9 call for abstracts and registration 2 announceMent

March 16 –19 / 2015 / sliema / malta
advancements, applications
and theory in downstream processing
call for Abstracts and registration
2nd announcement
www.hic-rpc.org
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welcome Address
Dear Colleague,
On behalf of the Scientific Committee it is my pleasure to inform you that the
9th HIC/RPC Bioseparation Conference will be held in Sliema, Malta from March
16 –19, 2015. Sliema is located close to Valletta, the capital of the Republic
of Malta, the smallest member of the European Union. Malta International
Airport (approximately 10 km from Sliema) has daily direct flights to and from
the major European cities. On 316 square kilometers, Malta concentrates
splendid witnesses to an eventful history that goes back to the Bronze Age and
saw periods of Arabian, Italian, French and British dominance.
The HIC/RPC Conference series, which alternates between Europe and the US,
provides a unique forum for in-depth discussions on downstream bioprocessing.
It focuses on the increased scientific understanding of the hydrophobic nature
of biological targets and their chromatographic isolation and purification. The
program will put a special focus on current DSP topics such as antibody-drugconjugates or multimodal chromatography.
The Conference will seek to maintain an optimal balance of fundamental science,
engineering, and important industrial advances or applications. Recognized
professionals will provide insights into their areas of expertise. This combination
of knowledge and experience will lead to a deeper understanding of molecular
interactions and improved process design for biopurification steps. To encourage
young professionals to attend the conference, we have introduced a reduced
junior participant fee.
Visit the HIC/RPC Conference website – www.hic-rpc.org – for additional
conference details, such as registration information, call for abstracts, and other
informational updates.
On behalf of the scientific committee and the organizer, I invite you to this
exciting event, and we look forward to meeting you in Malta in 2015.
Cordially,
Professor Dr. Alois Jungbauer
Scientific Committee Chair
9th HIC/RPC Bioseparation Conference
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Table of contents
Scientific Committee....................................................................................................................... 4–6
Preliminary Scientific Program........................................................................................................... 7
Call for Abstracts.............................................................................................................................. 8–9
General Information..................................................................................................................... 10–11
Registration and Hotel Reservation......................................................................................... 12–13
Actively Involved Companies and Universities............................................................................ 14
Map of Malta / Sliema........................................................................................................................ 15
SCOPE
New ideas create improved solutions for downstream processing
The 9th HIC/RPC Bioseparation Conference is focused on the better understanding of
the hydro­phobic nature of biological targets and their chromatographic isolation and
purification.
The exchange of scientific ideas in a collegial atmosphere can create new approaches
and solutions for downstream purification steps. From basic theory to industrial scale
purification, recognized professionals will share their expertise and experiences on all
aspects of chroma­tographic separation and process design for biomolecules.
The practical elements of chromatographic development and implementation will be
balanced by panel and individual discussions about novel approaches and theories.
This combination will lead to a deeper understanding of the hydrophobic molecular
interactions affecting chromatographic selectivity and capacity, and the application of
this knowledge to large scale purifications.
SCIENTIFIC CONTENT
The program will consist of lectures and poster presentations contributed by scientists
worldwide. Recognized experts in industrial applications will present issues of topical
interest and lead discussions on a wide range of subjects.
Poster presentations and scheduled speakers will cover the following areas:
• Fundamentals of Hydrophobic Interaction and Multimodal Chromatography
• Industrial Applications of Hydrophobic Interaction and Multimodal Chromatography
• New Developments in Packing Materials and Operating Conditions
• New Antibody Formats and Antibody-Drug-Conjugates
• HIC for Bionanoparticle, Virus and VLP Purifications
The final program will be published in February 2015.
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Committee Chairperson
Alois Jungbauer
University of Natural Resources and Life Sciences
Vienna, Austria
Alois Jungbauer is Professor at the Department of Biotechnology. He is working in
the field of bioengineering of proteins, plasmids and viruses with a special focus on
expression, downstream processing and characterization of large biomolecules. His
international reputation is evidenced by his long record of scientific publications and
patents.
