Bec AR Program(201502 ITBTNTET포함)(20150323 최종본).hwp
Transcription
Bec AR Program(201502 ITBTNTET포함)(20150323 최종본).hwp
BEC.AR Program 2015 4QFDJBMJ[BUJPO$PVSTFJO.BOBHFNFOUPG/FX5FDIOPMPHJFTJO4DJFODFBOE5FDIOPMPHZ *OGPSNBUJPO5FDIOPMPHZ /BOP5FDIOPMPHZ #JP5FDIOPMPHZ &OFSHZ5FDIOPMPHZ "VHVTU_0DUPCFS Table of Contents ᢠ. About Ajou University ························ 3 ᢡ. Introduction to BEC. AR Program ··· 6 ᢢ. Program Details ·································· 11 ᢣ. Program Management ······················ 30 VI. IT, BT, NT, ET ····································· 37 I ABOUT AJOU UNIVERSITY G Introduction to Ajou University Ajou University, established in 1973 under the motto of "Asia's best university for the 21st century", is a leading research university with 10 colleges in Korea. Located in Suwon, about 30km south of Seoul, Ajou has 14,000 students (9,000 undergraduate, 3,500 graduate, and 1,500 in other courses). The strength in Ajou's academic programs and research lies in Engineering, IT, BT, NT, Medical Science, Business and International Studies. Ajou is widely recognized for its innovative international programs and strong support for international students and has collaborative partnership with over 200 universities in 58 countries. There is a wide range of international programs at Ajou including student and faculty exchanges, international summer school, Korean language program, etc. International students are taking courses offered in English by various majors. Today Ajou is welcoming about 750 international students a year. Ajou University’s name bears an ambition to become ‘The best university in Asia in the 21st century when Asia becomes the center of the world ’. Since its foundation, Ajou has pursued the following three virtues as guiding principles: “Respect for Humans”, “Seeking Truth from Fact”, and “One World, One Family.” ٢ Respect for Humans (In-gan-jon-jung) This means high self-esteem with the respect for others. It is the first principle that Ajou pursues through its research, education, and public service. It teaches us to connect ourselves to our neighborhoods, nation and to the world through respect and understanding, regarding a human being not as a tool, but as an ultimate goal or a value. ٢ Seeking Truth from Fact (Sil-sa-gu-si) Seeking truth from fact conveys the meaning that academic results should be useful in practice. It is Ajou’s most fundamental philosophy that seeking truth and academic research must be based on facts and their results should contribute to people’s welfare. ٢ One World, One Family (Se-gye-il-ga) This is a spirit that emphasizes that the entire world should move in harmony. We must break through the small barrier of the Korean Peninsula and advance to the world, and at the same time accept what’s coming from the outside. This is Ajou’s foremost principle in educating the youth. G Facts & Figures A. Colleges & Schools College of Engineering College of Information Technology College of Natural Sciences School of Business Administration College of Humanities College of Social Sciences College of Law School of Medicine College of Nursing College of Pharmacy College of General Education Division of International Studies B. Graduate Schools General Graduate School Graduate School of International Studies Graduate School of Information and Communication Graduate School of Engineering Graduate School of Business Administration Graduate School of Public Affairs Graduate School of Education Graduate School of Information & Communication Technology Graduate School of Transportation & Intelligent Transport Systems Graduate School of Public Health Graduate School of Medicine Graduate School of Law Graduate School of Judicial Affairs Graduate School of Clinical Dentistry Graduate School of IT Convergence C. Ajou Family (2014) Students Program Undergraduate Students Master Course Students Doctor’s Course Students Total No. of Enrollment(2014) 9,988 3,803 504 14,295 No. of Student 12,902 4,115 582 17,599 Others University 337 198 123 658 Hospital 126 232 109 467 Total 463 430 232 1,125 University 116 53 46 215 Hospital 1,755 425 2,180 Total 1,871 478 46 2,395 Faculties Faculty Professors Associate Professors Senior Lecturers Total Staffs Staff Full-time Staff Contract Staff Technical Staff Total Partner Universities Partner Universities and International Organizations Total North America 41 Europe 111 Asia 112 Oceania 5 South America 3 Africa 7 Organization 4 283 institutions in 62 Countries (Bilateral agreement) D. Location of Ajou University Address: Ajou University, 206, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 443-749, Korea. Website: www.ajou.ac.kr Tel: +82-31-219-2114 İ INTRODUCTION TO BEC. AR PROGRAM G Program Name: BEC. AR Program(Specialization Course in Management of New Technologies in Science and Technology) - Information Technology - Nano Technology - Bio Technology - Energy Technology G Education Goal: Contribute to the scientific development Argentine through overseas training of Argentina professionals in areas of strategic importance for the country’s sustainable. G Education Period: From 30th July, 2015 to 31st October, 2015 (3months) G Number of Participants: 40 persons G Qualifications z Be recommended by Argentina Government z Be Professionals in Science & Technology with a Bachelor’s Degree or higher z Have sufficient command of both spoken & written English to take classes conducted entirely in English z Be in good health, both physically and mentally to undergo the program G Program Information The program has 5 compulsory modules for all the students. Module 1 corresponds to Korean Economic Development this module is common and compulsory for all students. It consists of 3 obligatory subjects totaling 60 hours of classes. Module 2 corresponds to Innovation Management in Business and Industry. This module is common and compulsory for all students. It consists of 3 obligatory subjects totaling 60 hours of classes. Module 3 corresponds to New Technology in Science and Engineering. This module is divided into four orientations: Information Technology, Biotechnology, Nanotechnology and Energy Technology. Students must apply to one of the four orientations, which will be taught simultaneously. They can´t take the four orientations all. Each orientation consists of 5 or 6 obligatory subjects totaling 130 hours. Module 4 corresponds to the Korean language, common and compulsory for all students, consists of a compulsory subject with a total of 48 hours of study. Module 5 corresponds to Field Studies, is common and compulsory for all the students. This module consists of three different types of activities with 96 hours of total duration. A. Education Fields Module Module Module Module Module Module 1 2 3 4 5 Education Fields Korean Economic Development Innovation Management in Business and Industry New Technology in Science &Engineering(IT, BT, NT, ET) Korean Language Field Study B. Courses in Modules 1) Module 1: Korean Economic Development Course Title Class Hours A. History and Strategy of Korean Economic Development 20 hours B. Technology Innovation and Global Strategy 20 hours C. Contemporary Korean Society 20 hours 3 Courses(Required) 60 hours 2) Module 2: Innovation Management in Business and Industry Course Title A. Organization Structure & Human Resource Management for Innovation Class Hours B. Innovation and Competitive Strategy of in Service Industry 20 hours C. Supply Chain Management 20 hours 3 Courses(Required) 20 hours 60 hours 3) Module 3: New Technology in Science and Engineering(IT/BT/NT/ET) Classification Information Technology (5 Courses 130Hrs) Bio Technology (5 Courses 130Hrs) Course Title Class Hours A. Ubiquitous security and privacy 30 hours B. Ubiquitous Sensor Networks 30 hours C. Mobile Computing Systems 30 hours D Advanced Software Engineering 30 hours E. Self-Research 10 hours A. New drug development and perspectives: Chemical Drugs 30 hours B. New drug development and perspectives : Biological Drugs 30 hours C. Functional/medical foods 30 hours D. Past and Future of Natural Product and Drug Development 30 hours E. Self-Research 10 hours A. General Introduction of Nanotechnology, Chemistry and Physics of Nanomaterials 30 hours B. Fabrication of Nanomaterials; Zero to Three Dimension Nanostructure Nano Technology (5 Courses C. Characterization and Manipulation of 130Hrs) Nanomaterials Energy Technology (6 Courses 130Hrs) 30 hours 30 hours D. Applications of Nanotechnology 30 hours E. Self-Research 10 hours A. Energy Economics/Policy 15 hours B. Energy Conversion Technology I [Catalysis & Clean Energy] 30 hours C. Energy Conversion Technology II [Solar Cells & Sensors] 30 hours D. Energy Storage Devices and Technology 30 hours E. Prospects for the Decentralized Energy Supplying System of New & Renewable Energy 15 hours F. Self-Research 10 hours Choose 1 field(IT/BT/NT/ET) – 5 or 6 Courses 130 hours 4) Module 4: Korean Language Classification Class Hours Korean Language 1 hour per day 48 hours 5) Module 5: Field Study Classification Special Lecture (3 Times) Industrial Site Visit (3 Times) Field Trip (3 Times) Field Study Activities Class Hours Embassy of Argentina 2 hours Alternative Energy and Green Growth 2 hours Ministry of Foreign Affairs 2 hours Jeju Island: - JTP(Jeju Techno Park),Jeju Entertainment Industry 27hours(9hr*3days) Pohang-Ulsan-Busan- POSCO(Pohang Steel Company)- Hyundai Motors Co 27hours(9hr*3days) Geoje –Yeosu- DSME(Daewoo Shipbuilding & Marine Engineering)Lotte Chemical 27hours(9hr*3days) KEPCO 3 hours Korea Institute of Energy Research(KIER) 3 hours KEPCO Research Institute Electronics and Telecommunication Research Institute 3 hours National Nanofeb Center 3hours Ajou University Medical Center 3hours 96 hours 3hours For Energy Technology For information Technology and Nano Technology C. Education Hours per person: Total 394 hours Module Module Module Module Module Module Total 1 2 3 4 5 Education Hours / person 60 hours (4 Credits) 60 hours (4 Credits) 130 hours (8 Credits) 48 hours (3 Credits) 96 hours (6 Credits) 394 hours (Equal to 8 Subjects, 25 Credits) st 394 class hours is same as 1 year classes of Master’s program D. Class Hours a Week 1) Monday to Thursday: Lecture (Module 1, 2, 3) Class Class Time 1st 09:00 ~ 10:15 (75 minutes) 2nd 10:30 ~ 11:45 (75 minutes) Lunch Time 12:00 ~ 13:30 3rd 4th 5th Aug. 1~Aug. 30 Sept. 1~Sept. 31 Oct. 1~Oct. 31 Module 1 Module 2 Module 2 Module 3 Module 3 Lunch Time (90 minutes) 13:30 ~ 14:20 (50 minutes) Module 4 (Korean Language) 14:30 ~ 15:20 (50 minutes) 15:30 ~ 16:20 Module 1 Module 2 Module 2 Module 3 Module 3 (50 minutes) 2) Friday: Special Lecture, Industrial Site Visit, Field Trip 3) Saturday: Industrial Site Visit 4) Sunday: Rest E. Class Period in each Module Class Period: 3 Months(12 weeks) Module 1: 4 weeks, 20hours a Course, 5hours a day, 20hours a week Module 2: 4 weeks, 20hours a Course, 5hours a day, 20hours a week Module 3: 6 weeks, 30hours a Course, 5hours a day, 20hours a week Module 4: 12weeks, 48hours, 1hour a day, 4hours a week Module 5 ّ Special Lecture: 3 times(Embassy of Argentina, Alternative Energy and Green Growth, Ministry of Trade, Industry and Energy) ّ Industrial Site Visit: 2 nights 3 days, 3 times(Jeju Island, Pohang–Ulsan–Busan, Geoje-Yeosu) ّ Field Trip: 3times T T T T T KEPCO Korea Institute of Energy Research(KIER) Electronics and Telecommunication Research Institute National Nanofeb Center Ajou University Medical Center ı PROGRAM DETAILS G Curriculum A. Module 1: Korean Economic Development ٢Course A: History and Strategy of Korean Economic Development This course introduces the History of Korean Economic development, and studies the enablers of the fast-growing development. In the last 50 years since the 1st 5-year economic development plan in 1962, Korean government used different development strategies depending on the global environment. Students will learn history and strategy of Korean economic development. ٢Course B: Technology Innovation in Korean Industry One of the most successful companies in Korea are Samsung Electronics, Hyundai Motors, KEPCO(Korea Electronic Power Corporation). This course shows that how these companies achieve and maintain technology innovation, and what kinds of global strategies are applied in order to keep competitiveness in severe global competition. ٢Course C: Contemporary Korean Society This course will discuss various aspects of Korean contemporary society, grouped under the headings: Civil society; Demography/class/labor; Democratization and social movements; Education and Korean society; Gender and Korean society; and Religion in Korean society. B. Module 2: Innovation Management in Business and Industry ٢Course A: Organization Structure & Human Resource Management for Innovation Organization structure and human resource management are key factors to successful innovation. Students will learn basic theories of organization & human resource management, and will study various cases of organization restructuring and types of leadership in order to achieve highly successful innovation. ٢Course B: Innovation and Competitive Strategy of in Service Industry This course introduces excellent cases among highly successful Service companies that are globally recognized for their innovations and competitive business strategies. Students will engage in the discussion followed by the analysis of companies' success factors. Prior to the discussion, students will be acquainted with the companies' market leading technologies and their continuous quality improvement efforts. ٢Course C: Supply Chain Management Course Outline: We learn important issues in manufacturing and distribution industry such as purchasing, production, inventory, sales, and logistics from the SCM perspective which is based on partnership and information sharing between partner companies in the same supply chain. Design, operation, and evaluation of the supply chain and strategies to successfully implement SCM will be taught. C. Module 3: New Technology in Science and Engineering (Participants should choose 1 field among IT, BT, NT, ET)\ 1) Information Technology (IT) IT Program is basically designed for those who work at industries. IT Program provides state of art courses, lab practices and field trips. Graduate level courses consist of “Security and Privacy”, “Software Engineering”, “Sensor Network” and “Mobile Computing Systems”. Practice hours are given to individual students and TA’s will guide students to solve problems. Students may have three field trips, one huge company such as Samsung or LG electronics, one relatively new big company such as Naver or Naver Entertainment, one small venture company such as QRAM. Students may enjoy Lab tours and may attend various electronic show or conferences. You will meet faculties of computer engineering department of Ajou University who are well recognized by not only in Korea but also in the world. Those who successfully finish IT program might apply for their Ph.D degree at Ajou University. G Course A: Ubiquitous Security and Privacy In this course, initially the factors that threaten security and privacy of invisible covert ubiquitous computing services are introduced. Based on understanding the factors, you can learn the knowledge about how to resolve them in ubiquitous computing environment where requested services for users should be provided anytime and anywhere. For the ubiquitous computing security and privacy, it is important to know how to take advantage of the existing technologies in the field of intrusion tolerant systems. For privacy, you can learn the methodologies of learning models for autonomous and collaborative computing in this course. G Course B: Ubiquitous sensor network (Ubiquitous Sensor Networks) This course initially provides the concepts and the characteristics of ubiquitous sensor networks for basic knowledge about sensor networks. Based on them, you can learn wireless communication which is one of the most critical topics in sensor networks. In addition, energy management, data collection, tracking and security as important topics in wireless sensor networks are covered. G Course C: Mobile Computing Systems Considering that after the overall structure of the mobile computing research, the characteristics and constraints of the mobile computing environment, according to the components of the research, case studies and commercial products. Moving Ad hoc networks, wireless TCP, a variety of wireless networking and data & location management, hand-off technologies such as mobile computing in the environment of the operating system / application / algorithm, energy management, etc. are included. G Course D: Advanced Software Engineering (Advanced Software Engineering) This course contains concepts, methodologies, and techniques regarding existing software engineering. Also, the evaluation and the analysis of existing software engineering techniques are covered. As a high-level software engineering course, a newly emerging object-oriented software engineering (OOSE), systems engineering, a new concept of component-based software engineering (Component-based SE) and architecture-based software engineering (Architecture-based SE) are provided in this course. G Course E: Self Research Planning self-research project to visit some research institute, Related Company, or co-research program with Korean company. 2) Bio Technology (BT) Biotechnology—the interface between biology and technology—is a field of study that has provided the underlying concepts and tools for a worldwide industry that has greatly benefited medicine, agriculture, the environment, and so on. To someone who is not formally trained as a biologist, the tools, the goals, and the strategies behind the inner workings of biotechnology can be difficult to comprehend and appreciate. This course is for the non-biologist or new-comer biologist who wants to gain a working knowledge of the basic science and technology behind the industry including pharmaceutics. For example, why all the talk about human microbiota? Why is there so much attention on stem cells or antibodies? This is a somewhat interactive course that teaches the fundamentals of biology and medicine as it relates to biotechnology for a non-biologist and/or new-comer biologist who is curious about the fascinating fields, and/or needs to understand it for professional expansions. ٢Course A: New Drug Development and Perspectives-Chemical Drugs Pharmaceutical training and education for new drug research and development will be provided based on basic sciences, clinical information and patient unmet needs from big data. This module is not only to develop various new drugs in niche and global market but also to contribute the pharmaceutical education of new human resources for innovative new drug research & development. Various pharmaceutical sciences and technology will be covered, including statistics for pharmacy, pharmacogenomics for personalized medicines, drug delivery system, drug formulation, clinical investigation and regulatory affairs such as abbreviated investigational new drug development process and recent FDA guide lines. ٢Course B: New drug development and perspectives: Biological Drugs Pharmaceutical training and education for new biological drug research and development will be provided based on genetics and biotechnology. This module is mainly to develop the new biomarker and therapeutic targets for rare and incurable disease, biotechnology for manufacturing and modulating biological drugs and contribute the pharmaceutical education of new human resources for biological drug development. Various pharmaceutical sciences and technology will be covered, including statistics for biological drugs, pharmacogenomics for personalization, clinical investigation, regulatory affairs and FDA guide line for biological drugs. ٢Course C: New drug development and perspectives Module for functional/medical Foods Accumulating evidences indicate that the incidence of allergies and the lifestyle metabolic diseases of cancer, coronary heart disease and diabetes have recently been increasing significantly, and that a strong linkage exists between occurrences of these diseases and dietary habits. The course provide rationale of clarifying food components that contribute to the prevention or alleviation of these diseases or that are related to the onset of these diseases, and of developing foods with nutraceutical functions and eliminating hazardous components from food products. 9 Developing genetic and breeding technologies for qualitative and quantitative improvement of useful functional components and for the elimination of anti-functional components of foods through selective breeding and other biotechnologies related to production processes of food resources 9 Cultivation technologies for newly created plant species. 9 Quantitative techniques for analysis of functional components that prevent lifestyle diseases, to search for and make effective use of food resources with high concentrations of functional components, and to establish technologies for preserving and enhancing the bioactivities of foods during storage and processing. 9 Beneficial microorganisms, immunoregulatory substances, anti-tumor compounds and other substances that contribute to maintaining good human health, and to characterize those substances microbiologically and chemically. 9 The status of functional food development and any problems associated with their production, to establish technologies for overcoming those problems, and to solve patenting and other associated legal issues. ٢Course D: New Drug Development and Perspectives Module for Past and Future of Natural product and Drug Development We provide the background for drug development from natural resources and the ongoing attempts overcoming the limitation of the phytochemical approaches. Oriental medicine in Korea and Asian countries including China and Japan has a long history, but still has a potential for drug development even though there are huddles for further advancement. However, untapped biological resources, “smart screening” methods, robotic separation with structural analysis, metabolic engineering, and synthetic biology offer exciting technologies for new natural product drug discovery. Advances in rapid genetic sequencing, coupled with manipulation of biosynthetic pathways, may provide a vast resource for the future discovery of pharmaceutical agents. Our program encompasses all aspects of natural products research, biosynthesis, chemical synthesis, assay development, screening and target identification, as well as drug development. 