Annual Report 2012-2013 Canadian Council on Animal Care
Transcription
Annual Report 2012-2013 Canadian Council on Animal Care
Advancing the Ethical Use and Welfare of Animals in Canadian Science Annual Report 2012-2013 Canadian Council on Animal Care Contents CCAC Survey of Animal Use 2011................................................... 2 CCAC Guidelines on the Ethical Use of Animals in Science............4 Contributors to Guidelines Development..........................................5 Replacement, Reduction and Refinement Alternatives.................... 6 Fellowship Program..........................................................................7 Assessment and Certification of Canadian Institutions.....................8 CCAC Assessment Panels..............................................................11 Education and Training Opportunities.............................................12 Communications with Canada and Beyond....................................13 National and International Recognition...........................................14 Structure and Composition of CCAC Council.................................15 CCAC Board of Directors and Standing Committees .....................16 Secretariat Personnel.....................................................................17 Ensuring Good Animal Practice in Humane Science in Canada The Canadian Council on Animal Care (CCAC) is an autonomous and independent body, created in 1968 to oversee the ethical use of animals in Canadian science. It is a registered not-for-profit organization, and is governed by a Council of representatives from 22 national organizations. The CCAC is dedicated to the advancement of the ethical use and welfare of animals in science across Canada. To achieve these goals, it sets standards which incorporate expert opinion, scientific evidence, the values of Canadians and the ethical principles of replacement, reduction and refinement of animal use. Through an assessment and certification process, the CCAC verifies that institutions using animals for scientific purposes meet its standards. Additionally, the CCAC strives to disseminate information on its role and the use of animals in Canadian science to its constituents and the general public. The present report covers activities undertaken by the CCAC from April 1, 2012 to March 31, 2013. The report explores the various ways in which the CCAC works towards ensuring ethical animal use in Canadian science, how it functions as an organization and how it strives to carry out its mission into the future. In accordance with the CCAC’s commitment to transparency, a comprehensive summary of the latest statistics on the number of animals used in science is presented. Included is an outline on the integrative process of guidelines development as well as a detailed description of the CCAC’s assessment and certification program for Canadian institutions. This report also recounts the CCAC’s efforts at providing educational opportunities as well as its contributions to the public dialogue on the subject of animal use in science. By presenting this annual report, the CCAC endeavors to promote understanding, awareness and sensitivity to the ethical use of and care of animals in Canadian science. CCAC Survey of Animal Use 2011 The survey of animal use for scientific purposes in Canada is published annually using data provided by institutions participating in the CCAC Program. This data is important not only for accountability to the Canadian public, but also to better understand the nature of animal use in Canada. Analysis of the data provides valuable information that is used to develop better tools for animal care and use (and its oversight), and impacts guidelines and policy development. Number of Animals Used in 2011* by Institutions Participating in the CCAC Program Category of Animals 2 Number of Animals Fish 1,300,259 Mice 1,090,730 Rats 225,971 Birds 224,288 Cattle 216,588 Reptiles/Amphibians 90,010 Pigs 61,384 Animals, other 52,058 Rodents, other 26,532 Guinea pigs 25,095 Dogs 10,199 Cats 6,220 Nonhuman primates 4,355 TOTAL Animals Used in CCAC Certified Institutions in 2011 3,333,689 78.5% of animals used in science in 2011 were fish, mice and rats * Participants in the CCAC Program are required to submit their animal use data for a calendar year by March 31st of the following year. Collection, compilation and analysis of the data is normally completed by the end of the year; however, due to financial constraints, the results of the 2011 survey are the most recent data available. For more details, visit http://www.ccac.ca/en_/publications/audf 2011 DATA ACCORDING TO PURPOSE OF USE PUrposes of animal use in science PURPOSE OF ANIMAL USE Fundamental Research 1 2 3 4 5 EXAMPLES ● Assessing the influence of auditory