It`s All About Balance: Emerging Biofilm Science
Transcription
It`s All About Balance: Emerging Biofilm Science
Earn 1 CE credit This course was written for dentists, dental hygienists, and assistants. It’s All About Balance: Emerging Biofilm Science Written by Stacy McCauley RDH, MS Abstract Throughout history, medicine and dentistry have continually evolved via advances in technology and research. Breakthroughs in science allow dental professionals the opportunity to practice in new and exciting directions. What if breakthrough research assessed the benefits of an oral care device beyond just the visual inspection of brushing outcomes? What if the use of a power toothbrush could change the composition of dental biofilm to benefit the patient’s oral health? Dental biofilms are one of the major contributing factors for both periodontal diseases and caries infections. Through emerging research, we now know not all dental biofilm is bad. Novel and compelling science from Philips Sonicare demonstrates the ability of Sonicare* to transition the biofilm composition from a pathogenic state towards a benign state and eventually to a beneficial state. These research findings could significantly impact self-care regimens and long-term oral health. New technologies in novel chairside diagnostic/assessment products will also be explored. Publication date: Feb. 2011 Expiration date: Jan. 2014 Learning Objectives: The course participants at the conclusion of the course will be able to: 1. Discuss the evolution of medicine and dentistry as it relates to treatment, prevention, and risk assessment paradigms. 2. Explain the current limitations of the clinical assessment indices utilized in dentistry today. 3. List the 2 biofilm associated diseases impacting Americans in epidemic proportions. 4. Describe the biofilm composition, potential for impact on oral and systemic health, and strategies for achieving dental biofilm balance. 5. Explain the novel research supporting biofilm balance as it relates to the Sonicare power toothbrush. 6. Discuss new chairside diagnostic/assessment tools currently available for dental practices. Author Profile Stacy McCauley, RDH, MS Stacy is a graduate of Kellogg Community College with 16 years of clinical practice experience. After completing her Bachelor of Science Degree at Siena Heights College in Adrian, Michigan she relocated to Chapel Hill, North Carolina to obtain her Master of Science degree in Dental Hygiene Education. She is a former clinical assistant professor at the University of North Carolina School of Dentistry, has published research in various dental hygiene journals, and has conducted clinical research. She currently serves on the editorial review board for Modern Hygienist magazine and the Journal of Dental Hygiene, and is a member of the American Dental Hygienists’ Association and North Carolina Dental Hygienists’ Association. Stacy is the Manager of Professional Education and e-Learning for Philips Sonicare in the Carolinas. Go Green, Go Online to take your course PennWell designates this activity for 1 Continuing Educational Credit Supplement to PennWell Publications This course was written for dentists, dental hygienists and assistants, from novice to skilled. Educational Methods: This course is a self-instructional journal and web activity. Provider Disclosure: PennWell does not have a leadership position or a commercial interest in any products or services discussed or shared in this educational activity nor with the commercial supporter. No manufacturer or third party has had any input into the development of course content. Requirements for Successful Completion: To obtain 1 CE credit for this educational activity you must pay the required fee, review the material, complete the course evaluation and obtain a score of at least 70%. This course has been made possible through an educational grant provided by Philips Sonicare. CE Planner Disclosure: Michelle Fox, CE Coordinator does not have a leadership or commercial interest with Orapharma, the commercial supporter, or with products or services discussed in this educational activity. Educational Disclaimer: Completing a single continuing education course does not provide enough information to result in the participant being an expert in the field related to the course topic. It is a combination of many educational courses and clinical experience that allows the participant to develop skills and expertise. Registration: The cost of this CE course is $39.00 for 1 CE credit. Cancellation/Refund Policy: Any participant who is not 100% satisfied with this course can request a full refund by contacting PennWell in writing. ineedce.com It’s All About Balance: Emerging Biofilm Science Program Overview Target Audience Throughout history, medicine and dentistry have continually evolved via advances in technology and research. Breakthroughs in science allow dental professionals the opportunity to practice in new and exciting directions. What if breakthrough research assessed the benefits of an oral care device beyond just the visual inspection of brushing outcomes? What if the use of a power toothbrush could change the composition of dental biofilm to benefit the patient’s oral health? Dental biofilms are one of the major contributing factors for both periodontal diseases and caries infections. Through emerging research, we now know not all dental biofilm is bad. Novel and compelling science from Philips Sonicare demonstrates the ability of Sonicare* to transition the biofilm composition from a pathogenic state towards a benign state and eventually to a beneficial state. These research findings could significantly impact self-care regimens and long-term oral health. New technologies in novel chairside diagnostic/assessment products will also be explored. The target audience for this course is Dentists, Dental Hygienists and Dental Assistants from novice