Preliminary Agenda for Part II
Transcription
Preliminary Agenda for Part II
International Academy of Life Sciences and University of Massachusetts Boston present International Life Sciences Workshops Series: "Decision-Making in Biomedical Science – Meet the Experts" PART 2: Biomarkers, Analysis, and Implementation MARCH 6 – 10 | 2015 Potsdam | Germany Data and Life Sciences: A Vital Learning Opportunity in Two Parts IALS and the University of Massachusetts Boston are pleased to offer Part 2 in the new International Life Sciences Workshop Series, “Biomarkers, Analysis, and Implementation.” This four-day workshop continues the learning begun in “Introductions and Foundations,” held September 2014. These two seminars – which are strongest taken as a series, but accessible also as individual workshops – provide an opportunity for all participants and faculty to reach beyond their traditional spheres of influence to engage in spirited and detailed dialogs with experts who cross industry, academic, and geographic boundaries. “Master Class” in Biomedical Science Modeled after the Master Class in the Arts, we intend for this new “Master Class in Biomedical Science – Meet the Experts” series to foster special relationships between participants and lecturers, leading to knowledge sharing and the discussion of larger ethical issues among younger and more experienced scholars and professionals. Our diverse and dynamic faculty brings vertical expertise in specific areas of data mining / management; vertical expertise in evidence-based medicine; and horizontal expertise to bridge and integrate the two areas for real-life applications. Integrating these two particular vertical worlds for immediate applications is a new concept in advanced medical learning. Designed for Professionals The unique workshop series has been designed for a very select group of professionals: Biomedical post-graduates, researchers, faculty, group leaders, and clinical scientists. This ground-breaking program links Big Data and Medicine, providing the basics of data management and data mining, with practical applications for specific areas of evidence-based medicine, quality management, and clinical research. This two-part program is a unique opportunity for professionals and faculty alike to expand their knowledge of one of the most important tools in medicine today. 1|P ag e Connecting Informatics and Life Sciences Life Science today is becoming increasingly complex, more global, and more data-based. The importance of molecular biology and translational medicine to all aspects of Life Sciences is greater than ever, and will continue to grow in the coming years. The sheer volume of data amassed on a daily basis from the broad scope of research, medicine, and clinical practice can be a gold mine of valuable information that can influence diagnoses, decision making, and quality management at all levels of medicine. This Workshop series will provide the basis for mining, managing, analyzing, and applying data to real-world challenges specifically faced by those in the Life Sciences community. Please join us. PROF. HILMAR STOLTE, M.D. Univ.Prof.em. & President IALS Medizinische Hochschule Hannover Hannover stolte@lifesciences.net FORUM NEUER MARKT NEW MARKET SQUARE Potsdam’s Forum Neuer Markt is unique in bringing together a number of cultural institutions and centers for research into the humanities. The subjects range from the European Enlightenment to the history of Brandenburg and Prussia; from the culture and history of the Germans in Eastern Europe to the study of Jewish life past and present; from contemporary German history in its European context to modern philosophy, film history, scholarly editions of works by Kant, Leibniz and Jean Paul and the study of medieval stained glass. It’s an ideal setting for ongoing learning and cultural experiences, and the home of the IALS Potsdam office (far right). 2|P ag e PROF. WINSTON LANGLEY, PH.D. Provost and Professor Political Science University of Massachusetts Boston Boston winston.langley@umb.edu International Life Sciences Workshops Series: "Decision-Making in Biomedical Science – Meet the Experts " Part 2 Agenda: Biomarkers, Analysis, and Implementation LOCATION Le Manége Haus der Brandenburgisch-Preußischen Geschichte Am Neuen Markt 9 14467 Potsdam, Germany FRIDAY, 6 MARCH, 2015 13:00 WELCOME HILMAR STOLTE | Potsdam ROBERT PRICE | London 13:30 17:00 SESSION 1: TRIALS RCTS AND DECISION - MAKING AXEL MÜHLBACHER | Neubrandenburg 15:00 15:30 BREAK MAKING USE OF ROUTINE CLINICAL DATA: APPLICATIONS AND LIMITATIONS MICHAEL MARSCHOLLEK | Hannover 17:00 18:00 "MEET THE EXPERTS” 18:00 RECEPTION / BUFFET LE MANÈGE: A beautifully restored meeting space for our International Workshop, on the campus of the Haus der BrandenburgischPreussischen Geschichte. 