stimulation on auditory development Studies to broaden knowledge of fish of essential physiological structures and functions and ● Studying migration patterns animal behaviours or habitats of wild animals FUNDAMENTAL RESEARCH MEDICAL OR CLINICAL STUDIES DEVELOPMENT OF PRODUCTS OR DEVICES REGULATORY TESTING EDUCATIONAL PURPOSES 2011 DATA ACCORDING TO CATEGORY OF INVASIVENESS OF PROTOCOL Medical or Clinical Studies Studies for medical purposes that relate to human or animal diseases and disorders Development of Products or Devices Studies to investigate potential therapies for humans and animals, before regulatory testing is carried out on the most promising therapies Regulatory Testing EXPERIMENTS THAT CAUSE LITTLE OR NO DISCOMFORT OR STRESS EXPERIMENTS WHICH CAUSE MINOR STRESS OR PAIN OF SHORT DURATION EXPERIMENTS WHICH CAUSE MODERATE TO SEVERE DISTRESS OR DISCOMFORT EXPERIMENTS WHICH CAUSE SEVERE PAIN NEAR, AT, OR ABOVE TOLERANCE THRESHOLD OF UNANESTHETIZED, CONSCIOUS ANIMALS Protocols are assigned a category of invasiveness based on a precautionary approach according to the potential level of pain and distress that animals may experience. The CCAC requires institutional ACCs to ensure that any potential pain and/or distress are minimized. Anesthetics and analgesics must be used; any exceptions require scientific justification and ACC approval. Animal-based regulatory testing required by governments to ensure the safety of pharmaceuticals, biologicals, chemicals, and medical devices Educational Purposes ● Studying rodents to better understand the genes involved in diabetes, cancer and arthritis ● Studying dogs to better understand and develop treatments for canine epilepsy ● Development of new dietary products for farm animals ● Studies undertaken to develop artificial organs ● Safety testing of vaccines on rodents and non-human primates ● Testing the efficacy of a new medication ● Training of veterinary students on disease prevention, diagnosis and treatment Teaching and training to communicate scientific concepts, and develop practical skills and expertise in ● Training of animal health technicians on vaccination, specific techniques X-rays and dental care 3 CCAC Guidelines on the Ethical Use of Animals in Science The delivery of the CCAC’s mandate is based on guidelines and policy statements that give clear direction to institutional animal care and use programs. Guidelines documents are developed and revised in response to the current and emerging needs of the research community, advances in laboratory animal care, and the needs of the Assessment and Certification Program. International Harmonization of Standards For each new guidelines document to be developed, a subcommittee of experts is established. These experts work together to produce a CCAC guidelines document that is based on sound scientific evidence and expert opinion, and has received extensive peer review. Strong peer involvement ensures guidelines are aligned with advances in science and animal care, nationally and internationally, and suited to the needs of Canadian institutions and investigators. Collaboration with international colleagues: 46 • Dr. Gilly Griffin, Guidelines and Three R’s Programs Director, chaired the international group that developed The ICLAS Working Group on Harmonization: International Guidance Concerning the Production, Care and Use of Genetically-Altered Animals. This document has been published in the journal Laboratory Animals. • Dr. Gilly Griffin, Guidelines and Three R’s Programs Director, and Dr. Michael Baar, Assessment and Certification Program Director, co-authored a chapter on the Canadian oversight system for the book Lab Animals: Regulations and Recommendations for Global Collaborative Research, providing a comparison of oversight systems throughout the world. Aligning Guidelines with Animal Welfare The CCAC invited a number of scientific societies, the Canadian Federation of Humane Societies, animal care committee (ACC) coordinators and senior administrators to recommend suitable candidates for several new subcommittees that are being established. Collectively, these new subcommittees will produce a series of guidelines documents to replace the array of topics covered in the CCAC’s Guide to the Care and Use of Experimental Animals, volume 1 (1993) and volume 2 (1984). These revisions are critical to align CCAC standards with current best practices in animal welfare and science. To streamline the presentation of guidelines, the new subcommittees will develop general principles for facility management, welfare assessment, husbandry, health and disease control, breeding colony/broodstock management, and experimental procedures. Other subcommittees working on species-specific guidelines (revisions of chapters of volume 2) will then