Dean Li helps TMU lead in infotech apps for health
Transcription
Dean Li helps TMU lead in infotech apps for health
Vol. 4, No. 1, 2013 Special issue: Connecting with research Inside Dean Li helps TMU lead in infotech apps for health E Message from President Yen E Alumni magazine debuts E Student research takes on life-saving topics E Electronic records and hospital information systems in China E Which hormones influence polycystic ovarian syndrome? EEAhead of the pack: Recent bioinformatics publications E Research speeds HIV test results to save lives E Is the missing decade of aboriginal lifespan due to diet? E Applying new concepts of resilience to patient safety E ‘Mother of cancer research’ in Taiwan speaks E Malawi must protect people from catastrophic medical spending E Sage advice after a TMU year: prefer action over perfection E Mastering the menu: Eating well in 50 Chinese words or less E We care without distance E Table tennis helps TMU faculty put pressures aside E 53rd anniversary celebration and sports day <Editor’s note: In May, Dean YuChuan (Jack) Li of the College of Medical Sciences and Technology took time to walk TMU Outwards through the university’s history from the perspective of computerization. Dean Li was recently appointed as Editor-in-Chief of the SCI journal Computer Methods and Programs in Biomedicine (more often called by its acronym, CMPB). This marks the first time the journal has been led from Asia in its 40-year history. CMPB is in the top 14% of its peer journals, and it receives more than 700 papers each year, of which only 20% can be published. The journal remains based in Europe, but during the five years that Dean Li was Asia-Pacific Associate Editor, its Asian contributions increased 100%. Dean Li has been awarded as Academician by American College of Medical Informatics since 2010. He practices dermatology as well as leading TMU’s internationally noted Biomedical Informatics graduate studies program. Here are his reflections on where informatics research will lead in TMU’s future.> In the beginning of 1995, it became time to invest in a fiber optic network system to connect the campus and the hospital. We went with an IBM system and we established the first website for medical university in Taiwan on the August of 1995 I assumed the position of IT director of both the university and the hospitals for the next 12 years. (Continued on page 4) Message from President Yen TMU student research takes on life-saving topics Greetings to all of the readers of TMU’s English magazine. This special issue on research helps to tell TMU’s most important story: its mission to focus on translating research to useful clinical practice. For example, we have established a biobank to help our scientists and collaborators prove their concepts. We also are completing work on a “value added” database using National Health Insurance information. This vast repository of information can be a source of answers about treatments, risk factors and medication use. “Big data” is also the resource behind our brand-new biostatistics center, which makes biomedical information translatable from bench to bedside. We are also working hard to optimize a joint Institutional Review Board and clinical trial procedures to make it easier for clinicians to perform research. They can conduct trials to test hypotheses as well as to develop new treatments and medical devices. We are expanding our research and clinical faculty to find useful and applicable knowledge. Serendipitously, we are moving on to help our community and our country in partnership with businesses. These Electronic records and hospital information systems in China James Andrew Worley, Biomedical Informatics, United States My master’s thesis partnerships allow faster progress, and also faster transfer of these good ideas into practice. Our challenge is often a matter of space, but we have bold new plans to expand the TMU campus as well. Stay tuned, because TMU will continue to get bigger and better. n “Clinical and (Text by TMU Office of Public Affairs; translation by Jin Lin) initial issue of TMU Alumni in January, with the next issue due in July. This publication allows alumni to keep in touch with TMU and to stay informed about what their old friends are doing. This issue features a special interview with Taitung’s Daren Township health center director, Dr. Chao-Bing Hsu. But the biggest news is the start of a new alumni association and each department’s outreach to our alumni. This issue discusses the mission of this alumni association, as well as our alumni’s reflections upon their schools. The dean and chair of each department and every TMU hospital introduce the many 2 Which hormones influence polycystic ovarian syndrome? Ala’a Kutkut, Medical School, Jordan TMU alumni magazine debuts The Office of Public Affairs published the research will focus on China’s implementation of electronic hospital information systems (HIS) and electronic medical records (EMRs). This research will document the progress China has made in incorporating effective HIS, including EMRs, within its national hospitals. I would like to determine at what standardized levels China has these health IT platforms in current operation. If necessary, this research may involve a standardization assessment system to uniformly sort and analyze this data. I will review distinctive regional and national milestones in relation to current trends in biomedical informatics, as these important factors are relevant to this topic. Individual patient records have been handled in various ways by the administrators tasked with keeping these records accessible and up-todate. I will explore these records-handling procedures in detail because it is not logically appropriate to keep such lab records and body scans in printed-out media. I will use a theoretical model to plot and rate hospital units accordingly. n new research centers and discuss biomedical