3|P ag e Photo: http://www.kutschstall-potsdam.de/kutschstall.html SATURDAY, 7 MARCH, 2015 9:00 BREAKFAST Mercure Hotel 9:30 13:00 SESSION 2: DATA REPOSITORIES, DATA ANALYSIS, BIOMARKERS DATA REPOSITORIES ON THE WEB Dan Simovici | Boston 11:00 11:30 BREAK MAKING USE OF ROUTINE DATA FROM HEALTH INSURANCES DATA SIEGFRIED GEYER | Hannover 13:00 14:00 LUNCH 14:00 16:00 NETWORKING & CULTURAL EXPERIENCE: Tour of Marmorpalais & Schloss Cecilienhof FREE EVENING SANS-SOUCI PALACE in Potsdam Photo: Raimond Spekking via Wikimedia Commons 4|P ag e SUNDAY, 8 MARCH, 2015 IALS BMEP 35 YEAR CELEBRATION LOCATION: Le Manége Haus der Brandenburgisch-Preußischen Geschichte Am Neuen Markt 9 14467 Potsdam, Germany 11:00 WELCOME PROF. HILMAR STOLTE, M.D., President IALS Medizinische Hochschule Hannover IALS 35 YEARS: SCIENCE & INTERNATIONALIZATION MODERATOR: PROF. KARSTEN DREINHÖFER, M.D. Chairman IALS Development Committee Charité Universitätsmedizin Berlin PROF. HERMANN HALLER, M.D. Associate Dean for International Affairs Medizinische Hochschule Hannover PROF. ROLAND HETZER, M.D. Former Chairman, Deutsches Herzzentrum Berlin PROF. ROBERT PRICE, PH.D. Prof. em. Biochemistry, King’s College London IALS Board Member 12:00 5|P ag e LUNCH SPECIAL LECTURES 13:00 COMPUTERS, AUTOMATION, AND MEDICAL CARE PROF. JEROME KASSIRER, M.D. Distinguished Professor, Tufts University School of Medicine Editor-in-Chief Emeritus, New England Journal of Medicine 14:00 BREAK 14:15 BIOMARKERS & BIOMONITORING PROF. JILL MACOSKA, PH.D. Alton J. Brann Endowed Distinguished Professor of Science and Mathematics, Professor of Biological Sciences Director, Center for Personalized Cancer Therapy University of Massachusetts Boston 15:15 BREAK 15:30 THE MAKING OF A CLINICAL SCIENTIST IN SURGERY PROF. HANS-CHRISTOPH PAPE, M.D. F.A.C.S. Chairman, Department of Orthopaedic Trauma RWTH- Aachen 16:30 18:30 ALUMNI SOCIAL NETWORKING / BUFFET HAUS DER BRANDENBURGISCH-PREUSSISCHEN GESCHICHTE (House of Brandenburg-Prussian History). Forum Neuer Markt The New Market Square, Potsdam's most beautiful square, is an architectural jewel. Almost completely spared from the destruction of war and lovingly restored in the 1990s, it is Potsdam's only town square which remains nearly the same as it was in the 18th century. Under the direction of Frederick II, townhouses were built on the square now known as the Neuer Markt. The New Market Square, home to a number of scientific institutions, is a center for the humanities in Potsdam today. Our International Workshop is held at La Manège, on the museum campus. http://www.potsdam.de/node/276475 6|P ag e MONDAY, 9 MARCH, 2015 9:00 BREAKFAST Mercure Hotel 9:30 13:00 SESSION 3: BIOINFORMATICS, CLINICAL DATA MANAGEMENT CLINICAL TRIAL STRATEGIES IN BIOTECH AND PHARMA: LEARNING FROM SUCCESSES AND MANEUVERING THE KNOWN PITFALLS ELMAR BURCHARDT | Cambridge 11:00 11:30 BREAK VISUALIZATION OF DATA AND QUALITY ASSURANCE IN HEMODIALYSIS PATIENTS CLAUDIA BARTH | Melsungen 13:00 14:00 LUNCH 14:00 15:30 BIOINFORMATICS I HANS BINDER | Leipzig 15:30 16:00 BREAK DATA MANAGEMENT AT A REGISTRY FOR PATIENTS WITH MECHANICAL CIRCULATORY SUPPORT JAN GUMMERT | Bad Oeynhausen 17:30 18:00 “MEET THE EXPERTS” FREE EVENING DIE WAAGE: Historic Potsdam City Scales building, now a restaurant in the Forum Neuer Markt. 7|P ag e TUESDAY 10 MARCH, 2015 9:00 BREAKFAST Mercure Hotel 9:30 13:00 SESSION 4: BIOINFORMATICS, DATA QUALITY, CONCLUSION CLINICAL DATA MANAGEMENT: QUALITY ASSURANCE AND INDIVIDUALIZED PATIENT CARE WILFRIED GWINNER | Hannover 11:00 11:30 BREAK BIOINFORMATICS II HANS BINDER | Leipzig 8|P ag e 13:00 14:00 PROGRAM WRAP UP AND DISCUSSION HILMAR STOLTE | Potsdam ROBERT PRICE | London 14:00 OPTIONAL: LUNCH & TOUR OF LEIBNIZ INSTITUTE FOR ASTROPHYSICS PART 2: BIOMARKERS, ANALYSIS, AND IMPLEMENTATION ORGANIZING COMMITTEE PROF. MICHAEL MARSCHOLLEK, M.D. Peter L. Reichertz Institute for Medical Informatics University of Braunschweig - Institute of Technology and Hannover Medical School Hannover Michael.marschollek@plri.de PROF. HOLGER SCHÜNEMANN, M.D., PH.D. Professor and Chair, Department of Clinical Epidemiology and Biostatistics McMaster University Health Sciences Centre Hamilton schuneh@mcmaster.ca PROF. DAN SIMOVICI, PH.D. Department of Computer Science University of Massachusetts Boston Dan.simovici@umb.edu JENS STEINBRINK, PH.D. Managing Director of the Center for Stroke Research Berlin Charité Universitätsmedizin Berlin Vice President IALS University Network Berlin Jens.Steinbrink@charite.de POTSDAM STADTSCHLOSS, renovated in 2013, seen from the Havel River. The Hotel Mercure is to the left, and Forum Neuer Markt is close by. 9|P ag e Photo: Roland.h.Bueb via Wikimedia Commons PART 2: BIOMARKERS, ANALYSIS, AND IMPLEMENTATION SPONSORS For more information, see