be able to cross-reference these general principles and focus on requirements unique to their species of interest. Contributors to Guidelines Development Standards documents and related guidance RECENTLY PUBLISHED CCAC guidelines on: euthanasia of animals used in science (and relevant documents) UNDER DEVELOPMENT CCAC guidelines on: genetically engineered animals used in science CCAC guidelines on: the care and maintenance of marine mammals CCAC guidelines on: air quality of laboratory animal facilities CCAC guidelines on: the care and maintenance of nonhuman primates CCAC guidelines on: the care and maintenance of rats UNDER REVISION CCAC guidelines on: institutional animal user training Guide to the Care and Use of Experimental Animals, volume 1 and volume 2 Subcommittee on Biotechnology Dr. Bruce Murphy, Université de Montréal (Chair) Dr. Garth Fletcher, Memorial University of Newfoundland Mr. Darren Grandel, Ontario SPCA Dr. Gary Halbert, Canadian Food Inspection Agency Dr. Hélène Héon, Centre Hospitalier de l’Université de Montréal Dr. Eike-Henner Kluge, University of Victoria Dr. Lauryl Nutter, Toronto Centre for Phenogenomics Dr. Sui-Pok Yee, University of Connecticut Health Center Subcommittee on Nonhuman Primates Dr. Martin Paré, Queen’s University (Chair) Dr. Stefan Everling, University of Western Ontario Dr. Stéphane Goulet, Primus Bio-Ressources Dr. Jim Gourdon, McGill University Dr. Julio Martinez-Trujillo, McGill University Dr. Andrew Winterborn, Queen’s University Subcommittee on Mice Hélène Héon, Centre hospitalier de l’Université de Montréal Patricia Turner, University of Guelph Subcommittee on Rats Dr. Toni Bayans, University of Alberta (Chair) Dr. Patricia Turner, University of Guelph Dr. Lee Niel, University of Guelph Subcommittee on Air Quality in Animal Facilities Dr. Donald McKay, University of Alberta (Chair) Mr. Christopher Cosgrove, Cosgrove Facility Design Solutions Dr. Gilles Demers, CCAC Assessment Director Dr. Germain Rivard, MouseCare Dr. Ken Ugwa, Public Health Agency of Canada Subcommittee on Marine Mammals Dr. Pierre-Yves Daoust, University of Prince Edward Island Mr. John Ford, Fisheries and Oceans Canada Mr. Henrik Kreiberg, Fisheries and Oceans Canada Dr. Clément Lanthier, Calgary Zoo Dr. Kay Mehren, Veterinarian Emeritus, Toronto Zoo Ms. Tracy Stewart, Marineland of Canada Inc. Mr. Clint Wright, Vancouver Aquarium 5 Replacement, Reduction and Refinement Alternatives The Three Rs tenet (replacement, reduction and refinement) provides a set of guiding ethical principles that help to minimize adverse impacts to animals used in science and improve their welfare. It is widely accepted as the ethic of animal experimentation and is embedded in the conduct of animal-based science in Canada and throughout the world. The CCAC is internationally viewed as Canada’s Three Rs Centre, dedicated to the promotion of the Three Rs. Promotion of the Three Rs To promote the Three Rs internationally, the CCAC hosted the Eighth World Congress on Alternatives and Animal Use in the Life Sciences (WC8) in August 2011. The Proceedings of the Congress were published in May 2012 as a special issue of the journal ALTEX, and are available online. The CCAC’s commitment to promotion of the Three Rs is further emphasized through the Guidelines and Three Rs Programs Director’s participation on the PLoS Journal’s ethics advisory committee and on the editorial board for Laboratory Animals. Three Rs Microsite The CCAC’s Three Rs Microsite aims to support the practical implementation of the Three Rs by providing access to information applicable to the Canadian context. The Microsite was refreshed to harmonize with the CCAC website, and the Wildlife Research webpage was reviewed and updated by wildlife expert Dr. Marc Cattet, University of Saskatchewan. The Microsite is now updated weekly with “News & Publications,” and the scientific literature is reviewed regularly, with best practice information captured in a CCAC reference database. Promotion of the Microsite has resulted in many ACCs and international organizations (such as the US Interagency Coordinating Committee on the Validation of Alternative Methods and AltWeb) hosting links to the Microsite. 