industry breakthroughs and the new era of medical education, such as the six-year clinical pharmacy degree that was recently approved. The magazine also discusses TMU’s rise in international rankings to Taiwan’s number two in medical and science education (following only National Taiwan University). In addition, there are some romantic stories about our students who met their mates in various TMU departments and student clubs. The editors invite all alumni to submit writing for publication. In this way everyone can help the garden of TMU’s influence bear new blossoms. n Biochemical Presentations of Hyperandrogenism” discusses which of the four abnormally elevated androgen groups (total testosterone [TT], androstenedione [A], free androgen index [FAI], or dehydroepiandrosterone [DHEAS]) present with an unfavorable metabolic and hormonal profile that is more insulin-resistant and poses additional cardiovascular risk. My results show that subjects with excess FAI are obese and face the highest metabolic syndrome risk, adipocytokine alterations, insulin resistance and cardiovascular risk. The excess TT group presents with higher gonadotropin dysfunction and marginal insulin resistance risk. The excess A group has the highest AMH, which may counterbalance obesity; this group and the excess DHEAS group have a favorable association with insulin resistance. Hyperandrogenism is a predominant criterion in polycystic ovary syndrome (PCOS) according to Androgen Excess and PCOS (AE-PCOS) Society diagnostic criteria. While differences between PCOS phenotypes have been reported, no research until this study has examined independent abnormally elevated androgen measures to observe differences in metabolic endocrine features and insulin resistance. Thus I conducted a retrospective study in 121 Taiwanese women with hyperandrogenism and 142 women without hyperandrogenism, with medical records reviewed from June 1, 2009, through July 21, 2012 classified women into four groups according to abnormally elevated androgen measures each above its cut-off value, and the groups were compared with each other and with controls. It is important to understand the roles of different androgens contributing to hyperandrogenism and to offer appropriate treatment to those facing the greatest health risks; this research gives an evidence base to those decisions. n 3 Ahead of the pack Recent TMU bioinformatics publications 1. M-health (use of mobile phone technologies for health applications) Wen-Shan Jian, Min-Huei Hsu, Hosea Sukati et al. (2012). LabPush: A Pilot Study of Providing Remote Clinics with Laboratory Results via Short Message Service (SMS) in Swaziland, Africa. PLoS One (7):e44462 Syed-Abdul S, Scholl J, Chen CC et al. (2012).Telemedicine Utilization to Support the Management of Burns Treatment Involving Patient Pathways in Both Developed and Developing Countries: A Case Study. Journal of Burn Care Research 2012 Jul;33(4):e207-12 2. EMR/PHR (electronic medical record systems and portable personal health records) Wen-Shan Jian, Shabbir Syed-Abdul, Sanjay P Sood et al. (2012). Factors influencing consumer adoption of USB-based personal health records in Taiwan. BMC Health Services Research (12):277 Li YC, Detmer DE, Shabbir SA et al. (2011) A global travelers’ electronic health record template standard for personal health records. JAMIA (Journal of the American Medical Informatics Association). doi:10.1136/ amiajnl-2011-000323 3. Social network applications for health Shabbir SA, Lin CW, Scholl J et al. (2011) Facebook use leads to healthcare reform in Taiwan. Lancet, June 18. 377(9783):2083-4 Special issue: Connecting with research (Continued from page 1) In 1997, with the opening of the new Wan Fang Hospital, we adopted a new health information system that covered both our TMU hospital and Wan Fang. However, what happened over time was that the hospitals evolved into separate systems. In a way they were competing with each other, which is not all bad. Twelve years later, I decided to make a job change from managing the hospitals’ IT operations, which had grown essentially from a staff of two people to almost one hundred between the campus and the hospitals. It had been a position of incredible pressure – even banks’ IT isn’t as critical as hospitals’ data operations. After all, banks close every night but we operate 24 hours, constantly collecting and managing patient data. And with banks it’s only money – with hospitals, lives are at stake! So in 2006, I accepted an offer from National Yang Ming University to chair their newly reformed Department of Biomedical Informatics. Here I saw the academic side of biomedical informatics in a department with sixty graduate students.Yang Ming is a national university, so it has both space and funding, things that TMU has to work very hard for on its own. So I had three years to focus on pure research. But in 2009, Wen-Ta Chiu, then TMU’s president, again asked me to return to TMU. He knew how to convince me; he said “We need you more than they do.” He called every now and then to ask me to return to TMU. I took the job because he has been a friend, a mentor and a father-like influence for me. I gave up the life-time benefits of being a government employee and returned to start a project to reintegrate the three hospital information systems. Our teaching hospitals work on a military-style model, with a strict hierarchy – the Superintendent has final say over absolutely everything. The university is more democratic, so it took several years to integrate these different systems. In fact, it was only several months ago that we finally announced that we have integrated the three hospitals’ information systems. Prof. Ray-Jade Chen of the Management and Development Office, who coordinates the three-hospital system, manages this now. (Continued on page 12) 4. Medical decision support for physicians Hsieh CH, Lu RH, Lee NH et al. (2011) Novel solutions for an old disease: diagnosis of acute appendicitis with random forest, support vector machines, and artificial neural networks. Surgery 149(1):87-93 Chang YJ,Yeh ML, Li YC et al. (2011) Predicting Hospital-Acquired Infections by Scoring System with Simple Parameters. PLoS One 6(8): e23137. doi:10.1371/journal.pone.0023137 n 4 Minister of Health Wen-Ta Chiu (fifth from left) joined a press conference to note an M-Health research milestone at TMU. Research speeds HIV test results to save lives: African study of M-health app cuts test times by 75% The respected biomedical journal PLOS One has published TMU’s LabPush study about the effectiveness of providing remote clinics in Swaziland with laboratory results via SMS (short message service). To mark this occasion, TMU held an inspiring multimedia press conference to discuss the background of this historic study. A TMU student from Swaziland, Sharoon Hlatshwayo, performed music and dozens of reporters gathered to hear Minister of Health Wen-Ta Chiu speak in praise of the project. “Although other projects use SMS for health applications at remote African clinics, no studies have been published that measure their effectiveness.” Dean Jack Li designed a service to return test results by SMS, hoping to reduce the turnaround time from a month to a few days. This has the potential to lead to better service, fewer patients lost to treatment and more appropriate dosing. The TMU team thus set out to both develop such a service and measure its effectiveness to support evidence-based development of the Swazi health care system. The study shows that SMS delivery of lab reports can reduce turnaround times by up to 75% for remote clinics. The TMU team learned The problem addressed additional lessons relevant by the project was that to other M-health projects lab results for HIV tests in Africa. For example, the often took a month to be process of getting hostreturned to Swazi patients government approval was because delivery motorbikes expected to be short, but travel infrequently between it took 18 months due to clinics and central labs. Bad inter-agency delays. Paying roads and limited public staff to log each test time transport meant that Swazis was expected to increase who travelled hours to be reliability, but in fact this was tested often returned via the a recurring issue because same difficult routes -- only of noncompliance and to find that their test results Swazi student Sharoon Hlatshwayo inaccurate recording by lab have not arrived. Delays in joined Dean Jack Li at the LabPush and clinic staff. test results can also lead to event to sing for television reporters. suboptimal medication dosing, The study and the since by the time a test result lessons learned can help returns, the patient’s T-cell count is already a future efforts to use this powerful and month out of date and requires a new test. widespread technology. The Swazi study This makes the overall clinical situation for also provides evidence that Taiwan is processing blood tests difficult for patients. spreading its technologies internationally It was this situation that troubled the Taiwan Medical Mission operated by TMU. As the university was already using mobile phones for health via the SANA project of the Massachusetts Institute of Technology, College of Medical Sciences and Technology to enhance health services in developing countries. The full paper can be read at: http://www.plosone.org/article/ info%3Adoi%2F10.1371%2Fjournal. pone.0044462 n 5 Is the missing decade of aboriginal lifespan due to diet? Special issue: Connecting with research Trista Di Genova, Public Health and Nutrition, United States Many great advances in medicine over the past 50 years have translated to a 10-year plus increase in average life expectancy in Taiwan. However, scholars point out the continued existence of a persistent gap in life expectancy – Aborigines lives on average 10 years less than the general population. A great part of indigenous deaths can be attributed to preventable causes related to ‘lifestyle choices’ such as traffic accidents, cirrhosis, or cancers related to betel chewing, smoking and alcohol. Aboriginal children eating junk food: photos by Trista di Genova how their diet is changing over time by conducting a cross-generational 24-hour food recall survey. ‘Mother of cancer research’ in Taiwan speaks This remote, picturesque mountain area (pop. 4500, primarily Atayal tribal people) could be considered a fruit basket of Taiwan. Residents here usually grow their own fruits and vegetables, and this industry has in recent years become a bigger piece of the local economy so that some earn a good living selling their small-scale farming produce. Editor’s note: Dr. Jacqueline Whang-Peng has been nicknamed “the Mother of Cancer Research in Taiwan” due to her pioneering efforts in cancer research. An Academic Sinica scholar, she currently works at Wan Fang Medical Center and Taipei Medical University Hospital’s International Cancer Institute. She spent thirty years as the first woman on the medical staff at the United States National Institutes of Health (1960 to 1990) and continues to maintain close ties with her US colleagues. Professor Whang-Peng was both the first female surgeon in Taiwan and also the first non-US-born female recipient of the Arthur S. Flemming Award. We had a chance to talk with her about the future of cancer treatment at her Wan Fang office. My fieldwork feels exciting for its relevance because I study what the Atayal grow for themselves to eat – quite literally measuring what’s in their gardens. They also are teaching me how they work with the land, their views toward nature and the environment, and about Atayal culture and Yet some Aboriginal populations experience less incidence of certain diseases than the general population. Such is the case of the Atayal in Hsinchu County, Farmers in Chingchuan, a mostly where I’m conducting aboriginal mountain village. nutrition