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January-March 2015 Volume 9 Number 1 ISSN 0973-614X
­Editors-in-Chief
Asim Kurjak (Croatia)
Frank A Chervenak (USA)
Donald School Journal of
Ultrasound in
Obstetrics and
Gynecology
The Official Journal of the
Ian Donald Inter-University School of Medical Ultrasound
www.jaypeebrothers.com
www.jaypeejournals.com
Donald School Journal of
Ultrasound in
Obstetrics and
Gynecology
1. Aims and scope
The Donald School Journal of Ultrasound in
Obstetrics and Gynecology publishes quality
review articles of all aspects of ultrasound as
it impacts diagnosis and management in the
field. As the technology and its applications
are constantly improving, there is a need for
lifelong learning for all sonologists so that they
can optimize their care of gynecologic, maternal
and fetal patients on an ongoing basis.
The Ian Donald Inter-University School of
Medical Ultrasound with its 50 active member
nations is proud to suppor t. The Donald
School Journal of Ultrasound in Obstetrics and
Gynecology and provide continuing medical
education to sonologists throughout the world.
2. Ethical considerations
Manuscripts submitted for publication must
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Informed consent
Informed consent of the patients must be taken
before they are considered for participation in
the study. Patient identifying information, such as
names, initials, hospital numbers or photographs
should not be included in the written descriptions.
Patient consent should be obtained in written and
archived with the authors.
Protection of Human Subjects and
Animals in Research
When conducting experiments on human
subjects, appropriate approval must have been
obtained by the relevant ethics committees. All
the procedures must be performed in accordance
with the ethical standards of the responsible
ethics committee both (institutional and national)
on human experimentation and the Helsinki
Declaration of 1964 (as revised in 2008). When
reporting experiments on animals, authors must
follow the institutional and national guidelines for
the care and use of laboratory animals.
ii
3. Copyright
Following guidelines must be followed before
submission of the manuscript:
The articles must represent original research
material, should not have been published before
and should not be under consideration of publi­
cation elsewhere. This, however, does not include
previous publication in form of an abstract or as
part of published literature (review or thesis). It is
the duty of the author to obtain the necessary
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the article has been accepted for publication.
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Both the conflict of interests and financial
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DSJUOG
Donald School Journal of
Ultrasound in Obstetrics and Gynecology
January-March 2015 Vol. 9 No. 1
Editors-in-Chief
Editorial Board
Asim Kurjak Croatia
Frank A Chervenak USA
Sameer Abdullah Saudi Arabia
Executive Editors
Sanja Kupesic Plavsic USA
Ritsuko K Pooh Japan
Ivica Zalud USA
Waldo Sepulveda Chile
Panagiotis Antsaklis Greece
Tuangsit Wataganara Thailand
Co-Editors
Kazuo Maeda Japan—History
Ana Bianchi Uruguay—Obstetrics
Giovanni Monni Italy—Invasive diagnostic procedures
Zoltan Papp Hungary—Prenatal diagnosis
Eberhard Merz Germany—3D/4D sonography
Veljko Vlaisavljevic Slovenia—Human reproduction
Miroslaw Wielgos Poland—Education
Radu Vladareanu Romania—Gynecology
Milan Stanojevic Croatia—Neonatology
Narendra Malhotra India—Developing countries
Carmina Comas Gabriel Spain—Echocardiography
Aris Antsaklis Greece—Twins
Ashok Khurana India—Urogynecology
Waldo Sepulveda Chile—1st trimester screening