IALS Life Sciences University Network Integrated Research and Treatment Centers Center for Stroke Research Berlin of 10 | P a g e of of PART 2: BIOMARKERS, ANALYSIS, AND IMPLEMENTATION FACULTY PROF. CLAUDIA BARTH, M.D., HEALTH ECONOMIST (ebs) Chief Medical Officer B.Braun Avitum Melsungen IALS Development Committee claudiabarth@aol.com HANS BINDER, PH.D., DR.HABIL. Director Interdisciplinary Center for Bio Informatics, IZBI Universität Leipzig Leipzig binder@izbi.uni-leipzig.de ELMAR R. BURCHARDT, M.D., PH.D, D.SC. CEO, President and Director Hemostemix, Inc. Boston eburchardt@hemostemix.com PROF. KARSTEN DREINHÖFER, M.D. Chairman IALS Development Committee Charité Universitätsmedizin Berlin Medical Park Berlin Humboldtmühle Berlin karsten.dreinhoefer@charite.de PROF. SIEGFRIED GEYER, PH.D. Director Medical Sociology Unit Medizinische Hochschule Hannover Hannover Geyer.siegfried@mh-hannover.de 11 | P a g e PROF. JAN F. GUMMERT, M.D., PH.D. Director of the Department for Thoracic and Cardiovascular Surgery Heart and Diabetes Center NRW Ruhr Universität Bochum Bad Oeynhausen, Germany jgummert@hdz-nrw.de PROF. WILFRIED GWINNER, M.D. Department of Nephrology Medizinische Hochschule Hannover Hannover wgwinner@t-online.de PROF. HERMANN HALLER, M.D. Associate Dean for International Affairs Medizinische Hochschule Hannover Hannover Haller.Hermann@mh-hannover.de PROF. ROLAND HETZER, M.D., PH.D. Former Chairman, Deutsches Herzzentrum Berlin Berlin hetzer@dhzb.de PROF. JEROME KASSIRER, M.D. Distinguished Professor, Tufts University School of Medicine Editor-in-Chief Emeritus, New England Journal of Medicine Boston jpkassirer@gmail.com PROF. JILL A. MACOSKA, PH.D. Alton J. Brann Endowed Distinguished Professor of Science and Mathematics Professor of Biological Sciences Director, Center for Personalized Cancer Therapy University of Massachusetts Boston Boston Jill.Macoska@umb.edu 12 | P a g e PROF. MICHAEL MARSCHOLLEK, M.D., M.SC., PH.D. Acting director, PLRI Site at Hannover Medical School Peter L. Reichertz Institute for Medical Informatics University of Braunschweig - Institute of Technology and Medizinische Hochschule Hannover Hannover Michael.marschollek@plri.de PROF. DR. AXEL C. MÜHLBACHER IGM Institut Gesundheitsökonomie und Medizinmanagement Hochschule Neubrandenburg Fachbereich Gesundheit, Pflege, Management Neubrandenburg muehlbacher@hs-nb.de PROF. HANS CHRISTOPH PAPE, M.D., F.A.C.S. Chairman, Department of Orthopaedic Trauma RWTH- Aachen Aachen hpape@ukaachen.de PROF. ROBERT PRICE, PH.D. Prof. em. Biochemistry IALS Board Member King’s College London London Robert.price@kcl.ac.uk PROF. DAN SIMOVICI, PH.D. Department of Computer Science University of Massachusetts Boston Dan.simovici@umb.edu PROF. HILMAR STOLTE, M.D. Univ.Prof.em. & President IALS Medizinische Hochschule Hannover Hannover stolte@lifesciences.net 13 | P a g e 1. 2. 3. 4. 5. 6. 7. 8. Mercure Hotel Potsdam City, Lange Brücke Le Manége, (Conference location), Am Neuen Markt 9 IALS Office, Forum Neuer Markt Central Station Potsdam, Lange Brücke Landtag Schloss Marmorpalais Schloss Cecilienhof Einstein Tower 2 3 5 1 4 7 6 14 | P a g e 8 The Potsdam Conference at Schloss Cecilienhof, August 1945. Here, the three powers were represented by Prime Minister Winston Churchill, President Harry S. Truman, and Communist Party General Secretary Joseph Stalin. International Life Sciences Workshops Series: "Decision-Making in Biomedical Science – Meet the Experts" PART 2: Biomarkers, Analysis, and Implementation MARCH 6 – 10 | 2015 Potsdam | Germany FACULTY BACKGROUND PROF. CLAUDIA BARTH, M.D. HEALTH ECONOMIST (ebs) Chief Medical Officer B.Braun Avitum AG, Melsungen IALS Development Committee claudiabarth@aol.com HANS BINDER, PH.D., DR.HABIL. Director Interdisciplinary Center for Bio Informatics, IZBI Universität Leipzig Leipzig binder@izbi.uni-leipzig.de 15 | P a g e Dr. Barth is Chief Medical Officer B.Braun Avitum AG. B. Braun provides renal care to >22.000 patient in > 25 countries and is a leading medical device company for renal replacement therapy producing machines, filters and disposables. Claudia Barth is in charge of all quality assurance aspects in medicine and nursing, implementation of new concepts and structure of medical care, support of reimbursement in providing care for dialysis and kidney patients, clinical studies, continuous scouting for innovation in treatment modalities. 2003-2013: Chief Medical Officer and Member of the Management Board of the KfH Kuratorium für Dialyse und ierentransplantation (Curatorium for Dialysis and Renal Transplantation) serving 1/3 of the German dialysis population, covering 200 kidney centers for adults and 15 kidney centers for children and adolescents. Chief Medical and Technical Officer (board member) of the GML AG providing full technical service for hospitals/ dialysis centers Chief medical Officer KfH Foundation for Preventive Medicine supporting clinically oriented research to prevent kidney disease. Since 2007 associate professorship in internal medicine at the University Hospital of Cologne. 