fieldwork. I’m language. investigating the dietary habits of the Atayal because they retain many aspects of an And if you think Taiwanese people are age-old traditional diet. Compared to the friendly, you should come and meet these modern diet that is high in sugar, salt, fried people – they’re ten times friendlier! This foods and chemicals, this diet eaten in the is one big reason why I’ve moved into the mountains can be considered a model as it mountains. I’m going to love this hands-on is still full of fresh fruits, vegetables and lean field experience, so thank you TMU for meats hunted from the forest. everything these past two years, for the So I am looking into what aspects of the traditional diet the Atayal are retaining and Based on an interview with Heather Chen, Taiwan Tech Trek intern What is happening in cancer research at Taipei Medical University? At TMU, we do have very good research on breast cancer. We have found that breast cancer also has a high amount of nicotine receptors. That is what we want to target on for breast cancer. Do you have any comment on the government cancer prevention policies? Do you think they’re effective? Do you recommend any changes? scholarship and good times. Really, I couldn’t have chosen a better place to study. n Right now we have problems for prostate cancer. That is the one important direction for cancer research. Screening is not helpful because prostate cancer only shows up when it is at later stages. We have so many things for women in breast, colorectal, and cervical cancer. But nothing for cancer for men. We need to emphasize on prostate research. We need to use the digital PSA (plastic specific antigen) to do very early detection, especially for aggressive forms of prostate cancer. Applying new concepts of resilience to patient safety Eliana Rubashkyn, Health Care Administration, Colombia A decade ago, medical errors and adverse 6 events produced in hospitals were among the top 10 leading causes of death in the U.S., even above breast cancer and AIDS. Recently TMU researchers Prof. Sheuwen Chuang and Eliana Rubashkyn have been working to apply the concepts of resilience engineering and “safety II” in a model intensive care unit in Taiwan. Resilience engineering, according to Cook and Woods, is a way that people at all levels of an organization can try to anticipate paths that might lead to failure, as well as to create and sustain strategies resistant to failure, and adjust tasks and activities to maintain safety margins despite workplace pressures to do more and to do it faster (“Nine steps (Continued on page 9) One of my priorities is that we do more research on colorectal cancer. There are people who say that it has something to do with your diet. I remember an English researcher went to Uganda and he noticed that the foreigners had the colorectal cancer whereas the native people did not. He went to their home to see what they eat. Native people eat vegetable roots because they are poor. So, they have a lot of fiber rich foods. The Taiwanese now have colorectal cancer. Our economy is getting better and people are getting richer. So a lot of people don’t eat as many vegetables as before. (Continued on page 15) Photo at US NIH, 1960s. 7 Special issue: Connecting with research Malawi must protect people from catastrophic medical spending Dominic Moyo, Malawi (This article appeared in Malawi’s major newspaper, the Nyasa Times) Recent news reports of drug shortages in public hospitals are unfortunately not news. Far from being an isolated lapse, such deadly shortfalls are a perennial problem. Insufficient services, facilities, medical supplies and human resources also have led to a loss of trust in Malawi’s health system. When I worked in the public hospitals, many patients came to these facilities as their last resort, in desperation because they could not afford care elsewhere and had to settle for what little care they could get from public hospitals.Yet the technically free care these facilities offer poses different economic challenges for the poor that leave many unable to complete treatment or procure necessary medications. In reality, this free care is difficult to access and low in quality. Less than 10% of the national budget goes to health, in contrast to the WHO-sponsored Abuja Declaration signed in 2001 by many nations committing to spend at least 15% on health. Malawi’s health budget allows only about US$ 25 per person per year for health services – just over half of the US$ 44 specified as the lowest possible level to provide essential services by the Taskforce on Innovative International Financing. Thus current financing can only provide half of what might in the best case (with no waste and good planning) be sufficient care. Drug shortages at hospitals 8 Filling this financial gap to purchase health care becomes a major challenge when people have to spend money from their pockets. This is especially worse for people in rural areas, where medical services are almost nonexistent.Very poor people must first pay for transport to a health facility that Sage advice after a TMU year: prefer action over perfection Bamodu Oluwaseun, Nigeria has erratic supplies of medications and other medical necessities. So then they must find drugs in pharmacies, and pay more. Starting in 2001, global health initiatives poured money into Malawi for more than half a decade, with the Global Fund, World Bank and PEPFAR among others initiating vertical programs to reach vulnerable people and reduce out-of-pocket health costs. Then the economic crisis saw budget cuts and withdrawal by major bilateral donors. Now a single illness or accident can shift poor families into crisis as health costs continue to increase. In 2000 WHO said health systems should protect people from catastrophic health expenditures, defined as when households spend more than 40% of disposable income on health after subtracting subsistence costs. Given