9 'LVFRYHU\ (biological resources) 9 'HYHORSPHQW (Smart screening methods, Robotic separation with structural analysis) 9 0LFURELDO *HQRPLFV 9 1XWUDFHXWLFDOV DQG &RPSOHPHQWDU\ $OWHUQDWLYH 0HGLFLQH 9 Metabolic engineering or synthetic biology 9 Promotion of collaborative research with industry 9 Maintenance and novel use of compound libraries ٢Course E: Self Research Planning self-research project to visit some research institute, Related Company, or co-research program with Korean company. 3) Nano Technology (NT) Nanotechnology is the popular term for the construction and utilization of functional structures with at least one characteristic dimension measured in nanometers. Such materials and systems can be rationally designed to exhibit novel and significantly improved physical, chemical, and biological properties, phenomena, and processes because of their size. When characteristic structural features are intermediate in extent between isolated atoms and bulk materials, in the range of about 10-9 to 10-7 m (1 to 100 nm), the objects often display physical attributes substantially different from those displayed by either atoms or bulk materials. Properties of matter at the nanoscale are not necessarily predictable from those observed at larger scales. Important changes in behavior are caused not only by continuous modification of characteristics with diminishing size, but also by the emergence of totally new phenomena. Once it is possible to control feature size and shape, it is also possible to enhance material properties and device functions beyond what are already established. Rational fabrication, integration, and characterization of nanoscale materials and devices herald a revolutionary age for science and technology, provided we can discover and fully utilize their underlying principles. By its nature, the Nanotechnology is an interdisciplinary field, building on latest progress especially in Physics, Chemistry, Biology, and Engineering. The ability of cross-disciplinary communication is absolutely crucial to achieve progress in the field. The objective of this class is to emphasize the basic understanding of the physical phenomena on the nanometer scale and to foster the ability of participants to communicate basic insights in Nanotechnology to scientists in other disciplines. Nanotechnology class will be divided by four areas as follow. Classes for each area are composed with theoretical lectures in the classroom and experiment works in laboratory. Course A: General Introduction of Nanotechnology, Chemistry and Physics of Nanomaterials Nanoscience and nanotechnology are multi-disciplinary engineering field, involving physics, chemistry, materials science, and mechanical, electrical and chemical engineering. Generally, nanotechnology refers to the fabrication, study and manipulation of structure/material having size in the range of 1 to 100 nm. New chemical and physical properties appeared when materials are approaches in nanometer scale will be discussed along with origin of such distinctive properties. Course B: Fabrication of Nanomaterials; Zero to Three Dimension Nanostructure Fabrication of nanomaterials or nanostructure is generally done by top down, bottom-up and self-assembly as done in nature. Each technique will be discussed and actual synthesis of a few materials will be done in laboratories. Fabrication of nanomaterials based on the dimensions of their structural elements will be discussed as follow; zero-dimensional (quantum dot, gold nanoparticle, dendrimers), one-dimensional (nanowire, nanorod, carbon nanotubes), two-dimensional (monolayer thin film) and three-dimensional (DNA helical structure) nanomaterials by using reduction process, electrochemical deposition, chemical vapour deposition and Langmuir-Blodgett technique or self-assembly. Course C: Characterization and Manipulation of Nanomaterials Characterization and Manipulation of Nanomaterials is performed at atomic scale. Some characterization methods are used to study the sizes, shapes, and morphology of the nanomaterial. Besides surface properties, another important aspect such as mechanism of interaction, electrical, strength, mechanical properties and conductivity are also important to understand. Equipment such as scanning probe microscope (AFM and STM) and electron microscope (SEM and TEM) will be discussed in terms of their definition, classification, operation principle and manipulation at the atomic structure. Optical spectroscopic methods also will be introduced for characterization tools of nanomaterials. Course D: Applications of Nanotechnology Numerous applications of Nanotechnology already have been demonstrated both in purely scientific researches and in commercial productions such as in the medicine as drug delivery and tissue engineering, in information and communication area such as display, optoelectronic devices, semiconductor devices and in consumer goods such as cosmetics, antimicrobial toys, sports and household. Those typical and important applications will be introduced along with key technological bottlenecks needed to be addressed. Course E: Self Research Planning self-research project to visit some research institute, Related Company, or co-research program with Korean company. 4) Energy Technology (ET) Energy has had a significant influence not only on living standards in a society but also upon national competitiveness and security. No one can deny the fact that we should prepare for "energy" for next generations because much more attention and emphasis will be putting on energy in the coming future. Energy technology is an interdisciplinary engineering science dealing with the efficient, safe, environmentally friendly and economical extraction, conversion, transportation, storage and use of energy. It is aiming at yielding high efficiency while minimizing side effects on humans, nature and the environment. More specifically, energy technology covers all technical aspects of energy process engineering from different angles, e.g., new concepts of energy generation and conversion, design, operation, control, and optimization of processes for energy generation (e.g., carbon capture) and conversion of energy carriers, improvement of existing processes, combination of single components to systems for energy generation, design of systems for energy storage, production processes of fuels, e. g., hydrogen, electricity, petroleum, bio-based fuels, concepts and design of devices for energy distribution, energy planning, energy management, energy economics and policy. Because of the diversity of energy technology ranging from social studies to advanced technologies, it is quite difficult to find a suitable institute which is able to provide the education program covering all aspects of energy technology. However, you can find an answer at Ajou University. The Department of Energy Systems Research at Ajou University was founded in 1988 as the first graduate program specializing in energy-related education and research in Korea. From then, this program has earned its fame in the energy technology area and now been selected as the recipient of the BK21 Plus program supported by the Korean Government. In this program, we adopt a highly multidisciplinary approach, in which close collaborations among researchers in different disciplines are strongly encouraged and students are educated so that they have broad perspectives on whole energy systems as well as a knowledge of a specific technology. We concentrate on four research areas: energy conversion technology, energy efficiency, energy storage technology, and energy economy and policy-making. Based on this experience, we can offer a unique, high-quality curriculum covering all aspects of energy technology including basic science, engineering and social science to students and trainees. This Energy Technology Program will give you an opportunity to learn the up-to-date information as well as the basic principles on various energy subjects from the renowned experts in his/her specific area. ٢Course A: Energy Economics/Policy Analysis of Energy Systems, Crisis Management, Economic Evaluation of New & Renewable Energy, Energy Model & Analysis of Technology Policy for Future Climate Change Response Efficiency Improvement and Analysis of Energy Plants ٢Course B: Energy Conversion Technology I [Catalysis & Clean Energy] Greenhouse Gas Reduction, High Efficient Energy Sources, Develop Alternative Energy Sources, High Efficient CO2 Collection Process, High Performance Catalyst-based Energy Conversion Process ٢Course C: Energy Conversion Technology II [Solar Cells & Sensors] Highly Efficient Solar Cell Materials Development, Materials and Devices Characterization Technology, Semiconductor & Inorganic Solar Cells, Fuel Cell Electric Automobiles & Hydrogen Sensor ٢Course D: Energy Storage Devices and Technology High-Power High-Energy Density Lithium Secondary Batteries, Next Generation Batteries for Electric Vehicles (EV), Ultimate Electrochemical Energy Storage Technology for EV Non-lithium Rechargeable Batteries, Supercapacitors, Development of Energy Systems for Eco-friendly Future Transportation ٢ Course E: Prospects for the Decentralized Energy Supplying System of New & Renewable Energy Energy Efficiency/Clarification, Maximizing Energy Storage and Efficiency, Policy and Development on Smart Grid Energy Technology ٢Course F: Self Research Planning self-research project to visit some research institute, Related Company, or co-research program with Korean company. D. Module 4: Korean Language Developing skills of speaking, listening, reading and writing in a balanced and coordinated manner Learner Centered approach: Class discussions and other study-activities involving students’ active participation. Level: Beginning Korean Language I E. Module 5: Field Study Special Lecture(3times) Embassy of Argentina Alternative Energy and Green Growth Ministry of Foreign Affairs Industrial Site Visit(2nights&3days, 3times) G Jeju Island a) JejuTechnopark (http://www.jejutp.or.kr/) JejuTechnopark is a non-profit organization subsidized by MOCIE(Ministry of Commerce, Industry and Energy) and Jeju provincial Government. Its mission is to develop and foster competitive future industries proper to jeju through the renovation of knowledge, information and technology, in preparation of the 21th century knowledge-based industry society. - Jeju Bio Science Park Jeju Regional Innovation Agency Jeju Bio-Development Industry Center b) Jeju Entertainment Industry (JejuJungmun Resort Complex) Located in the city of Seogwipo on Jejuisland, Jungmun resort is blessed with beautiful natural scenery and warm weather. With numerous entertainment facilities, this high-class tourism resort is popular with domestic and foreign travelers throughout all the four seasons. There are numerous sight-seeing destinations within easy reach of the resort, and it is only thirty minutes from Jeju airport. With the spectacular Mt. Hallasan to the north and the deep blue sea to the south, visitors to Jungmun resort will find it difficult to leave. Jungmun resort is the most famous resort in Jeju Island, and it's top quality facilities rank it among the world's best tourism complexes. Students would get an idea how to make the most popular tourist village combined natural resources and the technology. G Pohang – Ulsan - Busan P POSCO (http://www.posco.co.kr) POSCO has in 1968.As Operating a some 21.24 been the most competitive steel company since its establishment a world-class company, it continues to grow and evolve. total of five hot-strip mills and one mini-mill, POSCO produces million tons of hot rolled sheet annually, of which 9.35 million tons are delivered to customers in the form of finished products for use in automobiles, steel structures, steel pipe, home appliances and a variety of other products. A portion of the hot-rolled sheet output is further processed into value-added products such as cold-rolled products and electrical sheet. P Hyundai Motors (http://www.hyundai-motor.com) Hyundai Motors was established in December 1967. In the early 1980's, fueled by rapid economic growth, Hyundai invested in a major expansion of its Ulsan plant, making a transition from low-volume to high-volume manufacturing. During the late 1980's, the company prepared for the more intense competition that the 1990's would bring. Hyundai Motor Company endured a difficult year in 1998, as domestic sales sharply declined. It was also a period of company-wide and industry-wide restructuring. The acquisition of Kia/Asia Motors will allow Hyundai Motors to achieve the economics of scale needed to compete in the global market. P Busan BEXCO (Busan Exhibition and Convention Center)(http://www.bexco.co.kr) BEXCO has been selected as the venue for the 2005 APEC summit, a gala event that will host representatives from 21 Asia-Pacific countries to discuss regional peace and co-prosperity. BEXCO will host a series of 2005 APEC summit meetings November 14-21, 2005, including the initial summit, the ministerial meeting, the high-ranking meeting, and bilateral meetings between summits. BEXCO holds exhibition and conferences where participants can seek out business opportunities within diverse areas, such as logistics, port-related matters, investment and purchasing. Other related events and business meetings can be held at nearby Haeundae Beach, a world-class resort area within 10 minutes from BEXCO. Past events included the 2002 FIFA World Cup final drawing and the 2002 Busan Asian Games. G Geoje-Yeosu P DSME(Daewoo Shipbuilding and Marine Engineering)(http://www.dsme.co.kr) Started in 1973 at Okpo Bay, Geoje Island, located on the southeastern tip of the Korean Peninsula, the shipyard of DSME was completed in 1981. DSME has since grown into the world's premium shipbuilding and offshore contractor who is specialized in building various vessels, offshore platforms, drilling rigs, FPSO/FPUs, submarines, and destroyers. The shipyard which spans an area of 4.3 million meters squared encompasses the world's largest dock with a million-ton capacity and is optimized for building high-tech motor vessels using cutting-edge equipment, including a 900-ton goliath crane. DSME manufactures high-quality products based on its vast IT expertise, well-managed shipbuilding technologies, superb fixed-platform construction capacities, large-scale project management destroyer construction technologies. know-how, and submarine/ P GS Caltex (http://www.gscaltex.com) Since its establishment in 1967 as the first private oil company in Korea, GS Caltex has always been at the heart of the energy industry. For the past half century, we’ve dedicated ourselves to offering clean energy to enrich people’s lives and providing convenient and easily-accessible energy services for the customers. GS Caltex is the most competitive energy company in Korea who persistently strives to become a leader in the global energy industry. Powered by the state-of-the-art technology and the success of our core businesses, including petroleum, petrochemical, base oil and lubricants, GS Caltex currently exports petroleum and other petroleum-based products to 20 nations worldwide. Field Trip(3times) G ETRI (Electronics and Telecommunication Research Institute) (http://www.etri.re.kr/eng/main/index.etri) Since its foundation in 1976, ETRI, a global ICT research institute, has been making its immense effort to provide Korea a remarkable growth in the field of ICT industry. ETRI delivers Korea as one of the top ICT nations in the World, by unceasingly developing world’s first and best technologies. Korea, the wasteland of Science and Technology, became ICT leading nation through indomitable will and challenging spirit. In the 1980s, one-phone-per -house which brought significant changes to the everyday lives of Koreans was realized by the development of TDX; Time Division Exchange, fully digital electronic switching system. Korea stated to dominate the world’s semiconductor industry by its development of 4M DRAM successfully. During 1990s ETRI once again astonished world by commercializing CDMA for the very first time in the world. In 2000s ETRI developed Terrestrial DMB, WiBro, and 4G LTE Advanced which became the foundation of Mobile Communication. Recently, as a national ICT leader, ETRI is performing ‘communication’ and ‘convergence’ by developing SAN Technology(cutting-edge ICT technology converging with shipbuilding), Korean to English world-class portable automatic interpretation technology, and development of adjustable display technologies, such as transparent display. ٢National Nanofab Center (http://www.nnfc.com/eng/index.jsp ) Since its foundation in 2001 under the Nanotechnology Development Promotion Act, followed by its launch as an adjunct institute of KAIST in May 2004, the National Nano Fab Center(NNFC) has been striving to establish cutting edge nano equipment and facilities, and to provide processing services. Having achieved remarkable growth annually, NNFC boasts a foundation for stable operation, which is has secured over the years. NNFC will develop technologies with competitive strength in order to secure a basis for independent by commercializing research outcomes while building capacity for commercialization. ٢Korea Research Institute of Bio Science and Bio Technology (http://www.kribb.re.kr/eng/) KRIBB is the only government research institute dedicated to biotechnology research across a broad span of expertise, from basic studies for the fundamental understanding of life pheonomena to applied studies such as new drug discovery, novel biomaterials, integrated biotechnology, and bio information. ٢The Korea Institute of Energy Research (http://www.kier.re.kr/eng/) Since the founding in 1977, the Korea Institute of Energy Research(KIER) has had focused on energy technology R&D which is closely related with our living standards and national security while overcoming the challenges we have faced as a resource poor country. KIER's R&D areas include improving efficiency and securing environmentfriendly way in use of limited conventional energy resources such as oil, coal as well as natural gas and exploring new energy sources such as solar, wind and water as well as its commercialization. The KIER also strives towards technology transfer which can be reflected in successful commercialization of our remarkable R&D outcomes by means of industrialization of excellent intellectual property rights, enlarging its R&D activity in bottleneck technology based on small and medium sized enterprises, and communicating actively with markets through "1 researcher to 1 enterprise" technique guidance. ٢Ajou Univeristy Medical Center (http://www.ajoumc.or.kr/) The aim of Ajou University Medical Center's 16 institutes is to facilitate education and medical care through research. Thanks to its advanced research facilities and professional research team, it is well equipped to conduct quality creative research. In addition, the Center's Research Support offers a comprehensive and efficient system for research administration. Ajou University Medical Center is advancing the field of medicine through its participation in the cell transformation and restoration project of BK21's Phase 2 as well as numerous other research themes and projects conducted in collaboration with clinical sites. Our specialized research institutes, such as the Brain Research Center, Neurosciences Technology Research Institute, and Center for Cell Therapy help enhance the quality of medical care by bringing the outcomes of basic science research to clinical sites. They are also garnering an international reputation through innovative achievements in developing cartilage growth drugs and brain-disorder dementia drugs. Also ranked high in terms of research funding and number of theses per professor, the faculty of Ajou University Medical Center are increasing their international competitiveness through their continued research achievements. ٢ KEPCO (Korea Electic Power Corporation) (http://cyber.kepco.co.kr/kepco/EN/main.do) Korea Electric Power Corporation (KEPCO) was founded with the objective to facilitate the development of electric power supply in Korea, meet the country's power supply and demands needs, and contribute to the national economy in accordance with the Korea Electric Power Corporation Act. KEPCO is classified as a market-oriented public corporation under the Act on the Management of Public Institutions. KEPCO's areas of business are based on the aforementioned objectives and include the development of electric power resources, electric power generation, transmission, transformation, and distribution, as well as related marketing, research, technological development, overseas business, investment, corporate social responsibility and use of its property. G Program Schedule ٢ IT/NT - August 2015 (IT/NT) Day 1st class 2nd class 3rd class 4th class 5th class 29.July Wed Arrival, Checking in Accommodation 30 Thu 31 Fri 1.Aug Sat City Tour, Shopping 2 Sun Off 3 Mon M1(Course A) M4 M1(Course A) 4 Tue M1(Course B) M4 M1(Course B) 5 Wed M1(Course C) M4 M1(Course C) 6 Thu M2(Course A) M4 M2(Course A) 7 Fri M5(Field Trip 1) 8 Sat Off 9 Sun Off 10 Mon M1(Course A) M4 M1(Course A) 11 Tue M1(Course B) M4 M1(Course B) M1(Course C) M2(Course A) Orientation, Registration, Health checkup Immigration Bank Account Welcoming ceremony, Campus Tour 12 Wed M1(Course C) M4 13 Thu M2(Course A) M4 14 Fri Independence Day 15 Sat Off 16 Sun Off 17 Mon M1(Course A) M4 M1(Course A) 18 Tue M1(Course B) M4 M1(Course B) 19 Wed M1(Course C) M4 M1(Course C) 20 Thu M2(Course A) M4 M2(Course A) 21 Fri M5(Special Lecture 1) 22 Sat Off 23 Sun Off 24 Mon M1(Course A) M4 M1(Course A/Exam) M1(Course B/Exam) M1(Course C/Exam) 25 Tue M1(Course B) M4 26 Wed M1(Course C) M4 27 Thu 28 Fri 29 Sat M5(Industrial Site Visit 1) 1st class: 09:00~10:15(75min), 2nd class: 10:30~11:45(75min), 3rd