Nelson Aguilar Colombia
Vincenzo D’Addario Italy
Tony Duan China
Alaa Ebrashy Egypt
Sebija Izetbegovic Bosnia and Herzegovina
Orion Gliozheni Albania
Alfredo Guzman Peru
Tze Kin Lau Hong Kong
Aleksandar Ljubic Serbia
Abdal-Latif Ashmaig Khalifa Sudan
Berivoj Miskovic Croatia
Oliver Vasilj Croatia
Anton Mikhailov Russia
Azen Salim Indonesia
Cihat Sen Turkey
Yuriy P Vdovychenko Ukraine
Liliana Voto Argentina
Hari Shrestha Nepal
Alexandra Matias Portugal
Syed Amir Gilani Pakistan
Corazon Yabes-Almirante Philippines
Abdallah Adra Lebanon
Mohamed S Elmahaishi Libya
Fawaz Akhazaleh Jordan
Publishing Center
Jiri Sonek USA
Publisher
Jitendar P Vij
Yaron Zalel Israel
Associate Director
Chetna Vohra
Managing Editor
Ekta Aggarwal
Editorial Associate
Pankaj K Singh
Creative Designer
Radhe Shyam Singh
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iii
Ian DONALD SCHOOL directors
Country
School Directors
Asim Kurjak
Frank A Chervenak
Vice-Director
Eberhard Merz
Regional Directors
Jaideep Malhotra (Indian Subcontinent)
Ritsuko K Pooh (Asia and Oceania)
Giovanni Monni (Europe)
Ana Bianchi (Latin America)
Abdallah Adra (Arabic World)
Executive Board
Sanja Kupesic Plavsic (Chairman)
Ritsuko K Pooh
Ivica Zalud
Panagiotis Antsaklis
Waldo Sepulveda
Milan Stanojevic
Tuangsit Wataganara
Advisory Board
Giampaolo Mandruzzato (Chairman)
Jose Maria Carrera
Gian Carlo Di Renzo
Joachim Dudenhausen
Toshiyuki Hata
Kazuo Maeda
Sonal Panchal
Directors of National Branches
Sameer Abdullah
Abbas Aflatoonian
Muna Al Kuwari
Ghalia Gaber Abd El Mottaleb
Nelson Aguilar
Mandy Abushama
Saadia Amour Sultan (Al Riyami)/Kanchana Rajan
Aris Antsaklis
Shahana Afroz
Ana Bianchi
Carmina Comas/Bernat Serra
Pavel Calda
Vincenzo D’Addario
Giovanni Monni
Tony Duan/Chen Min
Alaa Ebrashy
Sebija Izetbegovic
Orion Gliozheni
Erasmo Huertas Tacchino/Alfredo Guzman
Tze Kin Lau
Aleksandar Ljubic
Ritsuko K Pooh
Abdal-Latif Ashmaig Khalifa
Narendra Malhotra/Jaideep Malhotra
Sonal Panchal
Ana Tikvica Luetic/Oliver Vasilj
Anton Mikhailov
Alexander Papitashvili
Zoltan Papp
e-mail address
Croatia
USA
asim.kurjak@public.carnet.hr
fac2001@med.cornell.edu
Germany
emerz@mail.uni-mainz.de
USA
Japan
USA
Greece
Chile
Croatia
Thailand
sanja.kupesic@ttuhsc.edu
pooh27ritsuko@fetal-medicine-pooh.com
ivica.zalud@gmail.com
panosant@gmail.com
waldosep@yahoo.co.uk
milan.stanojevic@optinet.hr
twataganara@yahoo.com
Italy
Spain
Italy
Germany
Japan
Japan
India
mandruzzatogiampaolo@tin.it
jmcarrera@matres-mundi.org
direnzo@unipg.it
joachim.dudenhausen@charite.de
toshi28@med.kagawa-u.ac.jp
maedak@mocha.ocn.ne.jp
sonalyogesh@yahoo.com
Saudi Arabia
Iran
Dubai, UAE
Abu Dhabi, UAE
Colombia
Qatar
Oman
Greece
Bangladesh
Uruguay
Barcelona, Spain
Czech Republic
Bari, Italy
Cagliari, Italy
China
Egypt
Bosnia and Herzegovina
Albania
Peru
Hong Kong
Serbia
Japan
Sudan
India
Ahmedabad, India
Croatia
St Petersburg, Russia
Georgia
Hungary
samirabdullah@hotmail.com, drsabdullah@gmail.com
abbas_aflatoonian@yahoo.com
muna.alkuwari@yahoo.com
ghgaber@gmail.com
nelsonyesid@gmail.com
mdabushama@hotmail.com
drsaadiaalriyami@gmail.com/raajaan@omantel.net.om
arisants@otenet.gr
nmcdhaka@agni.com
anabbianchi@gmail.com
carcom@dexeus.com/BERSER@dexeus.com
calda@gynstart.cz
v.daddario@gynecology4.uniba.it
prenatalmonni@tiscali.it tduan@yahoo.com/chenm@cuhk.edu.hk
ebrashy3@yahoo.com
s.izetbegovic@gmail.com
gliorion@icc-al.org
erasmohuertas@hotmail.com/alfredoguz@gmail.com
drtklau@hkparamount.com
gakljubic@gmail.com
pooh27ritsuko@fetal-medicine-pooh.com
profashmaig@hotmail.com
mnmhagra3@gmail.com/jaideepmalhotraagra@gmail.com
sonalyogesh@yahoo.com
ana_tikvica@yahoo.com/oliver.vasilj@gmail.com
amikhailov@AM2697.spb.edu
ampsmpge@hotmail.com
papp.zoltan@maternity.hu
Contd...
iv
Contd...