the current economic turmoil, Malawi is failing utterly on this count: subsistence costs are increasing while incomes are not. Budget allocations to public hospitals have not increased, leaving most to operate in debt and lacking basic necessities. Many people thus spend their disposable income on medications and other medical expenses. This out-of-pocket expenditure on health is regressive (affecting the poor more than the rich) and prevents people from accessing desperately needed medical services, since only those who can pay receive treatment. Prepayment insurance Prepayment of health services is the best form of health financing; many countries have implemented this form of revenue collection and have excellent health systems. Yet only private institutions like the Medical Aid Society of Malawi provide this, and their premium costs are prohibitive to an average rural resident. (Continued on page 14) Nothing I had done in the past could have adequately prepared me for a stress-less first year in the Graduate Institute of Clinical Medicine. So here are some wisdom nuggets from a green-horn. A lot of reading and learning is demanded, but success requires a focused learning precisely directed toward an eventual publication/dissertation. By my second semester, I learned that signing up for non-required (elective) courses outside of my area of interest was unnecessary. Like many ill-advised pursuers after excellence in graduate school, I went too far with relevant project title search, read so much and broadly about my intended research interest that I almost never started any real benchwork. My advisors were beginning to lose patience with their ‘eternal’ student, who seem bitten by the ‘want to learn everything, but do nothing’ bug of graduate school. What was the goal? Making a contribution to human knowledge. A graduate degree is not a game of acquisition but of contribution. It is not how much you know, but how focused you are. The price I paid for this enlightenment was a wasted first semester. Not perfect, but it works! Being a perfectionist, I kept looking for the green light of approval from tutors and advisors that I had a perfect research outline. This kept me from starting on laboratory work until that perfectionist in me died. To those trailing after I say: however it looks, start the work anyway. Success never embraces the procrastinator. Like my advisor always told me: ‘Don’t think too much, just do it!’ Begin your bench-work right away. Way into my second semester I realized that the project topic matters less than getting the degree. It does not matter what I get my degree in; it is the training that matters, not the topic. Once a man has been taught to shoot, he can keep shooting until he hits the bull’s eye. To make a big impact in graduate school is like hitting a bull’s eye at first shot. The degree is only a starting point, not your final undertaking in the world of science. Madman chasing knowledge Sanity is a relative perception; we classify those different from and unlike us as mad. But really, are they? In this pursuit, let not your short-sightedness ruin the vision of a bright tomorrow. Do not allow what you know to hinder the reception, processing and application of the knowledge of what is not known. An open mind is a teachable mind, a teachable mind is a brilliant mind, and a brilliant mind is a winning mind. Welcome to the world of professional thinkers. n Resilience and patient safety (Continued from page 6) to move forward from error”; Cogn Technol Work 2002; 2: 137-144). is impossible to encapsulate a linear solution for a dynamic threat. Why is patient safety still not improving much? In part because, as Leape and Berwick concluded, “The more complex any system is, the more chances it has to fail.” Safety traditionally has been seen as a condition where the number of adverse outcomes is as low as possible and total safety means that nothing was done wrong. This perspective on safety intends to look at the negative and tries to eliminate it. However the nature of an adverse event is dynamic; it Hollnagel and Chuang argue instead that health systems are complex and adaptive in the nature of a socio-technical system. Compliance to standards is not always possible due to human behavior factors, as humans adapt their behavior according with the current situation and environment. Understanding and working with complexity requires a shift in paradigm from linear thinking to dynamic, holistic and systemic thinking. n 9 Mastering the menu: Eating well in 50 Chinese words or less By Dana Jensen, Health Care Administration, United States Ordering from a Chinese menu can be a huge challenge -- even for people who are proficient in Chinese. Menu items may have confusing names that don’t tell you much about the ingredients or preparation, and many dishes might have very similar names. Luckily, by knowing just a handful of words, you can get a reasonable (if not exact) idea of what you’re ordering. By leaving some details of the order to chance, you get a great chance to find new foods you might never try otherwise, while still staying within your comfort zone. The basics When we’re trying to pick a restaurant for dinner, my Taiwanese roommates will often ask me what kind of food I want: street food, noodles, rice, or soup? While it may seem strange at first, the majority of Taiwanese/Chinese foods fall into one of those categories. If you select a restaurant at random and look at their menu, you’ll see several words repeated over and over. Just pick your favorite and you’ll at least have a general idea of what you’re getting. Fried rice is the way to go when you want a classic, tasty, simple lunch.There are several restaurants on “food street” alone that serve it, with dozens of flavors between them.The food translation list should cover all the basics, so be sure to try something you haven’t had before! Noodles 麵 Miàn Rice 飯 Fàn Soup 湯 Tāng Bread 包 