class: 13:30~14:20(50min), 4th class: 14:30~15:20(50min), 5th class: 15:30~16:20(50min) Remark - September 2015 (IT/NT) Day 1st class 2nd class 3rd class 4th class 5th class 30 Sun Off 31.Aug Mon M2(Course B) M4 M2(Course B) 1.Sep Tue M2(Course C) M4 M2(Course C) 2 Wed 3 Thu M2(Course A) M4 M2(Course A) 4 Fri M2(Course C) M4 M2(Course C) 5 Sat Off 6 Sun Off 7 Mon M2(Course B) M4 M2(Course B) 8 Tue M2(Course C) M4 M2(Course C) 9 Wed M2(Course B) M4 M2(Course B) 10 Thu 11 Fri 12 Sat Off 13 Sun Off 14 Mon M3(Course C) M4 M3(Course C) 15 Tue M3(Course D) M4 M3(Course D) 16 Wed M2(Course B) M4 M2(Course B) 17 Thu 18 Fri 19 Sat 20 Sun 21 Mon M3(Course C) M4 M3(Course A) 22 Tue M3(Course D) M4 M3(Course B) 23 Wed M3(Course A) M4 M3(Course A) 24 Thu M3(Course B) M4 M3(Course B) 25 Fri 26 Sat 27 Sun 28 Mon Self-Research M5(Field Trip 2) M2(Course C) M4 M2(Course C) M5(Industrial Site Visit 1) Off M5(Special Lecture 2) Thanksgiving Holiday 1st class: 09:00~10:15(75min), 2nd class: 10:30~11:45(75min), 3rd class: 13:30~14:20(50min), 4th class: 14:30~15:20(50min), 5th class: 15:30~16:20(50min) Remark - October 2015 (IT/NT) Day 1st class 2nd class 3rd class 4th class 5th class 29 Tue Thanksgiving Holiday 30.Sep Wed M3(Course A) M4 M3(Course A) 1.Oct Thu M3(Course B) M4 M3(Course B) 2 Fri M5(Special Lecture 3) 3 Sat Off 4 Sun Off 5 Mon M3(Course C) M4 M3(Course C) 6 Tue M3(Course D) M4 M3(Course D) 7 Wed M3(Course A) M4 M3(Course A) 8 Thu M3(Course B) M4 M3(Course B) 9 Fri Self-Research 10 Sat Off 11 Sun Off 12 Mon M3(Course C) M4 M3(Course C) 13 Thu M3(Course D) M4 M3(Course D) 14 Wed M3(Course A) M4 M3(Course A) 15 Thu M3(Course B) M4 M3(Course B) 16 Fri M5(Field Trip 3) 17 Sat Off 18 Sun Off 19 Mon M3(Course C) M4 M3(Course C) 20 Tue M3(Course D) M4 M3(Course D) 21 Wed M3(Course A) M4 M3(Course A) 22 Thu M3(Course B) M4 M3(Course B) 23 Fri 24 Sat 25 Sun 26 Mon M5(Industrial Site Visit 3) M3(Course C) M4 M3(Course C) M3(Course D) 27 Tue M3(Course D) M4 28 Wed M3(Course A) M4 M3(Course A) 29 Thu M3(Course B) M4 M3(Course B) 30 Fri Commencement, 31.Oct Sat Preparing to Leave , Departure Farewell Party 1st class: 09:00~10:15(75min), 2nd class: 10:30~11:45(75min), 3rd class: 13:30~14:20(50min), 4th class: 14:30~15:20(50min), 5th class: 15:30~16:20(50min) Remark ╖ BT/ET - August 2015 (BT/ET) Day 1st class 2nd class 3rd class 4th class 5th class 29.July Wed Arrival, Checking in Accommodation 30 Thu 31 Fri 1.Aug Sat City Tour, Shopping 2 Sun Off 3 Mon M1(Course A) M4 M1(Course A) 4 Tue M1(Course B) M4 M1(Course B) 5 Wed M1(Course C) M4 M1(Course C) 6 Thu M2(Course A) M4 M2(Course A) 7 Fri M5(Field Trip 1) 8 Sat Off 9 Sun Off 10 Mon M1(Course A) M4 M1(Course A) 11 Tue M1(Course B) M4 M1(Course B) 12 Wed M1(Course C) M4 M1(Course C) 13 Thu M2(Course A) M4 M2(Course A) 14 Fri Independence Day 15 Sat Off 16 Sun Off 17 Mon M1(Course A) M4 M1(Course A) 18 Tue M1(Course B) M4 M1(Course B) 19 Wed M1(Course C) M4 M1(Course C) 20 Thu M2(Course A) M4 M2(Course A) 21 Fri M5(Special Lecture 1) 22 Sat Off 23 Sun Off 24 Mon M1(Course A) M4 M1(Course A/Exam) 25 Tue M1(Course B) M4 M1(Course B/Exam) 26 Wed M1(Course C) M4 M1(Course C/Exam) 27 Thu 28 Fri 29 Sat Orientation, Registration, Health checkup Immigration Bank Account Welcoming ceremony, Campus Tour M5(Industrial Site Visit 1) 1st class: 09:00~10:15(75min), 2nd class: 10:30~11:45(75min), 3rd class: 13:30~14:20(50min), 4th class: 14:30~15:20(50min), 5th class: 15:30~16:20(50min) Remark - September 2015 (BT/ET) Day 1st class 2nd class 3rd class 4th class 5th class 30 Sun Off 31.Aug Mon M2(Course B) M4 M2(Course B) 1.Sep Tue M2(Course C) M4 M2(Course C) 2 Wed 3 Thu M2(Course A) M4 M2(Course A) 4 Fri M2(Course C) M4 M2(Course C) 5 Sat Off 6 Sun Off 7 Mon M2(Course B) M4 M2(Course B) 8 Tue M2(Course C) M4 M2(Course C) 9 Wed M2(Course B) M4 M2(Course B) 10 Thu 11 Fri 12 Sat Off 13 Sun Off 14 Mon M3(Course A) M4 M3(Course A) 15 Tue M3(Course B) M4 M3(Course B) 16 Wed M2(Course B) M4 M2(Course B) 17 Thu 18 Fri 19 Sat 20 Sun 21 Mon M3(Course A) M4 M3(Course A) 22 Tue M3(Course B) M4 M3(Course B) 23 Wed M3(Course A) M4 M3(Course A) 24 Thu M3(Course B) M4 M3(Course B) 25 Fri 26 Sat 27 Sun 28 Mon Self-Research M5(Field Trip 2) M2(Course C) M4 M2(Course C) M5(Industrial Site Visit 1) Off M5(Special Lecture 2) Thanksgiving Holiday 1st class: 09:00~10:15(75min), 2nd class: 10:30~11:45(75min), 3rd class: 13:30~14:20(50min), 4th class: 14:30~15:20(50min), 5th class: 15:30~16:20(50min) Remark - October 2015 (BT/ET) Day 1st class 2nd class 3rd class 4th class 5th class 29 Tue Thanksgiving Holiday 30.Sep Wed M3(Course A) M4 M3(Course A) 1.Oct Thu M3(Course B) M4 M3(Course B) 2 Fri M5(Special Lecture 3) 3 Sat Off 4 Sun Off 5 Mon M3(Course C) M4 M3(Course C) 6 Tue M3(Course D) M4 M3(Course D) 7 Wed M3(Course E) M4 M3(Course E) M3(Course F) M4 M3(Course F) 8 Thu 9 Fri Self-Research 10 Sat Off 11 Sun Off 12 Mon M3(Course C) M4 M3(Course C) 13 Thu M3(Course D) M4 M3(Course D) 14 Wed M3(Course E) M4 M3(Course E) 15 Thu M3(Course F) M4 M3(Course F) 16 Fri M5(Field Trip 3) 17 Sat Off 18 Sun Off 19 Mon M3(Course C) M4 M3(Course C) 20 Tue M3(Course D) M4 M3(Course D) 21 Wed M3(Course E) M4 M3(Course E) 22 Thu M3(Course F) M4 M3(Course F) 23 Fri 24 Sat 25 Sun 26 Mon M3(Course C) M4 M3(Course C) 27 Tue M3(Course D) M4 M3(Course D) 28 Wed M3(Course E) M4 M3(Course E) M3(Course F) M4 M3(Course F) M5(Industrial Site Visit 3) 29 Thu 30 Fri Commencement, Farewell Party 31.Oct Sat Preparing to Leave , Departure 1st class: 09:00~10:15(75min), 2nd class: 10:30~11:45(75min), 3rd class: 13:30~14:20(50min), 4th class: 14:30~15:20(50min), 5th class: 15:30~16:20(50min) Remark Ĵ Program Management G Educational Institution(Graduate School of International Studies) The Graduate School of International Studies at Ajou University was established in 1996 as a pioneer of professional studies programs in Korea. The founding motivation of Ajou GSIS was to meet the growing global demand for international academic institute. At present, the Ajou GSIS has over 400 alumnus in more than 55 countries worldwide, who are working at government agencies and global enterprises and playing an important roles in their respective positions. Ajou GSIS encourages you to explore the very best out of your time and talents as the very potential leader of the coming world. Educating the future leaders for an increasingly complex global society in both a professional and academic institution? to promote mutual understanding, peace, and prosperity, both regionally and globally. You will join diverse student community from different parts of Korea as well as from more than 30 different countries. You will have an interdisciplinary focus that will help you develop your communication, technology, decision making, and teamwork skills as you prepare for a career in international fields. ٢ Departments International Business International Trade International Development and Cooperation NGO Studies ٢Nationality of Current students Ghana, Guatemala,Nigeria, Nepal, German, East-Timor, Liberia, Mongol, Bangladesh, Vietnam, Solomon Island, Azerbaijan, Afghanistan, Ethiopia, Uganda, Uzbekistan, Ukraine, Indonesia, China, Cameroon, Kazakhstan, Cambodia, Columbia, Kirgizstan, Tanzania, Pakistan, France, Finland Administration Officer Dept. GSIS OIA Name position Job Description Tel E-Mail Jay Ick Lim Dean General Manager +82312192722 limjay@ajou.ac.kr Hyukpyo Kwon Director Management, Directing +82312191551 kwon104@ajou.ac.kr Dong-Hyun Noh Assi. Dir. +82312193613 gsis@ajou.ac.kr Jeong-Yeong Choi Assi. Dir. +82312191552 gsis@ajou.ac.kr Hee Jung Lim Coordinator +82312191553 gsis@ajou.ac.kr Kyungrim Kim Coordinator +82312193597 gsis@ajou.ac.kr Sumin Kim Coordinator +82322191555 gsis@ajou.ac.kr Hayoung Park Coordinator +82322193615 gsis@ajou.ac.kr Intern 1 Intern Admission Data-base +82312193596 gsis@ajou.ac.kr Intern 2 Intern Alumni Data-base +82312193596 gsis@ajou.ac.kr Intern 3 Intern Student Activities +82312193596 gsis@ajou.ac.kr Jae-Eun Kim Associate Director Immigration +82312192925 admission@ajou.ac.kr Management of Special Programs Admission, Graduation, Academic rules, Statistic Class, Activities Specialist for Argentine Program Short KOICA program, Accounting Accounting, Nubi, Pre-GSIS G Campus Facilities 1) Ajou University Central Library Ajou University Central Library was founded on Mar. 15th 1973 to fulfill our education objectives clearly stated in our school regulations. Our goal is to contribute to the students and faculty's studies and research by collecting, arranging and providing academic information. At the beginning the total floor space of the library was only 876 G and there was a total of 120 seats in the reading room. We initiated our service on Apr. 2nd 1973 with 1272 books and 1 librarian. Ajou University Central Library was reformed as the school grew to university status. With the donation of 5 billion won from Kim Woo Joong, the ex-president of Daewoo group. It has Lending and Reading Room, Newly-Published Material Room, Reference Room, Reserve Book Room, Digital Library Develop Room, Multimedia Information Room and Information Support Room on the 1st floor, Periodicals Room on the 2nd floor, Liberal Arts/Social Science Room and Linguistics/Natural Science Room on the 3rd floor, and National Tests Information Room on the 4th floor with a floor space of 13,310 . There are 5 General Reading Rooms on each floor. Now we have approximately 880,000 books and 2,000 seats in the reading rooms. 2) Ajou Service Center Ajou Service Center is located on the first floor of the New Student Union Building and serves the university’s students, staff and faculty members in various ways. 3) Ajou University Dormitory Ajou University offers various type of accommodations for providing comfort and modern technology to residents. Ajou University Dormitory "Woncheon Dormitory Complex" houses over 2,300 domestic and international residents consisting of 4 buildings. At Hwa-hong Hall, over 300 international students can accommodate either in two-people-shared room or in four-people-shared room. We hope native Korean students and international students alike will be able to learn about each other’s' cultures and broaden their sense of international perspective. 4) Cafeterias on Campus There are many places to eat on campus. Besides the dormitory cafeteria, there’s several eating places on the campus. Also there are small snack areas on the first floor of Dasan Hall and Sungho Hall, and at the basement of Yulkok Hall. Cafeteria Location Hours Food Served Dormitory Dining Hall Dorm. Dining Hall 8AM~7PM Korean/Western meal Sun In Jae Basement, Songjae Hall 9AM~8PM Korean home meal, bakery Ahyang Cafeteria Behind Wonchun Hall 9AM~6:30PM Korean/Western meal Sinsegye 1st Floor, Student Union BL 9AM~6:30PM Korean/Western meal Sungho Hall 1 Floor,SunghoHall st 9AM~7PM Snakcs, Beverages Dasan Hall 1 Floor,DasanHall st 9AM~8PM Snacks, Beverages Yulkok Hall Basement, Yulkok Hall 9AM~6PM Snacks, Beverages Paldal Hall 1stFloor,Paldal Hall 9AM~6PM Snacks, Beverages 5) Health Care ٢Infirmary For any minor health problems such as cold or digestion, you can visit the infirmary. ّLocation : Rm 227 new student union building ّ Tel: 031-219-1597 ّ Office Hours : AM 9:00 – PM 6:00 ٢Ajou University Hospital International Health Care Center Ajou International Health Care Center(IHCC) provide total care of medical and communication service with multi languages including English. ّLocation : First floor Well-Being Health Center ّ Tel: 031-219-4312 ّ Office Hours : AM 9:00 – PM 6:00 Available Services Appointment 1:1 Care for outpatients Private Insurance Consultation English Bill & Certificate Issue Service Multi languages including English Inpatient & ER patient coordinators Procedure Registration Evaluation Payment Treatment & Tests Prescription 6) Lounge and Fitness Facility Location Service Global Lounge 1st Floor of Yulgok Hall Use of computer/Lounge Ajou Student Service Center 1st Floor of New Student Union Building Certificate Issuance Service On-Campus Gymnasium 1st Floor of Gymnasium Sports Facilities 7) Others ٢Standard Chartered Bank, Korea Open a bank account Deposit and withdraw money etc. ّLocation : The first floor of student union building 1 ّ Tel : 031-219-2291 ّ Office Hours : AM 9:30 – PM 5:00 ٢Post Office Domestic & Int'l mail / parcels ّ Location : The first floor of student union building 1 ّ Tel : 031-219-2275 ّ Office Hours : AM 9:00 – PM 6:00 ٢Photo Studio Take a picture ّ Location : Basement of Yulgok Hall ّ Tel : 031-219-2286 ّ Office Hours : AM 9:00 – PM 6:00 ٢Photocopy Room Make a copy of any paper Material ّ Location : Basement of Yulgok Hall ّ Tel : 031-219-2276 ّ Office Hours : AM 9:00 – PM 6:00 ٢ATM Withdraw money etc. 8) Accommodation Bec.ar Program Participants Off-Campus Residence: 2 people shared room Value Hotel World Wide High End Address: Hyowon-ro 299, Paldal-Gu Suwon, Gyeonggi Province Distance: Value Hotel World Wide High Endis located10 minutes away from the university by bus. Equipment Equipment Room Bed, Table, Closet, Refrigerator, Telephone, Sofa, LCD TV, Hair Dryer Bathroom Bidet, Mini-bar, Complimentary Water, Coffee Machine Laundry Coin Laundry Machine Gymnasium th Business Center 7 floor English, Korean, Chinese, Japanese available on PC and printer Terrace 9 th floor Pictures in Value Hotel World Wide High End <Room> <Bathroom> <Restaurant> <Restaurant> <Front View of Building> <Gymnasium> G G G G G G G G G Ajou IT, BT, NT, ET G G G G G G G G G G G G G G G G G G G G G G G G G G Contents 1. IT(Information Technology) G G G G 2. BT(Bio-Medicine, Bio-Pharmacy) 3. NT(Nanotechnology) 4. ET(Energy Technology) G G G G G G G G Information Technology IT IT(Information Technology) Graduate Programs in the College of Information Technology of Ajou University Department of Electrical and Computer Engineering Introduction The Department Electrical and Computer Engineering at Ajou University aims to cultivate competent engineers equipped with professional knowledge and leadership so that they can contribute to the welfare of the modern society. Toward this goal, the department offers students unique opportunities to study and carry out research in areas including electronic devices and materials, multimedia network and communications, microwave radio communications, computers, and automatic control systems. The department has post-bachelor programs leading to a master degree and a doctoral degree. Another program, called the integrated degree program, is also offered for those who have a bachelor degree and wish to obtain a doctoral degree. The department has various laboratories for specific areas of study and research, to which students will be assigned and work under the supervision of faculty upon admission to a program. Ajou University College of Information Technology Brochure Degrees Doctoral Program Degree requirements · Master Degree · A minimum of 4 semesters · Doctoral Degree · A minimum of 69 credits, 60 of which must · Integrated Master and Doctoral Degree be lecture credits · A minimum GPA of 3.0 out of 4.5 Master Program · Passing the English examination or equivalent qualification Degree requirements · A minimum of 4 semesters · A minimum of 30 credits, 24 of which must be lecture credits · A minimum GPA of 3.0 out of 4.5 · Passing the English examination or · Passing the qualifying examination · Publication or acceptance of at least two first-authored papers in Korean journals or one first-authored paper in an SCI journal · Thesis equivalent qualification · Passing the qualifying examination · Publication of at least one paper in conference proceedings Coursework • 60 credits of major courses · 6 credits of required courses and 54 · Publication or submission of at least one credits of elective courses. (Up to 24 first-authored paper to a journal, or at credits can be waived if acquired in a least one patent application · Thesis master program) • 9 credits of research Coursework · 24 credits of major courses : 6 credits of required courses and 18 credits of elective courses · 6 credits of research Empowering the Future of the World IT(Information Technology) IT(Information Technology) Degree Programs Integrated Master and Doctoral Program Degree requirements · A minimum of 8 semesters · A minimum of 63 credits, 60 of which must Curriculum Courses Course Titles Required Advanced Physical Electronics / Advanced Electromagnetic Field Theory / Signals and Systems Theory / Digital System Design / Control Systems Theory Electives Advanced Optoelectronics / Advanced Physical Electronics / be lecture credits Compound Semiconductor Devices / High Frequency Integrated Circuit Design / Nano-Micro Device Fabrication / Nano-Micro System Design / Optical Communication System / Power Semiconductor Devices / · A minimum GPA of 3.0 out of 4.5 · Passing the English examination or Solid-State Lighting / Advanced Topics in Semiconductor / Advanced Electromagnetic Field Theory / equivalent qualification · Passing the qualifying examination Advanced Topics in Microwave Engineering / Antenna Theory and Design / Electromagnetic Interference and Compatibility / Electromagnetic Scattering / Electromagnetic Wave Propagation / Guided-wave Theory & Analysis / · Publication or acceptance of at least one first-authored paper in an SCI journal · Thesis Microwave Devices and Circuits / Microwave Structure Analysis / Advanced computer Networks / Advanced Digital Communications / Advanced Wireless Communication Systems / Advanced Wireless Networks / Error Control and Coding Theory / Performance Analysis of Communication Networks / Coursework • 54 credits of major courses · 6 credits of required courses and 48 Probability and Stochastic Process / Queuing Systems / Special Topics in Communication Systems / Computer Visio / Cryptography / credits of elective courses. • 9 credits of research Digital Image Coding / Advanced Digital Image Processing / Information Theory / Pattern Recognition Theory / Advanced Signals and Systems Theory / Special Topics in Signal Processing / Advanced Computer Architecture / Advanced Software Design / Special Topics in Computer / Data Structure and Computer Algorithms / Discrete Event Systems / Embedded System / Parallel and distributed Systems / Real-Time Operating Systems / SOC Design / Embedded System Testing / Advanced Topics in Control Engineering / Digital Control / Energy Conversion System / Estimation Theory / Intelligent Control System / Linear System / Optimization Theory / Robot Control Theory / Servo System Ajou University College of Information Technology Brochure Name Major Ph.D from Email @ajou.ac.kr Cho, We-Duke Communication System KAIST* chowd Choi, Tae-Young Image Signal Processing University of d'Aix-Marseille III taeyoung Choi, Yearn-Ik Power Semiconductor Devices KAIST* yearnik Chung, Ki-Hyun Computer Architecture Purdue University khchung Chwa, Dong-Kyoung Control Systems Seoul National University dkchwa Hong, Suk-Kyo Control Systems Seoul National University skhong Jo, Jung-Yol Semiconductors and Materials Princeton University jungyol Kam, Dong-Gun Signal Integrity, EMI/EMC KAIST* kam Kim, Jae-Hyun Wireless Network Hanyang University jkim Kim, Sang-Bae Optoelectronics KAIST* sbkim Kim, San-Gin Photonic Devices University of Minnesota sangin Kim, Yong-Deak Computer Systems Yonsei University yongdkim Kim, Young-Kil Bioelectronics ENST ykkim Kim, Young-Jin Embedded Software Seoul National University youngkim Koo, Hyung-Il Computer Vision Seoul National University hikoo Kwak, No-Jun Pattern Recognition Seoul National University nojunk Kwon, Ick-Jin RF/Analog IC KAIST* ijkwon Lee, Chae-Woo Network University of Iowa cwlee Lee, Hai-Young Microwave Engineering University of Texas, Austin hylee Lee, Jae-Jin Nano Materials and Devices Northwestern University jaejin Lee, Ja-Sung Control Systems University of S. California jsung Lee, Jung-Won Embedded & Software Engineering Ewha Womans University jungwony Lee, Kee-Keun Solid-State Electronics Arizona State University keekeun Lee, Kyo-Bum Power Electronics Korea University kyl Lim, Han-Jo Semiconductor Physics University of de Montpellier 2 hanjolim Na, Sang-Sin Communication University of Michigan sangna Oh, Seong-Keun Communication Systems KAIST* oskn Park, Ik-Mo Microwave, Teraherz University of Illinois ipark yong Photonics Park, Yong-Bae EM Field Analysis KAIST* Park, Seong-Jin Hybrid Systems Theory KAIST* parksjin Sunwoo, Myung-Hoon VLSI/SoC Design University of Texas, Austin sunwoo Yang, Sang-Sik MEMS, Automatic control U.C., Berkeley ssyang Yoon, Won-Sik Wireless Communication and Network KAIST* wsyoon ※KAIST : Korea Advanced Institute of Science and Technology Empowering the Future of the World IT(Information Technology) IT(Information Technology) Faculty Member Department of Computer Engineering Introduction Department of Computer Engineering of Ajou University produces excellent professional engineers who lead the information, communication, computer science and engineering fields in the coming years. The department offers the professional masters and doctoral degrees and requires students to get through more practical and specialized coursework. It also keeps close relationships with its industrial partners, which are involved in curricular activities and research collaboration. Ajou University College of Information Technology Brochure Degrees Doctoral Program Degree requirements · Master Degree · A minimum of four semesters · Doctoral Degree · A minimum of 69 credits and 60 of them · Integrated Master and Doctoral Degree should be taken from the course work · A minimum GPA of 3.0/4.5 Master Program · Pass the English test or submit the equivalent qualification Degree requirements · A minimum of four semesters · A minimum of 30 credits and 24 of them should be taken from the course work · Pass the qualifying examinations · Fulfill the publication requirement - Accepted at least one research paper at a SCI or SCIE-listed journal. The student · A minimum GPA of 3.0/4.5 should be the first author of the paper. · Pass the English test or submit the (a student in the integrated master and equivalent qualification · Pass the qualifying examinations · Fulfill the publication requirement - Accepted and present at least one doctoral degree program can fulfill this