Bench and Bed Immunology 2015

BenchandBedImmunology2015
Thursday,15‐Jan‐2015
9:00 9:40–10:00 10:00–10:40
10:40–11:20
11:20–12:00
12:00–12:40
12:40–14:00
14:00‐15:00
15:40–16:40
RegistrationandWelcome
Presentationoftheseminar
ReinhardVoll,Freiburg
Primary(PID)andsecondaryimmunodeficiency(SID):
clinicalproblemanddiagnosticapproach
JeanLouisPasquali,Strasbourg
PredominantBcelldeficiencies
Blymphocytedevelopment
PaulineSoulas‐Sprauel,Strasbourg
Agammaglobulinemia
MartaRizzi,Freiburg
Hypogammaglobulinemia,CVID
KlausWarnatz,Freiburg
Lunch
Secondaryimmunodeficienciesduetodrugs
BlockingofTNF,IL1,IL6,..‐AndreasSchwarting,Mainz
Steroids,HCQ,MTX,AZA,MMF..‐JensThiel,Freiburg
Workshop:Bcellsimmunodeficiencies
Chair:ThierryMartin,Strasbourg
 ImmunosuppressiveroleofTrib1,L.Simoni,Strasbourg
 Towardssingle‐locusproteomicstorevalthemechanismsof
genomestabilityandDNArecombinationinBcells,L.Gaudot,
Strasbourg
 SearchingfornewgeneticmutationsinCVID,J.Kemmig,
Freiburg
Thursday,15‐Jan‐2015
16:40–17:40
Workshop:Secondaryimmunodeficiencies
Chair:AndreasSchwarting,Mainz,NilsVenhoff,Freiburg
SecondaryimmunodeficiencybyRituximab,N.Venhoff,Freiburg
 BcellsimmunodeficienciesduringHIVinfection,J.Tricallotis,
Strasbourg
 CTLA‐4‐Igtreatment,J.Tkocz,Freiburg

17:40‐19:00
Postersessionwithcoffee,reactivenetworking
Chair:MartaRizzi,AlesJandaFreiburg,Anne‐SophieKorganow,
Strasbourg
 PI3Kdeficiencies,M.Martin,Strasbourg
 ImmunereconstitutionafterHST,K.Piszcelskka,Strasbourg




20:00

SIDbymyeloma,J.Udi,Freiburg
SCID,R.Rothenberger,Heidelberg/Lausanne
TACIandCVID,Z.Escandaryan
TheAirWayInfectionSusceptibility(AWIS)study:an
epidemiologicalstudytocharacterizeinfectionprone
individualsatpopulationlevel,L.Maccioni,Freiburg
TheAWIS‐Score:AnApproachtoDetermineSusceptibilityto
InfectionsintheGeneralPopulationM.Bäurle,Freiburg
Immunoglobulinglycosylation,S.Schaffer,Freiburg
Diner
Friday,16‐Jan‐2015
8:30–9:10 9:10–9:50 9:50–10:30 10:30–11:00
11:00‐11:40
11:40–12:20
12:20‐13:00
13:00–14:20
14:30‐15:40
PredominantTcelldeficiencies
Tcellactivationandsignalling
WolfangSchamel,Freiburg
SCID‐Tcellimmunodeficiency
SebastianFuchs,Freiburg
Cytotoxicitydeficiencies(HLH,MAS)
StefanEhl,Freiburg
Coffeebreak
OthercausesandmanifestationsofPID
Cytokinespathwaydefects
AnneSophieKorganow,Strasbourg
AutoimmunemanifestationsinPID
BodoGrimbacher,Freiburg
TLRsdefects
FrédéricGros,Strasbourg
Lunch
Workshop:Tcellsdefects
Chair:AlesJanda,Freiburg
 RoleofmacroautophagyinTcellfunction,D.Murera,
Strasbourg
 HBVspecificCD4+Tcell:CharacterizationandroleofOX40,
F.Jacobi,Freiburg
 TcellexhaustioninchronicHepatitisBandC,P.Müller,
Freiburg
 IdentifyingmodifiersinCTLA4deficiency,C.Schwab,Freiburg
Friday,16‐Jan‐2015
15:40‐16:40
16:40‐17:00
17:00‐18:00
18:00‐19:30
20:00
Workshop:PIDImmunityatbarriers
Chair:PaulineSoulas‐Sprauel,Strasbourg,BodoGrimbacher,
Freiburg
Introduction:MucosalImmunity,BodoGrimbacher
 Inflammatoryboweldisesase‐microbiomeandgenetics,
S.Jendrossek,Freiburg
 LunginvolvementinCVID,I.Tröster,Freiburg
Coffeebreak
Workshop:Innateimmunitydefects
Chair:FrédéricGros,Strasbourg
 NKcellsimmunodeficiency,M.Sawaf,Strasbourg
 CARD9deficiency,F.Danion,Strasbourg
 Autophagyimmunodeficiency,J.Arnold,Strasbourg
 InnateimmunityinLupus,T.Aschman,Freiburg
Discussion
Diner
Saturday,17‐Dec‐15
8:30‐9:00
9:10–9:50 9:50‐10:30 10:30‐11:00
11:00–12:00
12:00‐13:00
13:00
13:15
ImmunereplacementandimmunomodulationbyIVIg/SCIg
Hans‐HartmutPeter,Freiburg
Hematopoieticstemcelltransplantation(HSCT)
BrigitteStrahm,Freiburg
ImmunereconstitutionafterHSCT
ThierryMartin,Strasbourg
Coffeebreak
Workshop:Immunedeficienciesandautoimmunity
Hanns‐MartinLorenz,SophieJung,Strasbourg
 Thrombopeniaandimmunodeficiencies,A.Guffroy,
Strasbourg
 Stromacellsimmunodeficiencies,A.Farouk,Strasbourg
 NewgeneticdefectsinPIDandimmunedysregulation,
J.Raabe,Freiburg
 Complementactivatedcell‐boundproductsinSLE,
J.Beckmann,Freiburg
Workshop:PIDandtherapies
ChristophFiehn,Baden‐Baden
 IVIgandkidneytransplantrecipient,M.Joly,Strasbourg
 Genetherapyandimmunodeficiencies,D.Bouis,Strasbourg
 Modulationofderegulatedchaperone‐mediatedautophagyby
P140peptideinLupus,F.Wang,Strasbourg
 Endothelialcellsplayanactivetoleinthymicregenerationvia
BMP4signaling,T.Wertheimer,Freiburg
Closing
AnneSophieKorganow,Strasbourg,ReinhardVoll,Freiburg
Lunch
SPEAKER:
KORGANOW,Anne‐Sophie
VOLL,Reinhard
EHL,Stefan
FIEHN,Christoph
FUCHS,Sebastian
GRIMBACHER,Bodo
GROS,F
JANDA,Ales
JUNG,S
LORENZ,Hanns‐Martin
MARTIN,Thierry
PETER,HansHartmut
PASQUALI,JeanLous
RIZZI,Marta
SCHAMEL,Wolfgang
SCHWARTING,Andreas
SOULAS‐SPRAUEL,Pauline
STRAHM,Brigitte
THIEL,Jens
VENHOFF,Nils
WARNATZ,Klaus
ADMINISTRATION:
AGENAIS,Silvie
WÜNSCHE,Inge