6 “ Three Rs documents Fellowship Program RECENTLY PUBLISHED Evaluating Environmental Enrichment is Essential (invited article in summer 2012 issue of Enrichment Record) The CCAC Fellowship program is an important part of CCAC’s work in understanding and addressing ethical issues relating to the use of animals in science. It provides an opportunity to bring together the novel research produced by CCAC fellows with the knowledge and experience of experts both within Canada and internationally. Dr. Marc Avey, the sixth research fellow, has been conducting research in two area of importance to the CCAC Guidelines and Three Rs Programs: pedagogical merit review of education protocols using animals; and systematic reviews and publication bias in animal-based research. Dr. Avey has completed the interview stage of his research on pedagogical merit review, and launched a national survey in June 2013. UNDER DEVELOPMENT Three Rs Review of Research Programs and Funding Grants (position paper) Strategies for addressing highly invasive animal use in Canada: How CCAC can drive reduction of animal use in Category of Invasiveness E (internal report) Best Practice Recommendations for Facilitating Sharing of Animals and Animal Tissues (report) “ The use of enriched environments offers the possibility of more robust animal models, and the ability to detect early onset of disease, and has the potential to improve both the quality of an animal’s life as well as the quality of scientific data. Read more in the summer 2012 issue of the Enrichment Record Ms. Shannon Duffus, the fifth research fellow, completed her fellowship on pain and analgesia in laboratory animals in December 2012. Ms. Duffus is writing up two papers based on her research: a web-based study that examined public attitudes toward the use of animals in research, conducted in collaboration with Dr. Daniel Weary, University of British Columbia; and an interview-based study that investigated analgesic practices in laboratory animals and obstacles to the refinement of painful protocols where analgesia is withheld. These papers will be submitted to peer-reviewed journals. The results of a study carried out by the third CCAC research fellow, Ms. Mara Long, was recently published: Long M. & Griffin G. (2012) Challenges and opportunities for the implementation of the Three Rs in Canadian vaccine quality control. Regulatory Toxicology and Pharmacology 63:418–425. 7 Assessment and Certification of Canadian Institutions The CCAC assesses the ethical use and care of animals for scientific purposes in Canada through a peer review process. Regular assessment visits are conducted by multidisciplinary teams of experts and community representatives and are based on CCAC guidelines, policy statements and associated documents. Institutions found to have satisfactory animal care and use programs are issued a CCAC Certificate of GAP – Good Animal Practice®. 8 The Certification Process Assessment Visits When conducting a visit, the panel assesses the structure and resources of the animal care and use program, the composition, functioning and effectiveness of the ACC, and the appropriateness of animal care and use practices, procedures and facilities. Types of Assessment Visits Orientation When an institution wishes to join the CCAC Program, an assessment director will visit the institution in order to explain the Program and briefly assess the institution’s strengths and weaknesses with respect to animal care and use. Regular These visits are conducted every three years in order for an institution to maintain its certification and are conducted by an assessment panel. Interim These visits are conducted by an assessment director when institutions have achieved two consecutive statuses of Compliance and have identified no significant changes or concerns. Special These visits are conducted by an assessment director between full assessments if conditions at an institution warrant it, or following a request by the institution. Reporting Following an assessment visit to an institution, the CCAC produces an assessment report which includes recommendations that must be satisfactorily answered in order for the institution to be certified. The institution must then submit an implementation report(s), thoroughly and clearly addressing the CCAC recommendations. 51 Assessment Visits Conducted 41 regular, 2 interim, 6 special, and 2 orientation visits were conducted Certification A CCAC Certificate of GAP – Good Animal Practice® is issued to institutions which have been found by the panel and by the CCAC Assessment and Certification Committee to have standards of experimental animal care and use which satisfy the CCAC’s guidelines and policy statements. 43 104 Implementation Reports Processed Institutional actions taken in response to CCAC recommendations must be detailed in an implementation report Assessment Reports Produced Assessment reports support institutions in achieving best practices in animal care and use, identify deficiencies, and include recommendations to help institutions improve their animal care and use program and meet CCAC standards 9 CCAC Certificate of GAP – Good Animal Practice® The CCAC Certificate of GAP – Good Animal Practice® is awarded to institutions with sound animal care and use programs that have earned a status of Compliance or Conditional Compliance. A one-year probationary certificate is awarded to institutions that have been assigned a status of Probation due to significant, unresolved deficiencies in their animal care and use program. Either certificate will be revoked should the institution be assigned a status of Non-Compliance for not addressing serious recommendations in assessment reports or if there is a major threat to animal health and well-being. 