to advanced professional. Author Bio & Contact Information Stacy McCauley, RDH, MS Stacy is a graduate of Kellogg Community College with 16 years of clinical practice experience. After completing her Bachelor of Science Degree at Siena Heights College in Adrian, Michigan she relocated to Chapel Hill, North Carolina to obtain her Master of Science degree in Dental Hygiene Education. She is a former clinical assistant professor at the University of North Carolina School of Dentistry, has published research in various dental hygiene journals, and has conducted clinical research. She currently serves on the editorial review board for Modern Hygienist magazine and the Journal of Dental Hygiene, and is a member of the American Dental Hygienists’ Association and North Carolina Dental Hygienists’ Association. Stacy is the Manager of Professional Education and e-Learning for Philips Sonicare in the Carolinas. Effective Date: February 1, 2012 Expiration Date: January 31, 2014 Format: Self Instructional - Text based Web Activity Stacy McCauley may be reached at: stacy.mccauley@philips.com Educational Objectives Recognition and Credits Upon completion of this course, the clinician should have a better understanding of: n Discuss the evolution of medicine and dentistry as it relates to treatment, prevention, and risk assessment paradigms. n Explain the current limitations of the clinical assessment indices utilized in dentistry today. n List the 2 biofilm associated diseases impacting Americans in epidemic proportions. n Describe the biofilm composition, potential for impact on oral and systemic health, and strategies for achieving dental biofilm balance. n Explain the novel research supporting biofilm balance as it relates to the Sonicare power toothbrush. n Discuss new chairside diagnostic/assessment tools currently available for dental practices. PennWell is an ADA CERP recognized provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. PennWell designates this activity for 1 credit hour of continuing education credits. 1 # ineedce.com It’s All About Balance: Emerging Biofilm Science Online Examination & CE Verification Form: Caution: Completing a single continuing education course does not provide enough information to give the participant enough information to give the participant the feeling that s/he is an expert in the field related to the course topic. It is a combination of many educational courses and clinical experience that allows the participant to develop skills and expertise. To receive credit for your participation in this course you will be required to complete the online program examination. To complete the online examination participants must be registered and signed-in to ineedce.com and have added the program to their user account (MyCE Archives). Once added to your user account, a Take Exam link will be displayed from within the MyCE Archives section of the website. Upon selection of the Take Exam link, participants are provided access to the online examination form. Once completed and submitted an immediate grade report will be displayed. All participants scoring at least 70% on the examination will receive a Letter of Credit (CE Verification Form) verifying 1 CE credit. Letters of credit may be viewed and printed immediately as well as accessed anytime in the future (24/7) from within the MyCE Archives user records page of this website. Not enough time to complete your online examination? No problem, online examinations may be completed anytime during the effective period of the program. Participants requiring more time to complete an examination may return to this website, sign-in and complete the online examination. Cancellation/Refund Policy: Any participant who is not 100% satisfied with this course can request a full refund by contacting PennWell in writing. Hardware and Software Requirements To access CME-University materials users will need: n A computer with an Internet connection. n Internet Explorer 7.x or higher, Firefox 3.x or higher, Safari 3.x or higher, or any other W3C standards compliant browser. n Adobe Acrobat Reader or Apple Preveiw. n Occasionally other additional software may be required such as Adobe Flash Player and/or an HTML5 capable browser for video or audio playback. Disclosure Declaration Presenter Disclosure: Stacy McCauley has no relevant financial interests with any products or services discussed in this presentation. Provider Disclosure: PennWell's Dental Group does not have monetary or other special interest in any products or services discussed or shared in this educational activity. CE Planner/Organizer, Michelle Fox does not have a relevant financial interests with any products or services discussed in this presentation. Image Authenticity: No images in this educational activity have been modified or altered. Scientific Basis: All content has been derived from references listed and the author’s clinical experience. Research references are provided in the bibliography and/or supplemental materials. # 2 ineedce.com It’s All About Balance: Emerging Biofilm Science Hello, and welcome to this virtual CE event. I’m your course facilitator, Stacy McCauley. One of the things I find most exciting and at the same time most challenging in dentistry is the daunting task of keeping current with the latest advances in research. One of the fastest growing aspects in the profession of dentistry’s evolving science is the area of emerging biofilm research. The concept of dental biofilms was pushed to the forefront in early 2000, in part by Philips Sonicare researchers and the research coming out of the Montana State University’s Center for Biofilm Engineering. Since that early research, both dentistry and medicine have both continued to grow the body of evidence. Let’s look at how closely medicine and dentistry are dovetailing their scientific advances. Medicine has its historical roots deeply