Clinical Trials Of Kamdudha Vati In Mukhapak

ISBN 978-93-5173-179-3
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ISSN 2320-7329
Issue- 1st Jan- Mar 2015
Vol. 3
Ayurlog: National Journal of Research in Ayurved Science
A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved
Clinical Trials Of Kamdudha Vati In Mukhapak
__________________________________________________________________________
Nilakshi Pradhan*1
___________________________________________________________________________
1. Principal & Professor Department of Shalakya tantra, SSAM, Hadapsar, Pune-28,
Maharashtra.
* Corresponding Author: E-mail: drnspradhan@yahoo.com Mob-9423580963
___________________________________________________________________________
Abstract :
kamdudha only systemically. It may prove
Mukhapak is a commonest disease of mukha
better
found in India as well as all over the World.
administration of kamdudha.
combination than only systemic
In this condition mukha is affected by paka
process which is always associated with pitta
Key wards: Mukhapak, sarvsar, stomatitis,
dosha. Due to ulceration irritation, pain,
pratisaran, pitta prakop, ropan, daha.
burning sensation is experienced when
Introduction: The symptoms of Mukhapak
patient take food. Sometimes liquid intake
can be correlated with stomatitis. It is
also becomes troublesome as cold or hot
an inflammation of the mouth and lips. It
sensation gives lot of pain burning sensation
affects the mucous membranes of the mouth
etc. It is very important to have effective,
economic
& without
and lips, with or without ulceration. In widest
any side effect,
meaning, stomatitis can have a multitude of
medicine on it. Here an attempt to try
different causes. The commonest causes
Ayurvedic drug Kamdudha systemically as
which
well as locally as an application. It was
includes
infections,
nutritional
deficiencies, allergic reactions, radiotherapy
observed that healing rate of ulceration was
etc.[1]
fast in those patients who received kamdudha
by both the ways than who received
1
ISBN 978-93-5173-179-3
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ISSN 2320-7329
Issue- 1st Jan- Mar 2015
Vol. 3
Ayurlog: National Journal of Research in Ayurved Science
A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved
common in poor & uneducated class [5]. Also
Food is the factor which sustains &
supports the dhatu oja & bala i.e.strength or
alcohol
capacity to perform physical work. Food is a
chewing is very common in them. All the
basic requirement of the body. Food in any
above mentioned causes create stomatitis
form either liquid or solid is very essential
which is very common in our country [6].
for growth of body and maintenance of
consumption,
tobacco;
gutka
In modern medicine there is no
health. Restriction of food by any reason can
specific
create a serious condition. The disease
Combinations
mukhapak can occur if it is neglected or not
inflammatory are generally used in form of
treated properly
paste, gel or solution for gargles, which gives
Mukhapak is a common disease of the
oral cavity
[2]
treatment
of
for
antibacterial
stomatitis.
&
anti-
symptomatic relief by cooling soothing effect
[7]
. It affects patient’s daily
. As they are more in price also contains
routine. It is found more in pitta pradhan
side effects with them. Considering all the
dosh, pitta pradhan prakruti & pittaj kala. It
facts it is necessary to have effective, cost
is more found in India because people are
free drug which does not have any side
more prone to have pitta prakopak ahar like
effects. This project is devoted for the same
spicy oily food, tobacco chewing, smoking,
purpose & hence the following pages are the
alcohol consumption etc. and also pitta
result of this attempt.
prakopak
Aim & Objectives:
vihar like late night sleeping,

improper timing of meals etc. Due to the
paka process, ulcers & inflammation over
affected area is seen in mukha
[3]
to Ayurveda