172 60 GAP Certificates Issued/Renewed 25 institutions were assigned a status of Compliance and 35 institutions were assigned a status of Conditional Compliance Total Number of GAP – Good Animal Practice® Certificate Holders in 2012-2013 110 academic institutions, 35 government organizations and 27 private organizations ACADEMIC INSTITUTIONS (research centres, colleges and universities) GOVERNMENT ORGANIZATIONS (research and testing centres) PRIVATE ORGANIZATIONS (conducting research, testing, or production of animals or biologics for scientific purposes) 10 Revised Definition of Animal Use Policy documents and related guidance The Assessment and Certification Sector and the Guidelines and Three Rs Sector (in conjunction with their respective committees and stakeholders) are currently working on a document that will clarify the CCAC’s definition of animal use. RECENTLY PUBLISHED CCAC policy statement on: recommendations made in CCAC assessment reports (and relevant documents) UNDER DEVELOPMENT CCAC policy statement on: scientific merit and ethical review of animal-based research CCAC interpretation bulletin on: post-approval monitoring CCAC interpretation bulletin on: human resources for animal care and use programs UNDER REVISION CCAC policy statement on: animal-based projects involving two or more institutions CCAC policy statement on: terms of reference for animal care committees CCAC policy statement on: assessment panels CCAC policy statement on: the assessment program of the CCAC Animal Care and Use Program Review Form (PRF) CCAC Assessment Panels CCAC assessment panels carry out visits to institutions participating in the CCAC programs based on CCAC guidelines, policy statements and associated documents. Each assessment panel is composed of a community representative, selected from a list of individuals nominated by the Canadian Federation of Humane Societies, at least one veterinarian, and a scientist, selected for their experience in animal experimentation and care relevant to the institution to be visited. A CCAC assessment director is present at every assessment visit as an ex officio member of the assessment panel. Veterinarians Dr. Anna Bolinder, University of Guelph Dr. Maryse Boulay, Consulting Veterinarian* Dr. Ronald Charbonneau, Consulting Veterinarian* Dr. Kathleen Delaney, McMaster University Dr. Jacinda Flood, University of Ottawa* Dr. Sylvie Fortier, Université de Montréal Dr. Susan H. Fussell, Consulting Veterinarian* Dr. Barb A. Hildebrand, Dalhousie University Dr. Ovidiu Jumanca, Institut de recherches cliniques de Montréal* Dr. Jennifer Keyte, Memorial University* Dr. Marcus Litman, University of Guelph* Dr. Stéphane Ménard, Université de Montréal* Dr. Badru Moloo, University Health Network Dr. Greg Muench, University of Calgary* Dr. Patrick N. Nation, Animal Pathology Services (APS) Ltd.* Dr. Valerie Smid, University of Manitoba Dr. Jonathan Spears, University of Prince Edward Island* Dr. Janet Sunohara-Neilson, University of Guelph* Dr. Ian D. Welch, University of Western Ontario Dr. Craig Wilkinson, University of Alberta Community Representatives Mr. Tim Battle, Edmonton, AB Mr. Roch Bédard, Ste-Adèle, QC Ms. Line Bélanger, Anagance, NB Mr. Hugh Coghill, Woodville, ON Mr. Martin Cole, Beaverton, ON Mr. Shawn Eccles, Surrey, BC Ms. Susan Edwards, Elora, ON Ms. Lise Gagnier, Le Gardeur, QC Mr. Michel Gélinas, Montreal, QC Mr. William Gelling, Ottawa, ON Mr. Brian Godfrey, Nanaimo, BC Mr. Darren Grandel, SPCA , ON Mr. Andrew Hebda, Halifax, NS Ms. Carolyn Hickey, St-John’s, NL Ms. Melissa Logan, SPCA, AB Mr. Clancy Martin, Sudbury, ON Mr. Don C. McKay, Puslinch, ON Ms. Janice Packard, New Liskeard, ON Mr. Issiaka Sanou, Les Serres du Dos Blanc, QC Ms. Evelina Smith, Sherbrooke, QC Ms. Sylvie Tremblay, SPCA Saguenay, QC* Mr. Robert Van Tongerloo, Manotick, ON Ms. Lindsay West, University of Regina, SK Ms. Christine E. Wooldridge, Shawinigan Lake, BC Scientists Dr. Mary-Jane Alcorn, College of Pharmacy and Nutrition* Ms. Linda Campbell, Vanier College* Ms. Susan Carter, University of Toronto Prof. Eileen Denovan-Wright, Dalhousie University* Dr. Peter Flanagan, University of Western Ontario* Ms. Karen Gourlay, McMaster University* Dr. Christopher Gray, University of New Brunswick Dr. Edwin Kroeger, University of Manitoba* Dr. David Lovejoy, University of Toronto* Dr. Pamela Martin, Environment Canada* Dr. Maria-G. Martinoli, Université du