seated in the treatment of diseases. The idea that doctors and medicine can fix whatever is ailing you has been commonplace for hundreds of years. As we all know, healthcare continues to struggle with getting patients to commit to compliance with proactive, preventive behaviors such as improved nutrition, healthier food choices, eliminating risky behaviors such as smoking, committing to regular exercise, even the idea that flossing daily improves your overall health. These behavior changes have all been identified as ways to help prevent a disease from manifesting. However, getting people to become committed to a healthy prevention-oriented lifestyle has been a challenge, to say the least. In a moment, we will also look at this scenario of disease treatment versus disease prevention as it relates to dentistry. And we’ll get to that in just a moment. Healthcare is now beginning to use risk assessment, which you see here in the third box. Risk assessment strategies are used to help identify those patients with significant risk factors. If risk factors are identified, then intervention can happen early, possibly early enough to prevent the disease from taking over the patient’s body. For now, if we look at the first box on the left on this slide, this depicts the medicine evolution. We see disease treatment as the foundation of medicine. 3 ineedce.com It’s All About Balance: Emerging Biofilm Science Historically, medicine used an approach of what I call “cleaning house” when it came to the treatment of various diseases and conditions. Specifically, with bacterial infections, individuals were routinely treated with broad spectrum antibiotics to completely obliterate the bacterial populations. This was based on the popular notion of the day that all bacteria was bad. That is demonstrated here on the left side of your slide. Historically, medicine wanted to eliminate all bacteria. Today, with the emergence of new science, we see medicine using antibiotics much more judiciously. Many in the medical community are not only embracing the fact that sometimes the body’s natural immune defenses are the best intervention. So, for example, that would be letting nature take its course to rid the body of infection through things like a fever. But the medical community is also dramatically changing their position on the use of antibiotics. Modern medicine, in part due to antibiotic overuse of the past decades, has dramatically changed the prescribing protocols when it comes to antibiotic prophylaxis and the use of antibiotics without a definitive diagnosis, meaning, before they even know if it’s a viral infection or bacterial infection. This is a major shift from the previous 20 years when physicians wrote prescriptions for antibiotics just in case they were dealing with a bacterial infection. So what you’ll see today on the slide on the right, the bacterial balance and management concept is the current paradigm compared to the paradigm of historical medicine, and that was total bacterial elimination. Dentistry, too, has evolved in the theories behind our clinical decision making. If you began practicing prior to the 1970s, now I doubt anyone was practicing when this picture was taken, but just for a perspective’s sake, if you practiced prior to the 1970s you likely focused your career on eradicating disease. Medicine did the same thing. In dentistry, it meant we were doing a great job of getting people healthy via intervention or treatment strategies only. This meant we extracted infected teeth or we filled decayed teeth. 4 ineedce.com It’s All About Balance: Emerging Biofilm Science Moving on, the 1970s through about the year 2000, dentistry began to add disease prevention into the standard of care. Dentistry started utilizing things such as topical and systemic fluoride to not only reduce current caries incidence but to also help prevent future disease. Dentistry also began to treat caries much earlier, thanks to the diagnostic assistance of bitewing radiographs. Now dentists could restore insipient lesion before it had a chance to spread deep through the enamel into the dentin. Sealants are yet another example of the post-1970s prevention-focused paradigm. Now if you look on the slide you can see the evolution of treatment-focused to prevention-focused and where we are today is in the final box. The final box is risk assessment and risk modification. Today is yet another opportunity for dentistry to once again advance its standard of care. We are not only treating disease; we are not only preventing disease; we are now predicting disease. This is the foundation of risk assessment. If we wait until evidence of disease is present, for many patients that is just simply too late. They are now in a cycle of disease that lasts a lifetime, regardless of our best efforts with prevention and treatment interventions. 5 ineedce.com It’s All About Balance: Emerging Biofilm Science If we look at dentistry, we have a progression in how we’ve viewed biofilm. If we look at historical dentistry, the total Plaque Elimination Model, which you see here on the left, was pretty much the mainstay. The total Plaque Elimination Model has now been deemed as old science because your patients will never be able to completely remove all the plaque anyway. Yet health is sustainable with incomplete plaque removal. I think all of us have seen cases in our practices of patients with less than stellar oral hygiene. They present for the dental hygiene appointment with moderate, even heavy plaque but interestingly, we don’t see a lot of inflammation; we don’t see a high bleeding index. So that’s to the point that just because the patient has biofilm present doesn’t necessarily mean they’re going to develop disease. And conversely, you can have patients with pristine oral hygiene and they present with absolutely a plaque-free mouth that day and they still have a presentation of a high