requirement only) - Accepted at least three research paper to a KRF (Korea Research Foundation : 한국 research paper at a domestic or an 학술진흥재단) listed journal and accepted international conference before the final and present at least one research paper dissertation defense. The student should at an international conference (which be the first author of the paper. is IEEE or ACM sponsored or Lecture - Submit at least one research paper to Note Series) before the final dissertation either a SCIE-listed or a KRF (Korea Research Foundation : 한국학술진흥재 defense. The student should be the first 단) listed journal. The student should author of the paper for both cases. · A doctoral thesis be the first author of the paper. If your submitted paper is accepted and Coursework published before the final dissertation • 60 credits of major courses defense, your conference requirement · 9 credits of core courses and 51 credits of will be waived. elective courses. (Up to 24 credits can be · A master thesis waived if acquired in master program) • 9 credits of research Coursework · 24 credits of major courses : 9 credits of core courses and 15 credits of elective courses · 6 credits of research Empowering the Future of the World IT(Information Technology) IT(Information Technology) Degree Programs Integrated MS and Doctoral Program Degree requirement Curriculum Courses Group* Course Titles Required** Theory Advanced Algorithms / Advanced Stochastic Processes / Advanced Theory of Computation System Advanced Computer Architecture / Advanced Operating Systems / System Performance Evaluation · Pass the qualifying examinations Communications Computer Networks / Computer Communication Performance Analysis · Fulfill the publication requirement S/W Application Advanced Database / Advanced Information Security · A minimum of eight semesters · A minimum of 63 credits and 54 of them should be taken from the course work · A minimum GPA of 3.0/4.5 · Pass the English test or submit the equivalent qualification - Accepted at least one research paper at Electives Advanced Computer Vision / Web Security / Information Retrieval / Computational Biology / a SCI or SCIE-listed journal. The student Advanced Artificial Intelligence / Distributed Algorithms / Topics in Programming Languages / Object Oriented Methods / should be the first author of the paper. (a student in the integrated master and Advanced Computer Graphics / Computer System Security / Advanced Software Engineering / Service Oriented Computing / Distributed Component Systems / doctoral degree program can fulfill this requirement only) · A Integrated MS and Doctoral thesis Ubiquitous Security and Privacy / Special Topics in Information Security Applications / Topics in Database / Mobile Computing Systems / Mobile Embedded Networks / Real-Time Systems / Advanced Topics in Systems and Applications / Distributed System Design / Broadband Information Networks / Advanced Multimedia Communications / Mobile Communications and Networks / Wireless Communications / Special Topics I in Computer Communications / Special Topics II in Computer Communications / Computer Network Security / Ubiquitous Sensor Networks / Theory of Industrial Security / IT Security Evaluation Theory / Cloud Computing / Radio Resource Management / Security Wireless Communication Coursework • 54 credits of major courses · 9 credits of core courses and 45 credits of elective courses. • 9 credits of research ※ The department divides courses into theory and 3 other groups according to faculty members' major research interests ※ 3courses are required, each one from 3 different groups Ajou University College of Information Technology Brochure Email @ajou.ac.kr Name Major Ph.D from Byeon, Kwang-June DBMS University of Southern California byeon Cho, Young-Jong Computer Network KAIST* yjcho Choi, Young-June Wireless Communications Seoul National University choiyj Choi, Kyung-Hee OS, Real time System University of Paul Sabatier khchoi Chung, In-Ha Decision Theory Michigan State University ihjung Chung, Tae-Sun Database Seoul National University tschung Hong, Man-Pyo Computer Architecture Seoul National University mphong Kang, Kyung-Ran Computer Network KAIST* korykang Kim, Dong-Yoon Computer Vision MIT dykim Kim, Jai-Hoon Distributed Systems Texas A&M University jaikim Kim, Ki-Hyung Embedded System KAIST* kkim86 Kim, Min-Koo Artificial Intelligence Pennstate University minkoo Kim, Sung-Soo Computer System Texas A&M University sskim Ko, Young-Bae Wireless&Mobile Computing Texas A&M University youngko Lee, Jung-Tae Programming Languages Seoul National University jungtae Lee, Seok-Won Software Engineering George Mason University leesw Lim, Jae-Sung Mobile Computing KAIST* jaslim Oh, Sang-Yoon Software & Web System Indiana University syoh Park, Seung-Kyu Computer Architecture L'institute National Polytechnique de Grenoble sparky Roh, Byeong-Hee Computer Communication KAIST* bhroh Ryu, Ki-Yeol Programming Languages KAIST* kryu Shon, Tae-Shik Information Security Korea University tsshon Wee, Kyu-Bum Algorithms Indiana University kbwee Wee, Young-Chul Computer Vision State University of New York ycwee Yeh, Hong-Jin Computer Arithmetic University Claude Bernard- hjyeh Lyon 1 Yoo, Seung-Wha Computer Systems University of Kansas ※KAIST : Korea Advanced Institute of Science and Technolo Empowering the Future of the World swyoo IT(Information Technology) IT(Information Technology) Faculty Member Department of Digital Media Introduction Media is a field to study theories and technologies to create and maintain a variety of digital contents, including web, computer games, computer animation, digital films and digital broadcasting. The Department of Digital Media is aiming to cultivate qualified engineers and technical artists to create digital contents so that they could play a pivotal role in today’s information society. Digital content creation requires broad and in-depth knowledge of planning, software engineering, and digital design. Thus, the department provides the graduate curriculum covering all these areas with equal importance, emphasizing on computer games, 3D computer graphics theories, and digital design. Ajou University College of Information Technology Brochure Degrees Doctoral Program Degree requirements · Master Degree · A minimum of 4 semesters · Doctoral Degree · A minimum of 69 credits, 60 of which must · Integrated Master and Doctoral Degree be lecture credits · A minimum GPA of 3.0 out of 4.5 Master Program · Passing the English examination or equivalent qualification Degree requirements • Completion of Master program requires · Passing the qualifying examination · Publication or acceptance of at least two · A minimum of 4 semesters first-authored papers in Korean journals · A minimum of 30 credits, 24 of which must or one first-authored paper in an SCI be lecture credits · A minimum GPA of 3.0 out of 4.5 journal · Thesis · Passing the English examination or equivalent qualification Coursework · Passing the qualifying examination • 60 credits of major courses · Publication or submission of at least one · 6 credits of required courses and 54 first-authored paper to a journal. · Thesis credits of elective courses. (Up to 24 credits can be waived if acquired in a master program) Coursework • 9 credits of research • 24 credits of major courses · 6 credits of required courses and 18 credits of elective courses. • 6 credits of research Empowering the Future of the World IT(Information Technology) IT(Information Technology) Degree Programs Integrated Master and Doctoral Program Degree requirements · A minimum of 8 semesters · A minimum of 63 credits, 60 of which must Curriculum Courses Course Titles Required Digital Media Seminar I, II Electives Game Producer / Advanced Game Design / Analysis of Virtual World / Topics in Game Production / Serious Game I / Serious Game II / be lecture credits Serious Game Design I / Serious Game Design II / Serious Game Project I / Serious Game Project II / Edutainment I / Edutainment II / Game Therapy I / Game Therapy II / Digital Design Theories / · A minimum GPA of 3.0 out of 4.5 · Passing the English examination or Design Research / Color Theories / Interface Design / Information Visualzation Studio / Media Design Studio / equivalent qualification · Passing the qualifying examination Interactive Media Design / User Experience Design Methodology / Designing User Experience for New Media / Advanced Motion Graphics / Advanced Web Design / Code for Digital Media / Physical interface Design / · Publication or acceptance of at least two first-authored papers in Korean journals or one first-authored paper in an SCI Film Theory / Scenario Seminar / Advanced Film Production / Production Design / Digital Visual Effect / 3D Animation Workshop / journal Digital Images Analysis / Media Industry-Educational Project / Digital Creature Design / Advanced Sound Theory / Advanced Sound Analysis / Advanced Sound Production / · Thesis Coursework Theories in New Media / Research Methods / Digital Broadcasting / New Media Research I / New Media Research II / Media Staticstics I / • 54 credits of major courses · 6 credits of required courses and 48 Media Staticstics II / Advanced Media & Human 1 / Advanced Media & Human 2 / Media Prosumer I / Media Prosumer II / Media Therapy I / Media Therapy II / Advanced Computer Graphics / credits of elective courses. • 9 credits of research Methods for Problem Solving / Advanced Animation Theories / Topics in Advanced Animation I / Topics in Advanced Animation II / Geometric and Solid Modeling / Advanced Rendering Theories / Topics in Advanced RenderingI / Topics in Advanced Rendering II / Advanced Modeling Theories / Topics in Advanced Modeling I / Topics in Advanced Modeling II / Industry-Educational Project I / Industry-Educational Project II / Industry-Educational Project III Ajou University College of Information Technology Brochure Name Major Ph.D from Email @ajou.ac.kr Chang, Woo-Jin Film Theory and Criticism Hanyang University (MS) woojin71 Choi, Jung-Ju Computer Graphics Pohang University of Science and Tech.(PhD) jungju Kim, Ji-Eun Computer sound La Schola Cantorum(MS) jieunkim Kim, Hyo-Dong Communication Rutger University(PhD) hkimscil Kim, Hyun-Hee Design New York University Tisch School of Arts (MS) huni wkoh Koh, Wook Computer Animation & Game U.C., Berkeley(PhD) Kyung, Min-Ho Computer Aided Design Purdue University(PhD) kyung Lee, Ju-Yeop Graphics Design Pratt Institute (MS) maldes Lee, Kyung-Won Digital Media Pratt Institute (MS) kwlee Lee. Yun-Jin Computer Graphics Pohang University of Science yunjin and Tech.(PhD) Lim, You-Sang Computer Animation Hongik University (MS) ysang Oh, Gyu-Hwan Computer Graphics KAIST*(PhD) drghoh Shin, Hyun-Joon Computer Graphics KAIST*(PhD) joony Suk, Hae-Jung Animation Hongik University(MS) dbdip ※KAIST : Korea Advanced Institute of Science and Technolo Empowering the Future of the World IT(Information Technology) IT(Information Technology) aculty Member Bio-Medicine, Bio-Phamacy BT So Many Question Marks in My Head When told not to go, I want to go even more. When told not to do something, I will do my utmost to do it. I can stand embarrassment but not curiosity. Why? My head is full of question marks. When it feels like exploding, I take them out carefully and throw them to the sky. Doctors are all over TV, in soap operas, in documentaries. Nothing else grabs my attention like the doctors on TV. In The Big White Tower, a Korean drama, a team of doctors in white coats walks down a hallway conducting morning rounds. That is so cool. I can feel the sanctity of a profession that saves lives wearing the white coat. When I watch the American program Grey’s Anatomy, I see that doctors are also human beings who make mistakes and get excited at times. 1 BT(Bio-Medicine, Bio-Phamacy) BT(Bio-Medicine, Bio-Pharmacy) why ? How do doctors bear such a tough life? What kind of people are they? What are their dreams? Why is Ajou University School of Medicine (AUSOM) so special among other medical schools? The doctor. The path of the doctor. AUSOM. My curiosity will not be satisfied just by quickly googling these words online. I am resolved to answering these questions one by one. AUSOM, a place where your question marks turn into exclamation points. Cultivating Global Leaders in Medicine Comprising Small Groups but Offering Diverse Opportunities Representing Youth and Dynamism The Symbol of AUSOM ‘A Traverse Table’ This bronze plate, which has graced the lobby of the medical school building since the school’s founding, serves as a guidepost for those embarking on the path towards becoming a doctor. Cultivating Global Leaders in Medicine BT(Bio-Medicine, Bio-Phamacy) BT(Bio-Medicine, Bio-Pharmacy) Learn at AUSOM and Branch Out into the World There is no need to try to answer the question, “Why Ajou University School of Medicine?” All one needs is a heart full of passion. AUSOM is like a beating heart. As the heart pumps blood to the body, students at AUSOM learn from this core institution in the center of Asia and branch out into the world to show their passion. Their bold footsteps cannot be impeded. Cultivating Global Leaders in Medicine Every summer, 12 graduating students are selected for overseas training in the United States. These students, with full financial support from AUSOM, Overseas Training Program are given a chance to experience the reality of foreign medical training for 6 weeks during their summer vacation. At present, AUSOM has exchange programs with the medical schools of the State University of New York (SUNY) at Stony Brook and the University of Florida (UF). We are also promoting exchange programs with other universities in Europe. Ja Young Jeon (Entry Class of 2002) “Now, I can do anything anywhere in the world.” SUNY is located near the beach, and the surrounding scenery was great. At first, I was a little worried about staying alone in an unfamiliar place but after the 6-week experience I achieved confidence. I was able to attend lectures and hospital trainings with many foreign students in SUNY. Now, I can do anything anywhere in the world. Seo, Seung Jo (Entry Class of 2000) >> Cultivating Global Leaders in Medicine In addition to providing volunteer services throughout Korea, AUSOM sends medical teams for international social services every year as part of International Volunteerism the Overseas Student Volunteer Services promoted by the Korean University Council for Social Service. As such, our students develop into global doctors with tolerance. BT(Bio-Medicine, Bio-Pharmacy) “Having a love for humanity is the most essential quality to being a doctor.” To provide social services, I have been to Uganda, East Timor, India, and more. I have learned unforgettable lessons while witnessing gruesome scenes of continuing starvation. I have met those who continue to have hope under the harsh conditions of domestic warfare. Having a love for humanity, all humanity is the most essential quality to being a doctor. Kim, Dong Hoon (Entry Class of 1999) >> Cultivating Global Leaders in Medicine Every year, numerous international academic symposia are held at AUSOM . We invite renowned scholars from in and out of Korea to exchange and dis- International Academic Symposia cuss the most current medical knowledge. We also hold annual seminars for medical education and curriculum development workshops by inviting professors from the Johns Hopkins University School of Medicine. International Symposium on Stem Cell Therapy and Genomic Research (Ajou University Hospital Auditorium) Stephen T. Holgate, M.D. “I dream of becoming a global doctor by exchanging high-tech medical knowledge with world figures.” In addition to studying the subjects on the school curriculum, attending international symposia and seminars was also useful for learning medicine. Listening to research presentations of world famous scholars makes my heart beat a bit quicker because I can feel their passion for the development of medicine and medical practice. I am studying English very hard so that I can participate in these events more actively. Kang, Eun Jung (Entry Class of 2002) >> Ajou University School of Medicine is recognized nationally and interna- Cultivating Global Leaders in Medicine tionally for the research results achieved through our state-of-the-art lab- Research Centers oratories and research centers. AUSOM has esteemed professors who strive for perfection. Institute for Medical Sciences (Yup Kang, Ph.D.) Center for Injury Prevention & Community Safety Regional Clinical Trial Center (RCTC) (Hae Sim Brain Disease Research Center (SRC) Promotion (Joon Pil Cho, M.D., Ph.D.) Park, M.D., Ph.D.) Center for Cell Death Regulating Biodrug (Young Center for Clinical Epidemiology (Nam Han Cho, Cell Therapy Center (Byoung-Hyun Min, M.D., Don Lee, Ph.D.) M.D., Ph.D., C.C.D.) Ph.D.) Genomic Research Center for Gastroenterology Chronic Inflammatory Disease Research Center Research Institute for Neural Science & (Sung Won Cho, M.D., Ph.D.) (Ilo Jou, M.D., Ph.D.) Technology (Jai Sung Noh, M.D.) Institute for Neurodegeneration & Stem Cell “Extending the fame of AUSOM with world class medical research” Cell Therapy Center leading developments in biotechnology Professor Byoung-Hyun Min, M.D., Ph.D. It is essential that a medical scientist participate in biotechnologyassociated research. Medical doctors recognize that the results of biotechnology research are useful to people. In that perspective, the contributions that AUSOM’s [Cell Therapy Center] make to the advancement of biotechnology in Korea is noteworthy. Professor Min, the Center’s director, was the first orthopedic surgeon in Korea to succeed in the transplantation surgery of the cartilage cell in 1996. He says, “For a doctor to implement in research the medical demands of today, it is cardinal that doctors participate in national research.” The Center focuses on finding ways to manufacture cells, tissues and organs needed by patients. Making cells that do the terminal works in the body is the primary subject of research at this center. This is a subject so important that is included in big national research subjects. The Center is proud of its aseptic room where researchers can produce the cell cures that can function in various parts of our bodies. BT(Bio-Medicine, Bio-Pharmacy) Research (Young Hwan Ahn, M.D., Ph.D.) Research Institute for Neural Science & Technology developing historical cures for brain disease Professor and thus the world nowadays calls the condition Alzheimer’s disease. Medicine is a profession that mostly needs self-development and selfstudy. Every doctor’s creative thinking is indeed the main driving force for Byoung Joo Gwag, Ph.D. the development of medicine. Neurology is definitely one of the priority research areas at Ajou University School of Medicine. Since AUSOM took its leadership role in this field in 1995, many researchers are doing their best in brain disease research, such as cerebral apoplexy and dementia. How brain diseases Regional Clinical Trial Center (RCTC) holding patient needs first Professor Hae Sim Park, M.D., Ph.D. occur and how we can cure them are the focus of our research. AUSOM garnered fame throughout the world by developing a new drug As Ajou University Hospital is the only tertiary medical facility in called AAD-2004 for brain disease dementia treatment, which is now Gyeonggi-Do, many patients with various diseases come from not only being tested in the U.S. and Europe. If this new drug is certified for safe- the metropolitan area but also the whole country. This is how AUSOM ty, a cure for dementia may be possible within 5-6 years. At the center of is able to conduct the variety and extent of our clinical research, empha- this epochal new treatment is Professor [Byoung Joo Gwag] of the sizing early diagnosis and new treatment for all sorts of diseases. Department of Pharmacology, who has a very important role and heavy Professor Park, the chief of the Center, has contributed greatly to garner- responsibility in [Research Institute for Neural Science & Technology]. His ing recognition for the research facility inside and outside of the country. 