Québec à Trois-Rivières* Dr. Tom Moon, University of Ottawa* Dr. Lucy R. Osborne, University of Toronto* Dr. Dan Rurak, University of British Columbia* Mr. Martin Ryan, University of Waterloo* Dr. Albrecht I. Schulte-Hostedde, Laurentian University* Mr. Brad A. Steeves, University of Saskatchewan Dr. Don Stewart, Acadia University* Dr. Mark G. Torchia, University of Manitoba* * Identifies members who have served as chairperson on an assessment panel 11 Education and Training Opportunities The CCAC develops different educational and reference materials to support the training needs of ACC members, animal users and animal health professionals, and makes materials available through external links. These resources and events include the training syllabus, training modules and other educational materials, workshops, and web-based seminars. Training documents PUBLICATION PENDING CCAC training module on: beef cattle CCAC training module on: dairy cattle UNDER DEVELOPMENT CCAC training module on: poultry CCAC training module on: the care and use of fish in research, teaching and testing CCAC National Workshop 2012 CCAC National Workshops are two-day events, providing members of institutional ACCs with an opportunity to interact with peers and exchange information on challenges and best practices. The CCAC National Workshop 2012 took place on April 26–27, 2012 in Ottawa at the Delta Ottawa City Centre Hotel. Over 185 participants from 88 institutions/federal departments were in attendance at this workshop which included 2 plenaries, 14 parallel and 22 breakout sessions. There were also 22 speakers and 34 facilitators who presented and shared their expertise. The delivery of the National Workshop this year differed from previous workshops in that it I really hope that CCAC featured bilingual offerings of the plenary sessions will continue to offer this in a larger meeting space. The workshop attracted workshop on an annual a broad audience, including technicians, scientists, community and student representatives, researchers, basis in light of their current veterinarians, and administrators of institutional budget issues. I appreciate all animal care programs. “ Due to a shift in the CCAC’s funding model, the future of its national workshops is currently uncertain. The CCAC is exploring partnerships with other organizations in order to continue to offer this training opportunity. 12 of the effort/work that CCAC puts into this workshop and find it very valuable. CCAC National Workshop 2012 participant Communications with Canada and Beyond The CCAC strives to communicate effectively with the general public, the research community, and the individuals responsible for the care of animals used in science. The CCAC participates in media interviews to educate the public about the ethical use of animals in Canadian science. The CCAC also conducts research on public attitudes in Canada in order to stay abreast of public opinions and works to dispel misconceptions of animal-based science. Interviews ● Let’s Talk about Animal Research (Please?) OpenFile, April 12, 2012 ● Bloody Demonstration Protest Animal Testing CTV News, June 3, 2012 ● Regulating Animal Testing The Current, CBC Radio, June 8, 2012 ● UBC Defends Care of Research Animals: Releases 2010 Report Citing Deficiencies, Says Things Have Improved Vancouver Sun, August 31, 2012 ● Radio interview with Dr. Mark Torchia, Vice-chair of CCAC Council CJOB, March 18, 2013 @ 147,700+ people visited the CCAC Website in FY 2012-2013 Visitors by Country STOP UBC Animal Research (SUBCAR), an animal rights organization working to end research on animals at the University of British Columbia, has been very active since 2010. As a result, UBC has faced significant media attention regarding their animal care and use program, as well as disruptions to their day-to-day activities. In response, UBC has undertaken efforts to facilitate transparency regarding the ethical use of animals in science, and has consulted the CCAC to this end. Throughout this ongoing collaboration, regular communications have taken place between the CCAC and UBC to facilitate accurate and effective communication from each organization with respect to animal care and use in science. CANADA FRANCE UNITED KINGDOM UNITED STATES AUSTRALIA OTHER www.ccac.ca 13 National and International Recognition The CCAC’s work continues to be recognized by many groups and persons around the world, including: In 2012, Quebec, Newfoundland and Labrador joined Alberta, Manitoba, New Brunswick, Nova Scotia, Ontario, Prince Edward Island, and Saskatchewan in amending their legislation to address laboratory animals. In addition, many private and provincial government units have embraced the CCAC Program, recognizing the scientific and public relations benefits that a