Committee Members
Tim Breece
Xoma Corporation
Berkeley, CA, USA
Tim Breece is currently a Senior Scientist in Purification Development at Xoma
Corporation in Berkeley, California, a position he has held since 2009. Here he develops
purification processes for monoclonal antibodies from the allosteric antibody research
program at Xoma. His main focus is in chromatography development, but his
respon­sibilities include all facets of downstream focusing. Prior to Xoma, Tim was at
Genentech for 24 years with positions in the Technology Assessment, Purification
Development and Manufacturing departments. He has a long track record of scientific
articles, presentations and patents. From 2002 – 2010, he served as an instructor for the
American Society of Mechanical Engineers Bioprocessing Technical Seminars lecturing
on chromatography scale-up and monoclonal antibody purification. He received his BS
in chemical engineering and applied biology from the University of California at Berkeley.
Jie Chen
Dyax Corporation
Cambridge, MA, USA
Jie Chen is Senior Director of Protein Science at Dyax Corporation. She joined Dyax
in 2000. Since then, she held several positions in process development and protein
science function areas. Jie currently leads the Protein Sciences team at Dyax for
process and formulation development, product characterization and preclinical research
lot production. She is also involved in overseeing the process tech transfer to GMP
manufacture contractors and GMP manufacturing activities for Dyax small protein and
antibody products. Prior to joining Dyax she worked in various biomedical research fields
and biotech companies, and also as clinical oncologist for several years.
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Committee Members (continued)
Steven M. Cramer
Rensselaer Polytechnic Institute
Troy, NY, USA
Steve Cramer is Professor of Chemical and Biological Engineering. He is conducting
research on several areas related to chromatographic bioprocessing with a long record
of scientific publications and patents. He has won numerous awards including the 2006
Alan S. Michaels Award for the Recovery of Biological Products.
Klaus Graumann
Sandoz GmbH
Kundl, Austria
Klaus Graumann holds a PhD in Biotechnology and joined Sandoz Biopharmaceuticals
in 2001. Since then, he held several positions in technical development of biopharmaceuticals for Sandoz and other divisions of Novartis. Since July 2010 he is Global Head
Technical Development Operations.
Milton Hearn
Monash University
Clayton, Victoria, Australia
Milton Hearn is Professor of Biochemistry and Director of the Centre for Bioprocess
Technology. His research interests have focused on the development and application
of new methods for biochemical analysis and separation with a long record of scientific
publications and patents. He has received various awards including the H.J. Smith Medal
of the RACI, the Japan Society for the Advancement of Science Award and the Alexander
von Humboldt Forschungspreis.
Thorsten Lemm
Roche Diagnostics GmbH
Penzberg, Germany
In his function as Head of Recovery & Downstream Process Development at Roche
Pharma Technical Development (Europe), Thorsten Lemm is responsible for downstream
process and technology development for biologics/large molecules. Thorsten received
his PhD in biochemistry in 1998 and has meanwhile accumulated 15 years of experience
in diagnostics and pharma biotech development at Roche.
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Committee Members (continued)
Egbert Müller
Tosoh Bioscience
Stuttgart, Germany
Egbert Müller is Technical Director at Tosoh Bioscience GmbH. He is a Lecturer in
Industrial Biotechnology at the University Darmstadt (Germany) and owns numerous
patents for surface modification techniques of chromatographic resins.
Arne Staby
Novo Nordisk A/S
Gentofte, Denmark
Arne Staby is the Senior Principal Scientist of CMC Project Planning & Management
at Novo Nordisk A/S. He obtained a PhD in Chemical Engineering from The Technical
University of Denmark, Department of Chemical Engineering in 1993, and after finishing
his post-doc in 1994 he has been working with development of purification processes
for recombinant proteins and peptides at Novo Nordisk A/S, both as scientist, specialist,
project manager, and department head. He has published and holds many papers
and patents. In 2009, he was appointed Adj. Professor in protein purification at the
department of Chemical Engineering, Lund University, Sweden.
Kouhei Tsumoto
The University of Tokyo
Tokyo, Japan
Kouhei Tsumoto is Professor at the Department of Bioengineering at The University
of Tokyo with a long record of scientific publications. He is working in the field of
bio­engineering and physical biochemistry with a special focus on antibody engineering,
artificial regulation of biomolecular interactions, disease-related molecular systems, and
protein engineering in bio-material design.