bleeding index or a high gingival index. The understanding that there are good bugs and bad bugs has resulted in the current paradigm, the paradigm that most of us were practicing under until very recently. The current paradigm is called Biofilm Control, and that’s in the middle section of this slide. We are now understanding that the Biofilm Control Model is only seeing half the equation because the other half of the equation focuses on how to manipulate the surrounding biofilm environment to promote the good bacterial growth. Another aspect of the current approach seems to be a reactive approach in the fact that we are waiting for disease to happen before we intervene. The current paradigm of Biofilm Control, however, does differentiate the fact that there are good bugs in the biofilm and there are bad bugs in the biofilm and the current paradigm really focuses on eliminating the bad bugs only. If you move to the right side of the slide, this is the future paradigm and for those of you that are attending the webinar today, you’re some of the first dental professionals in the country to hear about the future paradigm, which is Biofilm Management. This is a proactive approach aimed at maintaining a healthy or health promoting oral balance, avoiding the tipping point into disease. Research is continuing to uncover the facets of biofilm composition. Some of the dental biofilm constituents aren’t just benign. The new paradigm goes further to say there are constituents that are actually beneficial and help keep the pathogenic bacteria at bay, thus maintaining a normal healthy oral flora. The biofilm management concept takes biofilm control one step further by not just focusing on removing bad bacteria, but also physically altering the ecological environment in such a way that growth and proliferation of good bugs is actually favored. Through actively promoting beneficial bacteria while keeping the pathogenic bugs suppressed, a healthy biofilm homeostasis is constantly maintained. The net effect of a balanced biofilm is long term oral health. This also supports the idea of probiotics. I think we’ve all seen the advertisements on television for the various probiotic products available on the market related to GI health. Dentistry is also starting to manufacture and use products that are based on probiotics, the idea of restoring oral balance. Our new treatment protocols will be using oral balance as a goal for achieving and/or sustaining oral health both for short term but also for attaining long term oral health. 6 ineedce.com It’s All About Balance: Emerging Biofilm Science Before we get into all of the cutting-edge science related to biofilm management, let’s take a look at one more piece of dental history. Traditionally, research has been measured via subjective outcomes assessments. Subjective outcomes assessments can be variable due to human interpretation. So what are we talking about? Well, it’s the clinical indices that we use almost on a daily basis with our patients. Things like plaque scores, probing depths, and bleeding index. A limitation of this traditional historical assessment protocol is the fact that it was limited in what it told us. It simply said if plaque was present or not. It does nothing to determine the pathogenicity of the plaque, or what we’re going to call dental biofilm, it also didn’t tell us what was happening on a cellular level regarding the immune response. Subjective analysis is also variable due to human interpretation. How many of you remember from dental hygiene school probing your patient’s mouth only to have your instructor come over and get completely different measurements? We both were doing the same technique but we got different outcomes - they’re subjective. Or bleeding index, or a plaque score. Science has shown us that traditional plaque studies have inherent flaws in their design based on their two dimensional representation of a three dimensional object. We have seen through confocal scanning laser microscopy that dental biofilm is actually three dimensional with a highly irregular surface. So, if we’re just simply using a plaque score it’s really not telling us the whole story. Just this information alone is enough to skew our outcomes. And when you combine the use of human subjects within plaque studies, the variability within each person’s plaque accumulation and their homecare behaviors can make for very weak research, repeatability and reliability. Now I want you to look at this picture of an iceberg. How many of you would say this is a huge iceberg? Go ahead, raise your hands. Now don’t you feel sort of silly raising your hands in the privacy of your own home? You can go ahead and put your hands down. 7 ineedce.com It’s All About Balance: Emerging Biofilm Science Now, what if I show you the real picture? The entire picture. Now I wonder how many of you think it’s a really huge iceberg. Traditionally, dentistry has just been able to see the tip of the iceberg when it came to assessing disease and/or health in our patients. If we limit our view of the patient to just what is visible on the surface, we are not seeing the entire picture. So another way to look at this from our day to day clinical perspective is this: you know, I wonder what’s under this patient’s iceberg. Or even further, what’s going on within this biofilm ecosystem. If we use traditional clinical assessment, I’m only seeing what’s on the surface. Clinically, I see evidence of pathogenic biofilm due to the obvious signs of inflammation and caries infection. Later in the program I will briefly introduce you to some of the newest chairside diagnostic items we can utilize to look below the surface into this biofilm to definitively determine what’s going on in the ecosystem. When we know what we are dealing with we have a better game plan on how to devise a plan for managing the biofilm and the disease process. 