monitored animal care and use program brings. Newfoundland and Labrador On May 1, 2012, Newfoundland and Labrador amended the Animal Protection Standards Regulations, Reg 36/12 under the Animal Health and Protection Act (which makes reference to animals in which the custody, care or control of the animal for research, teaching or testing purposes) to require compliance with the standards published by the CCAC. Quebec In Québec, the ministère de l’Agriculture, des Pêcheries et de l’Alimentation du Québec is responsible for the Loi sur la protection sanitaire des animaux. The safety and welfare of animal provisions of this law specify that agricultural, teaching and scientific activities involving the use of animals are permitted provided that they are carried in accordance with generally accepted rules. In this respect, the ministry state the standards established by the CCAC. 14 ● the Organisation for Economic Co-operation and Development (OECD), which refers to CCAC guidance on appropriate endpoints for regulatory testing using animals ● the World Organisation for Animal Health (OIE), which used CCAC guidance to help develop chapter 7.8 on the Use of Animals in Research and Education in its Terrestrial Animal Health Code ● the International Council for Laboratory Animal Science (ICLAS) which uses CCAC guidance for the international harmonization of animal care and use guidance, as published in Science ● the US National Institutes of Health (NIH) and Food & Drug Administration (FDA), which recognize the CCAC Certificate of GAP – Good Animal Practice® Structure and Composition of CCAC Council COMPOSITION The CCAC comprises 22 permanent member organizations and up to three limited term member organizations, whose representatives include scientists, educators, and delegates from industry and the animal welfare movement. Each member organization has one seat on Council with the exception of the Association of Universities and Colleges in Canada (3), the Canadian Federation of Humane Societies (4) and the Canadian Faculties of Agricultures Sciences and Veterinary Medicine (2). MEMBER REPRESENTATION GRANTING AGENCIES HUMANE SOCIETIES ACADEMIC GROUPS ANIMAL CARE ASSOCIATIONS GOVERNMENT DEPARTMENTS AND AGENCIES CHARITY GROUPS RESEARCH-BASED PHARMACEUTICAL COMPANIES ETHICS SOCIETIES ROLE AND ORGANIZATION COUNCIL Composed of 28 representatives of 22 regular member organizations and responsible for establishing policy statements recommended by the five standing committees, electing the Vice-Chair, authorizing budget and ensuring the duties are performed Responsible for reviewing and evaluating assessment and implementation reports, and assigning CCAC statuses according to the CCAC certification process Responsible for identifying education and training needs and coordinating the development of training resources, and for coordinating external communications Responsible for identifying opportunities and coordinating the development of tools to promote and implement the Three Rs in Canadian science Responsible for identifying the need for CCAC guidelines and for coordinating their development Responsible for long-term planning, financial oversight and program management evaluation ASSESSMENT AND CERTIFICATION EDUCATION, TRAINING AND COMMUNICATIONS BOARD OF DIRECTORS THREE Rs GUIDELINES Chairs of the five standing committees and the Executive Committee EXECUTIVE COMMITTEE Chair Vice-Chair Past-Chair Executive Director PLANNING AND FINANCE Responsible for the property and business of the CCAC 15 CCAC Board of Directors and Standing Committees Board of Directors Dr. Martin Paré (Chair of Council) Canadian Council of Departments of Psychology Dr. Mark Torchia (Vice-Chair of Council) Association of Universities and Colleges of Canada Dr. Marina von Keyserlingk (Past Chair of Council) Canadian Faculties of Agriculture and Veterinary Medicine Dr. Eileen Denovan-Wright (Chair – Three Rs Committee) Association of Universities and Colleges of Canada Dr. Denna Benn (Chair – Planning and Finance Committee) Canadian Association for Laboratory Animal Medicine Dr. Anne Marie de Passillé (Chair – Education, Training and Communications Committee) Agriculture and Agri-Food Canada Dr. Doug Morck (Chair – Assessment and Certification Committee) Canadian Faculties of Agriculture and Veterinary Medicine Dr. Albrecht Schulte-Hostedde (Chair – Guidelines Committee) Canadian Society for Ecology and Evolution Dr. Norman Willis (Executive Director, Ex Officio, non-voting) Canadian Council on Animal Care Assessment and Certification Committee Dr. Doug Morck (Chair) Canadian Faculties of Agriculture and Veterinary Medicine Dr. Julie Chevrette Canada’s Research Based Pharmaceutical Companies Mr. Shawn Eccles Canadian Federation of Humane Societies Dr. Sylvie Marleau Association of