10-year journey to find a new treatment for dementia culminated in SCI (Science Citation Index) is regarded as a measure for research capa- developing the fundamental techniques for the new drug. He emphasizes bility in the fields of science and technology. Professor Park, who the importance of creative thinking. authored 26 SCI articles in 2006 alone, is well known as a highly capa- A doctor named Alzheimer in Germany started to wonder about a patient ble professor. She is also an expert in allergy and works as a deputy edi- who had unique symptoms of losing memories and making new memo- tor for the journal [Allergy], a publication of the European Academy of ries. He researched these symptoms, which he might just have ignored, Allergology and Clinical Immunology. The Center is concerned with the effects of rapid industrialization, drugrelated allergies, asthma, nasal catarrh, and hives, among others. In particular, research on allergies related to drugs has global implications, and thus we are progressing collaborated research with other facilities within the country, US and Europe. Comprising Small Groups but Offering Diverse Opportunities BT(Bio-Medicine, Bio-Pharmacy) A New Medical Paradigm Through Elite Education With just 40 students per year and 321 professors on the faculty, the small student to professor ratio is a key to AUSOM’s success. The education and clinical training at Ajou University Hospital combined with the professors’ concern promote outstanding doctors. Comprising Small Groups but Offering Diverse Opportunities Interview with the Dean “Ajou University School of Medicine is a laboratory for self development.” The 21st century is an era of change and diversity. AUSOM can quickly and actively adapt to the rapid changes of the world. AUSOM is much more than a training school for future doctors. This place is a lab to test students and stretch their talents. Students at AUSOM have no fear in expressing themselves. Dean In Kyoung Lim says that she wishes for students to stretch their talents and become respected doctors rather than mediocre doctors. Nowadays, she is increasing academic exchanges with universities from abroad, as well as extending research abilities now that we have been selected as the BK21 Research Program. Medicine in the 21st century is prediction medicine, which predicts the patient’s medical examination and treatment and its results. Thus, collaborated research among the industries, academic fields, and research centers is of prime concern. AUSOM has reached its current state in just a short period thanks to the continuous investments and the efforts of our professors. The ability to grow is the merit of AUSOM. In Kyoung Lim, M.D., Ph.D. Dean Ajou University, School of Medicine Comprising Small Groups Conversations with Mentors is a privilege only AUSOM students are but Offering Diverse Opportunities blessed with. AUSOM students meet with their mentors who have graduated from medical school and work in various fields, including clinicians, med- Conversations With Mentors ical journalists, pastors, and politicians. Learning from their experiences, we are able to establish the directions of our lives and our identities. BT(Bio-Medicine, Bio-Pharmacy) “We dream of diverse futures by conversing with mentors.” After talking to journalists, senators, and social workers who have graduated from medical school, I broadened my dreams. Through conversation with my mentors, I have learned that one does not only become a doctor after graduating from medical schools. Observing the careers of our seniors has helped me decide my career. Joohyun Judith Sim (Entry Class of 2004) >> Comprising Small Groups AUSOM implements a faculty advisor system in which professors counsel but Offering Diverse Opportunities and care for the students in their groups. Each professor is responsible for 4 to 5 students from every class. The system leads to character building, Faculty Advisors encourages academic pursuits, sets routines after graduation, and promotes close personal ties between professors and students. “The human power of AUSOM is created by our students and professors.” As a faculty advisor, I am familiar with my students in their daily lives and activities. In fact, because my students are often too busy doing subject studies and hospital practices to meet frequently, we made a community on the internet for constant exchange. Professor, Ki Hong Chang, M.D., Ph.D. (Department of Obstetrics and Gynecology) >> I get encouraged by counseling with our professors whenever I experience difficulties or worries from studying. Life in medical school can easily become dreary in human relationships due to the heavy amount of studies. But we are fortunate to have such close human relationships. Ji-eun Park (Entry Class of 2002) >> Comprising Small Groups AUSOM is proud of its outstanding educational environment, as well as but Offering Diverse Opportunities its practical education course. Based on the philosophy of providing an Course of Study and Educational Environment ethical medical education, AUSOM strives to mend the problems of Korea’s medical education and to meet the current globalization trends of today’s medicine. BT(Bio-Medicine, Bio-Pharmacy) “To cultivate humane doctors, we aim for a well-rounded medical education.” 3 STEPS OF OUR CURRICULUM Basic Medical Science. 1 We teach primary medical subjects from the 2nd year, and from the 3rd year we teach anatomy and introduce other clinical medical subjects. At the end of the 3rd year, we have the primary medical subjects achievement test to determine the entry qualifications for clinical studies. 2 Clinical Studies. During the 4th year, integrated clinical studies lectures begin and students learn clinical knowledge for each organ and symptom. Sufficient clinical training are given during the 5th and 6th years so that students may learn the basic clinical knowledge and techniques to treat a patient. Medical Humanities and Social Medicine. For a student to learn the mentality and culture of a doctor, subjects such as medical ethics, communication, medical sociology, decision-making, leadership, history of medicine, and medical informatics, as well as English education that is essential in becoming a world leader, are offered throughout the 6 years of education. With 40 students per year, I believe it is my duty not only to train this elite unit of students with medical technology but to raise them as well-educated doctors and medical leaders. The reason why doctors are not so respected despite their high social status is because they lack spiritual attainments. That is why AUSOM cannot neglect education on ethics, culture and art. Professor, Ki Young Lim, M.D., Ph.D. (Head of the Office of Medical Education) >> 3 EDUCATIONAL ENVIRONMENT The cradle of knowledge: Medical Information Searching System The basis of high-tech medical science: lecture and practice rooms Student benefits, scholarship funds and dormitory Medical Information & Media Center | We have 244 data reading seats and about 43,000 medical books. Every year we subscribe to 6100 medical journals and offer various medicine specialized databases. Laboratory for Clinical Education | This is a place where we can try CPX, OSCE and PBL to enhance our abilities. It consists of one monitoring room, 6 practice rooms where we have body models for medical uses very similar to real patients for students to practice performing operation similar to reality. Scholarship funds | We offer various scholarships from a variety of funds in and out of school. CSDL | We have established an educational system call CSDL (Center for SelfDirected Learning), which supplements traditional education methods with online tutoring, class data, exam papers, and educational videos. Lecture halls | This is an automated system that has hightech controlling devices and programs. Professors can simply control sound, images, screen, and curtains by remote controlling devices programmed to auto set circumstances with one touch. Dormitory | Students from the provinces and students with high grades are given priority to the dormitory. 3 out of 4 freshmen are supported by this dormitory system. The dormitory in the hospital is open 24 hours and located on the 3 rd and 4th floor of the hospital annex, which is convenient for students to use. Ajou University Hospital brightens the future of AUSOM such importance to the school. AUSOM students look at the hospital every day and receive new courage as a medical student. Ajou University Hospital stands next to the medical school and is waiting for students who wish to fulfill their dreams as a doctor. “AUSOM is the future of Ajou University Hospital” The level of the medical school determines the level of the hospital. Also, the hospital’s development provides financial aid to the medical school. We are looking forward to the young doctor who will bring glory to Ajou University School of Medicine and Ajou University Hospital. Professor Keehyun Park, M.D., Ph.D. Ajou University Vice President Director of Ajou University Medical Center BT(Bio-Medicine, Bio-Pharmacy) The biggest merit of AUSOM is that the medical school and the hospital are right next to each other. The hospital is of 31 BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) BT(Bio-Medicine, Bio-Pharmacy) Nano Technology NT The New Paradigm of the learning connection & the complex study Ajou University Department of Molecular Science and Technology NT(Nano Technology) What is Nano-medicine? By definition it is the application of the combined technologies of medicine and Nanotechnology. Nano-medicine is a subject in the area of Nanotechnology and more specifically, the area of Nano-biology. Utilizing Nanotechnology, Nano-medicine researches, develops and applies technologies and new materials to diagnose and cure patients at the molecular level. In Korea, Nano-medicine is considered a national project, and thus the nationally-funded BK 21 Program funds research and education in this subject. Most importantly, the ultimate objective of Korea s national Nano-medicine Program is to become one of the leading nations in Nano-medicine. Vision For Nano-medicine as a new emerging technology, Maintain Excellence in Research by converging Nanotechnology & Medicine and Train Top-notch technology specialists to forefront setting technological trends and leading global markets. Goal Professional Training Master 238, Ph. D. 72, Post-doc. 58, Research Professor 28 Nano-medicine World class Research Team Top-notch technology specialists Mission - Cultivate Elite Technologist in Nano-medicine - Formulate Core Research Team in Ajou University - Serve a Hub for Translational Study of Nano-medicine to Industry BK21 Department of Molecular Science and Technology Program Structure International cooperation Programs - Administrates “Active Lecture Programs” - Collaboration opportunities - Shares Patents Education & Research System - Nano/Medical College operated education system - “Participating education” throughout the entire Industrial-Scholar Cooperation System - Strong emphasis on translational research Improvement-based Competition System - Result-based evaluative system - Utilizing the term “Moving Target”, decides strategic areas - Evaluative, and merit-based awarding system International Cooperative Universities Industrial-Scholar Program Research Centers Dept. of Molecular Science and Technology Training Professionals, the world leaders of Nano-medicine Gyeonggi-do Bio-industries Ajou University Medical College & Hospital - Education : Constructs a new paradigm in education, combining nanotechnologies and medicine - Industry : Administrates Cooperative Education Programs and Internships - Administrates Incentive System for technological development >> Trains professionals in Nano-medicine and develops technologies in the field International Cooperative System - Annual review of the program by international advisory committee and external advisory members (professors, and experts from Universities and R&D institutes overseas and in Korea) - International cyber classes, short-term intensive classes headed by professors from the international corporation universities, long-term and short-term exchange research programs with the international corporation universities - Shared Research Projects for Cooperative Learning >> Train Top-notch technology specialists leading the Nano-medicine Improvement-based Competition System - Evaluation policy by MBO for professors and teams achievement annually and operate rewarding system to individual and group. - Through evaluation and competition, achieve a continuous “problem findings and implement” system. - Using the concept of moving target , concentrate efforts and resources on competitive areas for better education and research program. >> Through such a process, our goal is to set up a Program that can burgeon utilizing its full capability NT(Nano Technology) Education & Research System BK21 Department of Molecular Science and Technology Education & Research The Department of Molecular Science and Technology will apply the Nanotechnology acquired from earlier research to medicine and moreover, is formulating a curriculum to industrialize this application. To create a strong research-based program, the Department of MST has framed a curriculum that is connected to three research teams: the Nano Materials research team, the Nanodiagnostics research and development team, and the Nano-therapeutic technology development team. Lastly, the curriculum is designed under the strict guidance of the affiliated professors. Nano-Diagnostics Team -Development of Diagnosis Biosensor/kit -Nano-imaging Diagnosis Technology Development -Diagnostic Body Index Development High-definition Diagnosis Supply of Diagnosis Materials Nano Materials Team -Nano Artificial Body Material Development -Nano-imaging Diagnosis Material Development Development of Nano-medicine -Development of Cell and Cell Activity at the Nano-level Supply Treatment Strategy and Materials Personalized Therapeutics Nano-Therapeutics Team -Cell, tissue Treatment Development -Antibody Treatment Development -Treatment Transfer Development Recruit large Govt. Funding Creation of Social Project or Service BK21 Department of Molecular Science and Technology Education Curriculum Mission of Training Professionals Training of professionals in the field of Nano-medicine Innovated Education Curriculum Innovation of the Education Curriculum - With the technologies and experiences earned from seven years of research and education of the Nano-Biology area, our Program focuses on subjects related to nanotechnology but also, we do have subjects that combine nanomedicine and medicine. - Professors currently doing research on basic and clinical medicine in Ajou University s Medical School have joined the MST department. By doing so, our education curriculum has become based on an education focused on nanomedicine. - The main subjects in this course are nano-medicine basic subjects (medicine, nano-engineering, basic fusion application of nano-medicine to other purposes. Through this, we hope to achieve our goal of training professionals who can change the world. Training Professionals to achieve global competence - Besides the regular subjects required in the course, we have increased classes conducted in English and international programs such as international symposiums, international student and professor exchange programs, and writing English papers. This is because in today s global world, our students must learn English to become true professionals. Education conducted in both the industry and academia - In order to train professionals who can benefit society, we have partnerships with 21 companies, 3 national research centers, and industrial-scholar partnership education programs. Through these partnerships, we hope to train professionals who can start working right away after graduation. - The industrial-scholar partnership education programs are consisted of classes such as industry CEO classes and interdisciplinary technology application classes, internship programs, re-education programs for experts form industries, and programs for training short-term professionals. NT(Nano Technology) techniques), deeper subjects in nano-medicine (diagnosis, treatment, fusion), and lastly, subjects which teach the Nano-Materials Research Team Team Leader Ki-Dong Park Nano Artificial Body Materials Development - Nano-biology treatment material development - Physiology activating material transfer system Affiliated Professors Sang-Youl Kim Han-Sup Uhm Bun-Yeoul Lee Hye-Seong Cho Sang-Wook Kim Yi-Sook Jung Kwang-Yol Kay Suck-Hyun Lee Nano-imaging Diagnosis Materials Development - Develops quantum dot imaging materials - Develops Original Imaging Technology Development of Monitoring the Cell and Cell Activity at the Nano-level - The active state of the cell’s chromosomes and other organs - Cell damage signal index Nano-Materials Research Team Ki-Dong Park, Ph.D. Phone: +82-31-219-2944 (lab), E-mail: kdp@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/ btlab 2000 Present Professor, Ajou University 1991 2000 Principal Research Scientist, Biomaterials Research Center, KIST 1990 1991 Postdoc.Fellow, CCCD, Univ of Utah, .U.S.A 1990 1990 Visiting Scientist, Univ. of Twente, The Netherland 1986 1990 Research Assistant, Dept. of Pharmaceutical Chemistry, Univ. of Utah, U.S.A. The Group for Biomaterials and Tissue Engineering focused on cellular and molecular aspects of biomedical science and engineering, especially, including biomaterials, tissue engineering and drug delivery. Multidisciplinary approaches from the combination of polymer science and biology are focused in this laboratory. Therapeutic aspect as the end point of research and possible human application is considered. The group attempts to develop innovative materials and then to employ them in the study of the biological interactions of interest. Finally, the group strives to demonstrate the potential clinical usefulness of the enabling technology in animal models and then to transfer the technology to commercial concerns for final clinical development. Research Objects Functional polymers for diagnostics and therapeutics; design, synthesis, characterization and in-vitro/in-vivo evaluation of new functional nanobiomaterials for the application of artificial organs, medical devices, tissue engineering and drug delivery system. Theme of Research Research Areas involve that design, synthesis, characterization of new functional polymers for the application of artificial organs , medical devices, tissue engineering and drug delivery; 1) Design and synthesis of biocompatible polymeric materials for therapeutics and diagnostics 2) Tissue/cell compatible materials for tissue engineering 3) Biodegradable polymers for drug delivery system 4) Biomimetic intelligent polymers for cell recognition, biochip, etc. 5) Blood/cell-materials interactions 6) Infection resistant materials for implant devices. 7) Surface modification of polymers and for improved biocompatibility . Publications 1. J.S. Lee, D.H. Go, J.W. Bae, S.J. Lee, K.D. Park, “Heparin conjugated polymeric micelle for long-term delivery of basic fibroblast growth factor”, J. Controlled Release, (2007) 117, 204. 2. H.S. Jang, K.E. Ryu, W.S. Ahn, H.J. Chun, H.D. Park, K.D. Park, Y.H. Kim, “complement activation by sulfonated poly(ethylene glycol)-acrylate copolymers through alternative pathway”, Colloids and Surfaces B. Biointerfaces, (2006) 50(2), 141. 3. C.H. Lee, H.J. Shin, I.H. Cho, Y.M. Kang, I.A. Kim, K.D. Park, J.W. Shin, “Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast”, Biomaterials, (2005) 26, 1261. 4. K.S. Jee, H.D. Park, K.D. Park, Y.H. Kim, J-W Shin, “Heparin conjugated polylactide as a blood compatible materials”, Biomacromolecules, (2004) 5, 1877 NT(Nano Technology) Research area Nano-Materials Research Team Sang-Youl Kim, Ph.D. Phone: +82-31-219-2580, E-mail: sykim@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~ellipso 2000 Present CEO, Ellipso Technology Co. Ltd 1999 Research Professor in Ecole Polytechnique (LPICM) 1993 1994 Visiting Professor in University of North Carolina 1988 Present Assistant, Associate and Full Professor, Ajou University. 1987 1988 Postdoct. Materials Research Laboratory, PSU Optical property ZnS thin films and ZnS+SiO2 thin films prepared by rf sputtering. DLC thin films prepared byPECVD. Simultaneous determination of refractive index, extinction coefficient and void distribution of TiO2 thin films. Silicon dioxide thin films on glass substrate or on c-Si under different growth conditions. Aluminum nitride thin films, AIN/SiO2/c-Si. MNA/PMMA polymer thin film. Polymer-like organic thin films deposited by PECVD using toluene as the precursor. Ge 2Sb 2Te 5 optical recording layer, variation of complex refractive indices with Sb, N concentration change and temperature. Organic thin films. Oxide growth on Si(111) surface using OMA-SE, Complex refractive index of corona poled side-chain NPP polymer. Crystallization behavior of sputter-deposited amorphous Ge2Sb2Te5-(N) thin films. Reversible temperature variation of mask materials for optical super resolution recording. Instrumentation / measurement High speed spectroscopic ellipsometer based on optical multichanel analyzer(OMA-SE). Compact & low end in situ ellipsometer. Fabrication of nanosecond time resolved ellipsometer. Infrared spectroscopic ellipsometer. DUV spectroscopic ellipsometer. A simple polari-metric method for magneto-optical measurement and electro-optic coefficients. Error analysis Error in determining refractive index and thickness of thin SiO2 films using a rotating analyzer ellipsometer. Post-calibration correction of rotating analyzer ellipsometer with optical fiber detection system. Precise Determination of the angle of incidence of spectroscopic ellipsometer. Publications 1. Y-H Kim, S-J Kim, S-Y Kim, S-H Ahn, D-S Seo, J-S Nho, S-M Lee, K-J Kim, W-C Shin, Y-H Kang “Experimental Setup for in Situ Investigation of Phase Changing Behavior in Phase-Change Random-Access Memory Medium by Microfocusing Nanosecond-Time-resolved Ellipsometry”, Japanese Journal of Applied Physics (45, 8A, 64526454), 2006.08 2. M-K Yim, D-H Kim, S-Y Kim, J.E. Bouree “Calculation of the local electric field for an infinite array of conducting nanosized objects”, J. Phys. A: Math. Theor. 2007.01 3. D. Kim, J.E. Bouree, S. Y. Kim “Numerical study on the field emission properties of aligned carbon nanotubes using the hybrid field enhancement scheme”, Appl. Phys. A 83, 2006.01 4. S-Y Kim, S-W Park, H-C Lee, S-J Kim, S-H Ahn “Enhanced Readout signal of Elliptic-Bubble Super Resolution near Field Structure by Temperature-Dependant Complex Refractive index of Phase-Change Medium”, Japanese Journal of Applied Physics (45, 2B, 1390-1393), 2006.02 Nano-Materials Research Team Han-Sup Uhm, Ph.D. Phone: +82-31-219-1970, E-mail: hsuhm@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~plasma 1999 Present Professor of department of MST, Ajou University 2003 2006 Director of Plasma Center, Institute of Advanced Engineering 2006 A Member of Korea Academy of Science and Technology 1978 1999 Scientific Adviser in Plasma Fusion Center, MIT 1978 1985 Executive Scientist in US Naval Surface Warfare Center 1976 1978 Research Professor in University of Maryl Researches on many areas in plasma field, carrying out basic studies related to shooting down of missiles. These researches include (1) charged particle beam propagation, (2) high power microwave generations, (3) neutron propagation, and (4) electrical discharges in high pressure gas and in water. Defense against Biological Weapons A comprehensive decontamination scheme of biological warfare agents, including airborne agents and surface contaminating agents, has been developed. Microwave Plasma Torch A portable microwave plasma torch at atmospheric pressure by making use of magnetrons operated at 2.45 GHz and used in a home microwave oven has been developed. A synthetic tool consisted of the microwave plasma torch has been developed for production of various advanced materials including carbon nano tubes and many metal oxide nano particles. Plasma Display Panel The physical mechanisms of PDP operation have been theoretically modeled and experimentally measured. The theory and experimental data agree reasonably well. Atmospheric Pressure Plasmas We start to develop plasmas in high-pressure chambers where the pressure is 1 atmosphere or greater. This technological research will play a central role in material processing, environmental and energy production industries. Sterilization Sterilization effects of the electrolyzed ozone water were investigated in connection to the cleanup of contaminated areas with biological agents. The electrolyzed ozone water may also be applicable to agriculture, seafood and livestock industries for the preservation of various products as well as being useful in hospitals or other germ infested areas for disinfections. Steam Plasma Torch Injecting steam into a discharge tube as a swirl gas at a temperature higher than 150 , a pure steam torch powered by 2.45 GHz microwaves is generated for various applications like hydrogen production for fuel cells in the future vehicles Publications More than 300 SCI papers in the Applied Physics Letters, the Physics of Plasmas, the Chemical Physics Letters, IEEE Trans. on Plasma Sciences, Langmuir, Thin Solid Films, J. Korean Physical Society, Physical Review Letters, J. of Applied Physics, Jpn. J. of Applied Physics, etc. More than 40 US and Korean Patent registrations. NT(Nano Technology) NT(Nano Technology) Plasma Physics Nano-Materials Research Team Bun-Yeoul Lee, Ph.D. Phone: +82-31-219-1844, E-mail: bunyeoul@ajou.ac.kr, Homepage: www.ajou.ac.kr/~polylab 2001 Present Research Interest Assistant and Associate Professor, Ajou University. 