8 ineedce.com It’s All About Balance: Emerging Biofilm Science Clinically, we know a disease characteristic when we see it. You can see obvious signs of disease evident on the left photo. Additionally, we also assume, by clinical observation only, that after periodontal therapy this patient is now healthy as evidenced by the after picture on the right. But how do you really ever know if health is established in your patients after intervention? Moving beyond just our clinical subjective observations, what if we could know what was going on at a subclinical level, or below the surface of the tip of the iceberg? I showed you a version of this slide earlier in the program. I’d like to come back to the concept of subjective assessments and the added benefit of utilizing objective assessments as well. The iceberg analogy hopefully makes sense when we think about our traditional means of data gathering. We routinely gather information from our patients via medical history, visual inspection of the oral cavity, periodontal measurements, radiographic interpretation, and so on. Like the iceberg, if we don’t know what lies beneath, we do not have an accurate picture of our patients. So, what’s in the mouth, or the top section of this slide, those clinical endpoints are subjective. It does not tell us anything about what’s going on under the surface. Meaning, what sort of impact does our intervention therapy have or maybe what sort of impact does the oral care products I’m recommending have on my patients, other than just what I see present in the mouth? Sonicare has been at the forefront of moving beyond the traditional outcomes assessment into a new arena: Biomarker Assessment. So in addition to seeing the benefit of the intervention of the power toothbrush through traditional measurements, such as plaque score reduction, pocket depth reduction, the reduction of bleeding index, Sonicare is now adding the assessment of biomarkers to the research assessment criteria. Well, what is a biomarker? Well for example, gingival crevicular fluid samples – that’s a biomarker. And as we know, in patients with active periodontal disease and an inflammatory response, they have a higher gingival crevicular fluid flow. There are also opportunities for us to now use chairside diagnostic tools to not only do a microbiological or physiological assessment, but we also now have an opportunity to actually do a genetic assessment on our patients chairside. And we will talk about that in a few minutes. 9 ineedce.com It’s All About Balance: Emerging Biofilm Science Like medicine, dentistry historically took an allor-nothing approach when it came to treating infection via the total elimination approach. After focusing our energy on achieving a plaque-free mouth, we would think that we would have completely obliterated all bacteriarelated oral infections. So, how are we doing with that? Well, according to the American Academy of Periodontology, they estimate that 75% of Americans have some form of periodontal disease. So we look at our traditional paradigm of removing all of the plaque possible or the traditional model, it might not be working so well because we still have a majority of the population suffering from this biofilm associated disease. So we need to probably think about changing our paradigm. Another reason I think it’s important for us to sort of have a serious conversation with holding on to the historical plaque-free mouth approach, is the fact that we now see dental caries infections in our most vulnerable population - children ages 0-5 – at absolutely epidemic proportions in this country. I’m just going to read a few of these bullet points. I think they’re pretty shocking. Dental caries is the most common chronic childhood disease. It is more common than the common cold and it is five times as common as asthma. Three times more children have unmet needs for dental care than for medical care. One-fourth of children, by age four, will have experienced early childhood caries infection, and half of children by second grade. And you can see the breakdown on the final box on the slide, caries ages 2-5. In 1988-1994, 24% incidence and now that has jumped to 28% 1999-2004. I hate to see the next set of data statistics on this because I think we’re going to see yet another jump. So, periodontal disease is a biofilm-associated oral infection and dental caries infection is a biofilmassociated disease of the mouth. So the idea that we need to start changing our paradigm on how we approach biofilm management is of the most importance for us at this time. 10 ineedce.com It’s All About Balance: Emerging Biofilm Science Okay, so it’s time for a little history lesson. I’m going to ask you this question and I wonder what your response is going to be. Now, I think if anybody walked up on the street and asked you, as the dental hygienist, “Hey, how many times a year do I need to have my teeth cleaned?” probably most of us would have the knee-jerk response of, “Well, you should have your teeth cleaned every six months or twice a year.” But have you ever wondered how that protocol was ever established? I mean, I guess I just assumed somebody much smarter than myself established this protocol based on research or science. I was really shocked when I found out protocol for having a checkup and prophylaxis every six months was actually established in the 1950s on a radio commercial for Ipana toothpaste. They would sing this little jingle, “Brush-a, brush-a, brush-a, with the new Ipana” and the jingle would continue on and say “and see your dentist twice a year.” Well, folks, that is exactly how the six month Recall Prophy Frequency was established and I’m sorry to say in this year, we still are practicing based on the recommendations from a toothpaste commercial from the 1950s. So, if dentistry is going to move forward and not get stuck in tradition, we should start practicing based