2001-2003: Head of clinical affairs Janssen Cilag GmbH, Johson& Johnson. 1987-2003: internal medicine and nephrology - University Hospital of Cologne, degree in health economics - European Business School, Germany. DFG Research Fellow Harvard Medical School, Boston, transplantation immunology MD degree from Hannover Medical School, Germany - participant BMEP program 1985/1986 Tufts Medical School, Boston and Albert Einstein College of Medicine, New York City, USA. Research expertise in basic science is in transplantation immunology, epidemiological data analysis from dialysis patient treatment data bases Dr. Binder is a Biophysicist by training and worked for many years on biomembranes using computer simulations and optical spectroscopy. Later, his interests changed to bioinformatics where he developed sophisticated calibration methods for microarray expression data using physico-chemical models. Since more than ten years he is managing director of the Interdisciplinary Centre for Bioinformatics of the University of Leipzig. His group is involved in numerous studies discovering the molecular background of complex diseases such as cancer using data-driven mining and hypothesis-driven modeling approaches with the special focus on gene-regulatory mechanisms caused by genetic and epigenetic dysfunctions. For these applications, he, together with his coworkers, develops methods of class discovery, feature selection, and function mining for high-dimensional omics data using machine learning and particularly self-organizing maps. These methods are applied to different cancer entities such as glioma, lymphoma, colon cancer, and melanoma, and also to different kinds of civilization diseases studied in the frame of the LIFE center for civilization diseases. ELMAR R. BURCHARDT, M.D., PH.D, D.SC. CEO, President and Director Hemostemix, Inc. Boston eburchardt@hemostemix.com. Immediately prior to joining Hemostemix as CEO, Dr. Burchardt was vice president of regenerative medicine at Pfizer, Inc. in Cambridge, Massachusetts, USA. Pfizer was the first large pharmaceutical company to develop clinical cell therapies in international multicenter trials. Before his appointment at Pfizer, he worked as vice president of medical affairs for Aastrom Biosciences in Ann Arbor, Michigan, USA. He initiated and led Aastrom’s US-based clinical cell-therapy programs in cardiovascular diseases such as critical limb ischemia (CLI) and dilative cardiomyopathy (DCM). Previously, he worked for Miltenyi Biotec GmbH in Germany as medical director, with global responsibilities including the development and market introduction strategy of 10 new clinical cell therapy products. Before that, Elmar worked for Bayer AG in Germany. He studied medicine and biochemistry in Hannover, at Yale University in New Haven, Connecticut, USA, and at the Max Delbruck Center of Molecular Medicine in Berlin, Germany. He holds MSc and PhD degrees in biochemistry and an MD degree from Hannover Medical School in Hannover, Germany, and is an adjunct professor at the University of Witten Herdecke in Witten, Germany. Elmar has more than 20 years of experience with the development of innovative therapies. PROF. KARSTEN DREINHÖFER, M.D. Chairman IALS Development Committee Charité Universitätsmedizin Berlin Berlin karsten.dreinhoefer@charite.de Dr. Dreinhöfer is a specialist in orthopedics and trauma surgery, social medicine, physical therapy, emergency medicine, osteology (DVO), chiropractic therapy and health economy (ebs). One of his main scientific interests is Health Service Research. In 2009, he was appointed Head of the Department of Orthopedics and Traumatology at Medical Park in Humboldtmühle, Berlin, as well as Chair of the Department of Musculoskeletal Prevention, Rehabilitation and Health Services Research at the Center for Musculoskeletal Surgery at Charité Universitätsmedizin and Humboldt University. Other appointments include the European Board of Johnson & Johnson Orthopedics in 1997 and Deputy Head of the Department of Orthopedics, University of Ulm, in 2001. Prof. Dreinhöfer is a member of the Executive Board of the Professional Association of Specialists in Orthopedic and Traumatology (BVOU) and of the Board of the European Federation of National Associations of Orthopedics and Traumatology (EFORT). He is editor of the German Orthopaedic Societies journal and is also Director of Development for the International Bone and Joint Decade. Prof. Dreinhöfer holds degrees in Medicine and Health Economy (ebs) from