Azen Salim
Cihat Sen/Murat Yayla
Indonesia
Turkey
azen364@msn.com
csen@perinatal.org.tr, csen@iandonald.org/
myayla99@yahoo.com
florin_stamatian@yahoo.com/vladareanu@gmail.com vdovichenko@perinatolog.com.ua/avt@perinatolog.com.ua
vlai@ukc-mb.si
lvoto@intramed.net/drjorgehamer@hotmail.com
miroslaw.wielgos@wum.edu.pl
ivica.zalud@gmail.com
robertocassis@hotmail.com
harishrestha340@hotmail.com, omhrc@wlink.com.np
emerz@mail.uni-mainz.de
ville.yves@gmail.com
farahnuaimy@yahoo.com
matiasalexand@gmail.com
fmn@ultra-sonografia.com.br
profgilani@gmail.com
snezanacrnogorac1@gmail.com, snezana_cg@yahoo.com
karlerwin64@gmail.com
mruoticosp@gmail.com
cora313@yahoo.com
wahaajhospital@yahoo.com
adramfm@inco.com.lb
elmahaishi@elmahaishi.com
fidaaymen@hotmail.com
hatonguyen@gmail.com/bvtudu@hcm.vnn.vn/
thuky.bgd@tudu.com.vn
moniaferchiou@yahoo.fr/chaabanem@hotmail.fr
twataganara@yahoo.com
yvrq@aol.com
fouedjiojeanne@yahoo.fr
zalel1954@gmail.com
kasak@doctors.org.uk
chechera68@gmail.com
gadamova@hotmail.com
rayalaabc@gmail.com
mvdegtyareva@gmail.com/lalisichinava@gmail.com
waldosep@yahoo.co.uk
josedelancer@yahoo.com, fauzibacha@hotmail.com
lira_kali@mail.ru
gjkim@cau.ac.kr
teutadaullxhiu@hotmail.com, teutadaullxhiu@gmail.com
dayas@mcmaster.ca
roumendim@abv.bg
brincatm@maltanet.net
fatigy@yahoo.com
r_abrahamyan@mail.ru
tamaraillescas@hotmail.com
btulga05@yahoo.com
freddygonarias@gmail.com
Florin Stamatian/Radu Vladareanu
Yuriy P Vdovychenko/Andrew Tkachenko
Veljko Vlaisavljevic
Liliana Voto/Jorge Hamer
Miroslaw Wielgos
Ivica Zalud
Roberto Cassis Martinez
Hari Kishor Shrestha
Eberhard Merz
Yves Ville
Farah Sulaiman Youssif
Alexandra Matias
Francisco Filho Mauad
Syed Amir Gilani
Snezana Crnogorac
Karl Erwin Schweinfurth Alvarado
Miguel Antonio Ruoti Cosp
Corazon Yabes-Almirante
Mohammad Hashim Wahaaj
Abdallah Adra
Mohamed S Elmahaishi
Fida Mahmoud Ahmad Thekrallah
Ha To Nguyen/Pham Viet Thanh
Romania
Ukraine
Slovenia
Argentina
Poland
Honolulu, USA
Ecuador
Nepal
Germany
France
Bahrain
Portugal
Brazil
Pakistan
Montenegro
Honduras
Paraguay
Philippines
Afghanistan
Lebanon
Libya
Jordan
Vietnam
Monia Ferchiou Cherif/Mounira Nouri Chaabane
Tuangsit Wataganara
Ruben Quintero
Jeanne Hortence Fouedjio
Yaron Zalel
Kwabena Appiah-Sakyi
Abdulfetah Abdulkadir
Gordana Adamova
Rodrigo Ayala Yáñez
Marina Degtyareva/Lali Sichinava
Waldo Sepulveda
Jose De Lancer Despradel/Fauzi Bacha Arbaje
Lira Kalieva
Gwang Jun Kim
Teuta Daullxhiu
Salim Daya
Roumen Gueorguiev Dimitrov
Mark P Brincat
Fatma Gahramanli
Ruzanna Abrahamyan
Tamara Illescas Molina
Gendenjamts Battulga
Freddy Gonzalez Arias
Tunisia
Thailand
Miami, USA
Cameroon
Israel
Ghana
Ethiopia
Macedonia
Mexico
Moscow, Russia
Chile
Dominican Republic
Kazakhstan
Korea
Kosovo
Canada
Bulgaria
Malta
Azerbaijan