on risk assessment. Some patients with evidence of disease and multiple risk factors would need an evaluation and a preventative maintenance appointment maybe at every two or three months. Conversely, some patients with extremely low risk factors may absolutely do well with a preventative maintenance recall and exam at maybe every 12 months or 18 months. So again, if we stay stuck in our old traditions, we’re not practicing based on best evidence. The same thing rings true with how often you take bitewings? So many offices in the US still expose patients to bitewing radiographs no matter what, every 12 months. It doesn’t matter if the patient has a history of caries infection or not. Well, this is a time to take a look at what the American Dental Association said about four years ago. The ADA came out with a position paper on radiographic exposure and it said dentistry must stop exposing patients every 12 months to bitewings simply because insurance reimburses for it. It is important that we make our decisions based on patients’ individual risks. Low caries risk patients, the ADA says, every 18-36 months would be appropriate. Moderate to high risk patients, that may be every 6 months or every 9 months. So again, we need to move forward with new protocols. Think about recommendations of home care products. Probably many of you listening to this webinar personally use a power toothbrush because you know not only does the research support effectiveness, but you’ve tried it yourself and you know there is a significant difference in the brushing experience. But I’m going to ask you how many of you power brushers out there listening to this program are giving your patients a manual toothbrush every six months when they’re in for their preventative maintenance? I just encourage you to make recommendations and practice based on best evidence, not on tradition. And if you know it to be true in the research and you’ve experienced it yourself, why would you give your patient a substandard means of brushing? Let’s take a look at scaling and root planing. Dentistry is a very interesting bird, because we are the only profession that pre-determines the number of visits of therapy and we are assuming that after the last visit of therapy the patient will be healthy. Let me give you an example: if you have an injury and you go to a physical therapist to rehab your knee, I’m going to tell you I doubt anyone out there had the physical therapist look at their MRI and feel the knee at that first visit, and at that first visit the PT said, “Mr. Smith, I’m going to guarantee you I’m going to do four manipulations and four sessions of physical therapy and your knee will be healthy and you will be out of pain.” That’s not how it works. The physical therapist never pre-estimates when you will be done. You are 11 ineedce.com It’s All About Balance: Emerging Biofilm Science finished with therapy when your knee doesn’t hurt and when you’re fully functional. But that’s not what we do in dentistry. Open-ended therapy is a new approach. We don’t tell the patient when they are going to be finished. They are finished when we see no bleeding. They are finished when we see no pocket progression, and they are finished when they meet our criteria of health. Finally, dentistry is starting to move forward because we now are going to embrace the idea of biofilm management, not the idea that we need to eradicate all of the biofilm in the mouth. I’d like to walk you through this process. And this is a process we’re all very well familiar with. If you look at the picture on the upper left of your slide, this is a diagram showing biofilm on a tooth surface and in this case we have obviously an unhealthy composition of biofilm. Why do I say it’s obviously an unhealthy composition? Because look at how the tissue is responding. That biofilm is releasing unhealthy endotoxins. Now, you might have another patient presenting with just as much biofilm on their tooth but the biofilm probably doesn’t contain the pathogenic bacteria and the pathogenic bacterial byproducts. So they won’t have this response from the tissue. In this instance, you can see how we start to get tissue breakdown of the epithelium and this is the idea for how potentially, periodontal disease infections can play a role in systemic health. So if you think about the model of seeing a patient twice a year for their preventative maintenance or prophy appointment, if you look on the right side of the slide, I’m going to walk you through the rationale for why we need to modify or to support your current oral homecare procedures and protocols. If the patient comes in to see the dental hygienist twice a year, you think about an annual year – 365 days – so we have two days, two chances, to make a difference in that biofilm composition. Wouldn’t it be smart to get the patient an oral care device that has been proven to not only disrupt and dismantle the biofilm, but it’s also been shown in the research to encourage a healthy biofilm regrowth. And this is what you see here in the looping video on the lower right of the screen. This is the Sonicare brush being used in the mouth. It’s disrupting and dismantling the biofilm via mechanical bristle contact. So the brush strokes, extra soft, are brushing 31,000 brush strokes per minute, but the brush is also augmenting its effectiveness by the fact that it can patently move fluids in the mouth at a high enough velocity that it actually disrupts and dismantles the biofilm. In a moment, I’m going to show you some very interesting novel research that looks at the shift in biofilm composition. 