.
There are various causes which create
.
Hence
directly
increasing
To study stomatitis according to
modern medical science

mukhapak like rapidly increasing problems
[4]
To study Mukhpak vyadhi according
poverty
To study the role of pratisaran
chikitsa & efficacy of kamdudha in
proportionally this has brought illiteracy, ill
Mukhapak vyadhi

health with it. Because of malnutrition
anemia stomatitis can occur. Bad hygiene is
To study the importance of systemic
effects of kamdudha in Mukhpak
one of the major reasons which are very
2
ISBN 978-93-5173-179-3
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ISSN 2320-7329
Issue- 1st Jan- Mar 2015
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Ayurlog: National Journal of Research in Ayurved Science
A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved
sensitivity & pain index is different the study
Methodology:
The study of this project is totally
was more based on clinical observations.
based on clinical observations & the patient’s
Duration of trial: The patients in the trial
narration. The patient selected for this project
group were treated systemically for duration
will be treated systemically with kamdudha
of 7 days treatment with kamdudha vati in
& locally with kamdudha churna pratisaran
the dose of 500 mg three times a day.
[8]
. This might prove that local application of
Whereas in control group, according to the
kamdudha churna along with systemic
severity of the disease, local application of
treatment enhances anti-inflammatory action
250 mg kamdudha churna 3 times a day.
& faster rate of healing with better results
[9]
.
Inclusion criteria: Inclusion criteria were
The yogvahi & vishaghna property of goghrit
done on the basis of randomization. This
will act as catalyst along with vranaropak
includes
and pittaghna property of gairik. Also
1. Age is no bar
tridoshaghna & vranaropak property of
2. Patients having ulcers in oral cavity
amalaki will help to enhance the properties
3. Patients ready for drug trial- patients
of gairik & thus anti-inflammatory action
were given an idea of the project
with ropan will be triggered
[10]
before giving the drug trial.
.
Group A- Trial group (total 30 patients)
These patients were
received
Exclusion criteria: The patients who could
systemic
not come for follow up regularly to outdoor
treatment of kamdudha with local application
patients OPD were excluded.
of kamdudha churna (pratisaran)
The patients who were selected for
Group B- control group (total 30 patients)
this project had a similar study method. As
These patients were received only systemic
mentioned earlier the study was totally based
administration with kamdudha
on the patient’s narrations & clinical
Design of study:
observations. The patients were given drug
An open comparative study was done
of seven days which was in form of tablet for
depending on the patients narration &
clinical
observations
as
oral ingestion & powder for local application
every patients
thrice a day. Follow-up was done every day.
3
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ISSN 2320-7329
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A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved
Elder person with the patient were advised to
in pitta pradhan desh ,pitta pradhan prakruti
give the drug regularly for seven days.
& in pittaj kala[11].
The subjective gradations of these
The occurrences of symptoms in
symptoms were done as follow & intensity of
both the groups were same. The symptoms
each system was calculated & was compared
relieved in the patients of both the groups
with that of other group i.e. control group.
were compared & also shown graphically. It
The subjective gradations of the symptoms
showed that kamdudha given systemically
was done as follows
with locally worked more effective in

Grade 0
- No pain
relieving all the symptoms than only

Grade +
- Mild pain
systemic administration of the drug.