1999 2000 Post doctoral Research Scientist, U.C. Santa Barbara 1995~1999 Senior Scientist, LG Chem. 1. Polymerization Catalysts Single-site transition metal catalysts for polymers have attracted large attention from both academic and industrial research areas. Recently, the conventional Ziegler-Natta catalyst is being substituted by the homogeneous single-site catalysts. New tailor-made plastics with superior properties can be afforded by the homogeneous single-site catalysts. My research is focusing on the development of the novel catalyst by combination of variety of ligands and transition metals. 2. Sustainable Polymer Chemistry utilizing CO2 as a feedstock has drawn considerably attention because CO2 is abundant, inexpensive and nontoxic. Environmental and economical benefits would be great if the polymers derived from CO2 can replace the totally petroleum-derived polymers. Publications 1. Inorg. Chem. 2006, 45, 4228. “Bimetallic Fluorine-Substituted Anilido-Aldimine Zinc Complexes for CO2/(Cyclohexene Oxide) Copolymerization” 2. Organometallics 2006, 25, 2133. “Ortho-Phenylene-Bridged Cp/Amido Titanium Complexes for Ethylene/1-Hexene Copolymerizations” 3. J. Am. Chem. Soc. 2005, 127, 3031. “Bimetallic Anilido-Aldimine Zinc Complexes for Epoxide/CO2 Copolymerization” 4. Angew. Chem. Int. Ed., 2004, 43, 3839. “Dehydroxylation Route to Surface Modification of Mesoporous Silicas Using Grignard Reagents” Nano-Materials Research Team Hye-Seong Cho, Ph.D. Phone: +82-31-219-5052, E-mail: hscho@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~bmbajou/ Research Overview 1995 Present Instructor, Assistant and Associate Professor, Ajou University 2003 2004 Visiting Professor in University of Alberta, Canada 1992 1993 Postdoc fellow, National Institutes of Health, USA Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. One of the primary etiological factors for the development of liver cancer is chronic infection with hepatitis B virus (HBV), and chronic carriers of HBV have a greater than 100-fold increased risk for developing HCC. Molecular and genetic analyses of HCC suggested that chromosome instability plays an important role in liver carcinogenesis. We are currently interested in the molecular mechanisms involved in the regulation of G2 DNA damage checkpoint and mitotic checkpoint regulation that relate to chromosome instability. Organelle biogenesis and its importance in cell cycle has not been discovered. The second goal of our current research is to understand the mitochondria biogenesis during cell cycle. We are currently studying how mitochondrial biogenesis is conducted during cell cycle and division and discovering a link between mitochondria biogenesis and the molecules controlling mitochondria morphology. Our current research is dedicated to the viral oncogenesis by an analysis of the role of HBx viral protein on DNA checkpoint and mitotic checkpoint regulators. In parallel, mitochondria biogenesis and its regulatory mechanism during cell cycle have been exploited using different knockdown models of mitochondria morphology-controlling molecules. Theme of Research 1) Modulation of DNA damage checkpoint & Mitotic checkpoint in liver cancer 2) Antephase checkpoint 3) Cell cycle checkpoint on mitochondria dynamics Publications 1. Sujeong Kim, Hye-Young Kim, Seungmin Lee, Sung Woo Kim, Seonghyang Sohn, Kyongmin Kim, Hyeseong Cho. (2007) Hepatitis B Virus X Protein Mediates Mitochondrial Clustering in Microtubule- and Dynein-dependent Manners. Journal of Virology. 81:1714-1726. 2. Seungmin Lee, Sujeong Kim, Xuejun Sun, Jae-Ho Lee, Hyeseong Cho. (2007) Cell Cycle-dependent Mitochondria Biogenesis and Dynamics in Mammalian Cells. Biochemical and Biophysical Research Communications. 357:111-117. 3. Hae-Ryun Um, Won-Chung Lim, Sun-Young Chae, Sun Park, Jeon Han Park, Hyeseong Cho. (2007) Raf-1 and protein kinase B regulate cell survival through the activation of NF-kB in hepatitis B virus X-expressing cells. Virus Research. 125:1-8. 4. Seungmin Lee, Seon-Yong jeong, Won-Chung Lim, Sujeong Kim, Yong-Yea Park, Xuejun Sun, Richard J, Youle and Hyeseong Cho.(2007) Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence. Journal of Biological Chemistry, in press NT(Nano Technology) Research Objects Nano-Materials Research Team Sang-Wook Kim, Ph.D. Phone: +82-31-219-2522, E-mail: swkim@ajou.ac.kr, Homepage: http://nanomat.ajou.ac.kr 2005 Present Research Overview Assistant professor in Ajou University 2003 2005 Post-Doc. in MIT 1999 2002 Seoul National University, Seoul, Korea, Ph. D. 1991 1993 Seoul National University, Seoul, Korea M. S. in Chemistry 1987 1991 Seoul National University, Seoul, Korea B. S. in Chemistry Our research is focused on the synthesis, characterization, and applications of new nanostructured materials. Especially, we are interested in the synthesis of semiconductor metal-oxide nanocrystals and their applications New NIR emitted Quantum Dot QDs are the materials which show Quantum confinement effect. When the particle size become smaller than the bohr radius, it means distance between electron and hall in the excited state, as the particle size decrease the bandgap become larger. It means absorption and emission of dot changed by their sizes. Some Quantum Dots can emit near-infrared light and we developed new InAsP, InAsSb alloy quantun dots and InP core-shell dots. We applied these Quantum Dots to bio-imaging. Metal-oxide in new Surfactant We developed a new simple surfactants and used them to solubilize metal-oxide and applied to bio imaging Publications 1. Jaeyun Kim, Ji Eun Lee, Jinwoo Lee, Youngjin Jang, Sang-Wook Kim, Kwangjin An, Jung Ho Yu, Taeghwan Hyeon “Generalized Fabrication of Multifunctional Nanoparticle Assemblies on Silica Spheres” Angewante Chemi Int Eds 2006, 45, 4789. 2. John P. Zimmer, Sang-Wook Kim, Shunsuke Ohnishi, Eichii Tanaka, John V. Frangioni, and Moungi G. Bawendi “Size Series of Small Indium Arsenide-Zinc Selenide CoreShell Nanocrystals and Their Application to In Vivo Imaging” J. Am Chem. Soc. 2006, 128, 10526 3. Sang-Wook Kim, John P. Zimmer, Shunsuke Ohnishi, Joseph B. Tracy, John V. Frangioni and Moungi G. Bawendi “Engineering InAsxP1-x/InP/ZnSe III-V Alloyed Core/Shell Quantum Dots for the Near Infrared” J. Am Chem. Soc. 2005, 127, 10526-10532 4. Sang-Wook Kim, Sungjee Kim, Joseph B. Tracy and Moungi G. Bawendi “Phosphine Oxide Polymer For Water-Soluble Nanoparticles” J. Am Chem. Soc. 2005, 127(13) 45564557 Nano-Materials Research Team Yi-Sook Jung, Ph.D. Phone: +82-31-219-5044, E-mail: yisjung@ajou.ac.kr, Homepage: http://www.oldajou.ac.kr/~physio/ 2000~Present Associate Professor, Ajou University. 1996~2000 Postdoct., Ajou University 1988~1996 Researcher, KRICT. 1989 Research fellow, Hoechst AG. Germany Ischemic diseases including myocardial infarction and stroke are the major cause of mortality and disability in the world. Although there are several approaches currently used for the treatment of ischemic disease, such as coronary artery bypass graft (CABG), percutaneous transluminal coronary artery angioplasty (PTCA), and drugs like thrombolytic agent (rt-PA), they still carries a lot of limitations and side effects at the clinical level. Our research interests are focused on the development of new therapeutic target molecules and/or new diagnostic molecules for ischemic heart diseases and ischemic brain diseases. We have been actively collaborating with research institutes such as KRICT, and also industry such as YuYu (Ltd) and Dongbu-Hannong Chemicals (Ltd), with Grants from KFDA, KISTEP, KOSEF, KRF, HPEB, ARPC, and so on. Research Objects Our research area covers cell biology, cell physiology, biochemistry, molecular biology, and in vivo animal study. Research tools and techniques in our study include immunocytochemistry, fluorescence and confocal microscopy, luminometry, western blotting, FACscan analysis, cloning, transfection, microarray, gene fishing, real time PCR in anaerobic cell culture systems and focal ischemic rat and mouse models. Theme of Research 1) Development of novel diagnostic and/or therapeutic targets for ischemic heart disease. 2) Investigation of the roles and signaling mechanisms of the anti-ischemic effect of a novel Na+/H+ -Exchanger inhibitor, KR-33028, in cardiomyocytes and neurons. 3) Investigation of the roles and the regulatory mechanisms of adhesion molecules and junction molecules during ischemia in blood-brain barrier (BBB) in vitro and in vivo. 4) Investigation of the roles and the signaling mechanisms of protein kinase C (PKC) isotypes during ischemia in cardiomyocytes and neurons. Publications 1. Chung SM, Bae ON, Lim KM, Noh JY, Lee MY, Jung YS, Chung JH. Lysophospatidic Acid Induces Thrombogenic Activity Through Phosphatidy Iserine Exposure and Procoagulant Microvesicle Generation in Human Erythrocytes. Arterioscler Thromb Vasc Biol. 32: 414-421. (2007). 2. Kim MY, Kim MJ, Yoon IS, Ahn JH, Lee SH, Baik EJ, Moon CH, Jung YS. Diazoxide acts more as a PKC-e activator, and indirectly activates mitoKATP channel in cardiomyocytes. Br. J. Pharmacol. 149: 1059-70 (2006). 3. Jung YS, Kim MY, Kim MJ, Oh KS, Yi KY, Lee S, Yoo SE, Lee BH. Pharmacological profile of KR-33028, a highly selective inhibitor of NHE. Eur. J. Pharmacol. 535: 220-7 (2006). 4. Park HS, Lee BK, Park S, Kim SU, Lee SH, Baik EJ, Jung YS. Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia. Brain Res. 1061: 67-71 (2005). NT(Nano Technology) NT(Nano Technology) Research Overview Nano-Materials Research Team Kwang-Yol Kay, Ph.D. Phone: +82-31-219-2602, E-mail: kykay@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~oscl 1987~Present Assistant, Associate and Full Professor, Ajou University. 2004 Visiting Professor, Northwestern University 1981~1986 Research Chemist, Max-Planck Institute, Heidelberg, Germany 1977~1979 Research Chemist, Parke-Davis Co., and Ash-Stevens Inc., U.S.A. Research Overview Our research is aimed at synthesizing new classes of molecules with useful and interesting charge-transfer properties. These include mostly organic electroluminescent display(OLED) materials, organic solar cell materials, photoinduced electron transfer and energy transfer materials for artificial photosynthetic reaction centers, and electro-and photoactive materials for molecular electronics. In each area, chemical synthesis is closely linked to a broad array of techniques to elucidate structure, reaction mechanism and bonding. Research Themes 1) Organic Electroluminescent Display Materials Research is directed at the synthesis of OLED materials for blue and red colors with high quantum yield, stability and color purity. For this purpose we synthesize diverse monomeric and polymeric compounds of selected chromophores with diferrent functional group, conjugation length, shape and size. 2) Organic Solar Cell Materials Type A solar cells utilize the photoinduced charge transfer phenomena between conducting polymer(donor) and C 60 derivative(acceptor). To increase photovoltaic efficiency, we synthesize various C60- and perylene derivatives with higher electron affinity and good filmforming property. Type B solar cells(Arakawa system) are dye-sensitized solar cells, and mainly use organic dyes(donor) with an anchoring group(COOH, acceptor) to metal oxide surface. To improve solar to electric conversion efficiency we design and synthesize highly conjugated dyes with absorption of light in the wide range of solar spectrum. 3) Artificial Photosynthetic Reaction Centers To investigate photoinduced electron transfer and energy transfer processes in artificial photosynthetic reaction centers we design and synthesize various electron-donor-acceptor systems with suitable spacer groups. For donor moity we utilize electro- and photoactive chromophores such as metalloporphyrins, phthalocyanines, subphthalocyanines, arylamines and ferrocenes. On the other hand we usually use fullerene(C60) as acceptor moiety in the molecules. Publications 1. M. E. El-Khouly, E. S. Kang, K.-Y. Kay, C. S. Choi, Y. Aaraki, O. Ito “Silicon-Phthalocyanine-Cored Fullerene Dendrimers : Synthesis and Prolonged Charge-Separated States with Dendrimer Generations”, Chem. Eur. J.13, 2854-2863 (2007.03). 2. H. D. Lee, S. K. Oh, C. S. Choi, K.-Y. Kay “A Novel Amphiphilic Re(I) Complex with Bis(fullerene)-Substituted Bipyridine Ligands : Synthesis, Electrochemistry, and Langmuir Film”, Eur. J. Inorg. Chem. 2007, 503-508 (2007.02). 3. K.-Y. Kay et al “Polyphenylbenzene-based organic electroluminescent materials”, Korea Patent 10-0681472 (2007-02-05). 4. K.-Y. Kay et al “Hexabenzocoronene-based OLED materials”, Korea Patent 10-0681473 (2007-02-05). 5. K.-Y. Kay et al “Hexaphenylbenzene-based OLED materials with aminostyryl groups”, Korea Patent 10-0681474 (2007-02-05). Nano-Materials Research Team Suck-Hyun Lee, Ph.D. Phone: +82-31-219-2514, E-mail: hyja@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~polymer/ Research Area and Interest 1981~Present present Professor, Department of Molecular Science and Technology Ajou University 1988~1989 Exchange Professor, University of Connecticut 1) Nonlinear Optical Polymeric Materials The increasing need for high rate signal transmission capabilities, large optical data storage volume and fast optical logic system pushes materials research towards new highly efficient nonlinear optical (NLO) materials with stable and enhanced nonlinear optical response. We have recently discovered that the side-group NLO polymers based on rigid-rod like backbones exhibit the domain structure of chromophores formed after exposing thin films to the corona discharge. The influence of polymer architecture on the domain structure and the long-term stability of the induced polar order is being examined for side-group polymers with various chromophores. Another theme involves the development of the new photorefractive (PR) materials. In collaboration with the optics group, we are presently engaged in work on the molecular design, synthesis, and characterization of novel photorefractive multifunctional polymers. Two-beam-coupling and degenerate four-wave-mixing techniques are used to verify 2) Electrically Conductive Polymers Polyaniline is the continuing to receive high interest in the field of conducting polymers because of its good environmental stability and low cost. Electrically conductive polyaniline can be produced by an oxidative polymerization of aniline. By varying the dopant or type of photonic acids used, conductivity between ca. 10-8-102S/cm may be achieved, which is suitable for many potentially possible applications. Our recent research focuses on the electro spinning technology which uses an electrical force to produce conductive polymer fibers with nanometer-scale diameters. This process produces very highly oriented fibers with large surface areas. There lation ships of fiber orientation to electrical conductivity are areas of prime interest. Publications 1. S-H Lee “Metallic Transport in Polyaniline”, Nature (441, 65), 2006.05 2. J-C Won, S-H Lee “Reversible thermochromism in self-layered hydrogen-bonded polydiacetylene assembly”, Polymer(47,2970), 2006.06 3. O-P Kwon, S-J Kwon, S-H Lee “Layered photoconductive polymers: Anisotropic morphology and correlation with photorefractive reflection grating response”, Journal of Chemical Physics (124,104705), 2006.06 4. D-J Woo, S-H Lee “Styrene/4-Hydroxystyrene Random, Block, and Gradient Copolymers Modified with an Organic Dye: Synthesis by Controlled Radical Polymerization and Characterization of Electrorheological Properties”, Polymer (47, 3287), 2006.03 5. O-P Kwon, S-J Kwon, S-H Lee “Backward beam fanning in organic photorefractive devices”, Appl. Phys. Lett.(89, 021905), 2006.07 NT(Nano Technology) NT(Nano Technology) the non-local nature of the index gratings, and the total grating amplitude, respectively. Nano-diagnostic Research Team Team Leader Jae-Ho Kim Development of Diagnosis Biosensor/kit - High definitive biosensor/ kit development - Array kit for the diagnosis of stomach cancer Affiliated Professors Soo-Han Yoon Sung-Hwa Yoon Hyun-C. Yun Ho-Joon Shin Kyeong-Sook Choi Nano-imaging Diagnosis Technology Development - Development of special biosensor for the search of cancer cells - Using the material research of femto-second light pulse develops treatment of cancer diagnosis Gye-Soon Yoon Sangdun Choi Jong-Soo Lee Diagnosis Body Index Development - Researches the various functions of stomach diseases - Examines the antigen that causes various allergies amongst people Nano-Materials Research Team Jae-Ho Kim, Ph. D. Phone: +82-31-219-2517, E-mail: jhkim@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~raman 2006~Present Chair, Department of Molecular Science and Technology, Ajou University Director, The 2nd BK 21 program of the Molecular Science and Technology in Ajou University. 2001~2005 Associate Dean, College of Engineering, Ajou University 2005~2006 Visiting Scholar, Samsung Advanced Institute of Technology-Samsung Electronics Co. 2005 Visiting Professor, Northwestern University 1994~Present Assistant, Associate and Full Professor, Ajou University. 1990~1992 Staff Scientist, Ames Laboratory-U.S Department of Energy Research Overview The primary goal of our research program is development of new nano-scale materials and surface functionalization to utilize these materials in the areas of biotechnolgy and nano-medicine. For surface functionalization with specifically designed materials either on flat solid substrates or nano-sized surfaces of metal, semiconductors, and inorganic crystal, we use two major techniques for ultra-thin film fabrication; self-assembled monolayer (SAM) and Langmuir-Blodgettt (LB) techniques. For precise control of surface density, structure, orientation and composition of assembled single molecules or nanomaterials on the surface, LB technique has been used in my research projects more than 15 years. To accomplish our goal, extensive instruments for construction and characterization of the surface and interface are established in the our laboratory including SPM, SEM for its morphological observation and FT-IR, Raman spectroscopy polarized optical microscopy, Brewster angle microscopy, fluorescence and UV-vis/NIR spectrometers for chemical composition and structural analysis. Research Objects Our main research effort are concentrated on designing and characterization of the functionalized interface on nano-materials for the Theme of Research Current research topics 1) Development of biosensors: Immobilization and characterization of the bio-materials on the biochip surface for LOC application. 2) Development of fabrication technology for Nanomechanic devices utilizing CNTs and nanoparticles/nanorods : Fabrication of electronic and nano-mechanic devices for SPM, nano ink and patterned multilayered structure with chemically modified and purified CNTs. 3) Development of the bio-compatible dental implant: Surface modification TiO2 dental implant using biomimetic materials to facilitate healing process and to enhance ossteointegration with low bone density patients. Publications 1) S. W. Jang, S. Y. Lee, J. H. Park, J.-H. Kim, D. H. Kwon, S. W. Kang, Light Addressable Potentiometric Sensor Type Penicillin Sensor with SAM and Its Image Detection , Sensors and Materials, (2006) 18(1) 17 2) J.-H. Jang, S.-w. Choi, Y.-G. Kang, C.-J. Lee, J.-H. Kim, Characterization of Self Assembled Thiolated -cyclodextrin and Tolane thioacetate Mixed Monolayer Colloid and Surfaces A, (2005) 257, 31 3) J.-H. Park, J.-H. Park, Z. Yuan, S.-H. Lee, J.-H. Kim, Structural Changes of BODTA Langmuir and LB Monolayers before and after UV Irradiation Colloid and Surfaces A, (2005) 258, 419 4) C. Lee, Y. Kang, K. Seo, Y. M. Shin, J-H. Kim, S-W. Choi, J. Kim, H. M. Soh, H. Lee, H. Kim, C. K. Song, Electronic Transport Through Aromatic Thiol Monolayer Assembled in The Nano Via-hole Electrode Japanese Journal of Applied Physics (2005) 44, 530. 5) M. Lee, W.G. An, J.-H. Kim, H.-J. Choi, S.-H. Kim, M.-H. Han, K. Koh, A Model Study of Artificial Linker System using Self-Assembled Calix[4]arene Derivative Monolayers for Protein Immobilization , Materials Science and Engineering C (2004) 24, 123 NT(Nano Technology) NT(Nano Technology) applications in biosensors and in the area of the nanobio-technology. The metal nanoparticles and quantum dots and metal/semi- conductor nanorods were functionalized by organic linkers, peptides, oligonucleotides for Lab-on-a Chip and prosthetic implants and nano-devises applications. We also design optimized target-specific surfaces for sensor applications, and for prosthetic implants and nano-devises. Nano-Materials Research Team Soo-Han Yoon, M.D. Ph.D. Phone: +82-31-219-5233, E-mail: ee80@ajou.ac.kr, Homepage: Non Available Research interests and areas 2004~Present Professor, College of Medicine, Ajou University 1999~2004 Associate Professor, College of Medicine, Ajou University 1994~1999 Assistant Professor, College of Medicine, Ajou University 1998~1999 Researcher, Department of Neurosurgery, National Institute of Health 1993~1994 Researcher, Department of Neurosurgery, University of Oklahoma 1. Development of modulation or cranifacial orthosis for craniofacial anomaly and positionalasymmetry: We have evaluated postnatal growth of beagle and are developing new concept of craniofacial growth. We also developed cranial fixation devices and are improving its' mechanics. 