Pancakes 餅 Bāo Bing Protein The names of most meats are much easier to learn in Chinese than in English. Instead of beef/pork/mutton, the Chinese names directly translate as “cow meat/pig meat/ sheep meat.” If you see the character for an animal followed by the word for “meat,” then you know what type of meat you’ll be getting. If it’s just the word “meat” without a specific animal listed, it’s going to be pork. Unfortunately sea animals are named differently, but they’re listed below. Soy-based foods will include the character listed in a number of different forms. Daily is a great Japanese-influenced restaurant just south of school, with wonderful chicken and pork cutlets, omelette rice and other favorites! The menu is partly in English. Sweet Lemon, a Southeast Asian-influenced restaurant in the main “food street” by the hospital has dozens of popular rice and noodle dishes, as well as huge drinks. Their menu is bilingual, so you can use it to practice using the food translation list! Vegetables Drinks The all-purpose word for vegetables is actually the same word that’s used for “dishes” or “food,” so this can be a little tricky. However, when you see this character as part of a longer item, it pretty much guarantees there will be a leafy green vegetable inside. Other important additions are listed. Often the menus are even larger at drink shops than at restaurants! Luckily, they’re usually fairly simple to understand if you know what to look for. Combining the words below yields dozens of possible drinks. Remember that black tea translates as “red tea” in Chinese. Also, if you want your milk tea made with real milk instead of powdered milk or non-dairy creamer, make sure it says “fresh milk.” Often drink shops are able to substitute fresh milk at a small additional cost. Meat 肉 Cow 牛 Niú Pig 豬 Zhū Sheep 羊Yáng Chicken 雞 Duck 鴨 Yā Fish 魚 Yú Leafy greens 菜 Cài 瓜 Guā Ròu Jī Crab 蟹 Xiè Gourd / pumpkin Shrimp 蝦 Xiā Onion 洋蔥 Corn 玉米 Yángcōng Yùmǐ Oyster 牡蠣 Mǔlì Clam 蛤 Há Tomato 西紅柿 西蘭花 Xī lánhuā 竹 Soy 豆 Dòu Broccoli Egg 蛋 Dàn Bamboo Wonton. Lots of places around campus serve wontons/餛飩/húntún, so try a bunch and find your favorite! I like these “giant” pork wontons from a shop at the north end of Wuxing Market. One of the stalls in TMU’s own cafeteria serves a fantastic bowl of wonton noodle soup. Chuang’s is a relaxing shop close to school where you can get delicious drinks, very nice pastas, and several tasty risottos. There is no English menu, so be sure to bring your translation list. It’s well worth the extra work! Xīhóngshì Fresh 鮮 Xiān Zhú Tea 茶 Chá 紅 Hóng Eggplant 茄子 Qiézi Red Cucumber 黃瓜 Huángguā Green 綠 Sauces Especially when you’re ordering pasta, it helps to know what sauce you’re going to get. There are far too many sauces to list, but I’ve given several common ones. Nǎiyóu Cream 奶油 Curry 咖哩 Ketchup (tomato) 番茄醬 Fānqié jiàng Garlic 大蒜 Dàsuàn Wine 酒 Jiǔ Gālí Please note: Many words I’ve listed appear in their “short form” as they would be used on menus, not as they would appear alone. n 10 Just across from the TMU Hospital emergency room, you’ll find the local “food street.” Pretty much every shop in this alley sells either food or drinks, all at very reasonable prices.You can get a meal for as little as 30NT, and prices don’t get much higher than 150NT in these restaurants. Oolong 烏龍 Milk 奶 Tapioca pearls 珍珠 Winter melon 冬瓜 Juice 汁 Apple 蘋果 Orange 橙 Guava 番石榴 Lemon 檸檬 Watermelon 西瓜 Lǜ Wū lóng Nǎi Zhēnzhū Dōngguā Zhī Píngguǒ Chéng Fān shíliú Níngméng Xīguā Mángguǒ Mango 芒果 Strawberry 草莓 Cǎoméi Grape 葡萄 Pútáo Coffee 咖啡 Kāfēi 11 M-health apps provide decision support for patients, clinicians (Continued from page 4) Academic leadership logic is different, this has been proven. Since 2011 I have been the dean of this college, a position which allows me more time for research and clinical duties. In the first year of studying in English, students cannot dream in their new language – but after that, their logic changes. For one thing, in English the business being communicated is up front, not the modifiers and qualifiers and politeness. In Chinese, those modifiers are equal in importance to the subject itself. “Technology drives these changes, we don’t invent them. All across the planet, even the poorest areas have these affordable, sophisticated tools. It’s a shame if we don’t use them!” And in fact from the first day I came back to TMU in the 1990s, I thought it was an underrated area of the university. I launched this young department with a public relations event – the first direct real-time broadcast of surgery from the operating theater to a conference room where reporters could ask questions of the surgeon. I felt that we should let people know what we’re doing; we do want to share these ideas with the public. So you need simple words to explain complex situations. Student research ideas We do not force students to research a particular topic suggested by faculty. Instead we give them six months to come up with their own ideas, to explore different areas and see where they would like to work on research. We ask them to have three to five research ideas to discuss, and we give them feedback about the practical considerations, the value and the chances of success of each research idea. This has broadened our department; over ten years our research profile has been one of variety and diversity because over 50% of students came up with their own ideas and pursued them. And our lab has always been in English – even before we had foreign students in the department. This was very unpopular at the time; in fact they said it couldn’t be done. But I did it because when I heard our students give conference presentations, it hurt my ears! English for thinking 12 And we can’t switch back, because we want our students to be comfortable and competent in international conference situations. Beyond that, students think differently in English and in Chinese. The And this is