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PRELIMINARY SCIENTIFIC Program
Monday, March 16, 2015
12:00 –14:00
14:00 –14:15
14:15 –15:00
15:00 –15:30
15:30 –16:00
16:00 –17:30
19:00
Registration
Opening Remarks
Key Note Address
Fundamentals of HIC
Coffee Break
Industrial Applications of HIC
Dinner at the Hotel Palace
Tuesday, March 17, 2015
09:00 –10:30
10:30 –11:00
11:00 –12:30
12:30 –14:00
14:30 –23:00
Fundamentals of Multimodal Chromatography
Coffee Break
Industrial Applications of Multimodal Chromatography
Lunch
Excursion to Valletta and Dinner in M’dina
Wednesday, March 18, 2015
09:00 –10:30
10:30 –11:00
11:00 –12:30
12:30 –14:00
14:00 –15:30
15:30 –16:00
16:00 –17:30
19:00 –21:30
Fundamentals of HIC & Multimodal Chromatography
Coffee Break
New Antibody Formats & Antibody-Drug-Conjugates
Lunch
Round Table Discussion
Coffee Break
Industrial Case Studies
Poster Session & Buffet
Thursday, March 19, 2015
09:00 –10:30
10:30 –11:00
11:00 –12:30
12:30
New Developments in Packing Materials and Operating Conditions
Networking Coffee Break
Bionanoparticle, Virus, and VLP Purifications
End of Conference
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Call for Abstracts
Deadline: november 4, 2014
Abstracts on the aspects of separation of biomolecules will be accepted (see topics
on page 9). Oral or poster presentations are welcome.
Abstracts may only be submitted via Internet at the conference website
www.hic-rpc.org
For the preparation of your abstract, please refer to the guidelines on the conference
website. If you have difficulties in submitting your abstracts or you need further
information, please contact the Abstract Hotline: +41 61 686 77 22
(Monday – Friday during CET business hours).
Language
Abstracts must be submitted in English.
Presentation Format
Accepted abstracts are to be presented either as poster or oral presentation. The final
decision of the presentation format will be made by the Program Committee. Full
instructions concerning the preparation and presentation will be provided at the
beginning of December 2014.
Publication
Accepted abstracts will be published in an abstract booklet to be distributed at the
conference to all registered participants.
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CALL FOR ABSTRACTS (continued)
Deadline: November 4, 2014
Abstracts can be submitted for one of the following seven main topics:
1)Fundamentals of Hydrophobic Interaction Chromatography
2)Fundamentals of Multimodal Chromatography
3)Industrial Applications of Hydrophobic Interaction Chromatography
4)Industrial Applications of Multimodal Chromatography
5)New Developments in Packing Materials and Operating Conditions
6)New Antibody Formats and Antibody-Drug-Conjugates
7)HIC for Bionanoparticle, Virus and VLP Purifications
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General Information
Conference Language
The official language of the conference is English. No simultaneous translation will be
provided.
CONTACT
Scientific Secretariat
Regina Römling
Tosoh Bioscience GmbH
Zettachring 6
70567 Stuttgart
Germany
Administrative Secretariat
Nicole Hausmann
HIC / RPC 2015
c/o Congrex Switzerland Ltd
Peter Merian-Strasse 80, Postfach
4002 Basel
Switzerland
Phone:+49 711 13 25 70
Fax: +49 711 13 25 789
hic-rpc@tosoh.com
www.tosohbioscience.com
Phone:+41 61 686 77 77
Fax: +41 61 686 77 88
hic-rpc@congrex-switzerland.com
www.hic-rpc.org
DATE
March 16 –19, 2015
The conference will be held over 4 days, beginning with registration followed by the
1st session at 2 pm on Monday, March 16, 2015.
Scientific and technical presentations will be held from Monday afternoon, 2 pm,
to Thursday noon, March 19, 2015. Poster presentations are scheduled for Wednesday
evening. There will be an off-site event including dinner on Tuesday afternoon.
excursion
The excursion will take you to Valletta – the capital city of Malta. Valletta has many titles,
all recalling its rich historical past: it is the “modern” city built by the Knights of St John;
a masterpiece of the baroque; a European Art City and a UNESCO World Heritage City.
After some time off for leisure in the city center the excursion continues to the medieval
city of M’dina where the dinner will take place.
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General Information (continued)
Venue
The 9th HIC/RPC Bioseparation Conference will be held in Sliema, Malta. The conference
venue will be the Hotel Palace.
Malta is the biggest Island of the Maltese Islands and lies in the center of the
Mediterranean Sea.
Temperatures usually begin to rise in Malta in March and during this month, the average
temperature for the island is from 13°C in up to 15°C. The average sea temperature for
Malta in March is 16°C.