2. Development of anti-bacterial materials: Development of the new antibiotics or anti-bacterial materials for coating medical instruments. 3. Discovery and development of proaptotic and anti-apoptotic therapeutics in relation of development and senescence: Development of proapoptotic and anti-apoptotic molecules to control development, cancer and senescence. 4. Understanding of hydrocephlaus mechanisms: Development of new therapeutic material for the treatment of hydrocephalus. Publications (corresponding author) 1. Chung J, Sim SY, Yoon SH. Soft-helmet skull remodeling in canine models: intracranial volume unchanged by compensatory skull growth. J Neurosurg 2006;104(5 Suppl):340-7. 2. Park SW, Yoon SH, Cho KG. An endoscopically proven ventriculitis-type, cyst-like intraventricular primary lymphoma of the central nervous system. Acta Neurochirurgica 2006;148(9):981-4. 3. Kim MJ, Yoon SH, Kim SH, Cho KH. Tethered spinal cord with double lipomeningomyeloceles. J Korean Med Sci 2006 Dec;21(6):1133-5. 4. Park SW, Yoon SH, Cho KH, Shin YS, Ahn YH. Infantile lumbosacral spinal subdural abscess with sacral dermal sinus tract. Spine 2007;32(1):E52-E55. 5. Park SW, Yoon SH, Cho KH, Shin YS. Lateral ventricular diverticulum extended into supracerebellar cistern from unilateral obstruction of the foramen of Monro in a neonate case report. Pediatric Neurosurgery 2007;43(2):115-20. 6. Yoon SH, Park SH. Delayed development of frontal mucocele after fronto-orbital advancement in a child with craniosynostosis. Surgical Neurol 2007;67(5):517-21. 7. Park SW, Yoon SH, Cho KH, Shin YS. Valve pressure upgrade may produce progressive deterioration of vision in children with slit ventricle syndrome. Pediatric Neurosurgery (in press) 8. Sim SY, Shin YS, Yoon SH. Endovascular internal trapping of traumatic pericallosal pseudoaneurysm with hydrogel-coated self-expandable coil in a child: a case report. Surgical Neurol (in press) 9. Lee JA, Park DH, Yoon SH, Chung Jaiho. Distractor breakage in cranial distraction osteogenesis for children with craniosynostosis. Pediatric Neurosurgery (in press) Nano-diagnostic Research Team Sung-Hwa Yoon, Ph.D. Phone:+82-31-219-2515, E-mail: shyoon@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~fchem 1999~Present Professor Department of Applied Chemistry Ajou University 1994~1999 Associate professor Department of Applied Chemistry Ajou University 1990~1994 Assistant professor Department of Applied Chemistry Ajou University 1989~1990 Postdoctoral Fellow Center for Drug Discovery University of Florida 1986 Adjunctive Research Scientist Key Pharmaceutical Company Alachua, Florida USA Since the development of approaches and technologies for the discovery of new therapeutic drugs is very important for better human health, our research focuses on finding new tools and methods for improving the success rate of drug discovery and development. The focus has been on targeting neuroprotective agents for the treatment of neurodegenerative diseases such as stroke, Parkinson's disease, and Alzheimer's disease. In order to perform the research efficiently, our research team collaborates with other biological research teams, and interacts with the pharmaceutical and biotechnological industries in our area. Research Objects Design and synthesis of novel therapeutic agents In order to find new therapeutic agents for the treatment of target diseases, we first investigate the structure-activity relationship of various series of compounds on the basis of retro metabolic design. Then, we optimize the phamacokinetic properties of the lead compound and develop a new candidate for drugs. During this work, we collaborate with the research team for biological evaluations of the compounds. Theme of Research CB1 receptors, which are abundant in mammalian tissue, specially in human, are highly expressed in the central nerve system. They exist in post synaptic neuron and modulate neurotransmitter release. Therapeutic target of these receptors is pain, obesity and osteoporosis. As a part of a program for developing new anti-obesity agents, we have investigated the structure-activity relationship of carbamate derivatives for the purpose of increasing the selectivity of an antagonistic cannabinoid receptor-1 (CB1 receptor) over an antagonistic cannabinoid receptor-2 (CB2 receptor). Publications 1. H-S Moon, S-I Nam, S-D Kim, D-Y Kim, B-J Gwag, Y-A Lee, and S-H Yoon. “Structural Requirements for the Neuroprotective Effects of Aspirin Analogues against NMDA and Zinc Ion Neurotoxicities”.J.of Pharmacy and Pharmacology.54(7), 935-944 (2002). 2. J Wu, S-H Yoon, W-M Wu, and NBodor “SynthesisandBiologicalEvaluationsofBrainTargetedChemicalDeliverySystemsof[Nva2]-TRH” .J.of Pharmacy and Pharmacology. 54(7),945-950 (2002). 3. B-J Gwag, Y-A Lee, S-Y Ko, M-J Lee, D-S Im, H-R Lim, S-M Park, H-Y Byun, S-J Son, H-J Kwon, J-Y Lee, J-Y Cho, S-J Wob, K-W Kim, Y-M Ahn, H-S Moon, H-U Lee, S-H Yoon, J-H Noh, J-M Chung, S-I Cho. “Marked prevention ischemic brain injury by Neu2000, NMDA antagonist ant antioxidant derived from aspirin and sulfasalazine” Journal of Cerebral Blood Flow and Metabolism,. In press (2007) NT(Nano Technology) NT(Nano Technology) Research Overview Nano-diagnostic Research Team Hyun C. Yoon, Ph.D. Phone:+82-31-219-2512, E-mail: hcyoon@ajou.ac.kr, Homepage: www.ajou.ac.kr/~bionano 2003~Present Assistant, Associate Professor, Ajou University 2001 - 2003 Senior Research Scientist, ETRI 2000 - 2001 Postdoctoral Fellow, KAIST Biosensors & Nanobiochip Technology In the research fields of clinical analysis and bioanalytical sciences, there has been an ever increasing demand for efficient analytical tools. Therefore, a scientific field, linking bioanalytical techniques with microelectronics technology has been emerged and expanded. Especially, biochip technology including immuno- or affinity-sensing, registering biospecific interactions such as antigen-antibody, ligand-receptor and protein-protein recognition reactions, is under great demand in terms of assay automation and multiplexing. The recent completion of human genome sequencing and flourishing genomics/proteomics have opened new research fields of high throughput analysis with easy access, making the development of biosensing techniques more significant. Current research trends in biosensors or biochips area mainly include two directions. First one is the design and fabrication of biorecognition interfaces having desired characteristics such as surface functionality, immobilization density, biocompatibility, inertness to nonspecific binding. Second is the introduction of new signal generation techniques, particularly emphasizing multiplexed analysis with array-type sensors and automation. We have been working on the development of technologies that uses dendrimers as the building unit for the biospecific recognition layers and signaling strategies by using bioelectrocatalysis. Currently, we are aiming to integrate biosensing technologies with microfabrication processes in a form of protein chip microsystem and lab-on-a-chip. Publications 1. Microfluidic chip accomplishing self-fluid replacement using only capillary force and its bioanalytical application, Kwang Hyo Chung, Jung Woo Hong, Dae Sik Lee, and Hyun C. Yoon, Analytica Chimica Acta, 585 (2007) 1-10. 2. A new immunosensing method by galactose oxidase-mediated electrocatalysis using a virtual beaker array, Sung Il Jeon, Jung Woo Hong, and Hyun C. Yoon, Biotechnology Letters, 28 (2006) 1401-1408. 3. Bioelectrocatalytic signaling from immunosensors with back-filling immobilization of glucose oxidase on the biorecognition surfaces, Byoung Yeon Won, Hyoung Gil Choi, Kong Hwan Kim, Sang Yo Byun, Hak-Sung Kim, and Hyun C. Yoon, Biotechnology and Bioengineering, 89 (2005) 815-821. 4.Multichannel surface plasmon resonance imaging and analysis of micropatterned self-assembled monolayers and protein affinity interactions, Hyeon-Bong Pyo, Yong-Beom Shin, Min-Gon Kim, and Hyun C. Yoon, Langmuir, 21 (2005) 166-171. Nano-diagnostic Research Team Ho-Joon Shin, Ph.D. Phone:+82-31-219-5076, E-mail: hjshin@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~microbio Pathogenic amoebae 1995~Present Professor, Chairman in Department of Microbiology, School of Medicine, Ajou University 1994~1995 Post-Doc. Department of Zoology, Tennessee University(US) 1990~1994 Research Fellow, Department of Parasitology, Yonsei University Pathogenic and antigenic gene cloning from pathogenic amoebae, Naegleria fowleri, and massive production of recombinant proteins from cloned genes have been carried out. Characterization of selected recombinant proteins has been performed for diagnostic or therapeutic usage. And then, the cellular and protective immunity of mice infected with N. fowleri have been carried out. Mite causing asthma Antigenic gene cloning from mite causing asthma has been carried out. Recombinant proteins from cloned genes has been produced and characterized for diagnostic or therapeutic usage. And antibody has been produced with the recombinant antigens and will be treated in patients. Hybridoma cell lines producing the monoclonal antibody for malaria LDH (lactase dehydrogenase) has been produced by cell fusion technique, and their antigenecity has been characterized by the sandwich ELISA method. Deep-stick diagnostic kit for malaria infection has been developed by using the cloned monoclonal antibodies, and the sensitivity and specificity of kit have been tested. The kits will be applied on the detection of malaria patients. Publications 1. Jeong SR, Lee SC, Song KJ, Park S, Kim K, Kwon MH, Im KI, Shin HJ. Expression of the nfa1 gene cloned from pathogenic Naegleria fowleri in nonpathogenic N. gruberi enhances cytotoxicity against CHO target cells in vitro. Infect Immun, 73(7):4098-4105, 2005 2. Kang SY, Song KJ, Jeong SR, Kim JH, Park S, Kim K, Kwon MH, Shin HJ. Role of the Nfa1 protein in pathogenic Naegleria fowleri co-cultured with CHO target cells. Clin Diagn Lab Immunol, 12(7): 873-876, 2005 3. Oh YH, Jeong SR, Kim JH, Song KJ, Kim K, Park S, Sohn S, Shin HJ. Cytopathic changes and pro-inflammatory cytokines induced by Naegleria fowleri trophozoites in rat microglial cells and protective effect of an anti-Nfa1 antibody. Parasite Immunol, 27:453-459, 2005 4. Song KJ, Jeong SR, Park S, Kim K, Kwon MH, Im KI, Pak JH, Shin HJ. Naegleria fowleri: Functional expression of the Nfa1 protein in transfected Naegleria gruberi by promoter modification. Exp Parasitol, 112:115-120, 2006. 5. Song KJ, Song KH, Na BG, Kim JH, Kwon D, Park S, Pak JH, Im KI, Shin HJ. Molecular cloning an characterization of a cytosolic heat shock protein 70 from Naegleria fowleri. Parasitol Research, 100:1083-1089, 2007. NT(Nano Technology) NT(Nano Technology) Malaria Nano-diagnostic Research Team Kyeong-Sook Choi, Ph.D. Phone: +82-31-219-4552, E-mail: kschoi@ajou.ac.kr 1997~Present Instructor, Assistant and Associate Professor in Institute for Medical Sciences, Ajou University School of Medicine Major Cancer Biology Research interest 1) Development of the strategies to induce cell death selectively in cancer cells 2) Development of the strategies to overcome apoptotic resistance in cancer cells 3) Signaling pathways involved in cell death (apoptosis, cell death through mitotic catastrophe, autophagic cell death, necrosis etc.) 4) Biochemical differences between cancer and normal cells Publications 1. EH Kim, S Sohn, HJ Kwon, SU Kim, MJ Kim, SJ Lee, KS Choi “Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells”, Cancer Res 2007 (in press) 2. H Kim, EH Kim, YW Eom, WH Kim, TK Kwon, SJ Lee, KS Choi “Sulforaphane sensitizes TRAIL-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res 2006;66:1740-50 3. EH Kim, HS Kim, SU Kim, EJ Noh, JS Lee, KS Choi “Sodium butyrate sensitizes human glioma cells TRAIL-mediated apoptosis through inhibition of Cdc2 and subsequent downregulation of survivin and XIAP” Oncogene 2005;24:6877-89 4. YW Eom, MA Kim, SS Park, MJ Goo, HJ Kwon, S Sohn, WH Kim, G Yoon, KS Choi. “Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene 2005;24:4765-77 5. EH Kim, SU Kim, KS Choi “Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP” Oncogene 2005;24:838-49 Nano-diagnostic Research Team Gye-Soon Yoon, Ph.D. Phone: +82-31-219-5054, E-mail: ypeace@ajou.ac.kr, Homepage: http://www.mitochondria.co.kr 2000~Present Full-time Instructor, Assistant and Associate Professor, Ajou U. 1999~2000 Research Fellow, Ajou University School of Medicine 1996~1999 Post-Doctoral Fellow, Yonsei University. 1992~1996 Research Associate, Oklahoma State University Mitochondria play a pivotal role as ATP generator in aerobically growing cells. Another characteristic of mitochondria is its dynamic property exhibiting diversity of their distribution and number, and plasticity of their morphology in eukaryotic cells. For several years, we have developed diverse cellular senescence and cellular transformation systems which harbors progressive functional defects of mitochondria. By employing these systems, we try to elucidate the mecha nisms involved in the mitochondrial dysfunction accompanying their dynamic changes in detail and to understand how the cells survive despite of the defects by investigating cellular defenses against the defects by employing several. We are especially focusing on elucidation of critical factors regulating mitochondrial biogenesis and morphogenesis, and metabolic changes under diverse metabolic stresses. Research Objects Although mitochondrial dysfunction has long been implicated in many degenerative diseases including aging and cancer, the underlying mechanisms remain unclear. The aim of our study is to elucidate the mechanisms involved in changes in mitochondrial biogenesis, such as functional defects, morphological changes, cellular number, and distribution, and to elucidate cellular defense systems occurring in the process of aging and carcinogenesis. We can provide new targets to develop protective and therapeutic agents for aging and cancer. Research Area and Interest 1) Regulation of metabolic function, biogenesis, and morphogenesis of mitochondria in the process of cellular senescence and cellular transformation 2) Effects of mitochondrial defects on cellular function and cell cycle progression 3) Metabolic switch accompanied with mitochondrial defects Publications 1. Formation of elongated giant mitochondria in DFO-induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1. (2006) J. cell. Phys. 209: 468-480. 2. Direct activation of TGF-beta1 transcription by androgen and androgen receptor complex in Huh7 human hepatoma cells and its tumor in nude mice. (2006) J. Cell Biochem. 97: 393-411 3) TGF 1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lu cells. (2005) Oncogene 24:1895-1903. 4. Mitochondrial dysfunction via disruption of complex II activity during iron chelation-induced senescence-like growth arrest of Chang cells. (2004) Annals NY Acad. Sci. 1011, 123-132. 5. Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest. (2003) J. Biol. Chem. 278, 51577-51586. NT(Nano Technology) NT(Nano Technology) Research Overview Nano-diagnostic Research Team Sangdun Choi, Ph.D Phone: +82-31-219-2600, E-mail: sangdunchoi@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~schoi 2006~Present Associate Professor, Ajou University, Korea 1997~2006 Transcription Analysis Lab Director, California Institute of Technology, USA 2000~2006 Lead Scientist, Alliance for Cellular Signaling, USA Research Overview The research in my laboratory involves deciphering complex signaling systems and control networks using immune cells and neuronal cells. Complex biological phenomena can be understood in terms of the interactions of functioning components, and network perturbations and the measurement of cellular responses can be used to probe connectivity and signaling system function. Research Objects We have analyzed transcriptional (using DNA microarrays) and cytokine changes after the addition of a single (about 60 including 2MA, Anti-Ig, C5a, CD40L, CpG, IFNa, IFNb, IFNg, IL1b, IL4, IL6, IL10, ISO, KDO, LPS, PGE2, PolyIC, S1P, Taxol, TNFa, Zymosan, etc) or multiple ligands (2MA, 8BR, IFNb, IFNg, IL6, ISO, KDO, LPS, PGE2, TGFb, etc) in mouse B cells and macrophages. A time series examining the combinational effects of endogenous or exogenous ligands enabled identification of the signal networks causing crosstalk effects related to Toll-like receptors (TLR), G protein coupled receptors (GPCR), and others. We have also examined the effectiveness of RNA interference (RNAi) methodology using macrophage cells transfected with lentiviral small hairpin RNA (shRNA), small interfering RNA (siRNA) or antisense oligonucleotide in order to further develop RNAi as a gene knockdown tool. Theme of Research Biological processes are driven by complex systems of functionally interacting macromolecules. Systems biology combined with molecular biological tools is ideal for the identification of the genes involved in these processes and the description of the signaling pathways that regulate them. Publications 1. A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies (2006) Nature Biotechnology. 24(7):832-40 2. Enhanced efficacy and duration of RNAi using synthetic RNA duplexes that are substrates for Dicer (2005) Nature Biotechnology. 23(2):222-226 3. The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome (2004) Science. 304(5668):304-307 4. Unravelling the signal-transduction network in B lymphocytes (2002) Nature 420:708-710 5. Overview of the Alliance for Cellular Signaling (2002) Nature 420:703-706. 6. Initial sequencing and analysis of the human genome (2001) Nature 409:860-921 Nano-diagnostic Research Team Jong-Soo Lee, Ph.D. Phone: +82-31-219-1886, E-mail: jsjlee@ajou.ac.kr, Homepage: http://ajou.ac.kr/~mcmb 2005~Present Assistant Professor, Ajou University 2001~2005 Senior Principal Investigator, Department Chief, National Cancer Center 1999~2001 Research Professor, Hanyang University 1995~2000 Research Fellow, National Institutes of Health, USA 1992~1995 Researcher, Molecular Microbiology Research Center, Seoul National University To elucidate molecular mechanisms for genomic and epigenomic dynamics during carcinogenesis or differentiation in mammals, our research focuses on mechanisms maintaining genomic integrity as well as governing development of cancer or senescence as a consequence of external/internal genomic damages. In particular, a major area of our interest is how mammalian cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA damage, signaling pathways are rapidly activated and proteins are recalled to form functional protein network. These pathways and networks lead to cellular responses such as cell cycle arrest via checkpoint pathways, DNA repair, transcriptional programming and apoptosis in dealing with the damage. In contrast, failure to do these can result in genomic instability and deadly fatal cancer in human, because alterations of DNA are not repaired but accumulated in cancers and senescence. Research Area and Interests 1) DNA damage response- We are studying how DNA damage signal is transduced and how the transduced signal controls DNA damage response, including cell cycle checkpoint, DNA repair, transcriptional remodeling, and apoptosis. Also, we are studying functional protein network that is generated following DNA damaging. 2) Epigenetics throughout development and carcinogenesis- Also, epigenomic instability occurs during cancer development. Thus, we have a hypothesis that epigenomic instability occurs as one of multi-stage of carcinogensis and senescence and relates to genomic instability somehow. We are studying how epigenomic instability is triggered and affects geomic instability or vice versa. Methods and Techniques Cell biology-, Molecular biology-, Cancer biology-, Imaging-, Biochemical- and many other methods are used for studies. Publications 1. Cancer Research. 2005. 65(24); 11400-11410 2. EMBO Reports. 2005. 6(10); 949-955 3. Oncogene 2005. 24(46); 6877-89 4. Oncogene 2004. 23(9); 1724-1736 5. Nucleic Acid Research. 2007. in press NT(Nano Technology) NT(Nano Technology) Research Overview Nano-Therapeutic Research Team Team Leader Byoung-Hyun Min Affiliated Professors Jae-Ho Lee Cell, Tissue therapeutics Development - Stem cell differentiation development technology - Using nano-materials, tracks down certain cells - Transplantation of nano-carrier to cells - Using nano-maintenance material, creates artificial tissues Young-Don Lee Gwang Lee Yeon-Woo Ryu Yong-Sung Kim Sang-Yo Byun Sang-Wook Han Antibody Therapeutics Development - Develops anticancer antibody treatment - Inclination of the treatment of target cells through antibodies - Long-term release transfer system Pyung Cheon Lee Nano-diagnostic Research Team Byoung-Hyun Min, MD., Ph.D. Phone: +82-31-219-5225, E-mail: bhmin@ajou.ac.kr, Homepage: http://www.cellntissue.com 2006~Present Professor, Department of Molecular Science and Technology, Ajou University 2004~Present Department of Orthopedic Surgery, Ajou University School of Medicine 1987~1988 Director in Cell therapy center, Director in Biomedical Engineering Center 1994~1995 Fellowship in Pacific Rim Fellowship Program, Southern California, Center for Sports Medicine The Cell Therapy Center (CTC) was founded in sept. 2005 at Ajou university Medical Center as a Contact Manufacturing Organism (CMO). The CTC aim is the development of cell therapies and cell regeneration technology using autologous and allognious cell transplantation for treatment of degenerative arthritis and other incurable diseases such as alzheimers, cardiac infarction, cerebral haemorrhage diseases. Investigators at the CTC therefore identify the therapeutic potential of in vitro cultured cells. Research Objects 1. Stem cell biology The study of chondrogenic differentiation of mesenchymal stem cells derived from bone marrow and cord blood. 