Hannover Medical School and the European Business School in Oestrich-Winkel, respectively. PROF. SIEGFRIED GEYER, PH.D. Director Medical Sociology Unit Medizinische Hochschule Hannover Hannover Geyer.siegfried@mh-hannover.de Professor Geyer is directing the Medical Sociology Unit at Hannover Medical School. His research interests are on the role of social/ psychological factors in the course of disease, and morbidity compression as the present main project. The first line of research includes epidemiological studies with large registry-based datasets from statutory health insurances. These are being used for health care research, in particular for examining morbidity compression, for evaluating inpatient rehabilitation, and for studies on the utilization of screening programmes. Another current project deals with selectivities in the transplantation of kidneys and with the length of survival after transplantation. In this project epidemiological and clinical data are combined. A second line of work refers to the role of social factors in the onset and course of breast cancer and cardiovascular diseases. The respective studies are being conducted with clinical populations. A long term-study on breast cancer started in 2002, and the preparations for a 10-year follow-up of patients with congenital heart disease have recently begun. In all these studies clinical and social/ psychological measures were integrated and analyzed within the context of interdisciplinary research groups. Siegfried Geyer is past president of the European Society of Health and Medical Sociology and currently chairman of the German Society of Medical Sociology. 16 | P a g e PROF. JAN F. GUMMERT, M.D., PH.D. Director of the Department for Thoracic and Cardiovascular Surgery Heart and Diabetes Center NRW Ruhr Universität Bochum Bad Oeynhausen, Germany jgummert@hdz-nrw.de Dr. Gummert has been Director of the Department of Cardiothoracic Surgery, Heart and Diabetes Center NRW, Ruhr University of Bochum, Bad Oeynhausen, Germany, since 2009. After studying Medicine and gaining his M.D. at the University of Bonn, where he also completed a General Surgery Internship, Gummert specialized in the field of cardiac surgery at the Universities of Goettingen and Leipzig. After gaining a Ph.D. in 2000, he became Co-Director of the Department of Cardiac Surgery, Heart Center Leipzig, where he remained until 2006. He then moved to Jena to become Director of the Department of Cardiothoracic Surgery at the University Hospital Jena. Prof. Gummert is a member of various eminent societies in his field, including the German Transplantation Society, the International Society of Minimal Invasive Cardiac Surgery and the German Society for Thoracic & Cardiovascular Surgery. PROF. WILFRIED GWINNER, M.D. Department of Nephrology, Internal Medicine Medizinische Hochschule Hannover Hannover gwinner.wilfried@mhhannover.de Dr. Gwinner studied Human Medicine at Hannover Medical School (MHH) until 1987, and was a research fellow in Nephrology until 1990 at MHH, followed by a postgraduate research fellowship at the Departments of Nephrology and Biochemistry/Molecular Biology, University of Florida until 1992. Clinical specialization in Internal Medicine/Nephrology at MHH until 2000, with subsequent positions as Consultant of Internal Medicine and Nephrology and Head of the Emergency Room/Wards. Experimental studies in oxidative stress mechanisms, venia legendi in 2001 and Professorship for Internal Medicine in 2006. Clinical interests focus on Transplantation. Current research interests include biomarker studies and registry analyses on various relevant topics in transplant medicine (graft rejection, bone & mineral disease, graft and patient outcomes), partly in collaboration with German transplant centers (Deutsche Forschungsgemeinschaft) and European Partners (EU Research Programme). PROF. JEROME KASSIRER, M.D. Distinguished Professor, Tufts University School of Medicine Visiting Professor, Stanford University Boston jpkassirer@gmail.com 17 | P a g e Dr. Kassirer is Distinguished Professor at Tufts University School of Medicine and Visiting Professor at Stanford University. He has been at Tufts for 50 years, and served as Vice Chairman of the Department of Medicine for two decades. His research encompassed acid-base balance, medical decision-making, and cognitive science. He has been a Governor and Regent of the American College of Physicians, chair of the American Board of Internal Medicine, and from 1991 to 1999, as Editor-in-Chief of the New England Journal of Medicine. He has received numerous awards and several honorary degrees, and was elected to the Institute of Medicine, the Association of American Physicians, and the American Academy of Arts and Sciences. He has written extensively about