REACHING MALTA
The island is a few hours’ flying time from most mainland European cities and has
excellent intercontinental connections. Malta International Airport is located 10 km
from Valletta and 10 km from Sliema. The national airline, Air Malta, operates flights to
and from all the major airports in Europe, North Africa and the Middle East.
Getting Around
The small size of the Maltese Islands makes getting around easy and hassle-free. There
are various ways to get around in Malta. The public bus service is reliable and serves the
major tourist areas.
Ferries serve between Sliema and Valletta on a 30 minute schedule and taxi services
offer fixed rates from Malta Airport to Sliema (see also below).
For additional information please visit www.visitmalta.com/en/getting-around
Reaching Sliema
By Taxi
Taxi service is available 24 hours a day from Malta International Airport to any destination
in Malta. Fixed rates are applicable and pre-paid tickets can be purchased from the ticket
booth inside the Welcomers’ Hall on Arrivals.
Fare: € 20 (fixed rate from airport to Sliema)
For additional information please visit
gettinghere.maltairport.com/en/white-taxi.htm
By Public Transport
The public bus service is reliable and serves the major tourist areas. To reach Sliema
from the airport by bus, you must change bus lines in Valletta which may be difficult for
inexperienced travelers. The organizers therefore recommend to use taxi service at the
fixed rate (see above).
For additional information please visit www.visitmalta.com/en/public-transport
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Registration and Hotel Reservation
Please register online on the conference website: www.hic-rpc.org
All inclusive
conference fee covers registration,
hotel accommodation, excursion, and meals
Early registration
The deadline for early registration is December 12, 2014.
Registration Fee
until 12.12.2014
as from 13.12.2014 Conference fee includes
€ 2200
Participants
€ 1500
Students*
€ 1800
Junior
participants**
(born after 1980)
€ 2600
€ 1900
€ 2300
Accompanying
persons
€ 700
€ 700
Access to all scientific sessions,
hotel accommodation in a
single room for three nights***,
full board during the
conference, and the excursion
to Valletta and dinner in
M’dina.
Accommodation in a
double room for three
nights***, full board during the
conference, and the excursion
to Valletta and dinner in
M’dina.
*** A copy of official documents is required.
*** Junior participants must be born after 1980. A copy of official documents is required.
*** from March 16 –19 (3 nights) at the Hotel Palace
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Registration and Hotel Reservation
Hotel Accommodation
Participants will be accommodated at the Hotel Palace, Sliema (5-star). Extra nights
before and after the conference can be booked for € 130 while registering for the
congress. Please do not contact the hotel directly.
Confirmation
Upon receipt of the full registration fee, each participant will receive a confirmation of
registration. Please present this confirmation at the registration desk as proof of your
registration.
Cancellation/Name Change
Refund of fees, less 25% administrative charges, can be applied for in writing up to
February 10, 2015. After this date no refund will be possible. For any change of names,
a fee of € 20 will be charged.
Responsibility
The participant acknowledges that he/she has no right to lodge damage claims against
the organizers should the holding of the conference be hindered or prevented by
political events (such as acts of terrorism, danger of hostility, war etc.) or by unexpected
economic events or generally by force majeure, or should the non-appearance of speakers
or other reasons necessitate program changes. With registration, the participant accepts
this proviso.
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Actively involved companies and universities
Dyax Corporation (Cambridge, MA, USA)
Monash University (Clayton, Victoria, AUS)
Novo Nordisk A/S (Gentofte, DK)
Rensselaer Polytechnic Institute (Troy, NY, USA)
Roche Diagnostics (Penzberg, DE)
Sandoz GmbH (Kundl, AT)
TOSOH Corporation, Bioscience Division (Tokyo, JP)
University of Natural Resources and Life Sciences (Vienna, AT)
University of Tokyo (Tokyo, JP)
Xoma Corporation (Berkeley, CA, USA)
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map of malta / sliema (hotel palace)
Hotel Palace
Sliema
Airport
The Palace, High Street, Sliema, SLM 1542, Malta
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The 9th HIC/RPC Bioseparation Conference
is coordinated by:
TOSOH BIOSCIENCE GmbH
Zettachring 6
70567 Stuttgart
Germany
For further information,
please call +49 711 13 25 70
or e-mail hic-rpc@tosoh.com
Follow us on:
www.facebook.com/hicrpc
www.linkedin.com/groups/HIC-RPC-Bioseparation-Conference-8185008
www.hic-rpc.org