The London Implant Retrieval Centre

 The London Implant Retrieval Centre Contributors Update September 2010
We now have the largest collection of current generation, large diameter metal-on-metal hip replacements
in the world (resurfacing and modular). 93 hospitals have contributed implants, imaging and tissue over the
last 2 years.
Examples of recent dissemination of our results:
350th Royal Society Summer Science exhibition, June & July
2010, The South Bank, London. This was a tremendous success
with over 10,000 public visitors, including a royal visit (see right).
Details of the work presented are available from
www.diamond.ac.uk
Oct 2009 Annual German Orthopaedic Meeting (10,000 medical delegates)
Feb 2010 American Academy of Orthopaedic Surgeons (30,000 medical delegates)
Aug 2010 British Orthopaedic Research Society
Podium presentations at forthcoming meetings
Oct 2010 International Society for Technology in Arthroplasty
Oct 2010 Combined meeting of the Orthopaedic Research Societies
(4 podiums and running the workshop on metal-on-metal hip replacements)
Dec 2010 Radiological Society of North America (60,000 medical delegates);
Feb 2011 American Academy of Orthopaedic Surgeons (30,000 medical delegates):
Scientific Exhibit. Understanding why metal-on-metal hip arthroplasties fail: The
London Implant Retrieval Centre. Hart, Underwood, Cann, Sampson, Mitchell,
Satchithananda, Porter, Cobb, Skinner
Podium: 033. Retrieval analysis of 240 metal-on-metal hip components: stemmed
versus resurfacing designs. Hart, Underwood, Cann, Ilo, Matthies, Porter, MuirheadAllwood, Cobb, Skinner. Tuesday 15th February. 16.12 – 16.18pm
Podium: 067. Clinical and wear analysis of 276 failed large diameter metal-on-metal
hip components. Hart, Underwood, Cann, Ilo, Matthies, Porter, Muirhead-Allwood, Cobb,
Skinner. Wednesday 16th February. 8.48 -8.54am
Podium 068. The Occurrence of Edge Loading in Metal on Metal Hips: Low Clearance
is a New Risk Factor. R J Underwood, A Zografos, A Matthies, K Ilo, P M Cann, F Lali, J
Skinner, A Hart. Wednesday 16th February. 8.54-9.00am
www.imperial.ac.uk/medicine/hipcentre
The London Implant Retrieval Centre Benefits of the LIRC:
1. A process to allow implant manufacturers to respond to concerns regarding the safety of one of its
products.
2. Clinical, laboratory and engineering analysis of failed metal-on-metal hip implants provided to the
manufacturer of that implant.
3. A peer reviewed process of identical and independent analysis of explanted metal-on-metal hip
replacements for each manufacturer.
4. A process for tracking and reviewing the performance of metal-on-metal hips.
5. The involvement of relevant regulatory and professional bodies in our analysis and of our results.
6. Dissemination of findings to the following groups:
Academic: musculoskeletal and bio-materials research scientists ·
Commercial: medical device industries, particularly orthopaedic implant manufacturers
Clinical: orthopaedic surgeons
Regulatory: MHRA
National Health Service
Who are we?
The London Implant Retrieval Centre (LIRC) is funded by the British Orthopaedic Association (BOA). The
LIRC was set up and is run by two consultant orthopaedic surgeons Alister Hart and John Skinner. It is a
joint venture between Imperial College London, the Royal National Orthopaedic Hospital, the British
Orthopaedic Association and 9 orthopaedic companies (JRI, Corin, Mathys, Zimmer, Depuy, Finsbury,
Stryker, Smith & Nephew, Biomet). It has the support of the Medicines and Healthcare Regulatory Agency
(MHRA).
Our coordinator is Gwynneth Lloyd. The mechanical analysis is supervised by Dr Philippa Cann and
performed by Dr Richard Underwood. Our steering committee is Prof Justin Cobb, Sarah Muirhead-Allwood
and Martyn Porter. We are assisted by clinical chemist Dr Barry Sampson and radiologists Dr Adam
Mitchell and Dr Keshthra Satchithananda.
www.imperial.ac.uk/medicine/hipcentre