clinical cognition, health care, and financial conflict of interest. He is the author of “On The Take: How Medicine’s Complicity with Big Business Can Endanger Your Health” and co-author of “Learning Clinical Reasoning.” PROF. JILL A. MACOSKA, PH.D. Alton J. Brann Endowed Distinguished Professor of Science and Mathematics Professor of Biological Sciences Director, Center for Personalized Cancer Therapy University of Massachusetts Boston Boston Jill.Macoska@umb.edu Dr. Macoska is currently the Alton J. Brann Distinguished Professor in Science and Mathematics, Director of the Center for Personalized Cancer Therapy, and Professor of Biological Sciences at the University of Massachusetts Boston. The Center for Personalized Cancer Therapy is a joint program of the University of Massachusetts Boston and the Dana Farber/Harvard Cancer Center (DF/HCC) to enable the next generation of well-trained biomedical workforce talent and the future leaders of life sciences research in academia and industry. Prior to the University of Massachusetts, Dr. Macoska was Full Professor in the Department of Urology and Programs in Cellular and Molecular Biology, Cancer Biology, and Computational Medicine and Bioinformatics in the University of Michigan School of Medicine. At Michigan she was also Associate Director for the Genitourinary Program in the Comprehensive Cancer Center (20022006), Associate Chair for Research (2003-2008) and Chief of the Laboratory Division (2008-2010) for the Department of Urology, and Director of the Urology Research Training Program (2007-2010). At the National level, Dr. Macoska has served on peer review for several journals and funding agencies and as a strategic participant in several advisory councils and workshops. She is the current President of the Society for Basic Urologic Research (SBUR) and previously served as Co-Chair and Member of the Organizing Committees for the 2010 and 2011 Annual Fall SBUR Symposia, and Chair of the Organizing Committee for the 2012 Annual Symposium. In 2012 she received the Society of Women in Urology/Society for Basic Urologic Research Award for Excellence in Urologic Research. Dr. Macoska has led peer-reviewed and funded research for the past 20 years focused on elucidating the molecular genetic alterations and dysfunctional inter- and intra-cellular signaling mechanisms that promote lower urinary tract pathobiologies. Her current research interests include mesenchymal cell biology, tumor microenvironment, and epithelial mesenchymal transition. PROF. MICHAEL MARSCHOLLEK, M.D., M.SC.,PH.D. Acting director, PLRI Site at Hannover Medical School Peter L. Reichertz Institute for Medical Informatics University of Braunschweig Institute of Technology and Medizinische Hochschule Hannover Hannover Michael.marschollek@plri.de Dr. Marschollek has received his M.D. (Dr. med.) degree from Hannover Medical School in 1999 and has worked as a surgeon and specialist in sports medicine. He received his M.Sc. degree in informatics in 2004 and the doctoral degree in engineering (Dr.-Ing.) from the University of Braunschweig – Institute of Technology in 2009. He is director of the Peter L. Reichertz Institute for Medical Informatics of the University of Braunschweig – Institute of Technology and Hannover Medical School at Hannover Medical School. His recent research interests include: clinical applications of health-enabling technologies, medical data mining and pattern recognition, sensor-based activity analysis/ accelerometry, sensor-enhanced health information systems and decision support systems for exercise rehabilitation. He is founder and head of the International Medical Information Association’s (IMIA) working group ‘Wearable Sensors in Healthcare’. He is executive editor of the ‘Gerontechology’ section of Zeitschrift für Geriatrie und Gerontologie – European Journal of Geriatrics, and on the editorial boards of ‘Methods of Information in Medicine’ and ‘Journal of Medical Systems’. 18 | P a g e PROF. DR. AXEL C. MÜHLBACHER IGM Institut Gesundheitsökonomie und Medizinmanagement Hochschule Neubrandenburg Fachbereich Gesundheit, Pflege, Management Neubrandenburg muehlbacher@hs-nb.de HANS CHRISTOPHE PAPE, M.D., F.A.C.S. Chairman, Department of Orthopaedic Trauma RWTH- Aachen Aachen hpape@ukaachen.de PROF. ROBERT PRICE, PH.D. Prof. em. Biochemistry IALS Board Member King’s College London London Robert.price@kcl.ac.uk 19 | P a g e Dr. Mühlbacher is professor of health economics and health care management at the Hochschule Neubrandenburg. CHPR Senior Research Fellow, Duke Global Health Institute, Duke University. He is director of Gesellschaft für empirische Beratung mbH, Freiburg. Axel Mühlbacher was a 2010-11 Harkness Fellow in Health Care Policy and Practice placed at Duke Clinical Research Institute and