImmune
NI-1601
Oncology
Cancer
Available
Discovery
NovImmune
NI-1701
Oncology
Cancer
Available
Discovery
Numab
ND003
Respiratory
Asthma / COPD
Partnered
Numab
ND004
Pain
Proprietary
Numab
ND007
Autoimmune/
Inflammatory
Proprietary
Numab
ND009
undisclosed
Partnered
Lymphohistiocytosis (HLH)
Available
Orphanbiotec AG
For more ifnormation on our products and licensing opportunities please contact: kontakt@orphanbiotec.com
PharMida AG
Transbucal Insulin
Metabolic Diseases
Diabetes
PharMida AG
Transbuccal GLP-1
Metabolic Diseases
Diabetes
Philochem/Philogen
L19-131I
Oncology
Hodkin Lymphoma
Available
Europe
Philochem/Philogen
L19-TNF + doxorubicine
Oncology
Sarcoma
Available
Europe
Philochem/Philogen
L19-IL2 + dacarbazine
Oncology
Melanoma
Available
Europe
Philochem/Philogen
L19-IL2 + L19-TNF
Oncology
Melanoma (intralesional)
Available
Europe
Philochem/Philogen
L19-IL2 + gemcitabine
Oncology
Pancreatic Cancer
Available
Europe
Philochem/Philogen
F16-IL2 + cytarabine
Oncology
AML
Available
Europe
Philochem/Philogen
F16-IL2 + paclitaxel
Oncology
Breast Cancer
Available
Europe
Philochem/Philogen
F16-IL2 + paclitaxel
Oncology
Merkel Cell Carcinoma
Available
Europe
Philochem/Philogen
F8-IL10 + methotrexate
Chronic Inflammation
Rheumatoid Arthritis
Pfizer
Europe
Philochem/Philogen
F8-IL4
Chronic Inflammation
Psoriasis
Available
Europe
Proreo Pharma
Nepolong (R)
Cardio-Vascular
Pulmonary Hypertension
available
Proreo Pharma
PP-012
CNS
Aura Migraine
in preparation
Infectious Diseases
CMV, Influenza
Available
Redbiotec AG
Negotiations
Santhera
Catena ® Neurology
Primary progressive Multiple Sclerosis
Santhera
Catena ®
Neuromuscular,
Neurology
Duchenne Muscular Dystrophy
Santhera
Raxone ®
Senexta Therapeutics SA
SNX-001
CNS
Alzheimer’s Disease
Available
Senexta Therapeutics SA
SNX-001
CNS
Post Stroke Cogntive Impairment
Available
Sompharmaceuticals S.A.
Somreotide
Endocrinology
Resistant Acromegaly
Available
Sompharmaceuticals S.A.
Somreotide
Oncology
Resistant Neuroendocrine Tumours
Available
Sompharmaceuticals S.A.
SomtoScan
Diagnostics/Imaging
Neuroendocrine Tumours
Available
Stemedica
ischemic tolerant Mesenchymal
Stem Cells (itMSC)
Neurology
Ischemic stroke
Available
USA
Stemedica
ischemic tolerant Mesenchymal
Stem Cells (itMSC)
Cardiovascular
Acute Myocardial Infarction
Available
USA
Stemedica
ischemic tolerant Mesenchymal
Stem Cells (itMSC)
Cardiovascular
Acute Myocardial Infarction
Not available
KH
Stemedica
ischemic tolerant Mesenchymal
Stem Cells (itMSC)
Dermatology
Skin Photoaging
Not available
USA
Stemedica
ischemic tolerant Mesenchymal
Stem Cells (itMSC)
Neurology
Alzheimer's disease
Available
CH
Stemedica
ischemic tolerant Mesenchymal
Stem Cells (itMSC)
Ophtalmology
Diabetic retinopathy
Available
USA
Stemedica
ischemic tolerant Neural Stem Cells
CNS
Spinal Cord Injury
Available
USA
Leber's Hereditary Optic Neuropathy
Stemergie Biotechnology SA
For more information on our products and licensing opportunities please contact: info@stemergie.com
Stragen Pharma
For more information on our products and licensing opportunities please contact info@stragen.ch
Telormedix SA
TMX-101
Oncology
Bladder Cancer
Available
Telormedix SA
TMX-202
Oncology
Tumor Immunology
Available
Telormedix SA
TMX-30X
Immunology
Inflammation/Autoimmune Diseases
Available
Telormedix SA
TMX-20X
Immunology/Oncology
Vaccine Adjuvant/Tumor immunology
Available
Virometix
VMT-01
Inectious Diseases
Next-generation Pneumococcal Vaccine
Available
Virometix
VMT-02
Oncology
Cervical Cancer Vaccine
Available
Discovery
Virometix
VMT-03
Respiratory
RSV
Available
Discovery
Virometix
VMT-04
Oncology
Available
Discovery
Data verified by Biotechgate.com, part of Venture Valuation.