deadly in science writing. Don’t hide your subject! This reflects the different attitudes of Taiwanese and American cultures. Phones for health Now our research has grown from that early gee-whiz PR event to help give feedback to clinicians. This is one way that marrying IT with medicine can have a big impact on medical practice, and it is the roots of M-health, or technologies that use mobile phone systems to assist health professionals and patients. For one thing, M-health is a very practical way of providing IT systems to underresourced areas. For example, the SANA project that we are partnering with MIT (Massachusetts Institute of Technology this time, not Made In Taiwan) is working in Pakistan to lower the very high infant mortality rate by tracking all married women so they can be informed about and urged to access health services. M-health is more concerned with applications than research. HIT (health information technologies) like this can amplify our efforts with proper deployment. But the more original research we’re doing is in the area of medical decision-making. With optimal use of computers and information, we can use electronic records to help clinicians as well as to handle automatic follow-up with patients about appointments and services. Our holy grail is the second opinion, providing more information for both doctors and patients. For example, we can help with decision support in the area of CT scans by informing doctors about the risks of contrast media when the kidney function of a patient (Continued next page) ‘We care without distance’ By Prof. Val Crawford, TMU Outwards editor As this issue’s theme is “Connecting with research,” the other pages of this magazine are full of TMU’s research and the many ways our bench-to-bedside efforts translate ideas into better practice. So here I’d like to talk about connecting. Our title, TMU Outwards, refers to the global reach of this institution: the international students, visiting scholars, partner universities, outbound exchange students, service groups going abroad, and our medical missions that teach our students and staff while helping others. Still, when I looked up and saw “We Care Without Distance” bannered across TMU Hospital in huge letters, I was confused. What does this mean? Is it the quality of empathy that erases a clinical professional’s cool remove from pain, distress and death? Is it the home care, the mammogram-mobile and other programs that take our services to the community? Is it the satellite links that enable real-time medical exams for burn victims on the far side of Africa? I think the meaning is connection – because connection is our primary business. Education is connection, a message that (Continued from page 12) is impaired or unknown. We were able to prevent 200 cases of contrast media-induced kidney damage a year in one hospital. Helping patients take meds We can also provide decision support for patients. We have completed a three-year study of medication reminders for patients. Compliance is a huge problem. Half of all prescribed medication is not taken properly. Sometimes even when I prescribe for myself, I still miss times that I should take it. And the effect of this is bad for disease control, waste of resources and pollution to the environment, because we throw away these drugs and our rivers bridges a gap and changes a learner. These days that gap can be easily hurdled from any distance, and at any time, by our Open Course Ware (lab videos get heavy play at midnight during midterm weeks). Sometimes the greatest distance is invisible, only an arm’s reach away behind a wall of indifference. That’s what it feels like when students are playing on Facebook instead of engaging in classroom discussion – a common enough problem that “We Distantly Care” might be their slogan. But when we connect, we educate and help each other. With dozens of nations represented at TMU, cultural distances and differences are reliably unpredictable. Some students dislike criticism and speaking up; others learn best with competition and even conflict, if resolved with the rhetorical tools of civilized debate. Connecting is not about the easiest habits of conviviality, about reiterating what we know. It’s tempting to shut down when we leave our comfort zone. But becoming a scholar is like going to a very long academic conference: there are people to meet and ideas to encounter, and a limited amount of time to prove one’s worth, to justify the resources spent in sending us across the planet. n have been contaminated with sedatives and other chemicals. We know that compliance goes down with increased prescriptions. It’s estimated at 80% with one drug, but it drops to 20% with four meds. Taiwan’s average patient takes 4.4 medications, so 80% of these meds are taken incorrectly or incompletely. Yet in our trial of 1000 patients, reminders delivered through mobile phone messages cut the number of missed meds from 50% to 10%, and late or delayed dosages from 74% to 20%. This would be one of the examples that how appropriate use of simple IT intervention can have dramatic effect on the impact of healthcare. n 13 Table tennis helps TMU faculty put pressures aside Story and photo by Trista di Genova, United States A few years ago, Prof. Jung-shan “Jack” Chang created TMU’s Faculty and Staff Table Tennis Club.The Graduate Institute of Medical Sciences faculty member was recreating the golden years of his youth as a graduate student in the United States, but he had higher motives as well. “I just want people to be healthy,” he said during a recent Wednesday night in the United Medical Building basement. This informal workout was attended by TMU’s vice president and other academic notables. As my own unfinished thesis writing has me nearly “bouncing off the walls” as well, I often join this two hours of gleeful madness every week. In my case, at first being really rusty at table tennis, the priority was getting