Fuqua School of Business, Duke University. In 1996 he graduated from the Eberhard-Karls University, Tübingen, where he studied business administration and economics. In 1996 he was appointed as research fellow at the German Coordinating Agency of Public Health (GCAPH) at AlbertLudwig University, Freiburg. In 1999 he joined the research training group "Demandoriented and cost-effective Health Care - Fundamentals of optimal Allocation" (Graduiertenkolleg) at TU Berlin, HU, FU Berlin with a Scholarship from the German Research Foundation (DFG). In 2001 he graduated with a doctorate in economics and business administration (Dr. rer. oec.) with a thesis on Management and organization of integrated care - an economic analysis of health care delivery networks. Prior to founding the Institute of Health Economics and Health Care Management in 2006, Dr. Mühlbacher was assistant professor at the department of economics and management at Technical University Berlin (2001-2004) and associate professor of economics, health economics and econometrics (C2) at Hochschule Neubrandenburg (2004-2006). His primary area of specialization is on the application of decision analysis and stated preference research in health care management, utility assessment, health technology assessment and outcomes research. Dr. Pape is currently Chairman, Department of Orthopedic Trauma, University of Aachen Medical Center; IALS Vice President for Transatlantic Initiatives; Editor: Spine and Pelvis, Injury Journal; Editor: Patient Safety in Surgery; Editor-in-Chief: Open Access Emergency Medicine. Major awards: German Society of Surgery, 1998, Peter Canizaro award, American Association for the Surgery of Trauma, 1999; Swiss AO Award, 2007, Kappa Delta award, American Association of Orthopaedic Surgeons, 2008. Book editor: Practical procedures in Orthopaedic surgery, Wiley press 2005; Damage control Management, Springer 2008; The polytraumatized patient with fractures, Springer 2011. Board-certified surgeon; Board-certified traumatologist; Reviewer for renowned medical journals; Member of the IALS Development Committee. Guest professorships: University of Alabama (Birmingham), University of Colorado, Denver, McGill University, Montreal. Chief of Trauma and Associate Professor, University of Pittsburgh (2005-09). Degree in Medicine, Hannover Medical School, with specialization in orthopedics, trauma surgery and emergency medicine. Doctorate thesis (1989): Impact of iloprost on the lysosomal membrane of the feline brain (NCH). Postdoctorate thesis (2005): Systemic effects of intramedullary nailing of femoral fractures in severe trauma. 1985/96 BMEP Participant at Vanderbilt University, Nashville. Professor Price is currently Emeritus Professor of Biochemistry in the Diabetes and Nutritional Sciences Division, Faculty of Life Sciences & Medicine, King’s College London and a Director of PPR diagnostics Ltd. He was previously Head of Research and Head of Molecular Life Sciences, Division of Life Sciences. He obtained a PhD and a DSc from the University of Wales and was a Fulbright Fellow at Harvard Medical School. He has published over 250 peer-reviewed papers, books and articles. His principal research interest is the investigation of the underlying mechanisms involved in renal disease. An interest in biomarkers and nephrotoxicity arose from these studies and was central to long term collaboration with five European Laboratories. Current interests include the development of rapid point of care diagnostic tests for disease and infection. PROF. DAN SIMOVICI, PH.D. Department of Computer Science University of Massachusetts Boston Dan.simovici@umb.edu PROF. HILMAR STOLTE, M.D. Univ.Prof.em. & President IALS Medizinische Hochschule Hannover Hannover stolte@lifesciences.net 20 | P a g e Dr. Dan Simovici is a professor of Computer Science at University of Massachusetts Boston and an associate member of Dana-Farber Cancer Institute. His main research interests are in Data Mining and in the algebraic aspects of multiple-valued logic. Dr. Simovici is the author or coauthor of more than 160 research papers and he co-authored several books. His latest book "Mathematical Tools for Data Mining" appeared this year in its second edition at Springer. He is the managing editor of the International Journal for Multiple-Valued Logic and Soft Computing. Dr. Stolte’s medical education was at the Medical Schools of the Universities of Kiel, Goettingen and Cologne, receiving his Doctor’s Degree in Medicine from the University of Goettingen in 1964. From 1974 to 2000 he was University Professor for Internal Medicine and Special Nephrology and Chief of Experimental Nephrology at Hannover Medical School. As author of more than 220 scientific publications, chiefly in the fields of clinical and applied