12 ineedce.com It’s All About Balance: Emerging Biofilm Science This is one of the new products I mentioned at the beginning of the program relating to chairside diagnostics. This is the CariScreen caries susceptibility test and I think this is really innovative technology. Now, this product has several products in their lineup for maintaining a healthy oral balance for your at-risk patients, but for right now I want you to focus on the lower right of the screen where you see that little black device with the digital display. This test is very quick and is very painless. The clinician simply takes a swab sample of the biofilm or plaque from your patient’s teeth, and then you combine it with a special chemical agent. And then, you place that swab in that little black handheld device and it is going to give you a score between 0 and 9,999. A score under 1,500 is considered relatively healthy, while above that shows considerable risk for decay. This technology not only allows the clinician to measure the patient’s risk for decay today, but it also helps measure the progress as they follow the recommended protocols for reducing risk. So here’s where I see it really being a huge benefit chairside in a practice. To that second point about being able to follow the progress of the patient, you can easily track the benefit of the oral healthcare regimens you prescribe. So you would do an initial caries risk test and then you would continue to do caries screen risk tests after that. So, if the patient is using the prescription fluoride toothpaste, they are using their power toothbrush, you should absolutely begin to see a shift from their baseline of moderate to high risk to low risk. And I think, to me, that is such a teachable moment with our patients and it again supports the products that we are dispensing in the practice. So that could be xylitol products, that could be fluoride products, that could be power toothbrush products, and I think this is a great asset for us to have as a chairside diagnostic tool. 13 ineedce.com It’s All About Balance: Emerging Biofilm Science Saliva-Check Mutans is another chairside diagnostic tool. I think this is a really exciting piece of technology. It sort of looks like, if you look at the lower part of the screen, the test itself actually to me looks like a home pregnancy test. So, if we look at this patient with obvious biofilm control issues, if we took a sample of the biofilm and we could quickly mix it chairside and drop three drops into that chairside test, the test that sort of looks like a home pregnancy test, if you see the red line illuminate where the letter “T” is, that will tell you that you have a positive result. So if the patient has a positive result, it means the patient has a level of strep mutans equal or above 500,000 CFUs. The CariScreen product and the Saliva-Check Mutans are just two ways we can begin to incorporate objective analyses into our daily chairside protocols. And, for many offices, this is a nice addition to the hygiene services available to patients. It’s also a way to increase our revenue production. We saw this slide at the beginning of my program. How do you really know how much health was restored after your periodontal therapy? I mean, gosh, he looks good to me, but it doesn’t mean he’s no longer at risk. Even if things look okay today on the surface, again, we have to go back to the idea that we have no idea what’s going on below the surface or below the tip of the iceberg. 14 ineedce.com It’s All About Balance: Emerging Biofilm Science So another potential chairside diagnostic tool, so we can see below the surface, could be the use of the Oral DNA Labs product, MyPerio Path. What you see here on this slide, under the name John Doe, you will see the word “result.” And next to it in red lettering, the word “positive.” And it says five pathogenic bacteria reported above threshold. And it’s also telling us that the patient has a bacterial risk of “high” and it means very strong evidence of increased risk for attachment loss. So, if you go back to the previous picture I showed you of the before and after scaling and root planing or periodontal therapy, this is a way that we can actually assess the outcome of our periodontal therapy. And it will also help us reinforce our recommendations for not only periodontal therapy but the protocol for periodontal maintenance with our patients. Really great, new, novel technology. Some of you may be familiar with Dr. Jane Forrest’s evidence-based decision making model in the process of dental hygiene care, shown here on this slide. In this model, in order to practice based on current evidence, we have to embrace current scientific evidence, the client/patient preferences and values, the clinical or client circumstances, and also the dental professional’s personal experience and judgment. You don’t see anywhere on this slide the circle that says “History” or the circle that says “Because that’s the way I like to do it.” And that’s one of the pieces I hope that we can encourage all dental professionals to look at is, breaking out of tradition and breaking out of your comfort zone in order to practice based on best evidence. 15 ineedce.com It’s All About Balance: Emerging Biofilm Science Sonicare is the first power toothbrush company with research going beyond just the longstanding objective visual inspection to make its product claims. Let’s go into the future of dental research. Dr. Purnima Kumar from the Ohio State University is currently researching biofilm composition through objective assessments. Dr. Kumar and her research team were interested in understanding the process of shifts in microbial composition concurrent with the clinical changes following the routine use of the Sonicare power toothbrush. So they not only looked at our typical clinical indices like plaque reduction, bleeding index reduction, gingival index reduction, but they took it a step further to help move forward the science and they included objective analysis. In this research, she induced experimental gingivitis over a period of 21 days in a high-risk population of current smokers. Then, after 21 days, subjects were provided with the Sonicare