some hard action from the “ping-pong robot” or ball-serving machine. This robot is a glorious invention, since both the frequency and position of these robo-serves can be adjusted to wear down a player with a brisk pace or allow leisurely lobs. And the robot doesn’t mind if you prefer the ball to always land in one spot, or if you want the challenge of alternating right and left serves on this miniature tennis court. It’s a great workout. It makes you sweat and uses all your upper body muscles. “It also builds hand-eye coordination,” Prof. Chang explained as he helped coach a new member on a forehand return. Under his guidance, the faculty table tennis club now numbers thirty-plus members. Students can play in the same space (next to the food court) at any time during the rest of the week, or even take a class in table tennis to learn the finer points of the sport. This has paid off, because TMU’s players recently took a national award at the College Games in Ilan last month. When Prof. Chang was studying plant pathology in the States, he found the graduate student lifestyle afforded him plenty of time to return to a childhood interest in the art and sport of table tennis. The apex of his career was to be twice crowned champion of a New York-area competition for Taiwanese scholars. Now he just coaches for fun, but watch out if you face him in a game; he’s tough! (After all, he also keeps fit by riding his bike to TMU all the way from Xindian every day.) n Malawi must protect people from catastrophic medical spending (Continued from page 8) The recent enactment of a national registration system provides a window of opportunity to set up a national health insurance system. This will ensure that the people getting medical care are those who most need it, unlike the current system where anyone can receive treatment at no cost. The insurance system will also establish 14 a sense of shared responsibility to ensure hospitals respond to patients’ needs. This initiative requires a coordinated effort between public and private sectors to provide checks and balances, but it has worked in countries similar to Malawi – why can’t it work for us? n ‘Mother of cancer research’ tells her story (Continued from page 7) What do you think is a reason why more men are getting prostate cancer? We don’t really know much about prostate cancer, but we think it has something to do with steroid intake. Also, one’s diet has a lot to do with getting prostate cancer. In fact, I think a lot of cancers are related to food intake. I know in the past, you had faced discrimination in the science field for being a female. Has that changed now? For female scientists, they always say they have some discrimination. I think for example, even in America it is the same thing. Also when female scientists have a family, they need to have kids to think about. I do not blame women for putting family first. But I still think ability wise there is no difference between men and women. I think sometimes women are better because they are more concentrated. In fact, to look at a current gender divide, look at nursing. We have very few male students. The male nurses all end up going into the ER, ICU, and neonatal. If you want to discriminate, look at the nurses. A lot of male nurses are in ICU because of the time they get to spend in the department. However, overall, I think the medical field does not discriminate between genders. Everywhere has unfairness. Even in a group of females, there is still competition and inequality. There is always a problem. I never thought because I was a woman, I did not get what I was supposed to get. A lot of times, it is not because you are a woman. It is because you do not speak up. If you go there and display your passion, you will get what you want. Do you see any new developments in terms of cancer treatment besides chemotherapy? There is so much that has improved. Before, we had treatment that killed not only tumor cells but also healthy cells. Now we target the drug so it only kills the tumor cells. But it is an expensive drug. We also have immunotherapy. Immunotherapy is a preventive vaccine, such as the one for HPV (human papillomavirus). It is not only preventive but it can also kill tumor cell because it uses antibodies.Your tumor has a specific antigen that it presents so making an antibody model makes immunotherapy more effective. We hope that we can find a unique antigen on every tumor so can use the antibody to create vaccines so people will not get cancer. What do you think about the statistic that 70% of doctors would decline treatment if they had cancer? You see this trend when doctors have the end-stage cancer, not early stage. At end stage, doctors know they cannot stand chemotherapy. They cannot stand to take medication. So they think of taking alternative therapy, like Chinese medicine. That therapy tries induce your immune system so you don’t need medical treatment. They try to activate your chi [vital energy]. They use tai-chi, da-zhong, meditation. Maybe they will use herbal drugs or change your diet. How do you compare Taiwan’s health care to the rest of the world? For medical care, Taiwan is at the top. For example, last time I was in America, my husband was unable to get out of bed and we thought it was a stroke. Of course, they did all sorts of tests. But they did not find anything and we stayed in the hospital for three days. The bill from that was a shock. Even with health insurance from working at NIH, the bill cost a fortune. In Taiwan, I broke my hip in a fall and another time I had my gallbladder removed because of stomach problems. Do you know how much I paid for the care? Not even $20,000 NT, which is not even $1000 USD. Amazing. n 15 53rd anniversary sports day on June 1 Taipei Medical University 250 Wuxing St., Taipei 11031 Taiwan 16 Website: www.tmu.edu.tw/English/main.php Phone: +8862-2736-1661, ext. 2711 E-mail: iss@tmu.edu.tw Facebook: TMU Outwards n