renal physiology, he is currently both University Professor em. at Hannover Medical School and Distinguished Professor of Charité University Medicine at the Humboldt University & Free University of Berlin. His various awards include the Schoeller-Junkmann Award for Research conducted in the area of Endocrinology, and the “Verdienstkreuz am Bande” (Cross of Merit on Ribbon), awarded by the Federal Republic of Germany in 2000. Throughout his working life, from 1968 to 2000, Professor Stolte has managed to acquire research support in Germany (DFG German Research Foundation). He also managed to secure funding from both Europe (CEC/EU, Brussels) and the USA (Buswell Foundation, Buffalo & NIEHS, Raleigh). Professor Stolte has worked in the USA as a Research Associate at the National Institutes of Health, Bethesda, Maryland, as a Visiting Assistant Professor at the State University of New York at Buffalo, N.Y., Departments of Medicine and Physiology, as a Research Associate at the Case Western Reserve University, Cleveland, Ohio, Department of Biology, and – over a period of 30 years – as a Research Associate and Principal Investigator at the M.D.I. Biological Laboratory, Salsbury Cove, Maine. He initiated the non-profit membership organization IALS – International Academy of Life Sciences – whose mission is to promote cutting-edge issues in the Life Sciences through graduate and postgraduate training, as well as feasibility studies and white papers, and has been its President throughout. International Life Sciences Workshops Series: "Decision-Making in Biomedical Science – Meet the Experts " PART 2: Biomarkers, Analysis, and Implementation PARTICIPANTS: This International Workshop is limited to a maximum of 18 to 20 participants in one or more of these categories: Established post-graduates, fellows and clinical scientists who want an overview of data management; Young professors / faculty members from across informatics, with a basic science background and/or field study experience; Young research group leaders in university institutions, industry research laboratories, and extramural scientific government and non-governmental organizations. WORKSHOP DATES: PART 2: Biomarkers, Analysis, & Implementation: 6 March 2015 through 10 March 2015 This workshop is designed for participants to attend both workshops. Part 1 provided a key knowledge foundation, while Part 2 provides applications experience and training. However, participants may attend just one part, if desired. WORKSHOP LOCATION Le Manége Haus der Brandenburgisch-Preußischen Geschichte Am Neuen Markt 9 14467 Potsdam, Germany http://www.hbpg.de/Startseite.html TUITION: Participants attending only Part 2: €1800 per session. IALS University Network Member / BMEP Alumni Discount: If you belong to one of the IALS University Network Members or are one of our BMEP alumni, tuition for Part 2 is €1600. When you register, please note which Member organization you belong to: Medizinische Hochschule, Hannover University of Massachusetts Boston Charité-Universitätsmedizin Berlin Deutsches Herzzentrum Berlin RWTH-Aachen University, Faculty of Medicine, Aachen HDZ NRW Bad Oeynhausen, RuhrUniversität Bochum 21 | P a g e Institute of Experimental Medicine, Dept. of Molecular Genetics, RAMS, St. Petersburg University of Illinois IGPA, UrbanaChampaign BMEP Alumni REGISTRATION: For a registration form, see www.lifesciences.net . To request a registration form, contact IALS.University.Network@gmail.com Registration deadline is January 30, 2015. CERTIFICATE: Participants who complete each Part will receive a certificate of accomplishment from the College of Advancing and Professional Studies, University of Massachusetts Boston; and Faculty of Medicine, RWTH Aachen; on behalf of the overall IALS Life Sciences University Network. ACCOMMODATIONS: Accommodations and travel are participants’ responsibility, and you are free to make your accommodations where you wish. However, for your convenience, we have reduced rates (€94 per night) at the Mercure Hotel Potsdam City. When making your reservation, please inform the hotel you are part of the IALS / UMB Workshop. Mercure Hotel Potsdam City Lange Brucke 14467 Potsdam Tel: +49 331 272 2, http://www.mercure-hotel-potsdam.de/en/ CONTACTS IALS-INTERNATIONAL ACADEMY OF LIFE SCIENCES & EUROPEAN OFFICE UNIVERSITY OF MASSACHUSETTS BOSTON Forum Neuer Markt Am Neuen Markt 6 D-14467 Potsdam T. +49.331.8170-701 UMB@lifesciences.net LAURA L. HAYMAN, PH.D., R.N., FAAN Associate Vice-Provost for Research University of Massachusetts Boston 100 Morrissey Blvd. Boston, MA 02125-3393 laura.hayman@umb.edu MARY J. MCDERMOTT Representative, IALS Life Sciences University Network US/Canada 5932 Baker Avenue Mays Landing, NJ 08330-4026 ials.university.network@gmail.com 22 | P a g e