OPDC Programme - Oxford Parkinson`s Disease Centre

OPDC Programme
0830
Registration
0900
Welcome and Introduction
Dr Richard Wade-Martins · Oxford Parkinson’s Disease Centre
0910
Special Guest
Dr Arthur Roach · Director of Research and Development at Parkinson's UK
0920
Special Guest
Paul Mayhew Archer · Parkinson's UK, Oxford
Progress in Parkinson’s Clinical Research
Chair: Professor Paul Matthews and Professor Howard Federoff
0930
The Oxford Parkinson’s Disease Centre (OPDC) Clinical Cohort
Dr Michele Hu · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical Neurosciences
0950
Parkinson’s and REM sleep behaviour disorder
Dr Michal Rolinski · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical
Neurosciences
1010
SELECTED ABSTRACT A general copper-mediated nucleophilic 18F fluorination of arenes:
application to 6-[18F]fluoro-L-DOPA
Dr Enrico Emer and Professor Véronique Gouverneur · Chemistry Research
Laboratory
1025
Coffee and Posters
Proteomics and Neuropathology in Parkinson’s
Chair: Professor Jeffrey Kordower and Professor Patrik Brundin
1055
Developing Parkinson's proteomic biomarkers: lessons from studies in Alzheimer's
1115
Molecular mechanisms of endosomal trafficking and their translational application in
Parkinson's disease
Professor Simon Lovestone · Oxford Parkinson’s Disease Centre · Department of Physichiatry
Dr George Tofaris · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical
Neurosciences
1135
Selective vulnerability and prion-like propagation in Parkinson’s disease
Dr Laura Parkkinen · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical
Neurosciences
1155
KEYNOTE LECTURE · Cohort studies in Parkinson’s disease: Tracking Parkinson’s
Dr Donald Grosset
Institute of Neurological Sciences, Glasgow; University of Glasgow
1225
Lunch and Posters
Investigating the Cellular and Molecular Biology of Parkinson’s
Chair: Professor Clive Svendsen
1325
Omics and the OPDC: Network approaches to Parkinson’s
Dr Caleb Webber · Oxford Parkinson’s Disease Centre · MRC Functional Genomics Unit,
Department of Physiology, Anatomy and Genetics
1345
Generating iPS cells from the OPDC cohort, and their use for disease
modelling
Dr Sally Cowley · Oxford Parkinson’s Disease Centre · Sir William Dunn School of Pathology
1405
Translating Parkinson's: stem cell-derived patient neurons for target discovery
Dr Richard Wade-Martins · Oxford Parkinson’s Disease Centre · Department of Pysiology,
Anatomy & Genetics
1425
KEYNOTE LECTURE· Parkinson’s disease; considerations from a simple
(organism) perspective
Dr Alex Whitworth
Reader in Neurogenetics, Department of Biomedical Science, The University of Sheffield
1455
Tea and Posters
Molecules to Movement: Improved Animal Models of Parkinson’s
Chair: Professor Marie-Francoise Chesselet
1525
BAC transgenic rodent models of Parkinson’s disease
1545
SELECTED ABSTRACT Bioenergetic and autophagic impairments drive age-dependent
Dr Natalie Connor-Robson · Oxford Parkinson’s Disease Centre · Department of Physiology,
Anatomy & Genetics
neurodegeneration in an α-synuclein overexpression BAC-transgenic mouse model
Dr Brent Ryan · Oxford Parkinson’s Disease Centre · Department of Physiology, Anatomy & Genetics
1600
Intersectional optogenetic tools to explore dopamine neuron heterogeneity in
Parkinson’s disease
Dr Sarah Threlfell · Oxford Parkinson’s Disease Centre · Department of Physiology, Anatomy &
Genetics
1620
Altered encoding of movement by dopamine neurons in early Parkinson’s
1640
KEYNOTE LECTURE· Functional changes of dopamine substantia nigra
Dr Paul Dodson · Oxford Parkinson’s Disease Centre · MRC Anatomical Neuropharmacology Unit
neurons in Parkinson Disease
Professor Jochen Roeper
Neuroscience Centre, Institute for Neurophysiology, Goethe University, Frankfurt
1710
Concluding Remarks from Special Guest
Sally Bromley · Chair, Oxford Branch Parkinson’s UK · Monument Discovery Cohort Participant
1720
Poster Prize Award
1725
Drinks and Posters
1900
Research Day ends