Armenia
Madrid, Spain
Mongolia
Venezuela
Aliyu Labaran Dayyabu
Mohamed Bayari
Larisa Belotserkovtseva/Tatyana Petrova
Nigeria
Morocco
Surgut, Russia
Firas Jawdat Abdeljawad
William Ching Hua Hsiao
Adolfo Liao
Natalia Bondarenko
Renato Augusto Moreira de Sá
Hisham Ahmad Arab
Raul Moreira Neto
Administrative Secretary of the School
Jadranka Cerovec
Palestine
Taiwan
Sao Paulo, Brazil
Irkutsk, Russia
Rio de Janeiro, Brazil
Jeddah, Saudi Arabia
Porto Alegre, Brazil
zainalabidinaliyu@yahoo.com
mohamed.bayari@gmail.com
info@surgut-kpc.ru, lbelotserkovtseva@gmail.com/
shuvaeva66@mail.ru
dr_firasjawdat@yahoo.com
hsiaochh2866@gmail.com
a.liao@proafeto.com.br, liao@usp.br
bondnatasha@mail.ru
renatosa.uff@gmail.com
arab123@gmail.com
raul@ecomoinhos.com.br, rmneto@cpovo.net
Croatia
jadranka.cerovec@yahoo.com
v
Ian Donald School courses in 2015
Date
vi
City, Country
Number of Participants
February 4-6
Bangkok, Thailand
420
February 21
Athens, Greece
April 10-12
Adana, Turkey
April 15-16
Sarajevo, BIH
April 19
Zagreb, Croatia
May 1-2
Saudi Arabia
May 7-9
Mexico City, Mexico
May 14-16
Ljubljana, Slovenia
May 20-22
Guayaquil, Ecuador
June 11
St. Petersburg, Russia
June 19-21
Cagliari, Italy
August 7-8
Honolulu, Hawaii, USA
September
Jordan
September 25-26
Skopje, Macedonia
October 2-3
Rio de Janeiro, Brazil
October 3-4
Gifu, Japan
November 19-21
Tbilisi, Georgia
December 11-13
Athens, Greece
ANNOUNCEMENT
GLOBAL MARKETING PARTNER
Ian Donald Inter-University School of Medical Ultrasound is pleased to announce that
Dialog India Services Pvt Ltd
Unit No. 5, Gr Floor, Dilkap Chambers
Behind Balaji Telefilms, Veera Desai Rd Extn
Andheri (W), Mumbai-400053, Maharashtra, India
Tel: 66990140/60, Fax: 66990150
Cell: 9004656306
www.dialogindia.com
has been appointed as exclusive global educational marketing partner of the School.
vii
viii
Scientific Program:
Thursday 26th March 2015
Crowne Plaza Hotel Bucharest
08:00-09:00
Registration
09:00
Conference Opening—Welcome Speech
09:15-11:00
Chair: Asim Kurjak, Aida Salihagic-Kadic
09:15-10:00
Introductory Lecture
Fetal neurology—evolving challenges
Asim Kurjak
10:00-10:30
Fetal neurology—the role of fetal stress
Aida Salihagic-Kadic
10:30-11:00
Fetal EEG, Ultrasound and MRI. A new approach for the study of the development of the central nervous
system in utero
Florin Stamatian
11:00-11:20
Coffee break
11:20-11:45
The new paradigm in cervical cancer prevention
Radu Vladareanu
11:45-13:15
Chair: Ritsuko Pooh, Toshiyuki Hata
11:45-12:15
3D Ultrasound Sonoembryology
Ritsuko Pooh
12:15-12:45
HDlive and 4D ultrasound in the assessment of fetal facial expressions
Toshiyuki Hata
12:45-13:15
Magnetic resonance spectroscopy: a promise for detection of metabolic changes in the brain of IUGR
fetuses?