2. Low intensity ultrasound (LIUS) application chondrogenic differentiation 3. Tissue engineering Fabrication of biomembrane for stimulation of wound healing 4. Cartilage biology Development of new chondrogenic marker in vitro Theme of Research Current Research 1. Development of cell therapies for cartilage regeneration 2. Establishment of cell therapy and tissue engineering technology concerned to cartilage repair 3. Application of these technologies to study other cell therapies 4. Lead of domestic and international cell therapy markets Publications 1. Park S-H, Sim WY, Park SW, Yang SS, Park SR, Park KD, Min B-H. An electromagnetic compressive force by cell exciter stimulates chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Tissue Eng. 2006; 12(11):3107-17. 2. Cui JH, Park KD, Park SR, Min B-H. Effects of low intensity ultrasound on chondrogenic differentiation of mesenchymal stem cells embedded in polyglycolic acid-an in vivo study. Tissue Eng. 2006; 12(1): 75-82. 3. Cui JH, Park SR, Park K, Choi BH, Min B-H. Preconditioning of mesenchymal stem cells with low-intensity ultrasound for cartilage formation in vivo. Tissue Eng. 2007; 13(2): 351-60. 4. Lee HJ, Choi BH, Min B-H, Park SR. Low-intensity ultrasound inhibits apoptosis and enhances viability of human mesenchymal stem cells in three-dimensional alginate culture during chondrogenic differentiation. Tissue Eng. 2007; 13(5): 1049-57. NT(Nano Technology) NT(Nano Technology) Research Overview Nano-Therapeutic Research Team Jae-Ho Lee M.D., Ph.D. Phone: +82-31-219-5053, E-mail: jhlee64@ajou.ac.kr, Homepage: http://www.ajou.ac.kr/~bmbajou/ 2003~2007 Chairperson, Dept. of Biochemistry and Molecular Biology, Ajou University School of Medicine 2002~Present Associate professor 1998~2000 Senior post-doctoral fellow in ABL-FCRDC 1997~2001 Assistant professor in Dept. of Biochemistry and Molecular Biology, Ajou University School of Medicine Research Overview Hepatocyte growth factor (HGF) and its receptor, c-Met, play an important role in human carcinogenesis and cancer progression. We selected HGF/c-Met signaling as a promising molecular target for the development of new therapeutics against human tumor, and have performed researches to understand basic mechanisms as well as to apply those knowledges in developing new therapeutics. In addition, we are also trying to develop anti-fibrotic therapeutics using HGF. These target-oriented approaches are accompanied with the more basic research on cancer stem cell and cell cycle machinery. Research objective Development of useful therapeutics against human tumors and fibrotic diseases through understanding of basic mechanisms underlying those diseases especially in terms of the role of HGF/c-Met signaling. Research Area and Interest 1. Role of the variant of c-Met We found a novel alternative splicing form of c-Met with inhibitory role in HGF/c-met signaling, d13-Met, from human tissues. We are now addressing its role in normal skeletal muscle differentiation process as well as in rhabdomyosarcomagenesis. 2. Influence of aberrant growth factor signaling on cell cycle We found G2-delaying effect of HGF as well as its effect on genomic instability. We are working to provide the mechanistic explanation on this observation. 3. HGF as an anti-fibrotic agent Approaches to use HGF as a therapeutic in cirrhosis are also under development. 4. Therapeutic intervention targeting HGF/c-Met signal We are focusing to find a small molecular inhibitor from the extracts of Ephedra sinica. In addition, we are focusing on the development of various vehicles for gene therapy of human cancers. Publications 1. Yoon YS et al. TGF beta-1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lucells.Oncogene. 2005 Mar 10;24 (11):1895-903 2. Park M et al. Presence of autocrine hepatocyte growth factor-Met signaling and its role in proliferation and migration of SNU-484 gastric cancer cell line. Exp Mol Med. 2005 Jun 30;37(3):213-9. 3. Lee JH et al. An alternatively spliced form of Met receptor is tumorigenic. Exp Mol Med. 2006 Oct 31;38(5):565-73. 4. Yun Yoen Park et al. Hepatocyte Growth Factor at S phase Induces G2 Delay through Sustained ERK Activation. Biochem Biophys Res Commun. 2007 Apr 27; 356(1):300-5 Nano-Therapeutic Research Team Young-Don Lee, Ph.D. Phone: +82-31-219-5031, E-mail: ydl1217@ajou.ac.kr, Homepage: http://neuron.ajou.ac.kr 2006~Present Professor, Department of Molecular Science Technology, Graduate School of Ajou University 2004~Present Director, Center for Cell Death Regulating Biodrug (GRRC) 1989~Present Assistant, Associate, and Full Professor, Department of Anatomy, School of Medicine, Ajou 2000~2001 Visiting Professor, Osaka University, Japan 1994 Department of Biochemistry, Yonsei University University Research Overview The studies performing in Neurodevelopment and Stem Cell Lab. provide the scientific knowledge of future stem cell therapy for various neurodegenerative diseases on the basis of deep understanding on the cellular mechanism of neuronal differentiation. Research fields in the Lab are mainly focused to following subjects; 1) Development of stem cell therapy for various incurable neurodegenerative diseases, 2) Search for lead compounds to prevent neuronal cell death from natural products, 3) Cellular mechanism of neural stem cell differentiation during brain development. Research Themes Morphological analysis using histological and cytological methods / In vivo and in vitro gene transfer into cells or tissues / Cell and tissue culture / General works in genetic engineering and biochemistry / Animal studies using mutants and disease models Publications 1. Compartmentalization of protein kinase A signaling by the heterotrimeric G protein Go. Proc Nat Acad Sci USA, 103:19158-19163, 2006 2. Modulation of the N-type calcium channel gene expression by the alpha subunit of Go. Mol Brain Res 112(1-2): 95-102, 2003 3. Apolipoprotein-E and Reelin ligands modulate tau phosphorylation through an Apolipoprotein-E receptor/Disabled-1/Glycogen Synthase Kinase-3beta cascade. FASEB J 17:295-297, 2003 4. Apolipoprotein E4 stimulates cAMP response element binding protein transcriptional activity through the extracellular-regulated kinase pathway. J Biol Chem 276(5):30463053, 2001 NT(Nano Technology) NT(Nano Technology) Research Methods 1) Regulation of cell fate of stem cells using genetic modification 2) Development of effective tools for isolation of pure stem cells using reporter vectors 3) Evaluation of efficacy of stem cell transplantation in disease animal models 4) Crosstalk of ApoE signaling with other pathway in neuronal cell death 5) Search for pharmacologically active substances preventing neuronal cell death. 6) The role of reelin-dab1 signaling in neuronal migration and cell fate determination Nano-Therapeutic Research Team Gwang Lee, Ph.D. Phone: +82-31-219-4554, E-mail: glee@ajou.ac.kr Homepage: http://wwwold.ajou.ac.kr/~inst/lab/lab_01.php?idx=000000027 Research Overview 2001~Present Assistant Professor, Ajou University. 1999 - 2001 Postdoct. NINDS/NIH, MD, U.S.A. Our main research is to develop and monitor autologous human mesenchymal stem cell(hMSCs) as the potential to aid functional recovery in neurological disease. hMSCs have recently been investigated as an attractivetherapeutic tool for ischemic stroke and myocardial infarction because of their plasticity and availability. Following stroke in a rat model, hMSCs were reported to ameliorate functional deficits by secreting neurotrophic factors, which reduce apoptosis and promoteendogenous cellular proliferation. Our stem cell therapy research will provide useful information for the considering hMSCs using a potential source of stem cell-based direct transplantation in brain disease. Research Objects Our research projects are focused on the development of pharmaceutical cells that were treated in neurological diseases by using autologous hMSCs and the biochemical monitoring of the therapeutic effects of hMSCs transplantation by using GC/MASS and Tandem/MASS. Theme of Research Current research topics 1. Enhancing the efficacy of human mesenchymal stem cells in neurological diseases. 2. Development of a novel adenosine deaminase inhibitor, IADA-7 3. Finding the role of synphilin-1 which is a key modulator of alpha-synuclein in dopaminergic neurons. Publications 1. Lee G, Tanaka M, Park K, Lee SS, Kim YM, Junn E, Lee SH, Mouradian MM.(2004). Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin1interaction and inclusion body formation. J Biol Chem. 20;279(8):6834-9. 2. Bang OY, Lee JS, Lee PH, Lee G. (2005). Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 57(6):874-82. 3. Paik MJ, Park KH, Park JJ, Kim KR, Ahn YH, Shin GT, Lee G. (2007). Patterns of plasma fatty acids in rat models with adenovirus infection. J Biochem Mol Biol. 40(1):119-24. 4. Paik MJ, Lee KA, Jeong R, Kim KR, Park CS, Ahn YH, Lee G. (2007). Pattern recognition analysis of polyamines in the plasma of rat models with adenovirus infection. Clin Chim Acta. 380:228-231 Nano-Therapeutic Research Team Yeon-Woo Ryu, Ph.D. Phone: +82-31-219-2449, E-mail: ywryu@ajou.ac.kr, Homepage: www.ajou.ac.kr/~fereng Research Overview 2005~Present Chair, Division of Biotechnology & Nanotechnology 1980~present Assistant, Associate and Full Professor, Ajou University 1985~1987 Visiting Professor in University of California, Davis Over the past several decades, intensive researches of biotechnology including fermentation, metabolic, genetic and protein engineering have been resulted in tremendous progress. Our research efforts are focused on development of the strains that produce valuable products with high yield and optimization of fermentation that can directly applied to industrial production. Ultimate goal of our research is construction of knowledge as a bridge between research laboratory and industry. Research objects Screening and design of microbial strains : We have developed microbial strains via genetic, metabolic and protein engineering to obtain the strain which can produce valuable products with proper form and high productivity. Optimization and development of fermentation process : We optimized fermentation process of developed strain for high yield production via optimization of fermentation medium, culture Theme of Research Characterization of S-adenosylmethionine (SAM) : SAM is the main methyl donor in all kinds of organisms and plays important roles in gene silencing, protein methylation and cell membrane fluidity. We are investigating that effect of higher SAM production to the production and secretion of valuable products as antibiotics (avermectin) in streptomyces. Coenzyme Q10 production : Coenzyme Q10 is a vitamin-like substance that is used in the treatment of a variety of disorders primarily related to suboptimal cellular energy metabolism and oxidative injury. Genetic and metabolic engineering has been applied to develop the strain that can carry out the higher coenzyme Q10 production. Also we are performing large quantity production of coenzyme Q10. Characterization of esterase : We obtained a metogenomic library constructed from various environmental soils to isolate a new ester-hydrolyzing enzyme via catalytic activity-based screening. Also we have performed to develop the strain contains esterase with high thermostability for higher productivity. Publications 1. Gi-Sub Choi, Yong-Sung Kim, Jin-Ho Seo, and Yeon-Woo Ryu. Restricted electron flux increases coenzyme Q10 production in Agrobacterium tumefaciens ATCC4452. Process Biochemistry, 40(10), 3225-3229 (2005) 2. Yun-Jung Kim, Gi-Sub Choi, Seung-Bum Kim, Gee-Sun Yoon, Yong-Sung Kim, and Yeon-Woo Ryu. Screening and characterization of a novel esterase from a metagenomic library. Protein Expression and Purification, 45(2), 315-323, (2006). 3. Gee-Sun Yoon, Kwon-Hye Ko, Hyun-Woo Kang, Joo-Won Suh, Yong-Sung Kim and Yeon-Woo Ryu. Characterization of S-Adenosylmethionine Synthetase from Streptomyces avermitilis NRRL8165 and Its Effect on Antibiotic Production. Enzyme and Microbial Technololy, 39(3), 446-473, (2006) 4. Mi-Sun Ahn, Seung-Bum Kim, Mi-Ra-Kang, Yeon-Woo Ryu, and T. Doo-Hun Kim. Chaperone-like activities of -synuclein: -Synuclein assists enzymatic activities of esterases. Biochemical and Biophysical Research Communications, 346(4), 1142-1149 (2006) NT(Nano Technology) NT(Nano Technology) condition and processes. Nano-Therapeutic Research Team Yong-Sung Kim, Ph.D. Phone: +82-31-219-2662, Email: Kimys@ajou.ac.kr, Homepage: www.ajou.ac.kr/~bioeng/ Research Overview 2004~Present Assistant Professor in Ajou University 2002~2004 Research Associate, MIT 1999~2002 Ph. D., U of Colorado Health Sciences Center 1996~1998 M.Sc., Dept. of Biological Sciences, KAIST 1990~1996 B.Sc., Dept. of Food Science and Technol. SNU. Biological engineering is a promising and demanding field of academic research and an industrial practice that deals with biomolecules and biomolecular processes to create and discover new high-value biomolecules. Our research interests are antibody and protein engineering for the discovery and development of new protein pharmaceuticals. Through comprehensive understandings of biomolecular processes (e.g., receptor-ligand/receptorreceptor interactions, molecular signaling networks, intracellular protein-protein interactions) underlying many human diseasesat the molecular level, drugable proteins can be identified, targeted and engineered to have desirable properties, such as high affinity, improved stability, high specificity, no cytotoxicity, and improved pharmacokinetics. Our research tools are hypothesis-driven rational protein design as well as protein engineering by directed-evolution combined with high throughput screening. For HTS, we are using yeast surface display adopting FACS and MACS. Currently we have two main projects, as follow: (A) Discovery and development of anticancer therapeutics Development of cancer-cell selective proapoptotic anticancer biopharmaceuticals of TRAIL/Apo2L variant and human antibody by targeting death receptors. (B) Development of anti-viral therapeutics Engineeringof the nucleic acid hydrolyzing catalytic 3D8 scFv antibody to confer intracellular stability and virus specificity. Instruments In our lab, we have set up essential instruments for antibody and protein engineering, such as FACS (BD Calibur), MACS, Biacore2000, ELISA reader, etc. Those instruments are open to both in- and out-campus researchers. Publications 1. HW Lee, SH Lee, KJ Park, JS Kim, MH Kwon, and YS Kim (2006) Construction and characterization of a pseudo- immune human antibody library using yeast surface display. Biochem. Biophys. Res. Commun. 346(3):896-903. 2. YR Kim, JS Kim, SH Lee, WR Lee, JN Sohn, YC Chung, HK Shim, SC Lee, MH Kwon, and YS Kim (2006) Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity. J. of Biol. Chem. 281(22): 15287-15295. 3. YS Kim, R Bhandari, JR Cochran, J Kuriyan, and KD Wittrup (2006) Directed Evolution of the epidermal growth factor receptor extracellular domain for expression in yeast. Proteins: Structure, function, and Bioinformatics, 62(4):1026-1035. 4. MJ Jin, G Song, CV Carman, YS Kim, NS Astrof, M Shimaoka, KD Wittrup, and TA Springer (2006). "Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity." Proc. Natl. Acad. Sci. U S A. 103(15):5758-5763. Nano-Therapeutic Research Team Sang-Yo Byun, Ph.D. Phone: +82-31-219-2451, E-mail: sybyun@ajou.ac.kr, Homepage: www.ajou.ac.kr/~cellsep Present Professor Research Area and Interest - Manufacture functional nano-particles with supercritical fluid technology - Nano-particle generation, coating, impregenation, sterlization & cleaning - Application of bio-active materials to nano-particles Prospective effect of research By conferring functionality on nano-particles, this technology can be widely used for industrial application such as, drug manufacturing, cosmetics, and food. Publications 1. BY Won, HG Choi, KH Kim, SY Byun, HS Kim, HC Yoon “Bioelectrocatalytic signaling from immunosensors with back-filling immobilization of glucose oxidase on biorecognition surfaces” Biotechnology and Bioengineering 89, 815-821 (2005) 2. GW Lee, HC Yoon, SY Byun “Inhibitory effect of Eucommia ulmoides Oliver on adipogenic differentiation through proteome analysis”E nzyme Microb Technol 35: (6-7) 632. (2004) 3. HC Yoon, HS Yang and SY Byun “Ferritin immunosensing on microfabricated electrodes based on the integration of immunoprecipitation and electrochemical signaling reactions” Analytical Sciences 20 (9) 1249 (2004) 4. WJ Moon, BS Yoo, DI Kim and SY Byun, "Elicitation kinetics of taxane production in suspension culture of Taxus Baccata Pendula" Biotechnology Techniques, 12(1), pp.79-81, 98 5. SY Byun, “Re-Elicitation with Methyl Jasmonate in Eschscholtzia californica Cell Suspension Cultures” Journal of Microbiology and Biotechnology, The Korean Society for Applied Microbiology, 10(1), pp.107-110, (2000) NT(Nano Technology) NT(Nano Technology) Fig: Supercritical Nano-particle Processing Unit Nano-Therapeutic Research Team Sang-Wook Han, MD, Ph D Phone: +82-31-219-5195, E-mail: hansu@ajou.ac.kr, Homepage: hosp.ajoumc.or.kr/surgery 2004~Present Associate Professor in Department of Surgery, Ajou University 2001~2003 Visiting Fellow, Laboratory of Cell Regulation and Carcinogenesis, NCI/NIH 1999~2004 Assistant Professor in Department of Surgery, Ajou University 1996~1999 Instructor in Department of Surgery, Ajou University 1992~1996 Residency in Department of Surgery, Seoul National University Hospital 1991~1992 Rotating Internship in Seoul National University Hospital 1988~1991 Physician in ROK Army 1988 M.D.Seoul National University Research Overview Our main research area is designing and characterization of cancer-stem cell theory. Gastric cancer is the second most common cancer worldwide, with a frequency that varies greatly across different geographic locations. In Korea, gastric cancer is number one common cancer and top cause of death by malignancy. Despite some recent advances in chemotherapy, surgical therapy remains as the most effective modality in treating gastric cancer. But, inspite of effort in surgery, the overall 5-year survival rate of patients with resectable gastric cancer ranges from 10% to 30%. So other treatment tool is needed in the treatment of gastric cancer. Recently, cancer-stem cell theory appeared: cancer cells leads to the recruitment of bone marrow-derived stem cells. Research Overview The goal of our research is to develop stable cell therapy using mesenchymal stem cells. We designed in vitro invasion system which can explain recruitment of stem cells to tumor cells. We also developed tumorigenesis model using gastric cancer cells and stem cells. We set up cancer cell killing system by stem cell which transfected with suicidal genes. In the future, we will start human trial with stem cells. Publications 1. SU Han, YB Kim, HJ Joo, KB Hahm, WH Lee, YK Cho, DY Kim and MW Kim. Helicobacter pylori infection promotes gastric carcinogenesis in a mice model. J Gastroenterol and Hepatol 2002, 17:253-261. 2. SU Han, HT Kim, DH Seong, YS Kim, YS Park, YJ Bang, HK Yang, SJ Kim, Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer. Oncogene 2004, 23(7):1333-1341. 3. KT Nam, KB Hahm, SY Oh, M Yeo SU Han, BW Ahn, YB Kim, JS Kang, DD Jang, KH Yang, DY Kim. The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mice model. Clin Cancer Res 2004;10(23):8105-8113. 4. M Yeo, DK Kim, SU Han, JE Lee, YB Kim, YK Cho, JH Kim, SW Cho, KB Hahm. Novel action of gastric proton pump inhibitor on suppression of Helicobacter pylori-induced angiogenesis. Gut 2006, Jan, 55(1) 26-33. Nano-Therapeutic Research Team Pyung-Cheon Lee, Ph. D. Phone: +82-31-219-2461, E-mail: pclee@ajou.ac.k, Homepage: http://www.ajou.ac.kr/~molbiotech 2007~present Assistant Professor in Ajou University 2003~2007 Research Associate in University of Minnesota 2001~2003 Postdoc in University of Minnesota 1997~2001 Ph D in Korea Advanced Institute of Science and Technology My research is focusing on development of “Microbial Cell Factories” through interdisciplinary approach. Microbial Cell Factories are (1) “Customized cell factories” for new bioactive chemicals, (2) “Smart Biosystems” responding digitally to signals, and (3) “Protein Engineering Platform” for development of biocatalysts. These versatile Microbial Cell Factories can be successfully CREATED by rational and systematic strategies based on Synthetic Biology, Chemical Biology, Metabolic Engineering, and Omics. Research I ”Customized cell factories” for new bioactive chemicals consist of redesign, reconstruction, and system-level optimization steps along with protein engineering step. Research II ”Smart Biosystems” are composed of development of naturally evolved turn-on/off biosystems and optimization/fine-tune step. Research III ”Protein Engineering Platform” utilizes “core” or “scaffold” structures of existing biocatalysts to generate novel biocatalysts with altered activities and properties. Publications 1. Watts KT, Mijts BN, Lee PC, Manning AJ and Schmidt-Dannert C (2006) Discovery Of A Substrate Selectivity Switch In Tyrosine Ammonia Lyase, A New Member Of The Aromatic Amino Acid Lyase Family. Chemistry and Biology,13(12):1317-1326 2. Watts KT, Lee PC and Schmidt-Dannert C (2006) Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli. BMC Biotechnology, 6:22. 3. Mitjs BN, Lee PC and Schmidt-Dannert C (2005) Identification of a carotenoid oxygenase synthesizing novel acyclic carotenoids: combinatorial biosynthesis and directed evolution. Chemistry and Biology, 12: 453-460 4. Lee PC, Petri R, Mijts BN, Watts KT and Schmidt-Dannert C (2005) Directed evolution of Escherichia coli farnesyl diphosphate synthase (IspA) reveals novel structural determinants of chain length specificity. Metabolic Engineering, 7: 18-26 NT(Nano Technology) NT(Nano Technology) Research Overview Energy Technology ET G G G G G Energy System, Ajou University G G G G G G G G G G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G G G ET(Energy Technology) G G G G G G G G G ET(Energy Technology) G G G G