Grade ++
- Moderate pain

Grade +++
- Severe pain

Grade ++++
In group A, result were found as
88% of patients had total relief of all the
symptoms on the 7th day. Total 3.3% patients
- Extreme pain
had no relief at all. In group B, 75% of
Similar graduation chosen for this
patients got relief on 7th day. 6.6% of
trial study was found commonly & which
patients had no relief.
was given a total idea of treating process.
Discussion:
Observations and Results:
In this study, efforts were made to use
From the study, it was observed that
Ayurvedic drug kamdudha which is cost
mukhpak is a common disease in all the age
effective & alternative treatment for modern
groups of present era. It is more common in
line of treatment of mukhapaka. The ratio of
young as pittapradhanyata found in young
male to female was 24:36.
age.
Stomatitis has become very common
Due to many reasons it occurs in
problem in the present era. It is very
mouth. In this disease mukha is affected by
important to have effective, economic &
paka procedure which is always associated
without any side effect, medicine on it. So
with pitta dosha. So mukhapak is more found
here an attempt is made to treat stomatitis
with kamdudha. As kamdudha is pitta
4
ISBN 978-93-5173-179-3
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ISSN 2320-7329
Issue- 1st Jan- Mar 2015
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Ayurlog: National Journal of Research in Ayurved Science
A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved
shamak in nature, it is useful to suppress
1. Text book of diseases of Ear-Nose-
pitta dosha. It also contains vranropan
Throat by K.B. Bhargav, S.K Bhargav,
property which helps in healing of ulceration
and T. M. Shah, 6th Edition, Chapter No.
faster. Kamdudha contains sheet (cooling)
37, Page No. 211.
property which helps to reduce burning
2.
sensation present over the affected area.
1984,
does not have any side effect. In fact as
sensation,
by
Agnivesh,
by
Yadavji
Chaukhamba
Trikamji
prakashana,
Varanasi, Edition: Reprint 2009, Chikitsa
haematinic. Also with the faster healing rate
burning
edited
Acharya,
gairik contains iron and proved as a good
ulcers,
samhita
Chakrapani Tika, Chaukhamba orientela
Unlike modern medicine kamdudha
of
Charak
shana 26, page No. 889
pain,
inflammation, dysphagia etc. reduced faster
3. Sushrut Samhita of Sushruta with
in those patients who received kamdudha
Nidan Sangraha commentary of Shri.
systemically as well as locally.
Dalhanacharya
Conclusion : From the given observations
Panjika of Shri. Acharya on Nidansthana,
we can come to the following conclusions:
edited by Yadavji Trikamji Acharya,

Nidanasthana 16, page No. 314
Mukhpak is one of the commonest oral
&
Nyaya
Chandrika
diseases in India.

Mukhpak is found in all the age groups.

Mukhpak is found more in pitta –prakruti
4. Madhav Nidan by Madhavkara- with
commentary
Vijayrakshit
persons.

Use
of
&
Madhukosh
by
Shrikanthadatta with
extracts from Atankdarpan by Vachaspati
Use of kamdudha in mukhpak is found to
Vaidya, edited by vaidya Yadhavji
be effective.

of
kamdudha
locally
Trikamji Acharya-1955
with
systemically is found more effective than
5. Text book of diseases of ear-nose-
only systemic administration.
throat by P.L. Dhingra. Page No. 202, 4th
Edition.
Reference:
5
ISBN 978-93-5173-179-3
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ISSN 2320-7329
Issue- 1st Jan- Mar 2015
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Ayurlog: National Journal of Research in Ayurved Science
A Web based quarterly online published Open Access peer reviewed National E-journal of Ayurved
6. Text book of diseases of Ear-NoseThroat:
Dhingra,
2nd
Edition,
9. Bhavprakash Nighantu (Indian Materia
B.I.
Medica)
of
Shri.Bhavmishra
Churchill Living Stone Publication at
Commentory by Dr. K. C. Chunekar,
New Delhi, Chapter no.42, Page No.215.
Edited by Dr.G.S.Pandey, 10th edition
7. Text book of diseases of Ear-Nose-
10.
Throat diseases by Dr. Mohammad
Ayurvedic
Maqbool, Jaypee
councils for research in Ayurved &
brother medical
publishers 1993, 6th Edition, Chap-41,
Pharmacopoeia
formulation
standards
by
for
central
Siddha. 1st Edition, 1990.
Page No.328.
11. Ashtang hridaya – with commentary
8. Rasyogsagar- Satippan with Hindi
of Arundatta & Hemadri Nirnay sagar
Tika
press- Bombay, uttarsthana 21, 22, Page
by
Vaidyapandit
Hariprappan
Sharma, Krishnadas Ayurved series-7,1st
No.855.
Part, Chap-Athkakaradi Rasayog 155,
Page No.260.
Cite this article:
Clinical Trials Of Kamdudha Vati In Mukhapak
Nilakshi Pradhan
Ayurlog: National Journal of Research in Ayurved Science-2014; 3(1): 1-6
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