Radu Vladareanu
13:15-13:30
Short break
PHARMA SYMPOSIUMS + LUNCH BOX, Crown A + B + C Hall
13:30-15:30
Chair: Radu Vladareanu, Nicolae Suciu
15:30-17:00
Chair: Milan Stanojevic, Simona Vlădăreanu
15:30-16:00
HDlive and 4D ultrasound assessment of twin pregnancy
Toshiyuki Hata
16:00-16:30
Antenatal and postnatal assessment of neurobehavior—which one should be used?
Milan Stanojevic
16:30-17:00
Fetal isolated mild ventriculomegaly (IMVM)—are there neonatal consequences?
Simona Vladareanu
17:00-17:15
Coffee break
17:15-19:15
Chair: Stefania Tudorache, Panos Antsaklis
17:15-17:45
First trimester diagnosis in isolated open spina bifida
Ștefania Tudorache
17:45-18:15
Controversies surrounding early diagnosis of fetal brain anomalies
Dominic Iliescu
18:15-18:45
Assessment of fetal neurobehavior in diabetic pregnancy
Panos Antsaklis
Friday 27th March 2015
Crowne Plaza Hotel Bucharest
08:30-11:00
Round Table Session
Moderator
Is KANET ready for introduction into clinical practice?
Asim Kurjak
with: Milan Stanojevic, Simona Vladareanu, Ritsuko Pooh, Stefania Tudorache, Florin Stamatian, Panos
Antsaklis, Dominic Iliescu, Toshiyuki Hata, Radu Vladareanu, Raul Moreira Neto
ix
11:00
x
KANET test in fetal anomalies of the CNS
Ritsuko Pooh
KANET in Brasil: First study
Raul Moreira Neto
Conference closing
Donald School Journal of
Ultrasound in Obstetrics and
Gynecology
January-March 2015 Volume 9 Number 1
Contents
Original Article
KANET in Brazil: First Experience................................................................................................ 1-5
Raul Moreira Neto
Review Articles
Fetal Neurology: Past, Present and Future................................................................................... 6-29
Asim Kurjak, Panagiotis Antsaklis, Milan Stanojevic
Fetal Neurology: The Role of Fetal Stress.................................................................................. 30-39
Aida Salihagić Kadić
Magnetic Resonance Spectroscopy: A Promise for Detection of Metabolic
Changes in the Brain of Intrauterine Growth Restriction Fetuses.......................................... 40-43
Vlad Zamfirescu, Radu Vladareanu, Simona Vladareanu
HDlive and 4D Ultrasound in the Assessment of Fetal Facial Expressions............................. 44-50
Toshiyuki Hata, Kenji Kanenishi, Uiko Hanaoka, Genzo Marumo
HDlive and 4D Ultrasound in the Assessment of Twin Pregnancy........................................... 51-60
Toshiyuki Hata, Kenji Kanenishi, Uiko Hanaoka,
Mohamed Ahmed Mostafa AboEllail, Genzo Marumo
Prenatal Development of the Human Central Nervous System,
Normal and Abnormal.................................................................................................................. 61-66
Kohei Shiota
Antenatal and Postnatal Assessment of Neurobehavior: Which One
should be used?............................................................................................................................. 67-74
Milan Stanojevic
Fetal Isolated Ventriculomegaly: Is There any Neonatal Consequences?............................... 75-79
Simona Vladareanu, Vlad Andrei Traistaru, Radu Vladareanu
First Trimester Anomaly Scan—The Last Redoubt Won: Open Spina Bifida ....................... 80-90
Stefania Tudorache, Iliescu Dominic Gabriel, Adina Turcu, Maria Florea,
Roxana Drăgușin, Liliana Novac, Cernea Nicolae, Daniela Cernea
Is in utero Fetal Neurological Assessment Comparable to Postnatal
Neurological Assessment?............................................................................................................ 91-95
Oliver Vasilj
First Experience in Clinical Application of KANET................................................................. 96-99
Ana Tikvica Luetic
Ultrasound in Infertility........................................................................................................... 100-110
Sonal Panchal, CB Nagori
xii