toothbrush to use twice daily for two minutes for two weeks. I want you to take a look at the changes in the biofilm composition. So at baseline, meaning after they were induced into gingivitis at 21 days, when they did a baseline assessment the research team concluded that when they looked at the biofilm – they didn’t just look at how much biofilm was there, they said, “Let’s take it one step further and let’s see what lies beneath.” They found the explosion in growth of pathogenic bacteria in the biofilm. There was some growth in beneficial bacteria and there was slight growth in a category called “other bacteria.” Now, the patients went home, there was no dental hygiene intervention, no scaling or root planing, no periomaintenance, no prophylaxis. They went home and brushed with their Sonicare toothbrush for two weeks, twice daily for two minutes. When they returned to the research lab at Ohio State, they did another assessment of the biofilm. And again, they weren’t focused this time on how much biofilm did it remove, they were focused on what happened to the regrowth of the biofilm, or in this case, what’s the change in the biofilm composition? In just two weeks, that biofilm went from predominantly pathogenic to predominantly beneficial. The pathogenic bacteria was suppressed significantly. And you can see here we now have a much healthier biofilm composition. 16 ineedce.com It’s All About Balance: Emerging Biofilm Science If any of you are interested in learning more about beneficial biofilm and biofilm management, please visit sonicare.com/dp, “D” for dental, “P” for professional. As I conclude, I hope you feel a new sense of understanding on how to better address biofilm management with your patients. I think many times, we all get into a routine with patients and we unintentionally go on autopilot. We need a fresh perspective on how to uncover potential risk factors for both periodontal disease and dental caries infections; both biofilm-associated oral disease. I hope you feel compelled to not only reassess your assessment strategies when diagnosing and treatment planning patients based on what we talked about today, I hope you continue to work on evaluating and addressing factors that can potentially shift your patients from health to disease. It is all about balance and management. Remember to look well below the surface for what lies beneath. Remember the new science of biofilm management in order to achieve healthy biofilm balance. Remember that Sonicare is able to promote a healthy biofilm balance in just two weeks in a gingivitis population. If we remember all those things, we will not only attain oral heath today for our patients, but the goal of long-term oral health for all of our patients. I would like to thank you so much for participating in this webinar event. 17 ineedce.com It’s All About Balance: Emerging Biofilm Science Examination Review This page is provided for review only. To access the online post-exam you must be “Registered” and “Signed In.” and have completed the course selection/purchase process in its entirety. Once selected/purchased the course title will be added to your MyCE Archives page where a Take Exam link will be displayed directly across from the course title. A letter of credit will be issued upon successful completion of the post-exam with a score of 70% or higher. Please note: Credit may not be claimed if completed after the course expiration date. 1) Please indicate which of the following is not a component of the evidence-based decision making model: A) Patient preference B) Clinician judgment and personal preference C) Cost of product and/or treatment D) Research findings 2. All forms of biofilm are considered extremely pathogenic and must be completely removed in order to prevent oral diseases. A) True B) False 3. The American Academy of Periodontology estimates the incidence of periodontal diseases in the U.S. at 75% of the population. A) True B) False 4. Dentistry has evolved through many stages. Which of the following correctly describes the evolution of dentistry? A) Began with utilization of risk assessment, then focused on treatment of oral disease, currently focused on prevention of oral diseases B) Began with prevention of oral diseases, then focused on risk assessment, currently focused on treatment of oral diseases C) Began with treatment of oral diseases, then focused on prevention of oral diseases, currently focused on risk assessment 5. Which of the following is NOT considered a type of subjective assessment? A) DNA salivary analysis B) Plaque score C) Bleeding index D) Periodontal probing 6. Novel research demonstrated the ability of the Sonicare power toothbrush to alter biofilm composition in which way? A) Shift the bacteria in the biofilm from cariogenic to caries-preventing B) Shift the bacteria in the biofilm from gram negative to gram positive C) Shift the bacteria in the biofilm from pathogenic to beneficial in just two weeks 18 ineedce.com It’s All About Balance: Emerging Biofilm Science 7. What happens to gingival crevicular flow when a patient deteriorates from health to disease? A) Flow increases B) Flow decreases 8. The current paradigm of biofilm differs from the future paradigm of biofilm management in which ways? A) Current paradigm focuses on good bugs versus bad bugs B) Current paradigm focuses on eliminating bugs C) Current paradigm is not focused on allowing some bacteria to proliferate in hopes of creating a beneficial biofilm environment D) All of the above 9. Sonicare technology utilizes high speed bristle action along with ________ in order to achieve superior biofilm management. A) Electric pulses B) Multidirectional fluid forces C) Kinetic energy 10. The total plaque elimination paradigm has been extremely successful as evidenced by the complete elimination of dental caries infections and periodontal diseases in the U.S. A) True B) False 19