Universities and Colleges of Canada Dr. Martha Navarro Health Canada Dr. René St-Arnaud Canadian Cancer Society Research Institute Dr. Éric Thorin Heart and Stroke Foundation of Canada Dr. Martin Paré (Ex Officio, voting) Canadian Council of Departments of Psychology Dr. Norman Willis (Ex Officio, non-voting) Canadian Council on Animal Care 16 Dr. Michael Baar (Ex Officio, non-voting) Canadian Council on Animal Care Ms. Marie Bédard (Ex Officio, non-voting) Canadian Council on Animal Care Dr. Gilles Demers (Ex Officio, non-voting) Canadian Council on Animal Care Dr. Denis Rainville (Ex Officio, non-voting) Canadian Council on Animal Care Ms. Jumoke Fasoyinu (Secretariat liaison person) Canadian Council on Animal Care Planning and Finance Committee Dr. Denna Benn (Chair) Canadian Association for Laboratory Animal Medicine Ms. Barbara Cartwright Canadian Federation of Humane Societies Dr. Marina von Keyserlingk Canadian Faculties of Agriculture and Veterinary Medicine Dr. Edwin Kroeger Association of Faculties of Medicine of Canada Dr. Mark Torchia Association of Universities and Colleges of Canada Dr. Martin Paré (Ex Officio, voting) Canadian Council of Departments of Psychology Dr. Norman Willis (Ex Officio, non-voting) Canadian Council on Animal Care Three Rs Committee Dr. Eileen Denovan-Wright (Chair) Association of Universities and Colleges of Canada Dr. Brian Hall Canadian Society of Zoologists Dr. Gordon Mitchell Canadian Food Inspection Agency Dr. Elizabeth Ormandy Canadian Bioethics Society Dr. Martin Paré (Ex Officio, voting) Canadian Council of Departments of Psychology Dr. Norman Willis (Ex Officio, non-voting) Canadian Council on Animal Care Dr. Gilly Griffin (Ex Officio, non-voting) Canadian Council on Animal Care Ms. Nicole Fenwick (Secretariat liaison person) Canadian Council on Animal Care Education, Training and Communications Committee Dr. Anne Marie de Passillé (Chair) Agriculture and Agri-FoodCanada Dr. Craig Bihun National Research Council of Canada Dr. Philip Byrne Fisheries and Oceans Canada Dr. James Gilchrist Association of Canadian Faculties of Dentistry Dr. Ira Hill Department of National Defence Ms. Teresa McKernan Canadian Association for Laboratory Animal Science Dr. Martin Paré (Ex Officio, voting) Canadian Council of Departments of Psychology Dr. Norman Willis (Ex Officio, non-voting) Canadian Council on Animal Care Ms. Pascale Belleau (Secretariat liaison person) Canadian Council on Animal Care Guidelines Committee Dr. Albrecht Schulte-Hostedde (Chair) Canadian Society for Ecology and Evolution Dr. Gregg Adams Natural Sciences and Engineering Research Council Mr. Darren Grandel Canadian Federation of Humane Societies Dr. James Sherry Environment Canada Dr. Patricia Turner Canadian Veterinary Medical Association Dr. Martin Paré (Ex Officio, voting) Canadian Council of Departments of Psychology Dr. Norman Willis (Ex Officio, non-voting) Canadian Council on Animal Care Dr. Gilly Griffin (Ex Officio, non-voting) Canadian Council on Animal Care Ms. Julie Dale (Secretariat liaison person) Canadian Council on Animal Care Secretariat Personnel Canadian Council on Animal Care •1510-130 Albert Street • Ottawa, ON, Canada K1P 5G4 • T: 613-238-4031 • F: 613-238-2837 • ccac@ccac.ca • www.ccac.ca Administration Sector Norman Willis Executive Director ext. 224 nwillis@ccac.ca Deborah Biehler Executive Assistant ext. 223 dbiehler@ccac.ca Michelle Lavoie Administrative Assistant ext. 264 mlavoie@ccac.ca Assessment and Certification Sector Michael Baar Assessment and Certification Program Director ext. 226 mbaar@ccac.ca Gilles Demers Assessment Director 450-467-4221 gdemers@ccac.ca Anne Thibaudeau Communications Director, Assessment and Certification ext. 232 athibaudeau@ccac.ca Marie Bédard Assessment Director ext. 229 mbedard@ccac.ca Jumoke Fasoyinu Certification Officer ext. 233 jfasoyinu@ccac.ca Denis Rainville Assessment Director ext. 261 drainville@ccac.ca Linda Rhéaume Administrative Assistant, Assessment and Certification ext. 227 lrheaume@ccac.ca Education, Training and Communications Sector Pascale Belleau Education, Training and Communications Coordinator ext. 234 pbelleau@ccac.ca Emily Verlinden Publications Coordinator ext. 231 everlinden@ccac.ca Felicetta Celenza Education, Training and Communications Assistant ext. 252 fcelenza@ccac.ca Charlotte Tellier Scientific Translator ctellier@ccac.ca Norman Lachance Webmaster ext. 230 nlachance@ccac.ca Guidelines and Three Rs Sector Gilly Griffin Guidelines and Three Rs Programs Director ext. 225 ggriffin@ccac.ca Julie Dale Director of Guidelines Development ext. 222 jdale@ccac.ca Nicole Fenwick Three Rs Program Coordinator nfenwick@ccac.ca Wendy Clarence Research Assistant ext. 228 wclarence@ccac.ca 17 For further inquiries regarding the CCAC please contact ccac@ccac.ca